Interactions between Swi1-Swi3, Mrc1 and S phase kinase, Hsk1 may regulate cellular responses to stalled replication forks in fission yeast.

PubWeight™: 1.12‹?› | Rank: Top 10%

🔗 View Article (PMC 2837079)

Published in Genes Cells on April 30, 2009

Authors

Michie Shimmoto1, Seiji Matsumoto, Yukari Odagiri, Eishi Noguchi, Paul Russell, Hisao Masai

Author Affiliations

1: Genome Dynamics Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 113-8613, Japan.

Articles citing this

RNAi promotes heterochromatic silencing through replication-coupled release of RNA Pol II. Nature (2011) 1.79

Temporospatial coordination of meiotic DNA replication and recombination via DDK recruitment to replisomes. Cell (2014) 1.74

Hsk1- and SCF(Pof3)-dependent proteolysis of S. pombe Ams2 ensures histone homeostasis and centromere function. Dev Cell (2010) 1.68

Hsk1 kinase and Cdc45 regulate replication stress-induced checkpoint responses in fission yeast. Cell Cycle (2010) 1.58

Local and global functions of Timeless and Tipin in replication fork protection. Cell Cycle (2012) 1.15

Self-organization of meiotic recombination initiation: general principles and molecular pathways. Annu Rev Genet (2014) 1.10

Mrc1 marks early-firing origins and coordinates timing and efficiency of initiation in fission yeast. Mol Cell Biol (2011) 0.92

Fission yeast Swi1-Swi3 complex facilitates DNA binding of Mrc1. J Biol Chem (2010) 0.90

Checkpoint-independent Regulation of Origin Firing by Mrc1 through Interaction with Hsk1 kinase. Mol Cell Biol (2017) 0.88

Checkpoint-dependent and -independent roles of Swi3 in replication fork recovery and sister chromatid cohesion in fission yeast. PLoS One (2010) 0.87

The double-bromodomain proteins Bdf1 and Bdf2 modulate chromatin structure to regulate S-phase stress response in Schizosaccharomyces pombe. Genetics (2011) 0.85

Multiple pathways can bypass the essential role of fission yeast Hsk1 kinase in DNA replication initiation. J Cell Biol (2011) 0.84

Coordinated degradation of replisome components ensures genome stability upon replication stress in the absence of the replication fork protection complex. PLoS Genet (2013) 0.84

Mms1 and Mms22 stabilize the replisome during replication stress. Mol Biol Cell (2011) 0.84

Swi1 associates with chromatin through the DDT domain and recruits Swi3 to preserve genomic integrity. PLoS One (2012) 0.83

Claspin recruits Cdc7 kinase for initiation of DNA replication in human cells. Nat Commun (2016) 0.82

The fission yeast minichromosome maintenance (MCM)-binding protein (MCM-BP), Mcb1, regulates MCM function during prereplicative complex formation in DNA replication. J Biol Chem (2013) 0.81

CDC28 phosphorylates Cac1p and regulates the association of chromatin assembly factor I with chromatin. Cell Cycle (2015) 0.79

Proteasome-dependent degradation of replisome components regulates faithful DNA replication. Cell Cycle (2013) 0.78

A genetic screen for replication initiation defective (rid) mutants in Schizosaccharomyces pombe. Cell Div (2010) 0.77

The subunits of the S-phase checkpoint complex Mrc1/Tof1/Csm3: dynamics and interdependence. Cell Div (2014) 0.76

The DNA-Binding Domain of S. pombe Mrc1 (Claspin) Acts to Enhance Stalling at Replication Barriers. PLoS One (2015) 0.76

Mrc1/Claspin: a new role for regulation of origin firing. Curr Genet (2017) 0.75

Articles cited by this

Cell-cycle checkpoints and cancer. Nature (2004) 13.19

S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex. Nature (2003) 6.43

GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks. Nat Cell Biol (2006) 6.36

Mrc1 transduces signals of DNA replication stress to activate Rad53. Nat Cell Biol (2001) 5.05

