Published in Curr Med Chem on January 01, 2009
TGFbeta/TNF(alpha)-mediated epithelial-mesenchymal transition generates breast cancer stem cells with a claudin-low phenotype. Cancer Res (2011) 1.65
In situ identification of putative cancer stem cells by multiplexing ALDH1, CD44, and cytokeratin identifies breast cancer patients with poor prognosis. Am J Pathol (2010) 1.62
Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/progenitor cells. Oncogene (2012) 1.49
AXL induces epithelial-to-mesenchymal transition and regulates the function of breast cancer stem cells. Oncogene (2013) 1.27
Aldehyde dehydrogenase 1, a potential marker for cancer stem cells in human sarcoma. PLoS One (2012) 1.19
Inhibition of the autophagic flux by salinomycin in breast cancer stem-like/progenitor cells interferes with their maintenance. Autophagy (2013) 1.15
Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cells. Nat Commun (2015) 1.09
Expression of the Cancer Stem Cell Markers CD44 and CD133 in Colorectal Cancer: An Immunohistochemical Staining Analysis. Ann Coloproctol (2015) 1.01
OCT4 Expression Enhances Features of Cancer Stem Cells in a Mouse Model of Breast Cancer. Lab Anim Res (2011) 1.00
Inhibition of autophagy as a new means of improving chemotherapy efficiency in high-LC3B triple-negative breast cancers. Autophagy (2014) 0.99
Perspectives on cancer stem cells in osteosarcoma. Cancer Lett (2012) 0.97
Cancer stem cells, epithelial-mesenchymal transition, and drug resistance in high-grade ovarian serous carcinoma. Hum Pathol (2013) 0.95
Enhanced expression of stem cell markers and drug resistance in sphere-forming non-small cell lung cancer cells. Int J Clin Exp Pathol (2015) 0.90
Cancer stem cells in colorectal cancer from pathogenesis to therapy: controversies and perspectives. World J Gastroenterol (2014) 0.90
HSP90 inhibitor 17-AAG selectively eradicates lymphoma stem cells. Cancer Res (2012) 0.89
Targeting lung cancer stem-like cells with TRAIL gene armed oncolytic adenovirus. J Cell Mol Med (2015) 0.89
Novel micelle formulation of curcumin for enhancing antitumor activity and inhibiting colorectal cancer stem cells. Int J Nanomedicine (2012) 0.87
Expressions and clinical significances of CD133 protein and CD133 mRNA in primary lesion of gastric adenocacinoma. J Exp Clin Cancer Res (2010) 0.87
Effect of the WWOX gene on the regulation of the cell cycle and apoptosis in human ovarian cancer stem cells. Mol Med Rep (2015) 0.86
Pinellia pedatisecta agglutinin targets drug resistant K562/ADR leukemia cells through binding with sarcolemmal membrane associated protein and enhancing macrophage phagocytosis. PLoS One (2013) 0.85
Cancer stem cell theory: therapeutic implications for nanomedicine. Int J Nanomedicine (2013) 0.84
Ectopic expression of the WWOX gene suppresses stemness of human ovarian cancer stem cells. Oncol Lett (2015) 0.84
Synthetic, non-saccharide, glycosaminoglycan mimetics selectively target colon cancer stem cells. ACS Chem Biol (2014) 0.83
Small-molecule inhibitors of DNA damage-repair pathways: an approach to overcome tumor resistance to alkylating anticancer drugs. Future Med Chem (2012) 0.83
Advances in the proteomic discovery of novel therapeutic targets in cancer. Drug Des Devel Ther (2013) 0.82
Synthesis and characterization of DNA minor groove binding alkylating agents. Chem Res Toxicol (2012) 0.82
Targeting CSCs in tumor microenvironment: the potential role of ROS-associated miRNAs in tumor aggressiveness. Curr Stem Cell Res Ther (2014) 0.81
Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo. Oncotarget (2015) 0.80
Variable NF-κB pathway responses in colon cancer cells treated with chemotherapeutic drugs. BMC Cancer (2014) 0.80
Inhibitor of DNA-binding 4 contributes to the maintenance and expansion of cancer stem cells in 4T1 mouse mammary cancer cell line. Lab Anim Res (2011) 0.80
