Published in BMJ on June 29, 2009
Detection of Familial Hypercholesterolaemia in Cardiovascular Disease Registry | NCT02778646
CABI: Antibiotic Duration for Complicated Intra-ABdominal Infection (CABI) | NCT03265834
The Supporting Early Learning Study (SEAL) | NCT04107506
A Scaleable Video Coaching Intervention for Opioid-using Mothers | NCT04749771
The Use of a Monitoring Device by General Practitioners During Out-of-hours Care | NCT05222711
SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials. BMJ (2013) 9.01
Prognosis of patients with HIV-1 infection starting antiretroviral therapy in sub-Saharan Africa: a collaborative analysis of scale-up programmes. Lancet (2010) 6.02
Facilitated physical activity as a treatment for depressed adults: randomised controlled trial. BMJ (2012) 5.61
Association between low functional health literacy and mortality in older adults: longitudinal cohort study. BMJ (2012) 4.72
Strategy for intention to treat analysis in randomised trials with missing outcome data. BMJ (2011) 4.12
Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): explanation and elaboration. PLoS Med (2012) 3.62
Risk factors at medical school for subsequent professional misconduct: multicentre retrospective case-control study. BMJ (2010) 3.57
All cause and disease specific mortality in patients with knee or hip osteoarthritis: population based cohort study. BMJ (2011) 3.51
External validation and comparison with other models of the International Metastatic Renal-Cell Carcinoma Database Consortium prognostic model: a population-based study. Lancet Oncol (2013) 3.19
Prognosis Research Strategy (PROGRESS) 3: prognostic model research. PLoS Med (2013) 3.13
New neighborhood grocery store increased awareness of food access but did not alter dietary habits or obesity. Health Aff (Millwood) (2014) 3.05
First trimester fetal growth restriction and cardiovascular risk factors in school age children: population based cohort study. BMJ (2014) 2.97
Retinal vascular caliber and the development of hypertension: a meta-analysis of individual participant data. J Hypertens (2014) 2.83
The REporting of studies Conducted using Observational Routinely-collected health Data (RECORD) Statement. PLoS Med (2015) 2.72
The effect of different alcohol drinking patterns in early to mid pregnancy on the child's intelligence, attention, and executive function. BJOG (2012) 2.71
Outcomes in patients waiting for antiretroviral treatment in the Free State Province, South Africa: prospective linkage study. AIDS (2010) 2.66
Association between depression and functional vision loss in persons 20 years of age or older in the United States, NHANES 2005-2008. JAMA Ophthalmol (2013) 2.52
Impact of managed clinical networks on NHS specialist neonatal services in England: population based study. BMJ (2012) 2.44
Estimates of pandemic influenza vaccine effectiveness in Europe, 2009-2010: results of Influenza Monitoring Vaccine Effectiveness in Europe (I-MOVE) multicentre case-control study. PLoS Med (2011) 2.25
Clinical and social outcomes of adolescent self harm: population based birth cohort study. BMJ (2014) 2.24
Gestational-age-specific reference ranges for blood pressure in pregnancy: findings from a prospective cohort. J Hypertens (2015) 2.14
Increased risk of fragility fractures among HIV infected compared to uninfected male veterans. PLoS One (2011) 2.11
Considerations for observational research using large data sets in radiation oncology. Int J Radiat Oncol Biol Phys (2014) 2.06
Pathways to suicide-related behavior in offspring of mothers with depression: the role of offspring psychopathology. J Am Acad Child Adolesc Psychiatry (2015) 2.01
Self-management of fatigue in rheumatoid arthritis: a randomised controlled trial of group cognitive-behavioural therapy. Ann Rheum Dis (2011) 1.93
Reporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaboration. BMC Med (2012) 1.85
Adjusting mortality for loss to follow-up: analysis of five ART programmes in sub-Saharan Africa. PLoS One (2010) 1.84
Racial/ethnic standards for fetal growth: the NICHD Fetal Growth Studies. Am J Obstet Gynecol (2015) 1.79