Cdc7p-Dbf4p kinase binds to chromatin during S phase and is regulated by both the APC and the RAD53 checkpoint pathway. EMBO J (1999) 3.03

An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication. Mol Cell (2003) 2.96

SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response. Mol Cell (2006) 2.75

Adaptation of a DNA replication checkpoint response depends upon inactivation of Claspin by the Polo-like kinase. Cell (2004) 2.75

Mrc1 channels the DNA replication arrest signal to checkpoint kinase Cds1. Nat Cell Biol (2001) 2.62

Swi1 and Swi3 are components of a replication fork protection complex in fission yeast. Mol Cell Biol (2004) 2.55

The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement. Mol Cell Biol (2007) 2.54

Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress. Mol Cell (2006) 2.45

Swi1 prevents replication fork collapse and controls checkpoint kinase Cds1. Mol Cell Biol (2003) 2.19

Phosphorylation of MCM4 by Cdc7 kinase facilitates its interaction with Cdc45 on the chromatin. J Biol Chem (2006) 2.14

Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery. Curr Biol (2006) 2.02

Chromatin binding of the fission yeast replication factor mcm4 occurs during anaphase and requires ORC and cdc18. EMBO J (2000) 1.91

hsk1+, a Schizosaccharomyces pombe gene related to Saccharomyces cerevisiae CDC7, is required for chromosomal replication. EMBO J (1995) 1.89

Human Cdc7-related kinase complex. In vitro phosphorylation of MCM by concerted actions of Cdks and Cdc7 and that of a criticial threonine residue of Cdc7 bY Cdks. J Biol Chem (2000) 1.85

Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function. Proc Natl Acad Sci U S A (2006) 1.81

Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7. EMBO J (1997) 1.78

DNA replication checkpoint. Curr Biol (2001) 1.76

Uncoupling of unwinding from DNA synthesis implies regulation of MCM helicase by Tof1/Mrc1/Csm3 checkpoint complex. J Mol Biol (2005) 1.74

Cdc7 kinase complex: a key regulator in the initiation of DNA replication. J Cell Physiol (2002) 1.68

Rad17 phosphorylation is required for claspin recruitment and Chk1 activation in response to replication stress. Mol Cell (2006) 1.65

Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint. J Biol Chem (2006) 1.62

An N-terminal domain of Dbf4p mediates interaction with both origin recognition complex (ORC) and Rad53p and can deregulate late origin firing. Proc Natl Acad Sci U S A (2002) 1.55

Hsk1-Dfp1 is required for heterochromatin-mediated cohesion at centromeres. Nat Cell Biol (2003) 1.54

Regulation of initiation of S phase, replication checkpoint signaling, and maintenance of mitotic chromosome structures during S phase by Hsk1 kinase in the fission yeast. Mol Biol Cell (2001) 1.42

Tipin, a novel timeless-interacting protein, is developmentally co-expressed with timeless and disrupts its self-association. J Mol Biol (2003) 1.40

A fission yeast gene, him1(+)/dfp1(+), encoding a regulatory subunit for Hsk1 kinase, plays essential roles in S-phase initiation as well as in S-phase checkpoint control and recovery from DNA damage. Mol Cell Biol (1999) 1.39

Schizosaccharomyces pombe Swi1, Swi3, and Hsk1 are components of a novel S-phase response pathway to alkylation damage. Mol Cell Biol (2005) 1.37

Hsk1-Dfp1/Him1, the Cdc7-Dbf4 kinase in Schizosaccharomyces pombe, associates with Swi1, a component of the replication fork protection complex. J Biol Chem (2005) 1.30

Cdc7 kinase mediates Claspin phosphorylation in DNA replication checkpoint. Oncogene (2007) 1.26

Cell cycle regulation of Dfp1, an activator of the Hsk1 protein kinase. Proc Natl Acad Sci U S A (1999) 1.26

Schizosaccharomyces pombe Hsk1p is a potential cds1p target required for genome integrity. Mol Cell Biol (2000) 1.24

