Published in Life Sci on May 27, 2009
A prostatic intraepithelial neoplasia-dependent p27 Kip1 checkpoint induces senescence and inhibits cell proliferation and cancer progression. Cancer Cell (2008) 2.48
Retinoblastoma protein regulates cell proliferation, differentiation, and endoreduplication in plants. Plant J (2005) 1.23
Effects of recombinant adenovirus-mediated uncoupling protein 2 overexpression on endothelial function and apoptosis. Circ Res (2005) 1.20
Structure of malonamidase E2 reveals a novel Ser-cisSer-Lys catalytic triad in a new serine hydrolase fold that is prevalent in nature. EMBO J (2002) 1.20
Depletion of UDP-D-apiose/UDP-D-xylose synthases results in rhamnogalacturonan-II deficiency, cell wall thickening, and cell death in higher plants. J Biol Chem (2006) 1.18
D-glucosamine inhibits proliferation of human cancer cells through inhibition of p70S6K. Biochem Biophys Res Commun (2007) 1.17
Glucose deprivation regulates KATP channel trafficking via AMP-activated protein kinase in pancreatic beta-cells. Diabetes (2009) 1.13
Relationships between Dietary Habits and Allostatic Load Index in Metabolic Syndrome Patients. Korean J Fam Med (2013) 1.08
Efficacy of multimodal pain control protocol in the setting of total hip arthroplasty. Clin Orthop Surg (2009) 1.08
A modeling approach to energy savings of flying Canada geese using computational fluid dynamics. J Theor Biol (2012) 1.07
In vitro inhibition of influenza A virus infection by marine microalga-derived sulfated polysaccharide p-KG03. Antiviral Res (2011) 1.00
The impact of depression and anxiety on self-assessed pain, disability, and quality of life in patients scheduled for rotator cuff repair. J Shoulder Elbow Surg (2013) 0.98
Up-regulation of human beta-defensin 2 by interleukin-1beta in A549 cells: involvement of PI3K, PKC, p38 MAPK, JNK, and NF-kappaB. Biochem Biophys Res Commun (2004) 0.95
Curcumin inhibits the expression of COX-2 in UVB-irradiated human keratinocytes (HaCaT) by inhibiting activation of AP-1: p38 MAP kinase and JNK as potential upstream targets. Exp Mol Med (2005) 0.95
Glucagon-like peptide-1 enhances glucokinase activity in pancreatic β-cells through the association of Epac2 with Rim2 and Rab3A. Endocrinology (2011) 0.93
Production of multiple transgenic Yucatan miniature pigs expressing human complement regulatory factors, human CD55, CD59, and H-transferase genes. PLoS One (2013) 0.93
Sanguinarine induces apoptosis in A549 human lung cancer cells primarily via cellular glutathione depletion. Toxicol In Vitro (2008) 0.92
Progressive impairment of erythrocyte deformability as indicator of microangiopathy in type 2 diabetes mellitus. Clin Hemorheol Microcirc (2007) 0.92
Pulmonary and cerebral fat embolism syndrome after total knee replacement. J Clin Med Res (2013) 0.91
Assessment of haemodynamic effects of surgical correction for severe functional tricuspid regurgitation: cardiac magnetic resonance imaging study. Eur Heart J (2010) 0.91
Assessment of prescribed herbal medicine on liver function in Korea: a prospective observational study. J Altern Complement Med (2008) 0.91
Retronectin enhances lentivirus-mediated gene delivery into hematopoietic progenitor cells. Biologicals (2009) 0.90
Leptomycin B-induced apoptosis is mediated through caspase activation and down-regulation of Mcl-1 and XIAP expression, but not through the generation of ROS in U937 leukemia cells. Biochem Pharmacol (2004) 0.90
Thimerosal induces apoptosis and G2/M phase arrest in human leukemia cells. Mol Carcinog (2006) 0.90
Bone marrow-derived mesenchymal stem cells prevent the loss of Niemann-Pick type C mouse Purkinje neurons by correcting sphingolipid metabolism and increasing sphingosine-1-phosphate. Stem Cells (2010) 0.90
Cilostazol inhibits vascular smooth muscle cell growth by downregulation of the transcription factor E2F. Hypertension (2005) 0.90
Two histopathologically different diseases: hormone receptor-positive and hormone receptor-negative tumors in HER2-positive breast cancer. Breast Cancer Res Treat (2014) 0.89