Efficacy of standardised manual therapy and home exercise programme for chronic rotator cuff disease: randomised placebo controlled trial. BMJ (2010) 1.73
The efficiency of cardiovascular risk assessment: do the right patients get statin treatment? Heart (2013) 1.73
I-MOVE multi-centre case control study 2010-11: overall and stratified estimates of influenza vaccine effectiveness in Europe. PLoS One (2011) 1.73
Including all individuals is not enough: lessons for intention-to-treat analysis. Clin Trials (2012) 1.71
Weight loss required by the severely obese to achieve clinically important differences in health-related quality of life: two-year prospective cohort study. BMC Med (2014) 1.61
Economic evaluation alongside randomised controlled trials: design, conduct, analysis, and reporting. BMJ (2011) 1.59
External validation of multivariable prediction models: a systematic review of methodological conduct and reporting. BMC Med Res Methodol (2014) 1.57
Associations between the school food environment, student consumption and body mass index of Canadian adolescents. Int J Behav Nutr Phys Act (2014) 1.57
Self-reported quality of life of adolescents with cerebral palsy: a cross-sectional and longitudinal analysis. Lancet (2014) 1.52
The role of health behaviours across the life course in the socioeconomic patterning of all-cause mortality: the west of Scotland twenty-07 prospective cohort study. Ann Behav Med (2014) 1.52
Prediction models for risk of developing type 2 diabetes: systematic literature search and independent external validation study. BMJ (2012) 1.52
Association of Serum Lipids and Coronary Heart Disease in Contemporary Observational Studies. Circulation (2015) 1.51
Predictors of first recurrence of Clostridium difficile infection: implications for initial management. Clin Infect Dis (2012) 1.51
Clinical outcomes of single-visit oral prophylaxis: a practice-based randomised controlled trial. BMC Oral Health (2011) 1.49
Warning Symptoms Are Associated With Survival From Sudden Cardiac Arrest. Ann Intern Med (2016) 1.49
Supporting adherence to antiretroviral therapy with mobile phone reminders: results from a cohort in South India. PLoS One (2012) 1.48
Maternal obesity and gestational weight gain are risk factors for infant death. Obesity (Silver Spring) (2015) 1.48
BRAF mutation status and survival after colorectal cancer diagnosis according to patient and tumor characteristics. Cancer Epidemiol Biomarkers Prev (2012) 1.48
Effects of a mindfulness-based weight loss intervention in adults with obesity: A randomized clinical trial. Obesity (Silver Spring) (2016) 1.46
Patient Prognostic Score and Associations With Survival Improvement Offered by Radiotherapy After Breast-Conserving Surgery for Ductal Carcinoma In Situ: A Population-Based Longitudinal Cohort Study. J Clin Oncol (2016) 1.44
Health promotion in individuals with mental disorders: a cluster preference randomized controlled trial. BMC Public Health (2013) 1.44
Caregiver's education level and child's dental caries in African Americans: a path analytic study. Caries Res (2015) 1.43
Why do those out of work because of sickness or disability have a high mortality risk? Evidence from a Scottish cohort. Eur J Public Health (2012) 1.42
The clinical and cost-effectiveness of brief advice for excessive alcohol consumption among people attending sexual health clinics: a randomised controlled trial. Sex Transm Infect (2014) 1.42
Maternal prepregnancy obesity and cause-specific stillbirth. Am J Clin Nutr (2015) 1.42
Association of dietary factors with presence and severity of tinnitus in a middle-aged UK population. PLoS One (2014) 1.42
KRAS-mutation status in relation to colorectal cancer survival: the joint impact of correlated tumour markers. Br J Cancer (2013) 1.41
Smoking, Smoking Cessation, and the Risk of Type 2 Diabetes among Japanese Adults: Japan Epidemiology Collaboration on Occupational Health Study. PLoS One (2015) 1.40
First-trimester maternal protein intake and childhood kidney outcomes: the Generation R Study. Am J Clin Nutr (2015) 1.39
Progression from severe sepsis in pregnancy to death: a UK population-based case-control analysis. BJOG (2015) 1.38