Replication checkpoint protein Mrc1 is regulated by Rad3 and Tel1 in fission yeast. Mol Cell Biol (2003) 1.20

Inactivation of Cdc7 kinase in mouse ES cells results in S-phase arrest and p53-dependent cell death. EMBO J (2002) 1.06

Hsk1 kinase is required for induction of meiotic dsDNA breaks without involving checkpoint kinases in fission yeast. Proc Natl Acad Sci U S A (2006) 1.00

DNA binding domain in the replication checkpoint protein Mrc1 of Schizosaccharomyces pombe. J Biol Chem (2004) 0.98

Articles by these authors

Visualizing spatiotemporal dynamics of multicellular cell-cycle progression. Cell (2008) 10.49

Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination. Mol Cell (2007) 5.31

Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases. Cell (2009) 5.05

Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair. Cell (2008) 4.26

ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1. Mol Cell Biol (2005) 3.25

Elastic modulus determination of normal and glaucomatous human trabecular meshwork. Invest Ophthalmol Vis Sci (2011) 3.19

Eukaryotic chromosome DNA replication: where, when, and how? Annu Rev Biochem (2010) 3.17

Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair. Cell (2009) 2.90

Swi1 and Swi3 are components of a replication fork protection complex in fission yeast. Mol Cell Biol (2004) 2.55

Fission yeast Scm3 mediates stable assembly of Cnp1/CENP-A into centromeric chromatin. Mol Cell (2009) 2.49

The endogenous Mus81-Eme1 complex resolves Holliday junctions by a nick and counternick mechanism. Mol Cell (2003) 2.44

UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit. Nat Cell Biol (2009) 2.29

Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks. Genes Dev (2006) 2.27

Cid13 is a cytoplasmic poly(A) polymerase that regulates ribonucleotide reductase mRNA. Cell (2002) 2.23

Histone H2A phosphorylation controls Crb2 recruitment at DNA breaks, maintains checkpoint arrest, and influences DNA repair in fission yeast. Mol Cell Biol (2004) 2.20

Swi1 prevents replication fork collapse and controls checkpoint kinase Cds1. Mol Cell Biol (2003) 2.19

Circulating tumor cell as a diagnostic marker in primary lung cancer. Clin Cancer Res (2009) 2.14

Phosphorylation of MCM4 by Cdc7 kinase facilitates its interaction with Cdc45 on the chromatin. J Biol Chem (2006) 2.14

The DNA damage response: sensing and signaling. Curr Opin Cell Biol (2004) 2.13

Nocturia and sleep quality after transurethral resection of the prostate. Int J Urol (2013) 2.03

Slx1-Slx4 are subunits of a structure-specific endonuclease that maintains ribosomal DNA in fission yeast. Mol Biol Cell (2003) 1.96

Constraining G1-specific transcription to late G1 phase: the MBF-associated corepressor Nrm1 acts via negative feedback. Mol Cell (2006) 1.92

Rif1 regulates the replication timing domains on the human genome. EMBO J (2012) 1.87

Epigenetic regulation of condensin-mediated genome organization during the cell cycle and upon DNA damage through histone H3 lysine 56 acetylation. Mol Cell (2012) 1.85

Telomere binding of checkpoint sensor and DNA repair proteins contributes to maintenance of functional fission yeast telomeres. Genetics (2002) 1.78

Fission yeast Mus81.Eme1 Holliday junction resolvase is required for meiotic crossing over but not for gene conversion. Genetics (2003) 1.72

Protection of telomeres by a conserved Stn1-Ten1 complex. Proc Natl Acad Sci U S A (2007) 1.71

Retention but not recruitment of Crb2 at double-strand breaks requires Rad1 and Rad3 complexes. Mol Cell Biol (2003) 1.70

Indentation versus tensile measurements of Young's modulus for soft biological tissues. Tissue Eng Part B Rev (2011) 1.69

Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks. PLoS Genet (2011) 1.66

ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair. Nat Struct Mol Biol (2011) 1.66

Activation of bone marrow-resident memory T cells by circulating, antigen-bearing dendritic cells. Nat Immunol (2005) 1.65

