Published in Clin Cancer Res on May 05, 2009
Barrett's oesophagus and oesophageal adenocarcinoma: time for a new synthesis. Nat Rev Cancer (2010) 3.27
Predictors of progression in Barrett's esophagus: current knowledge and future directions. Am J Gastroenterol (2010) 1.35
Next-generation sequencing of endoscopic biopsies identifies ARID1A as a tumor-suppressor gene in Barrett's esophagus. Oncogene (2013) 1.33
Genome-wide catalogue of chromosomal aberrations in barrett's esophagus and esophageal adenocarcinoma: a high-density single nucleotide polymorphism array analysis. Cancer Prev Res (Phila) (2010) 1.12
The microRNAs, MiR-31 and MiR-375, as candidate markers in Barrett's esophageal carcinogenesis. Genes Chromosomes Cancer (2012) 1.06
Genomic evolution in Barrett's adenocarcinoma cells: critical roles of elevated hsRAD51, homologous recombination and Alu sequences in the genome. Oncogene (2011) 1.04
NSAIDs modulate clonal evolution in Barrett's esophagus. PLoS Genet (2013) 0.98
New strategies in Barrett's esophagus: integrating clonal evolutionary theory with clinical management. Clin Cancer Res (2011) 0.96
Whole genome expression array profiling highlights differences in mucosal defense genes in Barrett's esophagus and esophageal adenocarcinoma. PLoS One (2011) 0.94
Prolonged exposure to acid and bile induces chromosome abnormalities that precede malignant transformation of benign Barrett's epithelium. Mol Cytogenet (2012) 0.93
Integrative genomics identified RFC3 as an amplified candidate oncogene in esophageal adenocarcinoma. Clin Cancer Res (2012) 0.89
Comparison of nuclear texture analysis and image cytometric DNA analysis for the assessment of dysplasia in Barrett's oesophagus. Br J Cancer (2011) 0.88
Integrative post-genome-wide association analysis of CDKN2A and TP53 SNPs and risk of esophageal adenocarcinoma. Carcinogenesis (2014) 0.87
Comparison of cancer-associated genetic abnormalities in columnar-lined esophagus tissues with and without goblet cells. Ann Surg (2014) 0.85
A Multiscale Model Evaluates Screening for Neoplasia in Barrett's Esophagus. PLoS Comput Biol (2015) 0.84
Transcribed ultraconserved noncoding RNAs (T-UCR) are involved in Barrett's esophagus carcinogenesis. Oncotarget (2014) 0.84
The Presence of Genetic Mutations at Key Loci Predicts Progression to Esophageal Adenocarcinoma in Barrett's Esophagus. Am J Gastroenterol (2015) 0.83
RAF-kinase inhibitor protein (RKIP) downregulation in esophageal cancer and its metastases. Clin Exp Metastasis (2012) 0.83
Early events during neoplastic progression in Barrett's esophagus. Cancer Biomark (2010) 0.83
Characterization of chromosomal instability in murine colitis-associated colorectal cancer. PLoS One (2011) 0.82
Genetic Insights in Barrett's Esophagus and Esophageal Adenocarcinoma. Gastroenterology (2015) 0.81
Targeting chemokine pathways in esophageal adenocarcinoma. Cell Cycle (2014) 0.79
Genetic Biomarkers of Barrett's Esophagus Susceptibility and Progression to Dysplasia and Cancer: A Systematic Review and Meta-Analysis. Dig Dis Sci (2015) 0.79
Predictive biomarkers for Barrett's esophagus: so near and yet so far. Dis Esophagus (2013) 0.78
Biomarkers of Barrett's esophagus. World J Gastrointest Pathophysiol (2014) 0.77
Copy number alterations detected by whole-exome and whole-genome sequencing of esophageal adenocarcinoma. Hum Genomics (2015) 0.77
Barrett's Esophagus: A Review of Biology and Therapeutic Approaches. Gastrointest Cancer Res (2012) 0.76
Integrated molecular analysis reveals complex interactions between genomic and epigenomic alterations in esophageal adenocarcinomas. Sci Rep (2017) 0.75
Medical and endoscopic management of high-grade dysplasia in Barrett's esophagus. Dis Esophagus (2012) 0.75
Reduced genomic tumor heterogeneity after neoadjuvant chemotherapy is related to favorable outcome in patients with esophageal adenocarcinoma. Oncotarget (2016) 0.75
Biomarkers in Barrett's Esophagus. Tech Gastrointest Endosc (2010) 0.75
Long Noncoding RNAs in the Pathogenesis of Barrett's Esophagus and Esophageal Carcinoma. Gastroenterology (2017) 0.75
Early detection: the impact of genomics. Virchows Arch (2017) 0.75
Global variation in copy number in the human genome. Nature (2006) 57.50
Detection of large-scale variation in the human genome. Nat Genet (2004) 49.18
The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus. Am J Gastroenterol (2006) 12.80