Targeting breast cancer stem cells in triple-negative breast cancer using a combination of LBH589 and salinomycin. Breast Cancer Res Treat (2015) 0.79
Overcoming chemo/radio-resistance of pancreatic cancer by inhibiting STAT3 signaling. Oncotarget (2016) 0.78
Inhibition of C-terminal binding protein attenuates transcription factor 4 signaling to selectively target colon cancer stem cells. Cell Cycle (2014) 0.77
Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cells. Oncotarget (2016) 0.77
Systemic approaches identify a garlic-derived chemical, Z-ajoene, as a glioblastoma multiforme cancer stem cell-specific targeting agent. Mol Cells (2014) 0.76
The biological complexity of colorectal cancer: insights into biomarkers for early detection and personalized care. Therap Adv Gastroenterol (2016) 0.75
A rational approach for cancer stem-like cell isolation and characterization using CD44 and prominin-1(CD133) as selection markers. Oncotarget (2016) 0.75
The functional curcumin liposomes induce apoptosis in C6 glioblastoma cells and C6 glioblastoma stem cells in vitro and in animals. Int J Nanomedicine (2017) 0.75
Adult neurogenesis and glial oncogenesis: when the process fails. Biomed Res Int (2014) 0.75
Characteristics of primary side population cervical cancer cells. Oncol Lett (2017) 0.75
Up-regulation of glycolysis promotes the stemness and EMT phenotypes in gemcitabine-resistant pancreatic cancer cells. J Cell Mol Med (2017) 0.75
Thirty-five-year follow-up analysis of clinical and pathologic outcomes of thymoma surgery. Ann Thorac Surg (2010) 2.08
Persistent air leak after pulmonary resection: the water-valve "foam" problem. Ann Thorac Surg (2004) 2.03
Systems medicine and integrated care to combat chronic noncommunicable diseases. Genome Med (2011) 1.78
Alpha7-nicotinic acetylcholine receptors affect growth regulation of human mesothelioma cells: role of mitogen-activated protein kinase pathway. Cancer Res (2004) 1.77
Retracted Inhibition of nonneuronal alpha7-nicotinic receptor for lung cancer treatment. Am J Respir Crit Care Med (2009) 1.74
Enhancement of the antitumor properties of interleukin-2 by its targeted delivery to the tumor blood vessel extracellular matrix. Blood (2002) 1.66
IL-21 induces tumor rejection by specific CTL and IFN-gamma-dependent CXC chemokines in syngeneic mice. J Immunol (2004) 1.58
Single-centre 40-year results of redo operation for recurrent thymomas. Eur J Cardiothorac Surg (2011) 1.52
Jaw transformation with gain of symmetry after Dlx5/Dlx6 inactivation: mirror of the past? Genesis (2002) 1.47
Long-term results after treatment for recurrent thymoma: a multicenter analysis. J Thorac Oncol (2014) 1.47
Endovascular treatment of pulmonary sequestration in adults using Amplatzer® vascular plugs. Interact Cardiovasc Thorac Surg (2010) 1.46
Induction therapy followed by surgery for T3-T4/N0 non-small cell lung cancer: long-term results. Ann Thorac Surg (2012) 1.46
Intrathoracic gastric perforation: a late complication of an unknown postpartum recurrent hiatal hernia. Interact Cardiovasc Thorac Surg (2012) 1.39
Interleukin-21 receptor (IL-21R) is up-regulated by CD40 triggering and mediates proapoptotic signals in chronic lymphocytic leukemia B cells. Blood (2006) 1.38
Mouse model of split hand/foot malformation type I. Genesis (2002) 1.37
Adding ipsilateral V20 and V30 to conventional dosimetric constraints predicts radiation pneumonitis in stage IIIA-B NSCLC treated with combined-modality therapy. Int J Radiat Oncol Biol Phys (2010) 1.25
The ALCAM shedding by the metalloprotease ADAM17/TACE is involved in motility of ovarian carcinoma cells. Mol Cancer Res (2007) 1.25
Immunoprevention of HER-2/neu transgenic mammary carcinoma through an interleukin 12-engineered allogeneic cell vaccine. Cancer Res (2004) 1.25
Oxidative stress-related biomarkers in autism: systematic review and meta-analyses. Free Radic Biol Med (2012) 1.24