Uptake, Accuracy, Safety, and Linkage into Care over Two Years of Promoting Annual Self-Testing for HIV in Blantyre, Malawi: A Community-Based Prospective Study. PLoS Med (2015) 1.36
Handling missing data in RCTs; a review of the top medical journals. BMC Med Res Methodol (2014) 1.35
Critical appraisal and data extraction for systematic reviews of prediction modelling studies: the CHARMS checklist. PLoS Med (2014) 1.35
Impact of the National Health Service Health Check on cardiovascular disease risk: a difference-in-differences matching analysis. CMAJ (2016) 1.35
Factors associated with non-response in routine use of patient reported outcome measures after elective surgery in England. Health Qual Life Outcomes (2012) 1.31
Quality of care of people with type 2 diabetes in eight European countries: findings from the Guideline Adherence to Enhance Care (GUIDANCE) study. Diabetes Care (2013) 1.30
Reference values for healthy human myocardium using a T1 mapping methodology: results from the International T1 Multicenter cardiovascular magnetic resonance study. J Cardiovasc Magn Reson (2014) 1.27
Adolescent self-harm and suicidal thoughts in the ALSPAC cohort: a self-report survey in England. BMC Psychiatry (2012) 1.26
Remediating organizational functioning in children with ADHD: immediate and long-term effects from a randomized controlled trial. J Consult Clin Psychol (2012) 1.25
Should gestational weight gain recommendations be tailored by maternal characteristics? Am J Epidemiol (2011) 1.25
Regional variations in ambulatory care and incidence of cardiovascular events. CMAJ (2017) 1.24
A low intensity, community based lifestyle programme to prevent weight gain in women with young children: cluster randomised controlled trial. BMJ (2010) 1.24
Prevalence of diabetes and prediabetes and their risk factors among Bangladeshi adults: a nationwide survey. Bull World Health Organ (2014) 1.24
Strategies to diagnose ovarian cancer: new evidence from phase 3 of the multicentre international IOTA study. Br J Cancer (2014) 1.22
Health literacy of Dutch adults: a cross sectional survey. BMC Public Health (2013) 1.22
Reduced sample sizes for atrophy outcomes in Alzheimer's disease trials: baseline adjustment. Neurobiol Aging (2010) 1.21
Serum glucose levels for predicting death in patients admitted to hospital for community acquired pneumonia: prospective cohort study. BMJ (2012) 1.20
Sleeping problems and suicide in 75,000 Norwegian adults: a 20 year follow-up of the HUNT I study. Sleep (2011) 1.19
Variation in advanced stage at diagnosis of lung and female breast cancer in an English region 2006-2009. Br J Cancer (2012) 1.19
Prenatal exposure to residential air pollution and infant mental development: modulation by antioxidants and detoxification factors. Environ Health Perspect (2011) 1.18
Use of record-linkage to handle non-response and improve alcohol consumption estimates in health survey data: a study protocol. BMJ Open (2013) 1.17
Internet-based randomized controlled trials: a systematic review. J Am Med Inform Assoc (2012) 1.17
Multiple imputation: a mature approach to dealing with missing data. Intensive Care Med (2015) 1.16
Air pollution exposure and markers of placental growth and function: the generation R study. Environ Health Perspect (2012) 1.16
Quality of diabetes care in Dutch care groups: no differences between diabetes patients with and without co-morbidity. Int J Integr Care (2013) 1.16
Breast density, body mass index, and risk of tumor marker-defined subtypes of breast cancer. Ann Epidemiol (2012) 1.16
Maternal vitamin D status and spontaneous preterm birth by placental histology in the US Collaborative Perinatal Project. Am J Epidemiol (2013) 1.15
Differences in access and patient outcomes across antiretroviral treatment clinics in the Free State province: a prospective cohort study. S Afr Med J (2010) 1.15
Maternal serum 25-hydroxyvitamin D and measures of newborn and placental weight in a U.S. multicenter cohort study. J Clin Endocrinol Metab (2012) 1.14
Repeated exposure to socioeconomic disadvantage and health selection as life course pathways to mid-life depressive and anxiety disorders. Soc Psychiatry Psychiatr Epidemiol (2010) 1.13
