Published in J Lipid Res on May 20, 2009
A conserved SREBP-1/phosphatidylcholine feedback circuit regulates lipogenesis in metazoans. Cell (2011) 2.75
Endoplasmic reticulum stress and the unfolded protein response in nonalcoholic fatty liver disease. Antioxid Redox Signal (2011) 1.02
Links between lipid homeostasis, organelle morphodynamics and protein trafficking in eukaryotic and plant secretory pathways. Plant Cell Rep (2010) 0.93
Phospholipid synthesis participates in the regulation of diacylglycerol required for membrane trafficking at the Golgi complex. J Biol Chem (2011) 0.86
The essential neutral sphingomyelinase is involved in the trafficking of the variant surface glycoprotein in the bloodstream form of Trypanosoma brucei. Mol Microbiol (2010) 0.85
Role for Lipid Droplet Biogenesis and Microlipophagy in Adaptation to Lipid Imbalance in Yeast. Dev Cell (2015) 0.79
Phenomenology based multiscale models as tools to understand cell membrane and organelle morphologies. Adv Planar Lipid Bilayers Liposomes (2016) 0.77
Englerin A induces an acute inflammatory response and reveals lipid metabolism and ER stress as targetable vulnerabilities in renal cell carcinoma. PLoS One (2017) 0.75
Regulation of Stress Responses and Translational Control by Coronavirus. Viruses (2016) 0.75
A rapid method of total lipid extraction and purification. Can J Biochem Physiol (1959) 173.74
A trip to the ER: coping with stress. Trends Cell Biol (2004) 7.67
Lipid droplets: a unified view of a dynamic organelle. Nat Rev Mol Cell Biol (2006) 6.85
Protein kinase C and lipid signaling for sustained cellular responses. FASEB J (1995) 6.80
Kinetic analysis of secretory protein traffic and characterization of golgi to plasma membrane transport intermediates in living cells. J Cell Biol (1998) 5.14
Exit of newly synthesized membrane proteins from the trans cisterna of the Golgi complex to the plasma membrane. J Cell Biol (1985) 4.93
Functional genomic screen reveals genes involved in lipid-droplet formation and utilization. Nature (2008) 4.70
Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death. J Lipid Res (2006) 3.64
The regulation and cellular functions of phosphatidylcholine hydrolysis. Biochem J (1990) 3.44
Phosphatidylcholine breakdown and signal transduction. Biochim Biophys Acta (1994) 3.42
Role of diacylglycerol in PKD recruitment to the TGN and protein transport to the plasma membrane. Science (2001) 3.39
Stereological analysis of the guinea pig pancreas. I. Analytical model and quantitative description of nonstimulated pancreatic exocrine cells. J Cell Biol (1974) 2.70
Diffusion of green fluorescent protein in the aqueous-phase lumen of endoplasmic reticulum. Biophys J (1999) 2.59
ER-phagy: selective autophagy of the endoplasmic reticulum. Autophagy (2007) 2.21
Cellular responses to excess phospholipid. J Biol Chem (1999) 1.99
A phosphatidylinositol transfer protein controls the phosphatidylcholine content of yeast Golgi membranes. J Cell Biol (1994) 1.90
Maintenance of the diacylglycerol level in the Golgi apparatus by the Nir2 protein is critical for Golgi secretory function. Nat Cell Biol (2005) 1.71
Cell cycle regulation of membrane phospholipid metabolism. J Biol Chem (1996) 1.61
A genetic defect in phosphatidylcholine biosynthesis triggers apoptosis in Chinese hamster ovary cells. J Biol Chem (1996) 1.52
Neuropathy target esterase and its yeast homologue degrade phosphatidylcholine to glycerophosphocholine in living cells. J Biol Chem (2004) 1.51
Autoradiographic detection of animal cell membrane mutants altered in phosphatidylcholine synthesis. Proc Natl Acad Sci U S A (1980) 1.38
CTP:phosphocholine cytidylyltransferase. Biochim Biophys Acta (1997) 1.37
Distribution of CTP:phosphocholine cytidylyltransferase (CCT) isoforms. Identification of a new CCTbeta splice variant. J Biol Chem (1999) 1.26
The Sec14-superfamily and the regulatory interface between phospholipid metabolism and membrane trafficking. Biochim Biophys Acta (2007) 1.24
Inhibition of phosphatidylcholine synthesis induces expression of the endoplasmic reticulum stress and apoptosis-related protein CCAAT/enhancer-binding protein-homologous protein (CHOP/GADD153). Biochem J (2003) 1.22