Membrane-bound and soluble IL-15/IL-15Ralpha complexes display differential signaling and functions on human hematopoietic progenitors. Blood (2005) 1.22
Post-operative respiratory rehabilitation after lung resection for non-small cell lung cancer. Lung Cancer (2007) 1.21
The Dlx5 homeobox gene is essential for vestibular morphogenesis in the mouse embryo through a BMP4-mediated pathway. Dev Biol (2002) 1.19
Subcellular localization of activated leukocyte cell adhesion molecule is a molecular predictor of survival in ovarian carcinoma patients. Clin Cancer Res (2008) 1.16
EGFR-targeted therapy for non-small cell lung cancer: focus on EGFR oncogenic mutation. Int J Med Sci (2013) 1.14
The opposite effects of IL-15 and IL-21 on CLL B cells correlate with differential activation of the JAK/STAT and ERK1/2 pathways. Blood (2007) 1.12
Gene expression signature for angiogenic and nonangiogenic non-small-cell lung cancer. Oncogene (2005) 1.11
Role of common-gamma chain cytokines in NK cell development and function: perspectives for immunotherapy. J Biomed Biotechnol (2011) 1.09
Adjuvant radiotherapy in non-small cell lung cancer with pathological stage I: definitive results of a phase III randomized trial. Radiother Oncol (2002) 1.09
Msx1 and Dlx5 act independently in development of craniofacial skeleton, but converge on the regulation of Bmp signaling in palate formation. Mech Dev (2005) 1.09
Pre-operative pulmonary rehabilitation and surgery for lung cancer. Lung Cancer (2007) 1.08
N2 nodal involvement in multiple primary lung cancer: really an exclusion criterion? Chest (2013) 1.07
Bronchial carcinoid tumors causing Cushing's syndrome: an insidious disease. Ann Thorac Surg (2013) 1.07
Typical bronchial carcinoid tumors: focus on surgical management. Ann Thorac Surg (2012) 1.07
Exocytosis of azurophil and arginase 1-containing granules by activated polymorphonuclear neutrophils is required to inhibit T lymphocyte proliferation. J Leukoc Biol (2011) 1.07
The redox state of the lung cancer microenvironment depends on the levels of thioredoxin expressed by tumor cells and affects tumor progression and response to prooxidants. Int J Cancer (2008) 1.07
Antimetastatic activity of a preventive cancer vaccine. Cancer Res (2007) 1.07
Malignant solitary fibrous tumors of the pleura: retrospective review of a multicenter series. J Thorac Oncol (2012) 1.07
Surgery and Survival of Patients with Diagnosis of Malignant Pleural Mesothelioma. J Thorac Oncol (2015) 1.07
Is it time to validate the prognostic role of F-18-FDG PET/CT scan in thymic epithelial tumors? Ann Nucl Med (2014) 1.06
Differentiation therapy: targeting human renal cancer stem cells with interleukin 15. J Natl Cancer Inst (2011) 1.05
Targeting tumor-related immunosuppression for cancer immunotherapy. Endocr Metab Immune Disord Drug Targets (2006) 1.03
Direct inhibition of hexokinase activity by metformin at least partially impairs glucose metabolism and tumor growth in experimental breast cancer. Cell Cycle (2013) 1.03
Ferritin contributes to melanoma progression by modulating cell growth and sensitivity to oxidative stress. Clin Cancer Res (2005) 1.02
Microdrainage via open technique in severe subcutaneous emphysema. Chest (2003) 1.02
Expression and methylation of CASP8 in neuroblastoma: identification of a promoter region. Nat Med (2002) 1.02
Tumor necrosis factor receptor-associated protein 1(TRAP1) regulates genes involved in cell cycle and metastases. Cancer Lett (2010) 1.01
Mda-9/syntenin is expressed in uveal melanoma and correlates with metastatic progression. PLoS One (2012) 1.01
CIITA-induced MHC class II expression in mammary adenocarcinoma leads to a Th1 polarization of the tumor microenvironment, tumor rejection, and specific antitumor memory. Clin Cancer Res (2006) 1.01
The cholinergic system and cancer. Semin Cancer Biol (2007) 1.00
