Published in J Infect Dis on March 15, 2009
Genetically engineered, attenuated whole-cell vaccine approaches for malaria. Hum Vaccin (2010) 1.50
Prolonged antigen presentation is required for optimal CD8+ T cell responses against malaria liver stage parasites. PLoS Pathog (2010) 1.39
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The Puf-family RNA-binding protein Puf2 controls sporozoite conversion to liver stages in the malaria parasite. PLoS One (2011) 1.01
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Why functional pre-erythrocytic and bloodstage malaria vaccines fail: a meta-analysis of fully protective immunizations and novel immunological model. PLoS One (2010) 0.87
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A genetically attenuated parasite vaccine does not require liver stage persistence to elicit sterile protective immunity against sporozoite-induced malaria in mice. J Infect Dis (2010) 0.78
Chloroquine neither eliminates liver stage parasites nor delays their development in a murine Chemoprophylaxis Vaccination model. Front Microbiol (2015) 0.78
Induction of antimalaria immunity by pyrimethamine prophylaxis during exposure to sporozoites is curtailed by parasite resistance. Antimicrob Agents Chemother (2011) 0.78
Complex Minigene Library Vaccination for Discovery of Pre-Erythrocytic Plasmodium T Cell Antigens. PLoS One (2016) 0.75
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Genetically modified Plasmodium parasites as a protective experimental malaria vaccine. Nature (2004) 4.35
High efficiency transfection of Plasmodium berghei facilitates novel selection procedures. Mol Biochem Parasitol (2005) 3.95
Randomized controlled trial of a traditional preparation of Artemisia annua L. (Annual Wormwood) in the treatment of malaria. Trans R Soc Trop Med Hyg (2004) 3.52
Plasmodium liver stage developmental arrest by depletion of a protein at the parasite-host interface. Proc Natl Acad Sci U S A (2005) 3.06
Short report: Piloting paperless data entry for clinical research in Africa. Am J Trop Med Hyg (2005) 2.85
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Dihydroartemisinin-piperaquine and artemether-lumefantrine for treating uncomplicated malaria in African children: a randomised, non-inferiority trial. PLoS One (2009) 2.43
In vitro activities of piperaquine, lumefantrine, and dihydroartemisinin in Kenyan Plasmodium falciparum isolates and polymorphisms in pfcrt and pfmdr1. Antimicrob Agents Chemother (2009) 2.36
Intravital observation of Plasmodium berghei sporozoite infection of the liver. PLoS Biol (2005) 2.32
Lateral organization of membrane proteins: tetraspanins spin their web. Biochem J (2009) 2.30
Fosmidomycin for malaria. Lancet (2002) 2.03
Plasmodium sporozoite motility is modulated by the turnover of discrete adhesion sites. Cell Host Microbe (2009) 2.01
Chloroquine resistance before and after its withdrawal in Kenya. Malar J (2009) 1.88
Myosin A tail domain interacting protein (MTIP) localizes to the inner membrane complex of Plasmodium sporozoites. J Cell Sci (2003) 1.85
Long-term treatment of intestinal helminths increases mite skin-test reactivity in Gabonese schoolchildren. J Infect Dis (2004) 1.85
Genetically attenuated Plasmodium berghei liver stages induce sterile protracted protection that is mediated by major histocompatibility complex Class I-dependent interferon-gamma-producing CD8+ T cells. J Infect Dis (2007) 1.79
Differential transcriptome profiling identifies Plasmodium genes encoding pre-erythrocytic stage-specific proteins. Mol Microbiol (2004) 1.76
A malarial cysteine protease is necessary for Plasmodium sporozoite egress from oocysts. J Exp Med (2005) 1.71
A sporozoite asparagine-rich protein controls initiation of Plasmodium liver stage development. PLoS Pathog (2008) 1.65
Towards an in vitro model of Plasmodium hypnozoites suitable for drug discovery. PLoS One (2011) 1.60
Assessment of volume depletion in children with malaria. PLoS Med (2004) 1.51
Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine. Am J Trop Med Hyg (2014) 1.51
Genetically attenuated Plasmodium berghei liver stages persist and elicit sterile protection primarily via CD8 T cells. Am J Pathol (2007) 1.51
Fosmidomycin for the treatment of malaria. Parasitol Res (2002) 1.40
Natural immunization against malaria: causal prophylaxis with antibiotics. Sci Transl Med (2010) 1.31
