Published in J Infect Dis on February 18, 2004
The 'hygiene hypothesis' for autoimmune and allergic diseases: an update. Clin Exp Immunol (2010) 3.17
Helminth infections and host immune regulation. Clin Microbiol Rev (2012) 2.02
Asthma in Hispanics. Am J Respir Crit Care Med (2005) 1.84
Long-term periodic anthelmintic treatments are associated with increased allergen skin reactivity. Clin Exp Allergy (2010) 1.73
Interactions between helminth parasites and allergy. Curr Opin Allergy Clin Immunol (2009) 1.58
Impairment of protective immunity to blood-stage malaria by concurrent nematode infection. Infect Immun (2005) 1.47
Helminth-host immunological interactions: prevention and control of immune-mediated diseases. Ann N Y Acad Sci (2012) 1.47
Effect of Antihelminthic Treatment on Vaccine Immunogenicity to a Seasonal Influenza Vaccine in Primary School Children in Gabon: A Randomized Placebo-Controlled Trial. PLoS Negl Trop Dis (2015) 1.39
Experimental hookworm infection: a randomized placebo-controlled trial in asthma. Clin Exp Allergy (2009) 1.32
Chronic helminth infections protect against allergic diseases by active regulatory processes. Curr Allergy Asthma Rep (2010) 1.15
Anthelminthic treatment during pregnancy is associated with increased risk of infantile eczema: randomised-controlled trial results. Pediatr Allergy Immunol (2011) 1.12
Impact of early life exposures to geohelminth infections on the development of vaccine immunity, allergic sensitization, and allergic inflammatory diseases in children living in tropical Ecuador: the ECUAVIDA birth cohort study. BMC Infect Dis (2011) 1.11
Suppression of inflammatory immune responses in celiac disease by experimental hookworm infection. PLoS One (2011) 1.10
Epidemiology of concomitant infection due to Loa loa and Mansonella perstans in Gabon. PLoS Negl Trop Dis (2011) 1.08
Immunity against helminths: interactions with the host and the intercurrent infections. J Biomed Biotechnol (2010) 1.08
Paradoxical helminthiasis and giardiasis in Cape Town, South Africa: epidemiology and control. Afr Health Sci (2005) 1.04
Repeated treatments with albendazole enhance Th2 responses to Ascaris Lumbricoides, but not to aeroallergens, in children from rural communities in the Tropics. J Infect Dis (2008) 1.02
Suppression of type 2 immunity and allergic airway inflammation by secreted products of the helminth Heligmosomoides polygyrus. Eur J Immunol (2012) 1.00
Ascaris suum-derived products suppress mucosal allergic inflammation in an interleukin-10-independent manner via interference with dendritic cell function. Infect Immun (2006) 0.99
Helminths in the hygiene hypothesis: sooner or later? Clin Exp Immunol (2014) 0.99
Human helminth therapy to treat inflammatory disorders - where do we stand? BMC Immunol (2015) 0.99
Modulation of specific and allergy-related immune responses by helminths. J Biomed Biotechnol (2011) 0.98
Skin prick test reactivity to common allergens among women in Entebbe, Uganda. Trans R Soc Trop Med Hyg (2008) 0.98
Functional impairment of human myeloid dendritic cells during Schistosoma haematobium infection. PLoS Negl Trop Dis (2010) 0.97
Role of helminths in regulating mucosal inflammation. Springer Semin Immunopathol (2005) 0.97
Randomized, controlled, assessor-blind clinical trial to assess the efficacy of single- versus repeated-dose albendazole to treat ascaris lumbricoides, trichuris trichiura, and hookworm infection. Antimicrob Agents Chemother (2014) 0.96
Lower expression of TLR2 and SOCS-3 is associated with Schistosoma haematobium infection and with lower risk for allergic reactivity in children living in a rural area in Ghana. PLoS Negl Trop Dis (2008) 0.96
A longitudinal study of allergy and intestinal helminth infections in semi urban and rural areas of Flores, Indonesia (ImmunoSPIN Study). BMC Infect Dis (2011) 0.96
Integrated analysis of innate, Th1, Th2, Th17, and regulatory cytokines identifies changes in immune polarisation following treatment of human schistosomiasis. J Infect Dis (2012) 0.95
Interactions between parasites and microbial communities in the human gut. Front Cell Infect Microbiol (2012) 0.95