Successful early treatment of Boerhaave's syndrome by endoscopic placement of a temporary self-expandable plastic stent without fluoroscopy. Gastrointest Endosc (2003) 1.00
The Dlx5 homeodomain gene is essential for olfactory development and connectivity in the mouse. Mol Cell Neurosci (2003) 1.00
Chest wall giant lipoma with a thirty-year history. Interact Cardiovasc Thorac Surg (2012) 0.99
Tumor rejection by gene transfer of the MHC class II transactivator in murine mammary adenocarcinoma cells. Eur J Immunol (2003) 0.98
Natural agents targeting the alpha7-nicotinic-receptor in NSCLC: a promising prospective in anti-cancer drug development. Int J Cancer (2008) 0.98
An interaction between hepatocyte growth factor and its receptor (c-MET) prolongs the survival of chronic lymphocytic leukemic cells through STAT3 phosphorylation: a potential role of mesenchymal cells in the disease. Haematologica (2011) 0.97
alpha7-Nicotinic receptor antagonists at the beginning of a clinical era for NSCLC and Mesothelioma? Drug Discov Today (2009) 0.97
CD25+ regulatory T cell depletion augments immunotherapy of micrometastases by an IL-21-secreting cellular vaccine. J Immunol (2006) 0.97
Phase I trial of weekly gemcitabine and concurrent radiotherapy in patients with inoperable non-small-cell lung cancer. J Clin Oncol (2002) 0.97
Gene expression analysis of immune-mediated arrest of tumorigenesis in a transgenic mouse model of HER-2/neu-positive basal-like mammary carcinoma. Am J Pathol (2005) 0.97
Nicotine, lung and cancer. Anticancer Agents Med Chem (2007) 0.97
Gliadin-mediated proliferation and innate immune activation in celiac disease are due to alterations in vesicular trafficking. PLoS One (2011) 0.96
Nicotine: specific role in angiogenesis, proliferation and apoptosis. Crit Rev Toxicol (2011) 0.96
Metformin impairs glucose consumption and survival in Calu-1 cells by direct inhibition of hexokinase-II. Sci Rep (2013) 0.96
IL-8 induces exocytosis of arginase 1 by neutrophil polymorphonuclears in nonsmall cell lung cancer. Int J Cancer (2009) 0.96
Concentrative uptake of cyclic ADP-ribose generated by BST-1+ stroma stimulates proliferation of human hematopoietic progenitors. J Biol Chem (2004) 0.96
PET/CT assessment of neuroendocrine tumors of the lung with special emphasis on bronchial carcinoids. Tumour Biol (2014) 0.95
Transient depletion of CD4(+) T cells augments IL-21-based immunotherapy of disseminated neuroblastoma in syngeneic mice. Int J Cancer (2010) 0.95
Inexpensive anatomical trainer for bronchoscopy. Interact Cardiovasc Thorac Surg (2007) 0.95
Post-esophagectomy anastomotic leaks. The role of the anastomotic location. Ann Ital Chir (2013) 0.95
Internalization and recycling of ALCAM/CD166 detected by a fully human single-chain recombinant antibody. J Cell Sci (2005) 0.94
Role of CXCL13-CXCR5 crosstalk between malignant neuroblastoma cells and Schwannian stromal cells in neuroblastic tumors. Mol Cancer Res (2011) 0.94
Caspase-8 gene expression in neuroblastoma. Ann N Y Acad Sci (2004) 0.93
Role of the non-neuronal human cholinergic system in lung cancer and mesothelioma: possibility of new therapeutic strategies. Curr Med Chem Anticancer Agents (2004) 0.92
Genetic susceptibility to malignant pleural mesothelioma and other asbestos-associated diseases. Mutat Res (2008) 0.91
Inhibition of mammary carcinoma development in HER-2/neu transgenic mice through induction of autoimmunity by xenogeneic DNA vaccination. Cancer Res (2005) 0.91
Pulmonary metastases from parachordoma. Ann Thorac Surg (2009) 0.91
Pulmonary metastases: can accurate radiological evaluation avoid thoracotomic approach? Eur J Cardiothorac Surg (2002) 0.91
Interferon gamma-induced human guanylate binding protein 1 inhibits mammary tumor growth in mice. Mol Med (2010) 0.90
Rationale and clinical benefits of an intensive long-term pulmonary rehabilitation program after oesophagectomy: preliminary report. Multidiscip Respir Med (2012) 0.90