Deubiquitinating enzyme USP36 contains the PEST motif and is polyubiquitinated. Biochem Biophys Res Commun (2005) 0.89
Cadmium specifically induces MKP-1 expression via the glutathione depletion-mediated p38 MAPK activation in C6 glioma cells. Neurosci Lett (2008) 0.89
LDL activates signaling pathways leading to an increase in cytosolic free calcium and stimulation of CD11b expression in monocytes. J Lipid Res (2003) 0.88
Inflammatory cytokines are overexpressed in the subacromial bursa of frozen shoulder. J Shoulder Elbow Surg (2012) 0.88
Glucosamine induces autophagic cell death through the stimulation of ER stress in human glioma cancer cells. Biochem Biophys Res Commun (2010) 0.88
Regulation of insulin secretion and beta-cell mass by activating signal cointegrator 2. Mol Cell Biol (2006) 0.88
Se-methylselenocysteine induces apoptosis through caspase activation and Bax cleavage mediated by calpain in SKOV-3 ovarian cancer cells. Cancer Lett (2002) 0.87
Correlations between Janus kinase 2 V617F allele burdens and clinicohematologic parameters in myeloproliferative neoplasms. Ann Lab Med (2012) 0.87
HAUSP, a deubiquitinating enzyme for p53, is polyubiquitinated, polyneddylated, and dimerized. FEBS Lett (2005) 0.87
Melatonin down-regulates HIF-1 alpha expression through inhibition of protein translation in prostate cancer cells. J Pineal Res (2009) 0.87
Manganese-mediated up-regulation of HIF-1alpha protein in Hep2 human laryngeal epithelial cells via activation of the family of MAPKs. Toxicol In Vitro (2010) 0.87
Inhibition of influenza virus internalization by (-)-epigallocatechin-3-gallate. Antiviral Res (2013) 0.86
Operative treatment of clavicle midshaft fractures: comparison between reconstruction plate and reconstruction locking compression plate. Clin Orthop Surg (2010) 0.86
Myocardial scarring on cardiovascular magnetic resonance in asymptomatic or minimally symptomatic patients with "pure" apical hypertrophic cardiomyopathy. J Cardiovasc Magn Reson (2012) 0.86
Catalase induced expression of inflammatory mediators via activation of NF-kappaB, PI3K/AKT, p70S6K, and JNKs in BV2 microglia. Cell Signal (2005) 0.86
Homeodomain protein CDX2 regulates COX-2 expression in colorectal cancer. Biochem Biophys Res Commun (2004) 0.86
Inhibitory modulation of ATP-sensitive potassium channels by gallate-ester moiety of (-)-epigallocatechin-3-gallate. Biochem Pharmacol (2005) 0.85
Virtual reality for obsessive-compulsive disorder: past and the future. Psychiatry Investig (2009) 0.84
N-phenethyl-2-phenylacetamide isolated from Xenorhabdus nematophilus induces apoptosis through caspase activation and calpain-mediated Bax cleavage in U937 cells. Int J Oncol (2003) 0.84
Alteration of immunologic responses on peripheral blood in the acute phase of ischemic stroke: blood genomic profiling study. J Neuroimmunol (2012) 0.84
Down-regulation of peroxisome proliferator-activated receptor gamma in human cervical carcinoma. Gynecol Oncol (2005) 0.84
Functional expression of single-chain variable fragment antibody against c-Met in the cytoplasm of Escherichia coli. Protein Expr Purif (2005) 0.84
IL4 receptor polymorphism is associated with increased risk of sudden deafness in Korean population. Life Sci (2005) 0.83
Growth inhibition and apoptosis induced in human leiomyoma cells by treatment with the PPAR gamma ligand ciglitizone. Mol Hum Reprod (2007) 0.83
Inhibitory effects of glucosamine on lipopolysaccharide-induced activation in microglial cells. Clin Exp Pharmacol Physiol (2005) 0.83
Endobronchial Mycobacterium avium Infection in an Immunocompetent Patient. Infect Chemother (2013) 0.83
Triptolide suppresses interleukin-1beta-induced human beta-defensin-2 mRNA expression through inhibition of transcriptional activation of NF-kappaB in A549 cells. Int J Mol Med (2007) 0.83
Uncoupling by (--)-epigallocatechin-3-gallate of ATP-sensitive potassium channels from phosphatidylinositol polyphosphates and ATP. Pharmacol Res (2007) 0.83
Upregulation of ATP-sensitive potassium channels for estrogen-mediated cell proliferation in human uterine leiomyoma cells. Gynecol Endocrinol (2008) 0.83