Defining clinical malaria: the specificity and incidence of endpoints from active and passive surveillance of children in rural Kenya. PLoS One (2010) 1.30
Gene disruption of Plasmodium falciparum p52 results in attenuation of malaria liver stage development in cultured primary human hepatocytes. PLoS One (2008) 1.25
The Plasmodium sporozoite journey: a rite of passage. Trends Parasitol (2003) 1.24
Optimal sampling designs for estimation of Plasmodium falciparum clearance rates in patients treated with artemisinin derivatives. Malar J (2013) 1.21
Multistep adhesion of Plasmodium sporozoites. FASEB J (2010) 1.20
Cell biology and immunology of malaria. Immunol Rev (2011) 1.20
Temperature shift and host cell contact up-regulate sporozoite expression of Plasmodium falciparum genes involved in hepatocyte infection. PLoS Pathog (2008) 1.19
Artesunate-clindamycin versus quinine-clindamycin in the treatment of Plasmodium falciparum malaria: a randomized controlled trial. Clin Infect Dis (2005) 1.18
Unusual properties of Plasmodium falciparum actin: new insights into microfilament dynamics of apicomplexan parasites. FEBS Lett (2005) 1.18
Regulation of apicomplexan microfilament dynamics by a minimal set of actin-binding proteins. Traffic (2006) 1.18
A Plasmodium actin-depolymerizing factor that binds exclusively to actin monomers. Mol Biol Cell (2005) 1.16
In vitro activities of 25 quinolones and fluoroquinolones against liver and blood stage Plasmodium spp. Antimicrob Agents Chemother (2003) 1.16
In vitro activities of quinine and other antimalarials and pfnhe polymorphisms in Plasmodium isolates from Kenya. Antimicrob Agents Chemother (2010) 1.15
Clinical and parasitological characteristics of puerperal malaria. J Infect Dis (2005) 1.15
Population genetic analysis of Plasmodium falciparum parasites using a customized Illumina GoldenGate genotyping assay. PLoS One (2011) 1.13
High diversity of West African bat malaria parasites and a tight link with rodent Plasmodium taxa. Proc Natl Acad Sci U S A (2013) 1.11
Antibody responses to Plasmodium falciparum merozoite surface protein-1 and efficacy of amodiaquine in Gabonese children with P. falciparum malaria. J Infect Dis (2003) 1.11
The N-terminal domain of Plasmodium falciparum circumsporozoite protein represents a target of protective immunity. Vaccine (2008) 1.11
Interactions of the malaria parasite and its mammalian host. Curr Opin Microbiol (2008) 1.11
Arrested oocyst maturation in Plasmodium parasites lacking type II NADH:ubiquinone dehydrogenase. J Biol Chem (2011) 1.09
New approach for high-throughput screening of drug activity on Plasmodium liver stages. Antimicrob Agents Chemother (2006) 1.08
In vivo and in vitro efficacy of amodiaquine against Plasmodium falciparum in an area of continued use of 4-aminoquinolines in East Africa. J Infect Dis (2009) 1.08
Critical role for a stage-specific actin in male exflagellation of the malaria parasite. Cell Microbiol (2011) 1.06
Hepatocyte permissiveness to Plasmodium infection is conveyed by a short and structurally conserved region of the CD81 large extracellular domain. PLoS Pathog (2008) 1.05
The N'-terminal domain of glyceraldehyde-3-phosphate dehydrogenase of the apicomplexan Plasmodium falciparum mediates GTPase Rab2-dependent recruitment to membranes. Biol Chem (2003) 1.05
Structural basis for parasite-specific functions of the divergent profilin of Plasmodium falciparum. Structure (2008) 1.05
Expansion of experimental genetics approaches for Plasmodium berghei with versatile transfection vectors. Mol Biochem Parasitol (2012) 1.05
NF135.C10: a new Plasmodium falciparum clone for controlled human malaria infections. J Infect Dis (2012) 1.04
Fosmidomycin uptake into Plasmodium and Babesia-infected erythrocytes is facilitated by parasite-induced new permeability pathways. PLoS One (2011) 1.04
In vitro activity of antifolate and polymorphism in dihydrofolate reductase of Plasmodium falciparum isolates from the Kenyan coast: emergence of parasites with Ile-164-Leu mutation. Antimicrob Agents Chemother (2009) 1.04
Caspase-1 activation of interleukin-1β (IL-1β) and IL-18 is dispensable for induction of experimental cerebral malaria. Infect Immun (2011) 1.02
The Puf-family RNA-binding protein Puf2 controls sporozoite conversion to liver stages in the malaria parasite. PLoS One (2011) 1.01