Thermolabile CDP-choline synthetase in an animal cell mutant defective in lecithin formation. J Biol Chem (1981) 1.20
Regulation of phosphatidylcholine biosynthesis. Prog Lipid Res (1990) 1.19
Apoptosis triggered by 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine is prevented by increased expression of CTP:phosphocholine cytidylyltransferase. J Biol Chem (1998) 1.12
Structure of the membrane binding domain of CTP:phosphocholine cytidylyltransferase. Biochemistry (1996) 1.12
Molecular aspects of membrane fission in the secretory pathway. Cell Mol Life Sci (2002) 1.09
Activity of the phosphatidylcholine biosynthetic pathway modulates the distribution of fatty acids into glycerolipids in proliferating cells. Biochim Biophys Acta (2000) 1.06
Animal cells dependent on exogenous phosphatidylcholine for membrane biogenesis. Proc Natl Acad Sci U S A (1982) 0.99
Regulation of phosphatidylcholine homeostasis by calcium-independent phospholipase A2. Biochim Biophys Acta (1999) 0.98
Comparative toxicity of fatty acids on a macrophage cell line (J774). Clin Sci (Lond) (2006) 0.96
Effects of phorbol ester on phospholipid metabolism. Prog Lipid Res (1990) 0.95
Cytokine secretion requires phosphatidylcholine synthesis. J Cell Biol (2008) 0.94
Expression of wild-type and mutant rat liver CTP: phosphocholine cytidylyltransferase in a cytidylyltransferase-deficient Chinese hamster ovary cell line. Arch Biochem Biophys (1994) 0.87
How cytidylyltransferase uses an amphipathic helix to sense membrane phospholipid composition. Biochem Soc Trans (1998) 0.86
CTP: phosphocholine cytidylyltransferase is both a nuclear and cytoplasmic protein in primary hepatocytes. Eur J Cell Biol (1996) 0.86
Phosphatidylcholine deficiency upregulates enzymes of triacylglycerol metabolism in CHO cells. J Lipid Res (2004) 0.86
Why expression of phosphatidylethanolamine N-methyltransferase does not rescue Chinese hamster ovary cells that have an impaired CDP-choline pathway. J Biol Chem (2000) 0.80
Inhibition of phosphatidylcholine synthesis is not the primary pathway in hexadecylphosphocholine-induced apoptosis. Biochim Biophys Acta (2004) 0.78
Identification of a candidate therapeutic autophagy-inducing peptide. Nature (2013) 3.76
Gene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies. Arthritis Res Ther (2013) 1.57
Mass spectrometric detection of cholesterol oxidation in bovine sperm. Biol Reprod (2011) 1.50
Phosphatidylcholine and cell death. Biochim Biophys Acta (2002) 1.30
Inhibition of phosphatidylcholine synthesis induces expression of the endoplasmic reticulum stress and apoptosis-related protein CCAAT/enhancer-binding protein-homologous protein (CHOP/GADD153). Biochem J (2003) 1.22
Identification and characterization of a novel human plant pathogenesis-related protein that localizes to lipid-enriched microdomains in the Golgi complex. J Cell Sci (2002) 1.18
Involvement of a Golgi-resident GPI-anchored protein in maintenance of the Golgi structure. Mol Biol Cell (2007) 1.09
Lipids in host-pathogen interactions: pathogens exploit the complexity of the host cell lipidome. Prog Lipid Res (2009) 1.07
SCAP is required for timely and proper myelin membrane synthesis. Proc Natl Acad Sci U S A (2009) 1.05
Interactions of influenza A virus with sialic acids present on porcine surfactant protein D. Am J Respir Cell Mol Biol (2003) 1.04
Structural analysis of the human Golgi-associated plant pathogenesis related protein GAPR-1 implicates dimerization as a regulatory mechanism. J Mol Biol (2004) 1.04
Porcine pulmonary collectins show distinct interactions with influenza A viruses: role of the N-linked oligosaccharides in the carbohydrate recognition domain. J Immunol (2003) 1.02
Atherosclerotic lesion progression changes lysophosphatidic acid homeostasis to favor its accumulation. Am J Pathol (2010) 1.01
In vivo profiling and visualization of cellular protein-lipid interactions using bifunctional fatty acids. Angew Chem Int Ed Engl (2013) 1.01
Oleic acid prevents detrimental effects of saturated fatty acids on bovine oocyte developmental competence. Biol Reprod (2011) 1.00
The CDP-ethanolamine pathway and phosphatidylserine decarboxylation generate different phosphatidylethanolamine molecular species. J Biol Chem (2007) 0.99