Long-term efficacy of psychological treatments for binge eating disorder. Br J Psychiatry (2012) 1.13
Multiple imputation of missing blood pressure covariates in survival analysis. Stat Med (1999) 18.50
Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. BMJ (2007) 14.52
A comparison of inclusive and restrictive strategies in modern missing data procedures. Psychol Methods (2001) 14.35
Derivation and validation of QRISK, a new cardiovascular disease risk score for the United Kingdom: prospective open cohort study. BMJ (2007) 8.87
Using the outcome for imputation of missing predictor values was preferred. J Clin Epidemiol (2006) 7.83
Much ado about nothing: A comparison of missing data methods and software to fit incomplete data regression models. Am Stat (2007) 5.53
Are missing outcome data adequately handled? A review of published randomized controlled trials in major medical journals. Clin Trials (2004) 5.26
Use of multiple imputation in the epidemiologic literature. Am J Epidemiol (2008) 3.76
Biased estimation of the odds ratio in case-control studies due to the use of ad hoc methods of correcting for missing values for confounding variables. Am J Epidemiol (1991) 3.72
Sensitivity analysis after multiple imputation under missing at random: a weighting approach. Stat Methods Med Res (2007) 3.67
Robustness of a multivariate normal approximation for imputation of incomplete binary data. Stat Med (2007) 3.26
Imputation is beneficial for handling missing data in predictive models. J Clin Epidemiol (2007) 3.08
On the performance of random-coefficient pattern-mixture models for non-ignorable drop-out. Stat Med (2003) 2.94
Cost-effectiveness in clinical trials: using multiple imputation to deal with incomplete cost data. Clin Trials (2007) 2.45
Multiple imputation using chained equations: Issues and guidance for practice. Stat Med (2010) 17.36
Major lipids, apolipoproteins, and risk of vascular disease. JAMA (2009) 10.58
Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies. Lancet (2011) 9.07
Smoking cessation support delivered via mobile phone text messaging (txt2stop): a single-blind, randomised trial. Lancet (2011) 8.19
Nasal CPAP or intubation at birth for very preterm infants. N Engl J Med (2008) 7.21
Prognosis and prognostic research: validating a prognostic model. BMJ (2009) 6.54
C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med (2012) 6.39
Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality. JAMA (2009) 5.63
The design of simulation studies in medical statistics. Stat Med (2006) 5.30
Are missing outcome data adequately handled? A review of published randomized controlled trials in major medical journals. Clin Trials (2004) 5.26
Multivariate meta-analysis: potential and promise. Stat Med (2011) 5.26
The cost of dichotomising continuous variables. BMJ (2006) 5.12
Prognosis and prognostic research: what, why, and how? BMJ (2009) 4.46
Prognosis and prognostic research: application and impact of prognostic models in clinical practice. BMJ (2009) 4.38
Imputing missing covariate values for the Cox model. Stat Med (2009) 4.31
General growth mixture modeling for randomized preventive interventions. Biostatistics (2002) 4.00
Lipid-related markers and cardiovascular disease prediction. JAMA (2012) 3.91
Sensitivity analysis after multiple imputation under missing at random: a weighting approach. Stat Methods Med Res (2007) 3.67
Low-dose dexamethasone facilitates extubation among chronically ventilator-dependent infants: a multicenter, international, randomized, controlled trial. Pediatrics (2006) 3.62
Review of inverse probability weighting for dealing with missing data. Stat Methods Med Res (2011) 3.56
Bias and efficiency of multiple imputation compared with complete-case analysis for missing covariate values. Stat Med (2010) 3.41
Standardized interpretation of paediatric chest radiographs for the diagnosis of pneumonia in epidemiological studies. Bull World Health Organ (2005) 3.36
Cannabis use and mental health in young people: cohort study. BMJ (2002) 3.26
The epidemiology of childhood cardiomyopathy in Australia. N Engl J Med (2003) 3.07