Phases of biomarker development for early detection of cancer. J Natl Cancer Inst (2001) 10.37
The role of overdiagnosis and reclassification in the marked increase of esophageal adenocarcinoma incidence. J Natl Cancer Inst (2005) 8.90
Updated guidelines 2008 for the diagnosis, surveillance and therapy of Barrett's esophagus. Am J Gastroenterol (2008) 7.94
Long-term nonsurgical management of Barrett's esophagus with high-grade dysplasia. Gastroenterology (2001) 5.80
Reproducibility of the diagnosis of dysplasia in Barrett esophagus: a reaffirmation. Hum Pathol (2001) 4.16
Genomic microarrays in human genetic disease and cancer. Hum Mol Genet (2003) 4.15
Epidemiologic trends in esophageal and gastric cancer in the United States. Surg Oncol Clin N Am (2002) 3.69
Observer variation in the diagnosis of dysplasia in Barrett's esophagus. Hum Pathol (1988) 3.67
A critical review of the diagnosis and management of Barrett's esophagus: the AGA Chicago Workshop. Gastroenterology (2004) 3.50
Predictors of progression to cancer in Barrett's esophagus: baseline histology and flow cytometry identify low- and high-risk patient subsets. Am J Gastroenterol (2000) 2.99
Array comparative genomic hybridization analysis of genomic alterations in breast cancer subtypes. Cancer Res (2004) 2.80
Denoising array-based comparative genomic hybridization data using wavelets. Biostatistics (2005) 2.56
NSAIDs modulate CDKN2A, TP53, and DNA content risk for progression to esophageal adenocarcinoma. PLoS Med (2007) 2.23
Predictors of progression in Barrett's esophagus III: baseline flow cytometric variables. Am J Gastroenterol (2001) 2.21
Selectively advantageous mutations and hitchhikers in neoplasms: p16 lesions are selected in Barrett's esophagus. Cancer Res (2004) 2.15
Whole chromosome instability and cancer: a complex relationship. Trends Genet (2008) 2.04
Chromosomal imbalances in human lung cancer. Oncogene (2002) 2.00
Defining 'chromosomal instability'. Trends Genet (2008) 1.76
Cyclooxygenases in cancer: progress and perspective. Cancer Lett (2004) 1.74
Genetic differences between adenocarcinomas arising in Barrett's esophagus and gastric mucosa. Gastroenterology (2001) 1.74
Gene amplification in esophageal adenocarcinomas and Barrett's with high-grade dysplasia. Clin Cancer Res (2003) 1.62
Mortality in Barrett's oesophagus: results from a population based study. Gut (2003) 1.60
Chromosomal imbalances in Barrett's adenocarcinoma and the metaplasia-dysplasia-carcinoma sequence. Am J Pathol (2000) 1.57
Meta analysis: Cancer risk in Barrett's oesophagus. Aliment Pharmacol Ther (2007) 1.50
Genome-wide copy number analysis in esophageal adenocarcinoma using high-density single-nucleotide polymorphism arrays. Cancer Res (2008) 1.50
Single nucleotide polymorphism-based genome-wide chromosome copy change, loss of heterozygosity, and aneuploidy in Barrett's esophagus neoplastic progression. Cancer Prev Res (Phila) (2008) 1.43
Genetic pathways involved in the progression of Barrett's metaplasia to adenocarcinoma. Br J Surg (2002) 1.40
Clinical significance of epidermal growth factor receptor protein overexpression and gene copy number gains in prostate cancer. Clin Cancer Res (2007) 1.36
Biomarkers in Barrett's esophagus. Gastrointest Endosc Clin N Am (2003) 1.36
Risk of mortality and cancer incidence in Barrett's esophagus. Cancer Epidemiol Biomarkers Prev (2007) 1.29
Increasing genomic instability during premalignant neoplastic progression revealed through high resolution array-CGH. Genes Chromosomes Cancer (2007) 1.26
Comparative genomic hybridization of cancer of the gastroesophageal junction: deletion of 14Q31-32.1 discriminates between esophageal (Barrett's) and gastric cardia adenocarcinomas. Cancer Res (1999) 1.18
DNA/protein flow cytometry as a predictive marker of malignancy in dysplasia-free Barrett's esophagus: thirteen-year follow-up study on a cohort of patients. Cytometry (1998) 1.13
Genomic alterations in malignant transformation of Barrett's esophagus. Cancer Res (2001) 1.12
Comparative genomic hybridization of esophageal and gastroesophageal adenocarcinomas shows consensus areas of DNA gain and loss. Genes Chromosomes Cancer (1998) 1.04
Genetic mechanisms of TP53 loss of heterozygosity in Barrett's esophagus: implications for biomarker validation. Cancer Epidemiol Biomarkers Prev (2006) 0.98
Cyclooxygenase-2 and gastrointestinal cancer. Cancer J (2004) 0.94