Mus81 is essential for sister chromatid recombination at broken replication forks. EMBO J (2008) 1.63

Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint. J Biol Chem (2006) 1.62

Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stress. Genes Dev (2005) 1.60

Cdc7-dependent phosphorylation of Mer2 facilitates initiation of yeast meiotic recombination. Genes Dev (2008) 1.60

Hsk1 kinase and Cdc45 regulate replication stress-induced checkpoint responses in fission yeast. Cell Cycle (2010) 1.58

Rif1 is a global regulator of timing of replication origin firing in fission yeast. Genes Dev (2012) 1.57

Perisinusoidal B cells in the bone marrow participate in T-independent responses to blood-borne microbes. Immunity (2005) 1.54

Differential arrival of leading and lagging strand DNA polymerases at fission yeast telomeres. EMBO J (2009) 1.54

DDK phosphorylates checkpoint clamp component Rad9 and promotes its release from damaged chromatin. Mol Cell (2010) 1.53

Replication checkpoint kinase Cds1 regulates recombinational repair protein Rad60. Mol Cell Biol (2003) 1.50

Frequent inactivation of the BAP1 gene in epithelioid-type malignant mesothelioma. Cancer Sci (2012) 1.49

Burkholderia pseudomallei: animal models of infection. Trans R Soc Trop Med Hyg (2008) 1.48

Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion. J Cell Sci (2010) 1.47

Sws1 is a conserved regulator of homologous recombination in eukaryotic cells. EMBO J (2006) 1.46

The fission yeast Rad32 (Mre11)-Rad50-Nbs1 complex is required for the S-phase DNA damage checkpoint. Mol Cell Biol (2003) 1.45

Cell cycle and developmental regulations of replication factors in mouse embryonic stem cells. J Biol Chem (2005) 1.43

Effect of tamsulosin on bladder blood flow and bladder function in a rat model of bladder over distention/emptying induced bladder overactivity. J Urol (2011) 1.43

Urodynamic effects of dutasteride add-on therapy to alpha-adrenergic antagonist for patients with benign prostatic enlargement: prospective pressure-flow study. Neurourol Urodyn (2013) 1.41

The impact of abdominal aortic calcification and visceral fat obesity on lower urinary tract symptoms in patients with benign prostatic hyperplasia. Int Urol Nephrol (2014) 1.41

Homo-oligomerization is the essential function of the tandem BRCT domains in the checkpoint protein Crb2. J Biol Chem (2004) 1.41

Characterisation of an acapsular mutant of Burkholderia pseudomallei identified by signature tagged mutagenesis. J Med Microbiol (2002) 1.37

RNA-binding protein Csx1 mediates global control of gene expression in response to oxidative stress. EMBO J (2003) 1.35

Gene and protein expression changes in human trabecular meshwork cells treated with transforming growth factor-beta. Invest Ophthalmol Vis Sci (2004) 1.35

Naive recirculating B cells mature simultaneously in the spleen and bone marrow. Blood (2006) 1.31

Hsk1-Dfp1/Him1, the Cdc7-Dbf4 kinase in Schizosaccharomyces pombe, associates with Swi1, a component of the replication fork protection complex. J Biol Chem (2005) 1.30

gammaH2A binds Brc1 to maintain genome integrity during S-phase. EMBO J (2010) 1.28

The effect of biophysical attributes of the ocular trabecular meshwork associated with glaucoma on the cell response to therapeutic agents. Biomaterials (2011) 1.28

Regulatory networks integrating cell cycle control with DNA damage checkpoints and double-strand break repair. Philos Trans R Soc Lond B Biol Sci (2011) 1.27

RFCCtf18 and the Swi1-Swi3 complex function in separate and redundant pathways required for the stabilization of replication forks to facilitate sister chromatid cohesion in Schizosaccharomyces pombe. Mol Biol Cell (2007) 1.25

Thymine-rich single-stranded DNA activates Mcm4/6/7 helicase on Y-fork and bubble-like substrates. EMBO J (2003) 1.25