Extending DerSimonian and Laird's methodology to perform multivariate random effects meta-analyses. Stat Med (2010) 3.07
Undue reliance on I(2) in assessing heterogeneity may mislead. BMC Med Res Methodol (2008) 3.06
Risk prediction models: II. External validation, model updating, and impact assessment. Heart (2012) 3.05
Multiple imputation for missing data: fully conditional specification versus multivariate normal imputation. Am J Epidemiol (2010) 3.03
Effect of a partially hydrolyzed whey infant formula at weaning on risk of allergic disease in high-risk children: a randomized controlled trial. J Allergy Clin Immunol (2011) 2.96
Analyzing incomplete longitudinal clinical trial data. Biostatistics (2004) 2.82
Teenage drinking and the onset of alcohol dependence: a cohort study over seven years. Addiction (2004) 2.80
Risk prediction models: I. Development, internal validation, and assessing the incremental value of a new (bio)marker. Heart (2012) 2.76
Reverse gateways? Frequent cannabis use as a predictor of tobacco initiation and nicotine dependence. Addiction (2005) 2.74
Time of birth and risk of neonatal death at term: retrospective cohort study. BMJ (2010) 2.74
Recalibration of risk prediction models in a large multicenter cohort of admissions to adult, general critical care units in the United Kingdom. Crit Care Med (2006) 2.69
How should variable selection be performed with multiply imputed data? Stat Med (2008) 2.65
Methodological challenges in online trials. J Med Internet Res (2009) 2.64
A new risk prediction model for critical care: the Intensive Care National Audit & Research Centre (ICNARC) model. Crit Care Med (2007) 2.64
The natural history of self-harm from adolescence to young adulthood: a population-based cohort study. Lancet (2011) 2.59
Adolescent precursors of cannabis dependence: findings from the Victorian Adolescent Health Cohort Study. Br J Psychiatry (2003) 2.57
Quantifying the impact of between-study heterogeneity in multivariate meta-analyses. Stat Med (2012) 2.52
Selection of important variables and determination of functional form for continuous predictors in multivariable model building. Stat Med (2007) 2.46
Mediation and moderation of treatment effects in randomised controlled trials of complex interventions. Stat Methods Med Res (2009) 2.43
An analysis of prospective risk factors for aortic stiffness in men: 20-year follow-up from the Caerphilly prospective study. Hypertension (2010) 2.40
Detection of a widespread clone of Pseudomonas aeruginosa in a pediatric cystic fibrosis clinic. Am J Respir Crit Care Med (2002) 2.38
DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome. Hum Mol Genet (2010) 2.33
A comparison of imputation techniques for handling missing predictor values in a risk model with a binary outcome. Stat Methods Med Res (2007) 2.31
Prognostic model for survival in patients with metastatic renal cell carcinoma: results from the international kidney cancer working group. Clin Cancer Res (2011) 2.27
Development and validation of a prognostic model for survival time data: application to prognosis of HIV positive patients treated with antiretroviral therapy. Stat Med (2004) 2.26
Development and validation of a prediction model with missing predictor data: a practical approach. J Clin Epidemiol (2009) 2.24
Regression dilution methods for meta-analysis: assessing long-term variability in plasma fibrinogen among 27,247 adults in 15 prospective studies. Int J Epidemiol (2006) 2.22
Strategies for multiple imputation in longitudinal studies. Am J Epidemiol (2010) 2.15
Community epidemiology of human metapneumovirus, human coronavirus NL63, and other respiratory viruses in healthy preschool-aged children using parent-collected specimens. Pediatrics (2007) 2.13
Combining estimates of interest in prognostic modelling studies after multiple imputation: current practice and guidelines. BMC Med Res Methodol (2009) 2.12
Predictors of neonatal sepsis in developing countries. Pediatr Infect Dis J (2003) 2.10
A quantitative meta-analysis of population-based studies of premorbid intelligence and schizophrenia. Schizophr Res (2011) 2.09
Speeding up the evaluation of new agents in cancer. J Natl Cancer Inst (2008) 2.08