Intra-Golgi protein transport depends on a cholesterol balance in the lipid membrane. J Biol Chem (2003) 0.97
Phosphatidylinositol-3-phosphate clearance plays a key role in autophagosome completion. Curr Biol (2012) 0.97
Part of membrane-bound Abeta exists in rafts within senile plaques in Tg2576 mouse brain. Neurobiol Aging (2005) 0.95
Binding of GAPR-1 to negatively charged phospholipid membranes: unusual binding characteristics to phosphatidylinositol. Mol Membr Biol (2010) 0.93
Ultrastructural localization of flotillin-1 to cholesterol-rich membrane microdomains, rafts, in rat brain tissue. Brain Res (2003) 0.93
What triggers cell-mediated mineralization? Front Biosci (2007) 0.92
Replacement of retinyl esters by polyunsaturated triacylglycerol species in lipid droplets of hepatic stellate cells during activation. PLoS One (2012) 0.92
Distinct lipid compositions of two types of human prostasomes. Proteomics (2013) 0.91
Cholesterol loss during glutamate-mediated excitotoxicity. EMBO J (2012) 0.91
Targeted metabolomics identifies glucuronides of dietary phytoestrogens as a major class of MRP3 substrates in vivo. Gastroenterology (2009) 0.90
Quantitative proteomic identification of host factors involved in the Salmonella typhimurium infection cycle. Proteomics (2011) 0.90
Oligomeric proteins ultrastructurally localize to cell processes, especially to axon terminals with higher density, but not to lipid rafts in Tg2576 mouse brain. Brain Res (2005) 0.90
Porcine surfactant protein D is N-glycosylated in its carbohydrate recognition domain and is assembled into differently charged oligomers. Am J Respir Cell Mol Biol (2002) 0.89
Interaction of GAPR-1 with lipid bilayers is regulated by alternative homodimerization. Biochim Biophys Acta (2012) 0.87
The yeast acyltransferase Sct1p regulates fatty acid desaturation by competing with the desaturase Ole1p. Mol Biol Cell (2012) 0.87
Identification of host factors involved in coronavirus replication by quantitative proteomics analysis. Proteomics (2010) 0.87
Control of the CDPethanolamine pathway in mammalian cells: effect of CTP:phosphoethanolamine cytidylyltransferase overexpression and the amount of intracellular diacylglycerol. Biochem J (2004) 0.87
Metabolipidomics: profiling metabolism of glycerophospholipid species by stable isotopic precursors and tandem mass spectrometry. Anal Biochem (2006) 0.84
Bovine cumulus cells protect maturing oocytes from increased fatty acid levels by massive intracellular lipid storage. Biol Reprod (2013) 0.82
Structural requirements for palmitoylation of surfactant protein C precursor. Biochem J (2002) 0.80
Iron ions derived from the nitric oxide donor sodium nitroprusside inhibit mineralization. Eur J Pharmacol (2006) 0.79
Involvement of bicarbonate-induced radical signaling in oxysterol formation and sterol depletion of capacitating mammalian sperm during in vitro fertilization. Biol Reprod (2013) 0.78
Inhibition of phosphatidylcholine synthesis is not the primary pathway in hexadecylphosphocholine-induced apoptosis. Biochim Biophys Acta (2004) 0.78
Soluble factors released by ATDC5 cells affect the formation of calcium phosphate crystals. Biochim Biophys Acta (2007) 0.78
Hexadecylphosphocholine causes rapid cell death in canine mammary tumour cells. Eur J Pharmacol (2004) 0.78
Surfactant protein D binding to terminal alpha1-3-linked fucose residues and to Schistosoma mansoni. Am J Respir Cell Mol Biol (2004) 0.78
Differential effect of brefeldin A on the palmitoylation of surfactant protein C proprotein mutants. Biochem Biophys Res Commun (2002) 0.77
Crystallization of a Golgi-associated PR-1-related protein (GAPR-1) that localizes to lipid-enriched microdomains. Acta Crystallogr D Biol Crystallogr (2004) 0.77
The transmembrane domain of surfactant protein C precursor determines the morphology of the induced membrane compartment in CHO cells. Eur J Cell Biol (2003) 0.77
Effect of ceramides on phospholipid biosynthesis and its implication for apoptosis. Subcell Biochem (2002) 0.76
Quantitative proteomic identification of host factors involved in the Salmonella typhimurium infection cycle. Methods Mol Biol (2015) 0.75