Published in BMJ on May 28, 2009
An independent external validation and evaluation of QRISK cardiovascular risk prediction: a prospective open cohort study. BMJ (2009) 5.45
An independent and external validation of QRISK2 cardiovascular disease risk score: a prospective open cohort study. BMJ (2010) 4.46
Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): explanation and elaboration. PLoS Med (2012) 3.62
Predictive accuracy of the Liverpool Lung Project risk model for stratifying patients for computed tomography screening for lung cancer: a case-control and cohort validation study. Ann Intern Med (2012) 3.45
Prognosis Research Strategy (PROGRESS) 3: prognostic model research. PLoS Med (2013) 3.13
Risk models and scores for type 2 diabetes: systematic review. BMJ (2011) 3.02
Prediction models for cardiovascular disease risk in the general population: systematic review. BMJ (2016) 2.81
Prediction of critical illness during out-of-hospital emergency care. JAMA (2010) 2.60
Developing risk prediction models for type 2 diabetes: a systematic review of methodology and reporting. BMC Med (2011) 2.44
Safe exclusion of pulmonary embolism using the Wells rule and qualitative D-dimer testing in primary care: prospective cohort study. BMJ (2012) 2.38
Reporting and methods in clinical prediction research: a systematic review. PLoS Med (2012) 2.26
Individualized medical decision making: necessary, achievable, but not yet attainable. Arch Intern Med (2010) 2.01
Activation of the STAT3 signaling pathway is associated with poor survival in diffuse large B-cell lymphoma treated with R-CHOP. J Clin Oncol (2013) 1.91
External validation of a Cox prognostic model: principles and methods. BMC Med Res Methodol (2013) 1.88
Clinical risk prediction for pre-eclampsia in nulliparous women: development of model in international prospective cohort. BMJ (2011) 1.88
Reporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaboration. BMC Med (2012) 1.85
A single institution's 26-year experience with nonfunctional pancreatic neuroendocrine tumors: a validation of current staging systems and a new prognostic nomogram. Ann Surg (2014) 1.76
Correcting for optimistic prediction in small data sets. Am J Epidemiol (2014) 1.69
Reporting methods in studies developing prognostic models in cancer: a review. BMC Med (2010) 1.68
Effect of changes over time in the performance of a customized SAPS-II model on the quality of care assessment. Intensive Care Med (2011) 1.65
Reporting performance of prognostic models in cancer: a review. BMC Med (2010) 1.65
External validation of multivariable prediction models: a systematic review of methodological conduct and reporting. BMC Med Res Methodol (2014) 1.57
Simple ultrasound rules to distinguish between benign and malignant adnexal masses before surgery: prospective validation by IOTA group. BMJ (2010) 1.55
Prediction models for risk of developing type 2 diabetes: systematic literature search and independent external validation study. BMJ (2012) 1.52
Integrating Palliative Care Into the Care of Neurocritically Ill Patients: A Report From the Improving Palliative Care in the ICU Project Advisory Board and the Center to Advance Palliative Care. Crit Care Med (2015) 1.50
Comparison of three different tools for prediction of seminal vesicle invasion at radical prostatectomy. Eur Urol (2012) 1.50
Development of prediction tools for diarrhea and rash in breast cancer patients receiving lapatinib in combination with capecitabine. Breast Cancer Res Treat (2014) 1.49
The central role of prognosis in clinical decision making. JAMA (2012) 1.38
Critical appraisal and data extraction for systematic reviews of prediction modelling studies: the CHARMS checklist. PLoS Med (2014) 1.35
Sample size considerations for the external validation of a multivariable prognostic model: a resampling study. Stat Med (2015) 1.35
Support of personalized medicine through risk-stratified treatment recommendations - an environmental scan of clinical practice guidelines. BMC Med (2013) 1.27
Reappraising the concept of massive transfusion in trauma. Crit Care (2010) 1.27
Prediction of dementia in primary care patients. PLoS One (2011) 1.25
Predicting risk of osteoporotic and hip fracture in the United Kingdom: prospective independent and external validation of QFractureScores. BMJ (2011) 1.25
Dynamic data during hypotensive episode improves mortality predictions among patients with sepsis and hypotension. Crit Care Med (2013) 1.24
Prediction of mortality in very premature infants: a systematic review of prediction models. PLoS One (2011) 1.20
Systems biology approaches to new vaccine development. Curr Opin Immunol (2011) 1.17
Research methods for subgrouping low back pain. BMC Med Res Methodol (2010) 1.16