Schistosome infection intensity is inversely related to auto-reactive antibody levels. PLoS One (2011) 0.94
Unraveling the Hygiene Hypothesis of helminthes and autoimmunity: origins, pathophysiology, and clinical applications. BMC Med (2015) 0.93
Translational mini-review series on Toll-like receptors: Toll-like receptor ligands as novel pharmaceuticals for allergic disorders. Clin Exp Immunol (2007) 0.92
Oesophagostomum dentatum extract modulates T cell-dependent immune responses to bystander antigens and prevents the development of allergy in mice. PLoS One (2013) 0.91
Regulation of the host immune system by helminth parasites. J Allergy Clin Immunol (2016) 0.91
Treatment with anthelminthics during pregnancy: what gains and what risks for the mother and child? Parasitology (2011) 0.86
Helminths: Immunoregulation and Inflammatory Diseases-Which Side Are Trichinella spp. and Toxocara spp. on? J Parasitol Res (2013) 0.85
A study on the immunological basis of the dissociation between type I-hypersensitivity skin reactions to Blomia tropicalis antigens and serum anti-B. tropicalis IgE antibodies. BMC Immunol (2011) 0.84
Crude extracts of Caenorhabditis elegans suppress airway inflammation in a murine model of allergic asthma. PLoS One (2012) 0.84
Schistosoma haematobium infection levels determine the effect of praziquantel treatment on anti-schistosome and anti-mite antibodies. Parasite Immunol (2012) 0.83
Cohort Profile: The Ecuador Life (ECUAVIDA) study in Esmeraldas Province, Ecuador. Int J Epidemiol (2014) 0.83
The Lake Victoria Island Intervention Study on Worms and Allergy-related diseases (LaVIISWA): study protocol for a randomised controlled trial. Trials (2015) 0.82
Impact of Anti-Retroviral Treatment and Cotrimoxazole Prophylaxis on Helminth Infections in HIV-Infected Patients in Lambaréné, Gabon. PLoS Negl Trop Dis (2015) 0.81
Paradoxical helminthiasis and giardiasis in Cape Town, South Africa: epidemiology and control. Afr Health Sci (2005) 0.81
Schistosoma mansoni-mediated suppression of allergic airway inflammation requires patency and Foxp3+ Treg cells. PLoS Negl Trop Dis (2013) 0.81
Relationship between the rate of giardiasis and knowledge and practice of prevention in primary school children in south of Tehran. Parasitol Res (2008) 0.81
Helminths and the microbiota: parts of the hygiene hypothesis. Parasite Immunol (2015) 0.81
The Influence of IgE on Cultured Human Mast Cells. Allergy Asthma Immunol Res (2013) 0.78
Effects of maternal geohelminth infections on allergy in early childhood. J Allergy Clin Immunol (2015) 0.78
The Role of Helminth Infection and Environment in the Development of Allergy: A Prospective Study of Newly-Arrived Ethiopian Immigrants in Israel. PLoS Negl Trop Dis (2016) 0.76
Helminths are positively associated with atopy and wheeze in Ugandan fishing communities: results from a cross-sectional survey. Allergy (2016) 0.76
Immunological consequences of antihelminthic treatment in preschool children exposed to urogenital schistosome infection. J Trop Med (2013) 0.76
Human schistosome infection and allergic sensitisation. J Parasitol Res (2012) 0.75
Environmental factors influencing multiple sclerosis in Latin America. Mult Scler J Exp Transl Clin (2017) 0.75
Cellular cytokine and chemokine responses to parasite antigens and fungus and mite allergens in children co-infected with helminthes and protozoa parasites. J Inflamm (Lond) (2015) 0.75
Worming our way closer to the clinic. Int J Parasitol Drugs Drug Resist (2012) 0.75
Immune Profile of Honduran Schoolchildren with Intestinal Parasites: The Skewed Response against Geohelminths. J Parasitol Res (2016) 0.75
Effective anthelmintic therapy of residents living in endemic area of high prevalence for Hookworm and Schistosoma mansoni infections enhances the levels of allergy risk factor anti-Der p1 IgE. Results Immunol (2013) 0.75
The Multibiome: The Intestinal Ecosystem's Influence on Immune Homeostasis, Health, and Disease. EBioMedicine (2016) 0.75
Allergy and worms: let's bring back old friends? Wien Med Wochenschr (2014) 0.75