CDK phosphorylation of Drc1 regulates DNA replication in fission yeast. Curr Biol (2002) 1.22

Replication checkpoint protein Mrc1 is regulated by Rad3 and Tel1 in fission yeast. Mol Cell Biol (2003) 1.20

Roles of Mcm7 and Mcm4 subunits in the DNA helicase activity of the mouse Mcm4/6/7 complex. J Biol Chem (2002) 1.20

Upf1, an RNA helicase required for nonsense-mediated mRNA decay, modulates the transcriptional response to oxidative stress in fission yeast. Mol Cell Biol (2006) 1.18

RNA interference inhibition of Mus81 reduces mitotic recombination in human cells. Mol Biol Cell (2003) 1.17

Timeless preserves telomere length by promoting efficient DNA replication through human telomeres. Cell Cycle (2012) 1.16

Replisome progression complex links DNA replication to sister chromatid cohesion in Xenopus egg extracts. Genes Cells (2009) 1.15

Local and global functions of Timeless and Tipin in replication fork protection. Cell Cycle (2012) 1.15

Gene expression profiling of TGFbeta2- and/or BMP7-treated trabecular meshwork cells: Identification of Smad7 as a critical inhibitor of TGF-beta2 signaling. Exp Eye Res (2009) 1.14

ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling. EMBO J (2014) 1.14

The mRNA of the translationally controlled tumor protein P23/TCTP is a highly structured RNA, which activates the dsRNA-dependent protein kinase PKR. RNA (2002) 1.13

Cooperative control of Crb2 by ATM family and Cdc2 kinases is essential for the DNA damage checkpoint in fission yeast. Mol Cell Biol (2005) 1.13

Tonoplast-localized Abc2 transporter mediates phytochelatin accumulation in vacuoles and confers cadmium tolerance. J Biol Chem (2010) 1.12

Signaling pathways that regulate cell division. Cold Spring Harb Perspect Biol (2012) 1.12

Effect of latanoprost on the expression of matrix metalloproteinases and their tissue inhibitors in human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2006) 1.12

Rad3 decorates critical chromosomal domains with gammaH2A to protect genome integrity during S-Phase in fission yeast. PLoS Genet (2010) 1.11

The effect of ovariectomy and estradiol on rabbit bladder smooth muscle contraction and morphology. J Urol (2003) 1.11

Compliance profile of the human cornea as measured by atomic force microscopy. Micron (2012) 1.10

Human origins of DNA replication selected from a library of nascent DNA. Mol Cell (2005) 1.09

Replication timing regulation of eukaryotic replicons: Rif1 as a global regulator of replication timing. Trends Genet (2013) 1.07

Alterations in gene expression of human vascular endothelial cells associated with nanotopographic cues. Biomaterials (2010) 1.07

Biological properties of trabecular meshwork cells. Exp Eye Res (2008) 1.06

Inactivation of Cdc7 kinase in mouse ES cells results in S-phase arrest and p53-dependent cell death. EMBO J (2002) 1.06

Phosphorylated Rad18 directs DNA polymerase η to sites of stalled replication. J Cell Biol (2010) 1.06

The applications of atomic force microscopy to vision science. Invest Ophthalmol Vis Sci (2010) 1.06

Rad22Rad52-dependent repair of ribosomal DNA repeats cleaved by Slx1-Slx4 endonuclease. Mol Biol Cell (2006) 1.05

Functions of mammalian Cdc7 kinase in initiation/monitoring of DNA replication and development. Mutat Res (2003) 1.05

Substratum stiffness and latrunculin B regulate matrix gene and protein expression in human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2012) 1.05

Distinct signaling pathways respond to arsenite and reactive oxygen species in Schizosaccharomyces pombe. Eukaryot Cell (2005) 1.04

Donor corneoscleral buttons: a new source of trabecular meshwork for research. Exp Eye Res (2003) 1.04

The matricellular protein SPARC is expressed in human trabecular meshwork. Exp Eye Res (2003) 1.04