EuroSCORE II and the importance of a local model, InsCor and the future SP-SCORE. Rev Bras Cir Cardiovasc (2014) 1.15
Translation and discriminative validation of the STarT Back Screening Tool into Danish. Eur Spine J (2011) 1.13
Multidimensional prognostic indices for use in COPD patient care. A systematic review. Respir Res (2011) 1.13
Risk prediction models for chemotherapy-induced nausea and vomiting: almost ready for prime time? Support Care Cancer (2014) 1.12
External validation of the UK Prospective Diabetes Study (UKPDS) risk engine in patients with type 2 diabetes. Diabetologia (2010) 1.11
Comment on Kanis et al.: Pitfalls in the external validation of FRAX. Osteoporos Int (2012) 1.09
Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD): the TRIPOD Statement. BMC Med (2015) 1.07
Evaluation of genetic tests for susceptibility to common complex diseases: why, when and how? Hum Genet (2009) 1.03
Large-scale international validation of the ADO index in subjects with COPD: an individual subject data analysis of 10 cohorts. BMJ Open (2012) 1.03
Big data in organ transplantation: registries and administrative claims. Am J Transplant (2014) 0.99
Polytomous diagnosis of ovarian tumors as benign, borderline, primary invasive or metastatic: development and validation of standard and kernel-based risk prediction models. BMC Med Res Methodol (2010) 0.99
Biomarkers in Barrett's esophagus and esophageal adenocarcinoma: predictors of progression and prognosis. World J Gastroenterol (2010) 0.98
Validity of British Thoracic Society guidance (the CRB-65 rule) for predicting the severity of pneumonia in general practice: systematic review and meta-analysis. Br J Gen Pract (2010) 0.97
Prognostic models for the early care of trauma patients: a systematic review. Scand J Trauma Resusc Emerg Med (2011) 0.97
The effects of data sources, cohort selection, and outcome definition on a predictive model of risk of thirty-day hospital readmissions. J Biomed Inform (2014) 0.97
External validation of clinical prediction models using big datasets from e-health records or IPD meta-analysis: opportunities and challenges. BMJ (2016) 0.96
What clinical signs best identify severe illness in young infants aged 0-59 days in developing countries? A systematic review. Arch Dis Child (2011) 0.96
Prediction of poor outcome in patients with acute liver failure-systematic review of prediction models. PLoS One (2012) 0.95
Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. Eur J Epidemiol (2011) 0.94
The TARGET cohort study protocol: a prospective primary care cohort study to derive and validate a clinical prediction rule to improve the targeting of antibiotics in children with respiratory tract illnesses. BMC Health Serv Res (2013) 0.94
Independent external validation of nomograms for predicting risk of low-trauma fracture and hip fracture. CMAJ (2010) 0.92
Making ICU prognostication patient centered: is there a role for dynamic information? Crit Care Med (2013) 0.92
Prediction of cardiovascular risk using Framingham, ASSIGN and QRISK2: how well do they predict individual rather than population risk? PLoS One (2014) 0.92
Clinical prediction models for bronchopulmonary dysplasia: a systematic review and external validation study. BMC Pediatr (2013) 0.92
Pain trajectory groups in persons with, or at high risk of, knee osteoarthritis: findings from the Knee Clinical Assessment Study and the Osteoarthritis Initiative. Osteoarthritis Cartilage (2014) 0.91
The utility of liver function tests for mortality prediction within one year in primary care using the algorithm for liver function investigations (ALFI). PLoS One (2012) 0.91
Development and validation of the Surgical Outcome Risk Tool (SORT). Br J Surg (2014) 0.91
Predictive risk stratification model: a progressive cluster-randomised trial in chronic conditions management (PRISMATIC) research protocol. Trials (2013) 0.90
Bridging the etiologic and prognostic outlooks in individualized assessment of absolute risk of an illness: application in lung cancer. Eur J Epidemiol (2016) 0.90
Risk factors for adverse prognosis and death in American visceral leishmaniasis: a meta-analysis. PLoS Negl Trop Dis (2014) 0.89
The predictive and external validity of the STarT Back Tool in Danish primary care. Eur Spine J (2013) 0.89
Developing and validating risk prediction models in an individual participant data meta-analysis. BMC Med Res Methodol (2014) 0.89
Patients' & healthcare professionals' values regarding true- & false-positive diagnosis when colorectal cancer screening by CT colonography: discrete choice experiment. PLoS One (2013) 0.89
Multivariate meta-analysis of individual participant data helped externally validate the performance and implementation of a prediction model. J Clin Epidemiol (2015) 0.89