Array-based comparative genomic hybridization for the detection of DNA sequence copy number changes in Barrett's adenocarcinoma. J Pathol (2004) 0.93
Chromosome 4 hyperploidy represents an early genetic aberration in premalignant Barrett's oesophagus. Gut (2003) 0.93
COX2 expression, angiogenesis, proliferation and survival in Barrett's cancer. Eur J Surg Oncol (2005) 0.92
Systematic review: Cyclo-oxygenase-2 in human oesophageal adenocarcinogenesis. Aliment Pharmacol Ther (2006) 0.91
Genomic array and expression analysis of frequent high-level amplifications in adenocarcinomas of the gastro-esophageal junction. Cancer Genet Cytogenet (2006) 0.90
DNA copy number profiling in esophageal Barrett adenocarcinoma: comparison with gastric adenocarcinoma and esophageal squamous cell carcinoma. Cancer Genet Cytogenet (2001) 0.89
Analysis of the premalignant stages of Barrett's oesophagus through to adenocarcinoma by comparative genomic hybridization. Eur J Gastroenterol Hepatol (2002) 0.89
Genomic analysis of early adenocarcinoma of the esophagus or gastroesophageal junction: tumor progression is associated with alteration of 1q and 8p sequences. Genes Chromosomes Cancer (2006) 0.83
Comparative genomic hybridization (CGH): ten years of substantial progress in human solid tumor molecular cytogenetics. Cytogenet Genome Res (2004) 0.80
Defective mismatch-repair as a minor tumorigenic pathway in Barrett esophagus-associated adenocarcinoma. Cancer Genet Cytogenet (2005) 0.80
Risk factors for neoplastic progression in Barrett's mucosa. Eur J Surg Oncol (1996) 0.78
Linking long-term dietary patterns with gut microbial enterotypes. Science (2011) 17.30
Eosinophilic esophagitis: updated consensus recommendations for children and adults. J Allergy Clin Immunol (2011) 12.48
Clonal evolution in cancer. Nature (2012) 11.07
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis. Nat Med (2013) 9.44
Cancer as an evolutionary and ecological process. Nat Rev Cancer (2006) 9.33
Genetic clonal diversity predicts progression to esophageal adenocarcinoma. Nat Genet (2006) 6.71
The transmissibility and control of pandemic influenza A (H1N1) virus. Science (2009) 6.53
Network-constrained regularization and variable selection for analysis of genomic data. Bioinformatics (2008) 6.01
Sampling and pyrosequencing methods for characterizing bacterial communities in the human gut using 16S sequence tags. BMC Microbiol (2010) 4.97
High frequency targeted mutagenesis in Arabidopsis thaliana using zinc finger nucleases. Proc Natl Acad Sci U S A (2010) 4.78
Serrated lesions of the colorectum: review and recommendations from an expert panel. Am J Gastroenterol (2012) 4.22
Variants of DENND1B associated with asthma in children. N Engl J Med (2009) 4.18
Clustering of time-course gene expression data using a mixed-effects model with B-splines. Bioinformatics (2003) 4.15
Copy number variation at 1q21.1 associated with neuroblastoma. Nature (2009) 4.10
Chromosome 6p22 locus associated with clinically aggressive neuroblastoma. N Engl J Med (2008) 3.80
Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms. Gastroenterology (2003) 3.58
Penalized Cox regression analysis in the high-dimensional and low-sample size settings, with applications to microarray gene expression data. Bioinformatics (2005) 3.34
The human gut virome: inter-individual variation and dynamic response to diet. Genome Res (2011) 3.32
Transcolonic endoscopic cholecystectomy: a NOTES survival study in a porcine model (with video). Gastrointest Endosc (2006) 3.32
Barrett's oesophagus and oesophageal adenocarcinoma: time for a new synthesis. Nat Rev Cancer (2010) 3.27
Metaplastic esophageal columnar epithelium without goblet cells shows DNA content abnormalities similar to goblet cell-containing epithelium. Am J Gastroenterol (2009) 3.18
Epidemiology and pathogenesis of esophageal cancer. Semin Radiat Oncol (2007) 3.18
Population attributable risks of esophageal and gastric cancers. J Natl Cancer Inst (2003) 3.07
Group SCAD regression analysis for microarray time course gene expression data. Bioinformatics (2007) 3.04
Extent of low-grade dysplasia is a risk factor for the development of esophageal adenocarcinoma in Barrett's esophagus. Am J Gastroenterol (2007) 3.00
A Markov random field model for network-based analysis of genomic data. Bioinformatics (2007) 2.93
Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes. Cancer Res (2006) 2.92
Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow. Cell (2008) 2.84
Maternal malaria and gravidity interact to modify infant susceptibility to malaria. PLoS Med (2005) 2.72
Disordered microbial communities in the upper respiratory tract of cigarette smokers. PLoS One (2010) 2.60
Variable Selection in Nonparametric Varying-Coefficient Models for Analysis of Repeated Measurements. J Am Stat Assoc (2008) 2.50
Peto's Paradox: evolution's prescription for cancer prevention. Trends Ecol Evol (2011) 2.48
Common variations in BARD1 influence susceptibility to high-risk neuroblastoma. Nat Genet (2009) 2.47
Strategies for pandemic and seasonal influenza vaccination of schoolchildren in the United States. Am J Epidemiol (2009) 2.47
Non-steroidal anti-inflammatory drugs and risk of neoplastic progression in Barrett's oesophagus: a prospective study. Lancet Oncol (2005) 2.40
Leukocyte telomere length predicts cancer risk in Barrett's esophagus. Cancer Epidemiol Biomarkers Prev (2007) 2.39
Transcription activator-like effector nucleases enable efficient plant genome engineering. Plant Physiol (2012) 2.36
AGA technical review on the diagnosis and management of colorectal neoplasia in inflammatory bowel disease. Gastroenterology (2010) 2.31
Ethnic-difference markers for use in mapping by admixture linkage disequilibrium. Am J Hum Genet (2002) 2.29
Nonparametric pathway-based regression models for analysis of genomic data. Biostatistics (2006) 2.28
Progress in chemoprevention drug development: the promise of molecular biomarkers for prevention of intraepithelial neoplasia and cancer--a plan to move forward. Clin Cancer Res (2006) 2.24
NSAIDs modulate CDKN2A, TP53, and DNA content risk for progression to esophageal adenocarcinoma. PLoS Med (2007) 2.23
Gene expression analyzed by high-resolution state array analysis and quantitative proteomics: response of yeast to mating pheromone. Mol Cell Proteomics (2004) 2.22
Integrative genomics identifies LMO1 as a neuroblastoma oncogene. Nature (2010) 2.21
Central adiposity and risk of Barrett's esophagus. Gastroenterology (2007) 2.20
Associating microbiome composition with environmental covariates using generalized UniFrac distances. Bioinformatics (2012) 2.19
Selectively advantageous mutations and hitchhikers in neoplasms: p16 lesions are selected in Barrett's esophagus. Cancer Res (2004) 2.15
AGA medical position statement on the diagnosis and management of colorectal neoplasia in inflammatory bowel disease. Gastroenterology (2010) 2.09
Carbonated soft drink consumption and risk of esophageal adenocarcinoma. J Natl Cancer Inst (2006) 2.08
Properties of the neosquamous epithelium after radiofrequency ablation of Barrett's esophagus containing neoplasia. Am J Gastroenterol (2009) 2.05
Racial disparities among patients with lung cancer who were recommended operative therapy. Arch Surg (2009) 2.02
A functional polymorphism of toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors. Gastroenterology (2006) 1.98
Analysis of inflammatory cytokines in the tears of dry eye patients. Cornea (2009) 1.96
Definition of Barrett's esophagus: time for a rethink--is intestinal metaplasia dead? Am J Gastroenterol (2009) 1.93
A comprehensive survey of clonal diversity measures in Barrett's esophagus as biomarkers of progression to esophageal adenocarcinoma. Cancer Prev Res (Phila) (2010) 1.89
Morphology of the cardia and significance of carditis in pediatric patients. Am J Surg Pathol (2002) 1.79
The combination of genetic instability and clonal expansion predicts progression to esophageal adenocarcinoma. Cancer Res (2004) 1.76
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands. Proc Natl Acad Sci U S A (2010) 1.73
A likelihood-based approach to mixed modeling with ambiguity in cluster identifiers. Biostatistics (2008) 1.72
EMR for Barrett's esophagus-related superficial neoplasms offers better diagnostic reproducibility than mucosal biopsy. Gastrointest Endosc (2007) 1.70
Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response. Proc Natl Acad Sci U S A (2009) 1.69
Trends in the utilization and impact of radiofrequency ablation for hepatocellular carcinoma. J Am Coll Surg (2010) 1.68
A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus. Nat Genet (2013) 1.67
Solitary versus multiple carcinoid tumors of the ileum: a clinical and pathologic review of 68 cases. Am J Surg Pathol (2003) 1.66