Dietary fiber and colorectal cancer risk: a nested case-control study using food diaries. J Natl Cancer Inst (2010) 2.07
Comparison of techniques for handling missing covariate data within prognostic modelling studies: a simulation study. BMC Med Res Methodol (2010) 2.05
Perinatal risk factors altering regional brain structure in the preterm infant. Brain (2006) 2.02
Financial stress, smoking cessation and relapse: results from a prospective study of an Australian national sample. Addiction (2006) 1.99
Interobserver variability of the 5-minute Apgar score. J Pediatr (2006) 1.95
Randomised controlled trial of acute mental health care by a crisis resolution team: the north Islington crisis study. BMJ (2005) 1.94
Promoting social inclusion in schools: a group-randomized trial of effects on student health risk behavior and well-being. Am J Public Health (2006) 1.94
A longitudinal study of the effects of adolescent cannabis use on high school completion. Addiction (2003) 1.91
Lower airway inflammation in infants with cystic fibrosis detected by newborn screening. Pediatr Pulmonol (2005) 1.90
Issues in multiple imputation of missing data for large general practice clinical databases. Pharmacoepidemiol Drug Saf (2010) 1.85
Bed sharing when parents do not smoke: is there a risk of SIDS? An individual level analysis of five major case-control studies. BMJ Open (2013) 1.84
Risk factors for intussusception in infants in Vietnam and Australia: adenovirus implicated, but not rotavirus. J Pediatr (2006) 1.84
Maternal 25-hydroxyvitamin D and parathyroid hormone concentrations and offspring birth size. J Clin Endocrinol Metab (2005) 1.84
The persistence of the association between adolescent cannabis use and common mental disorders into young adulthood. Addiction (2012) 1.83
Social capital and mental health: a comparative analysis of four low income countries. Soc Sci Med (2006) 1.81
Issues in applying multi-arm multi-stage methodology to a clinical trial in prostate cancer: the MRC STAMPEDE trial. Trials (2009) 1.81
Second-trimester maternal serum levels of alpha-fetoprotein and the subsequent risk of sudden infant death syndrome. N Engl J Med (2004) 1.78
Mode of delivery and the risk of delivery-related perinatal death among twins at term: a retrospective cohort study of 8073 births. BJOG (2005) 1.76
Imputation methods for missing outcome data in meta-analysis of clinical trials. Clin Trials (2008) 1.76
Clinical features and outcomes of childhood dilated cardiomyopathy: results from a national population-based study. Circulation (2006) 1.75
Prognostic model for HIV-1 disease progression in patients starting antiretroviral therapy was validated using independent data. J Clin Epidemiol (2005) 1.72
Direct likelihood analysis versus simple forms of imputation for missing data in randomized clinical trials. Clin Trials (2005) 1.70
Correcting for optimistic prediction in small data sets. Am J Epidemiol (2014) 1.69
Outcomes of crises before and after introduction of a crisis resolution team. Br J Psychiatry (2005) 1.68
Reporting methods in studies developing prognostic models in cancer: a review. BMC Med (2010) 1.68
The effect of measurement error in risk factors that change over time in cohort studies: do simple methods overcorrect for 'regression dilution'? Int J Epidemiol (2005) 1.66
Impact and costs of incentives to reduce attrition in online trials: two randomized controlled trials. J Med Internet Res (2011) 1.66
Reporting performance of prognostic models in cancer: a review. BMC Med (2010) 1.65
Timing of infant feeding in relation to childhood asthma and allergic diseases. J Allergy Clin Immunol (2012) 1.62
Interactions between treatment and continuous covariates: a step toward individualizing therapy. J Clin Oncol (2008) 1.62
Comparative field evaluation of combinations of long-lasting insecticide treated nets and indoor residual spraying, relative to either method alone, for malaria prevention in an area where the main vector is Anopheles arabiensis. Parasit Vectors (2013) 1.61
On-line randomized controlled trial of an internet based psychologically enhanced intervention for people with hazardous alcohol consumption. PLoS One (2011) 1.61