Self-rated health and long-term prognosis of depression. Ann Fam Med (2014) 0.88
Long noncoding RNAs as novel predictors of survival in human cancer: a systematic review and meta-analysis. Mol Cancer (2016) 0.87
External validation of the KORA S4/F4 prediction models for the risk of developing type 2 diabetes in older adults: the PREVEND study. Eur J Epidemiol (2012) 0.87
Diagnostic prediction models for suspected pulmonary embolism: systematic review and independent external validation in primary care. BMJ (2015) 0.86
A primer on predictive models. Clin Transl Gastroenterol (2014) 0.86
Predicting the risk of hyperkalemia in patients with chronic kidney disease starting lisinopril. Pharmacoepidemiol Drug Saf (2010) 0.85
Comparison of measures of comorbidity for predicting disability 12-months post-injury. BMC Health Serv Res (2013) 0.85
Predicting the cumulative risk of death during hospitalization by modeling weekend, weekday and diurnal mortality risks. BMC Health Serv Res (2014) 0.84
Adaptation of clinical prediction models for application in local settings. Med Decis Making (2012) 0.84
Predictors of shoulder pain and disability index (SPADI) and work status after 1 year in patients with subacromial shoulder pain. BMC Musculoskelet Disord (2010) 0.84
DEVELOPMENT AND VALIDATION OF A NOVEL TOOL TO PREDICT HOSPITAL READMISSION RISK AMONG PATIENTS WITH DIABETES. Endocr Pract (2016) 0.84
Modeling the risk of esophageal squamous cell carcinoma and squamous dysplasia in a high risk area in Iran. Arch Iran Med (2012) 0.84
Algorithms for the prediction of retinopathy of prematurity based on postnatal weight gain. Clin Perinatol (2013) 0.83
Predicting outcomes after blunt chest wall trauma: development and external validation of a new prognostic model. Crit Care (2014) 0.83
Assessment of disease activity in patients with rheumatoid arthritis using optical spectral transmission measurements, a non-invasive imaging technique. Ann Rheum Dis (2015) 0.83
What is the impact of chronic kidney disease stage and cardiovascular disease on the annual cost of hospital care in moderate-to-severe kidney disease? BMC Nephrol (2015) 0.83
Performance of InsCor and three international scores in cardiac surgery at Santa Casa de Marília. Rev Bras Cir Cardiovasc (2015) 0.83
Novel prediction score including pre- and intraoperative parameters best predicts acute kidney injury after liver surgery. World J Surg (2013) 0.83
Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD): the TRIPOD statement. The TRIPOD Group. Circulation (2015) 0.83
Special considerations in prognostic research in cancer involving genetic polymorphisms. BMC Med (2013) 0.83
Prediction of asymptomatic carotid artery stenosis in the general population: identification of high-risk groups. Stroke (2014) 0.83
A simple score for estimating the long-term risk of fracture in patients with multiple sclerosis. Neurology (2012) 0.83
One-Year Mortality in Older Patients with Cancer: Development and External Validation of an MNA-Based Prognostic Score. PLoS One (2016) 0.83
Norwegian survival prediction model in trauma: modelling effects of anatomic injury, acute physiology, age, and co-morbidity. Acta Anaesthesiol Scand (2014) 0.82
Key variables for interpreting 99mTc-mercaptoacetyltriglycine diuretic scans: development and validation of a predictive model. AJR Am J Roentgenol (2011) 0.82
Multiple imputation for missing data in epidemiological and clinical research: potential and pitfalls. BMJ (2009) 19.23
Multiple imputation using chained equations: Issues and guidance for practice. Stat Med (2010) 17.36
Review: a gentle introduction to imputation of missing values. J Clin Epidemiol (2006) 8.87
Effectiveness of antipsychotic drugs in first-episode schizophrenia and schizophreniform disorder: an open randomised clinical trial. Lancet (2008) 6.24
Effect of intracranial pressure monitoring and targeted intensive care on functional outcome after severe head injury. Crit Care Med (2005) 5.85
Expansion of the prognostic assessment of patients with chronic obstructive pulmonary disease: the updated BODE index and the ADO index. Lancet (2009) 5.51
The design of simulation studies in medical statistics. Stat Med (2006) 5.30
The cost of dichotomising continuous variables. BMJ (2006) 5.12
Cognitive outcome after off-pump and on-pump coronary artery bypass graft surgery: a randomized trial. JAMA (2002) 5.06
Prognosis and prognostic research: what, why, and how? BMJ (2009) 4.46
Prognosis and prognostic research: application and impact of prognostic models in clinical practice. BMJ (2009) 4.38
Prognosis and prognostic research: Developing a prognostic model. BMJ (2009) 4.38
Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis (TRIPOD): the TRIPOD statement. Ann Intern Med (2015) 4.32
Imputing missing covariate values for the Cox model. Stat Med (2009) 4.31
Development and validation of MIX: comprehensive free software for meta-analysis of causal research data. BMC Med Res Methodol (2006) 3.67
Imputation of missing values is superior to complete case analysis and the missing-indicator method in multivariable diagnostic research: a clinical example. J Clin Epidemiol (2006) 3.28
The Wells rule does not adequately rule out deep venous thrombosis in primary care patients. Ann Intern Med (2005) 3.21
Prognosis Research Strategy (PROGRESS) 3: prognostic model research. PLoS Med (2013) 3.13
Effectiveness of electronic fetal monitoring with additional ST analysis in vertex singleton pregnancies at >36 weeks of gestation: an individual participant data metaanalysis. Am J Obstet Gynecol (2013) 3.10
Risk prediction models: II. External validation, model updating, and impact assessment. Heart (2012) 3.05
Dealing with missing outcome data in randomized trials and observational studies. Am J Epidemiol (2011) 3.03
Immortal time bias in critical care research: application of time-varying Cox regression for observational cohort studies. Crit Care Med (2009) 2.96
Urine neutrophil gelatinase-associated lipocalin moderately predicts acute kidney injury in critically ill adults. J Am Soc Nephrol (2009) 2.77
Risk prediction models: I. Development, internal validation, and assessing the incremental value of a new (bio)marker. Heart (2012) 2.76
Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis (TRIPOD): explanation and elaboration. Ann Intern Med (2015) 2.71
How should variable selection be performed with multiply imputed data? Stat Med (2008) 2.65
Clinical decision rules for excluding pulmonary embolism: a meta-analysis. Ann Intern Med (2011) 2.57
Selection of important variables and determination of functional form for continuous predictors in multivariable model building. Stat Med (2007) 2.46
Combined anatomical and clinical factors for the long-term risk stratification of patients undergoing percutaneous coronary intervention: the Logistic Clinical SYNTAX score. Eur Heart J (2012) 2.43
Meta-analysis of MR imaging in the diagnosis of breast lesions. Radiology (2007) 2.43
Safe exclusion of pulmonary embolism using the Wells rule and qualitative D-dimer testing in primary care: prospective cohort study. BMJ (2012) 2.38
Missing covariate data in medical research: to impute is better than to ignore. J Clin Epidemiol (2010) 2.37
Comparing the diagnostic performance of 2 clinical decision rules to rule out deep vein thrombosis in primary care patients. Ann Fam Med (2011) 2.34
A comparison of imputation techniques for handling missing predictor values in a risk model with a binary outcome. Stat Methods Med Res (2007) 2.31
Prognosis research strategy (PROGRESS) 1: a framework for researching clinical outcomes. BMJ (2013) 2.31
Incidence and predictors of short- and long-term complications in pacemaker therapy: the FOLLOWPACE study. Heart Rhythm (2011) 2.29
Internal and external validation of predictive models: a simulation study of bias and precision in small samples. J Clin Epidemiol (2003) 2.28
Prognostic model for survival in patients with metastatic renal cell carcinoma: results from the international kidney cancer working group. Clin Cancer Res (2011) 2.27
Development and validation of a prognostic model for survival time data: application to prognosis of HIV positive patients treated with antiretroviral therapy. Stat Med (2004) 2.26
Reporting and methods in clinical prediction research: a systematic review. PLoS Med (2012) 2.26
Development and validation of a prediction model with missing predictor data: a practical approach. J Clin Epidemiol (2009) 2.24
Prognosis Research Strategy (PROGRESS) 2: prognostic factor research. PLoS Med (2013) 2.23
Safely ruling out deep venous thrombosis in primary care. Ann Intern Med (2009) 2.16
The effect of outpatient preoperative evaluation of hospital inpatients on cancellation of surgery and length of hospital stay. Anesth Analg (2002) 2.16
Combining estimates of interest in prognostic modelling studies after multiple imputation: current practice and guidelines. BMC Med Res Methodol (2009) 2.12
Cerebral hemodynamic responses to blood pressure manipulation in severely head-injured patients in the presence or absence of intracranial hypertension. Anesth Analg (2004) 2.10
Speeding up the evaluation of new agents in cancer. J Natl Cancer Inst (2008) 2.08
Incidence of intraoperative hypotension as a function of the chosen definition: literature definitions applied to a retrospective cohort using automated data collection. Anesthesiology (2007) 2.05