Helminths in the gastrointestinal tract as modulators of immunity and pathology. Am J Physiol Gastrointest Liver Physiol (2017) 0.75
Tropical medicine at the University of Tübingen. Wien Klin Wochenschr (2010) 0.75
Parasites and asthma. Parasitol Res (2017) 0.75
Opening a Can of Worms: Leprosy Reactions and Complicit Soil-Transmitted Helminths. EBioMedicine (2017) 0.75
Spread of artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med (2014) 11.87
Immune regulation by helminth parasites: cellular and molecular mechanisms. Nat Rev Immunol (2003) 5.97
Successes and failures in the control of infectious diseases in Brazil: social and environmental context, policies, interventions, and research needs. Lancet (2011) 5.69
Allergy, parasites, and the hygiene hypothesis. Science (2002) 5.01
Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing. Nature (2012) 4.37
Protection by BCG vaccine against tuberculosis: a systematic review of randomized controlled trials. Clin Infect Dis (2013) 4.26
Longitudinal study of infectious intestinal disease in the UK (IID2 study): incidence in the community and presenting to general practice. Gut (2011) 3.71
Randomized controlled trial of a traditional preparation of Artemisia annua L. (Annual Wormwood) in the treatment of malaria. Trans R Soc Trop Med Hyg (2004) 3.52
Safety and immunogenicity of a novel multivalent OspA vaccine against Lyme borreliosis in healthy adults: a double-blind, randomised, dose-escalation phase 1/2 trial. Lancet Infect Dis (2013) 3.46
Short report: Piloting paperless data entry for clinical research in Africa. Am J Trop Med Hyg (2005) 2.85
Gut microbiota composition and development of atopic manifestations in infancy: the KOALA Birth Cohort Study. Gut (2006) 2.85
Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin. J Allergy Clin Immunol (2005) 2.70
Placental malaria increases malaria risk in the first 30 months of life. Clin Infect Dis (2008) 2.69
A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates toll-like receptor 2 and affects immune polarization. J Biol Chem (2002) 2.61
Amplification of Plasmodium falciparum multidrug resistance gene 1 in isolates from Gabon. J Infect Dis (2005) 2.58
Effect of revaccination with BCG in early childhood on mortality: randomised trial in Guinea-Bissau. BMJ (2010) 2.52
Dihydroartemisinin-piperaquine and artemether-lumefantrine for treating uncomplicated malaria in African children: a randomised, non-inferiority trial. PLoS One (2009) 2.43
Regulation of pathogenesis and immunity in helminth infections. J Exp Med (2009) 2.39
Chronic helminth infections induce immunomodulation: consequences and mechanisms. Immunobiology (2007) 2.37
In vitro activities of piperaquine, lumefantrine, and dihydroartemisinin in Kenyan Plasmodium falciparum isolates and polymorphisms in pfcrt and pfmdr1. Antimicrob Agents Chemother (2009) 2.36
Severe falciparum malaria in Gabonese children: clinical and laboratory features. Malar J (2005) 2.35
Prevalence of major comorbidities in subjects with COPD and incidence of myocardial infarction and stroke: a comprehensive analysis using data from primary care. Thorax (2010) 2.26
Effect of albendazole treatments on the prevalence of atopy in children living in communities endemic for geohelminth parasites: a cluster-randomised trial. Lancet (2006) 2.25
Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses. J Exp Med (2009) 2.24
Validation of the diagnosis of autism in general practitioner records. BMC Public Health (2004) 2.22
Vitamin A supplementation and BCG vaccination at birth in low birthweight neonates: two by two factorial randomised controlled trial. BMJ (2010) 2.18
Microbial compounds selectively induce Th1 cell-promoting or Th2 cell-promoting dendritic cells in vitro with diverse th cell-polarizing signals. J Immunol (2002) 2.16
Effectiveness and cost-effectiveness of first BCG vaccination against tuberculosis in school-age children without previous tuberculin test (BCG-REVAC trial): a cluster-randomised trial. Lancet Infect Dis (2011) 2.08
Fosmidomycin for malaria. Lancet (2002) 2.03
MMR vaccination and pervasive developmental disorders: a case-control study. Lancet (2004) 2.02