Taurine increases glucose sensitivity of UCP2-overexpressing beta-cells by ameliorating mitochondrial metabolism. Am J Physiol Endocrinol Metab (2004) 0.82
Tetrandrine-induced apoptosis is mediated by activation of caspases and PKC-delta in U937 cells. Biochem Pharmacol (2004) 0.82
Silibinin inhibits expression of HIF-1alpha through suppression of protein translation in prostate cancer cells. Biochem Biophys Res Commun (2009) 0.82
Effect of Green Tea Extract/Poly-γ-Glutamic Acid Complex in Obese Type 2 Diabetic Mice. Diabetes Metab J (2013) 0.82
Overexpression of cyclooxygenase-2 in NCI-H292 human alveolar epithelial carcinoma cells: roles of p38 MAPK, ERK-1/2, and PI3K/PKB signaling proteins. J Cell Biochem (2011) 0.82
D-glucosamine down-regulates HIF-1alpha through inhibition of protein translation in DU145 prostate cancer cells. Biochem Biophys Res Commun (2009) 0.82
Marine algal fucoxanthin inhibits the metastatic potential of cancer cells. Biochem Biophys Res Commun (2013) 0.82
Arsenic trioxide-induced apoptosis in U937 cells involve generation of reactive oxygen species and inhibition of Akt. Int J Oncol (2002) 0.81
Establishment of transgenic fibroblasts for producing recombinant human interferon-α and erythropoietin in bovine milk. Mol Med Rep (2012) 0.81
Platinum monolayer electrocatalyst on gold nanostructures on silicon for photoelectrochemical hydrogen evolution. ACS Nano (2013) 0.81
Fluoxetine increases the nitric oxide production via nuclear factor kappa B-mediated pathway in BV2 murine microglial cells. Neurosci Lett (2006) 0.81
Highly cross-linked polyethylene in total hip arthroplasty for osteonecrosis of the femoral head: a minimum 5-year follow-up study. J Arthroplasty (2012) 0.80
EGCG attenuates AMPA-induced intracellular calcium increase in hippocampal neurons. Biochem Biophys Res Commun (2002) 0.80
Different impacts of acute myocardial infarction on left ventricular apical and basal rotation. Eur Heart J Cardiovasc Imaging (2011) 0.80
Honokiol reduces oxidative stress, c-jun-NH2-terminal kinase phosphorylation and protects against glycochenodeoxycholic acid-induced apoptosis in primary cultured rat hepatocytes. Planta Med (2006) 0.80
Two mutations in pab-1 encoding poly(A)-binding protein show similar defects in germline stem cell proliferation but different longevity in C. elegans. Mol Cells (2010) 0.80
Effects of berberine on hippocampal neuronal damage and matrix metalloproteinase-9 activity following transient global cerebral ischemia. J Neurosci Res (2011) 0.80
Glucagon-like peptide-1 protects NSC-34 motor neurons against glucosamine through Epac-mediated glucose uptake enhancement. Neurosci Lett (2010) 0.80
Effects of (-)-epigallocatechin-3-gallate on pancreatic beta-cell damage in streptozotocin-induced diabetic rats. Eur J Pharmacol (2006) 0.80
Induction of cyclooxygenase-2 in macrophages by catalase: role of NF-kappaB and PI3K signaling pathways. Biochem Biophys Res Commun (2004) 0.79
Catalase induces the expression of inducible nitric oxide synthase through activation of NF-kappaB and PI3K signaling pathway in Raw 264.7 cells. Biochem Pharmacol (2004) 0.79
A new type of uncompetitive inhibition of tyrosinase induced by Cl- binding. Biochimie (2005) 0.79
Protective role of glucagon-like peptide-1 against glucosamine-induced cytotoxicity in pancreatic beta cells. Cell Physiol Biochem (2010) 0.79
Epigallocatechin gallate reduces hypoxia-induced apoptosis in human hepatoma cells. Life Sci (2006) 0.79
Prevention and treatment of macroangiopathy: focusing on oxidative stress. Diabetes Res Clin Pract (2004) 0.79
Establishment of inducible cAMP early repressor transgenic fibroblasts in a porcine model of human type 1 diabetes mellitus. Mol Med Rep (2012) 0.79
Towards a proteomic analysis of atopic dermatitis: a two-dimensional-polyacrylamide gel electrophoresis/mass spectrometric analysis of cultured patient-derived fibroblasts. Proteomics (2004) 0.79
Association of tumor necrosis factor-α (TNF-α) promoter polymorphisms with overweight/obesity in a Korean population. Inflamm Res (2011) 0.79