Comparison of techniques for handling missing covariate data within prognostic modelling studies: a simulation study. BMC Med Res Methodol (2010) 2.05
Predictive factors for postherpetic neuralgia. Clin J Pain (2013) 2.03
External validity of risk models: Use of benchmark values to disentangle a case-mix effect from incorrect coefficients. Am J Epidemiol (2010) 2.03
Accuracy of the Wells clinical prediction rule for pulmonary embolism in older ambulatory adults. J Am Geriatr Soc (2014) 1.98
The PINE study of epidural steroids and local anaesthetics to prevent postherpetic neuralgia: a randomised controlled trial. Lancet (2006) 1.95
Intraoperative hypotension and 1-year mortality after noncardiac surgery. Anesthesiology (2009) 1.85
Issues in applying multi-arm multi-stage methodology to a clinical trial in prostate cancer: the MRC STAMPEDE trial. Trials (2009) 1.81
Improvements in risk stratification for the occurrence of cardiovascular disease by imaging subclinical atherosclerosis: a systematic review. Heart (2011) 1.80
Simvastatin for cognitive deficits and behavioural problems in patients with neurofibromatosis type 1 (NF1-SIMCODA): a randomised, placebo-controlled trial. Lancet Neurol (2013) 1.74
Limited value of patient history and physical examination in diagnosing deep vein thrombosis in primary care. Fam Pract (2005) 1.73
Prognostic model for HIV-1 disease progression in patients starting antiretroviral therapy was validated using independent data. J Clin Epidemiol (2005) 1.72
Prognosis research strategy (PROGRESS) 4: stratified medicine research. BMJ (2013) 1.71
Correcting for optimistic prediction in small data sets. Am J Epidemiol (2014) 1.69
Fast-track anesthesia and cardiac surgery: a retrospective cohort study of 7989 patients. Anesth Analg (2009) 1.68
Reporting methods in studies developing prognostic models in cancer: a review. BMC Med (2010) 1.68
Cardiotocography plus ST analysis of fetal electrocardiogram compared with cardiotocography only for intrapartum monitoring: a randomized controlled trial. Obstet Gynecol (2010) 1.68
Reporting performance of prognostic models in cancer: a review. BMC Med (2010) 1.65
Is the clinical risk score for patients with colorectal liver metastases still useable in the era of effective neoadjuvant chemotherapy? Ann Surg Oncol (2011) 1.63
The diagnostic value of history and physical examination for COPD in suspected or known cases: a systematic review. Fam Pract (2009) 1.62
Interactions between treatment and continuous covariates: a step toward individualizing therapy. J Clin Oncol (2008) 1.62
Bias in sensitivity and specificity caused by data-driven selection of optimal cutoff values: mechanisms, magnitude, and solutions. Clin Chem (2008) 1.58
Should scoring rules be based on odds ratios or regression coefficients? J Clin Epidemiol (2002) 1.58
Hospitalization for respiratory syncytial virus infection in young children: development of a clinical prediction rule. Pediatr Infect Dis J (2006) 1.55
Prediction models for risk of developing type 2 diabetes: systematic literature search and independent external validation study. BMJ (2012) 1.52
Beyond diagnostic accuracy: the clinical utility of diagnostic tests. Clin Chem (2012) 1.49
Autosomal genome-wide scan for coronary artery calcification loci in sibships at high risk for hypertension. Arterioscler Thromb Vasc Biol (2002) 1.46
Children with meningeal signs: predicting who needs empiric antibiotic treatment. Arch Pediatr Adolesc Med (2002) 1.44
FGFR3 mutation analysis in voided urine samples to decrease cystoscopies and cost in nonmuscle invasive bladder cancer surveillance: a comparison of 3 strategies. J Urol (2012) 1.44
Ruling out deep venous thrombosis in primary care. A simple diagnostic algorithm including D-dimer testing. Thromb Haemost (2005) 1.43
Unpredictable bias when using the missing indicator method or complete case analysis for missing confounder values: an empirical example. J Clin Epidemiol (2010) 1.42
Gender as an independent risk factor for herpes zoster: a population-based prospective study. Ann Epidemiol (2006) 1.40
Simplifying a prognostic model: a simulation study based on clinical data. Stat Med (2002) 1.39
Cognitive outcomes five years after not undergoing coronary artery bypass graft surgery. Ann Thorac Surg (2008) 1.39
The Patient Health Questionnaire-9 for detection of major depressive disorder in primary care: consequences of current thresholds in a crosssectional study. BMC Fam Pract (2010) 1.39
Development and validation of an international risk prediction algorithm for episodes of major depression in general practice attendees: the PredictD study. Arch Gen Psychiatry (2008) 1.37