Outbreak of aseptic meningitis and mumps after mass vaccination with MMR vaccine using the Leningrad-Zagreb mumps strain. Vaccine (2002) 2.02
High prevalence of asymptomatic Plasmodium falciparum infection in Gabonese adults. Am J Trop Med Hyg (2007) 1.99
Intermittent preventive treatment against malaria in infants in Gabon--a randomized, double-blind, placebo-controlled trial. J Infect Dis (2007) 1.99
Effect of 50,000 IU vitamin A given with BCG vaccine on mortality in infants in Guinea-Bissau: randomised placebo controlled trial. BMJ (2008) 1.91
Microscopic and sub-microscopic Plasmodium falciparum infection, but not inflammation caused by infection, is associated with low birth weight. Am J Trop Med Hyg (2006) 1.88
Chloroquine resistance before and after its withdrawal in Kenya. Malar J (2009) 1.88
Community incidence of norovirus-associated infectious intestinal disease in England: improved estimates using viral load for norovirus diagnosis. Am J Epidemiol (2010) 1.86
The study of infectious intestinal disease in England: what risk factors for presentation to general practice tell us about potential for selection bias in case-control studies of reported cases of diarrhoea. Int J Epidemiol (2003) 1.83
Local activation of the tissue factor-factor VIIa pathway in patients with pneumonia and the effect of inhibition of this pathway in murine pneumococcal pneumonia. Crit Care Med (2006) 1.82
Impact of the hepatitis B virus genotype and genotype mixtures on the course of liver disease in Vietnam. Hepatology (2006) 1.82
Is it better to be rich in a poor area or poor in a rich area? A multilevel analysis of a case-control study of social determinants of tuberculosis. Int J Epidemiol (2009) 1.75
Vaccine-like immunity against malaria by repeated causal-prophylactic treatment of liver-stage Plasmodium parasites. J Infect Dis (2009) 1.70
Fixed-dose pyronaridine-artesunate combination for treatment of uncomplicated falciparum malaria in pediatric patients in Gabon. J Infect Dis (2008) 1.70
Influenza in Africa. PLoS Med (2009) 1.68
Import and spread of Panton-Valentine Leukocidin-positive Staphylococcus aureus through nasal carriage and skin infections in travelers returning from the tropics and subtropics. Clin Infect Dis (2011) 1.67
Allergenicity assessment of genetically modified crops--what makes sense? Nat Biotechnol (2008) 1.67
A guide to modern statistical analysis of immunological data. BMC Immunol (2007) 1.66
Internet-based tapering of oral corticosteroids in severe asthma: a pragmatic randomised controlled trial. Thorax (2011) 1.66
Reduced risk of atopy among school-age children infected with geohelminth parasites in a rural area of the tropics. J Allergy Clin Immunol (2003) 1.65
Chronic intestinal helminth infections are associated with immune hyporesponsiveness and induction of a regulatory network. Infect Immun (2010) 1.65
Evaluation of regression methods when immunological measurements are constrained by detection limits. BMC Immunol (2008) 1.64
Increased specific T cell cytokine responses in patients with active pulmonary tuberculosis from Central Africa. Microbes Infect (2005) 1.63
Depressed natural killer cell cytotoxicity against Plasmodium falciparum-infected erythrocytes during first pregnancies. Clin Infect Dis (2004) 1.61
Antiinflammatory effects of salmeterol after inhalation of lipopolysaccharide by healthy volunteers. Am J Respir Crit Care Med (2005) 1.60
Intramuscular bioavailability and clinical efficacy of artesunate in gabonese children with severe malaria. Antimicrob Agents Chemother (2002) 1.59
Increased prevalence of intestinal helminth infection during pregnancy in a Sub-Saharan African community. Wien Klin Wochenschr (2007) 1.58
Antithrombin inhibits bronchoalveolar activation of coagulation and limits lung injury during Streptococcus pneumoniae pneumonia in rats. Crit Care Med (2008) 1.58
Does treatment of intestinal helminth infections influence malaria? Background and methodology of a longitudinal study of clinical, parasitological and immunological parameters in Nangapanda, Flores, Indonesia (ImmunoSPIN Study). BMC Infect Dis (2010) 1.57