Two putative protein export regulators promote Plasmodium blood stage development in vivo. Mol Biochem Parasitol (2013) 1.00
The Plasmodium serine-type SERA proteases display distinct expression patterns and non-essential in vivo roles during life cycle progression of the malaria parasite. Cell Microbiol (2009) 1.00
Critical role for heat shock protein 20 (HSP20) in migration of malarial sporozoites. J Biol Chem (2011) 1.00
The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data. BMC Med (2015) 0.99
Pharmacokinetic and pharmacodynamic characteristics of a new pediatric formulation of artemether-lumefantrine in African children with uncomplicated Plasmodium falciparum malaria. Antimicrob Agents Chemother (2011) 0.98
Flow cytometry-assisted rapid isolation of recombinant Plasmodium berghei parasites exemplified by functional analysis of aquaglyceroporin. Int J Parasitol (2012) 0.98
Functional characterization of a redundant Plasmodium TRAP family invasin, TRAP-like protein, by aldolase binding and a genetic complementation test. Eukaryot Cell (2008) 0.98
Transcription status of vaccine candidate genes of Plasmodium falciparum during the hepatic phase of its life cycle. Parasitol Res (2004) 0.97
Inactivation of a Plasmodium apicoplast protein attenuates formation of liver merozoites. Mol Microbiol (2011) 0.97
PlasmoView: a web-based resource to visualise global Plasmodium falciparum genomic variation. J Infect Dis (2013) 0.97
Unique apicomplexan IMC sub-compartment proteins are early markers for apical polarity in the malaria parasite. Biol Open (2013) 0.96
Naturally acquired immune responses against Plasmodium falciparum sporozoites and liver infection. Int J Parasitol (2012) 0.96
Role for the Plasmodium sporozoite-specific transmembrane protein S6 in parasite motility and efficient malaria transmission. Cell Microbiol (2008) 0.96
The exported Plasmodium berghei protein IBIS1 delineates membranous structures in infected red blood cells. Mol Microbiol (2012) 0.95
Structure-activity-based design of a synthetic malaria peptide eliciting sporozoite inhibitory antibodies in a virosomal formulation. Chem Biol (2007) 0.94
Plasmodium motility: actin not actin' like actin. Trends Parasitol (2006) 0.93
Delayed parasite elimination in human infections treated with clindamycin parallels 'delayed death' of Plasmodium falciparum in vitro. Int J Parasitol (2006) 0.93
Molecular make-up of the Plasmodium parasitophorous vacuolar membrane. Int J Med Microbiol (2012) 0.93
Actin regulation in the malaria parasite. Eur J Cell Biol (2011) 0.93
Strong impact of CD4+ Foxp3+ regulatory T cells and limited effect of T cell-derived IL-10 on pathogen clearance during Plasmodium yoelii infection. J Immunol (2012) 0.93
Loss-of-function analyses defines vital and redundant functions of the Plasmodium rhomboid protease family. Mol Microbiol (2013) 0.92
Triggers and tricks of Plasmodium sexual development. Curr Opin Microbiol (2007) 0.92
Comparative efficacy of pre-erythrocytic whole organism vaccine strategies against the malaria parasite. Vaccine (2011) 0.91
Environmental constraints guide migration of malaria parasites during transmission. PLoS Pathog (2011) 0.91
Identification of targets of CD8⁺ T cell responses to malaria liver stages by genome-wide epitope profiling. PLoS Pathog (2013) 0.91
Structure and function of a G-actin sequestering protein with a vital role in malaria oocyst development inside the mosquito vector. J Biol Chem (2010) 0.91
A constitutive pan-hexose permease for the Plasmodium life cycle and transgenic models for screening of antimalarial sugar analogs. FASEB J (2010) 0.91
Baseline data of parasite clearance in patients with falciparum malaria treated with an artemisinin derivative: an individual patient data meta-analysis. Malar J (2015) 0.91
Assessment of antibody protection against malaria sporozoites must be done by mosquito injection of sporozoites. Am J Pathol (2007) 0.90
Vital role for the Plasmodium actin capping protein (CP) beta-subunit in motility of malaria sporozoites. Mol Microbiol (2009) 0.90
A virosomal malaria peptide vaccine elicits a long-lasting sporozoite-inhibitory antibody response in a phase 1a clinical trial. PLoS One (2007) 0.89
Malaria Sporozoites Traverse Host Cells within Transient Vacuoles. Cell Host Microbe (2015) 0.87
Post-transcriptional silencing of UIS4 in Plasmodium berghei sporozoites is important for host switch. Mol Microbiol (2014) 0.87