Impact of increasing consultation fees on malaria in Africa. Wien Klin Wochenschr (2004) 1.56
Activation of coagulation and inhibition of fibrinolysis in the human lung on bronchial instillation of lipoteichoic acid and lipopolysaccharide. Crit Care Med (2009) 1.55
History and perspectives of medical research at the Albert Schweitzer Hospital in Lambaréné, Gabon. Wien Klin Wochenschr (2007) 1.52
Assessment of volume depletion in children with malaria. PLoS Med (2004) 1.51
Matrix metalloproteinases and their tissue inhibitors (TIMPs) in Plasmodium falciparum malaria: serum levels of TIMP-1 are associated with disease severity. J Infect Dis (2008) 1.51
Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine. Am J Trop Med Hyg (2014) 1.51
Risk factors and immunological pathways for asthma and other allergic diseases in children: background and methodology of a longitudinal study in a large urban center in Northeastern Brazil (Salvador-SCAALA study). BMC Pulm Med (2006) 1.49
Design of the leprosy component of the Brazilian BCG revaccination trial for assessing BCG effectiveness against leprosy in school children. Int J Lepr Other Mycobact Dis (2004) 1.48
Guillain-Barré syndrome and preceding infection with campylobacter, influenza and Epstein-Barr virus in the general practice research database. PLoS One (2007) 1.47
Socio-economic status is inversely related to bed net use in Gabon. Malar J (2008) 1.46
Regulatory T cells in human geohelminth infection suppress immune responses to BCG and Plasmodium falciparum. Eur J Immunol (2010) 1.45
Adolescence as risk factor for adverse pregnancy outcome in Central Africa--a cross-sectional study. PLoS One (2010) 1.43
Allergies and diabetes as risk factors for dengue hemorrhagic fever: results of a case control study. PLoS Negl Trop Dis (2010) 1.41
Effectiveness of rifaximin in prevention of diarrhoea in individuals travelling to south and southeast Asia: a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Infect Dis (2013) 1.41
Changes in causes of acute gastroenteritis in the United Kingdom over 15 years: microbiologic findings from 2 prospective, population-based studies of infectious intestinal disease. Clin Infect Dis (2012) 1.41
Fosmidomycin for the treatment of malaria. Parasitol Res (2002) 1.40
Evidence of decline of malaria in the general hospital of Libreville, Gabon from 2000 to 2008. Malar J (2009) 1.40
Reduced cord blood immune effector-cell responsiveness mediated by CD4+ cells induced in utero as a consequence of placental Plasmodium falciparum infection. J Infect Dis (2005) 1.40
Age-related changes in hookworm infection, anaemia and iron deficiency in an area of high Necator americanus hookworm transmission in south-eastern Brazil. Trans R Soc Trop Med Hyg (2006) 1.40
Plasmodium falciparum activates endogenous Cl(-) channels of human erythrocytes by membrane oxidation. EMBO J (2002) 1.40
Methods for determining disease burden and calibrating national surveillance data in the United Kingdom: the second study of infectious intestinal disease in the community (IID2 study). BMC Med Res Methodol (2010) 1.38
Differential regulation of beta-chemokines in children with Plasmodium falciparum malaria. Infect Immun (2005) 1.37
Incidence of Guillain-Barré syndrome among patients with Campylobacter infection: a general practice research database study. J Infect Dis (2006) 1.36
Clindamycin as an antimalarial drug: review of clinical trials. Antimicrob Agents Chemother (2002) 1.36
Elevated nitric oxide production in children with malarial anemia: hemozoin-induced nitric oxide synthase type 2 transcripts and nitric oxide in blood mononuclear cells. Infect Immun (2004) 1.35
Fosmidomycin plus clindamycin for treatment of pediatric patients aged 1 to 14 years with Plasmodium falciparum malaria. Antimicrob Agents Chemother (2006) 1.35
Fosmidomycin-clindamycin for Plasmodium falciparum Infections in African children. J Infect Dis (2004) 1.35
Fosmidomycin-clindamycin for the treatment of Plasmodium falciparum malaria. J Infect Dis (2004) 1.34
Malaria in pregnancy before and after the implementation of a national IPTp program in Gabon. Am J Trop Med Hyg (2007) 1.34