Published in Reprod Toxicol on March 13, 2009
Aryl hydrocarbon receptor activation during pregnancy, and in adult nulliparous mice, delays the subsequent development of DMBA-induced mammary tumors. Int J Cancer (2010) 0.97
Neural precursor cell proliferation is disrupted through activation of the aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Stem Cells Dev (2010) 0.89
Role of the Arylhydrocarbon Receptor (AhR) in the Pathology of Asthma and COPD. J Allergy (Cairo) (2012) 0.88
Novel cellular targets of AhR underlie alterations in neutrophilic inflammation and inducible nitric oxide synthase expression during influenza virus infection. J Immunol (2012) 0.88
Activation of the aryl hydrocarbon receptor during pregnancy in the mouse alters mammary development through direct effects on stromal and epithelial tissues. Biol Reprod (2011) 0.81
Dioxin exposure blocks lactation through a direct effect on mammary epithelial cells mediated by the aryl hydrocarbon receptor repressor. Toxicol Sci (2014) 0.77
Bis-aryloxadiazoles as effective activators of the aryl hydrocarbon receptor. Bioorg Med Chem Lett (2014) 0.76
Imprinting genes associated with endometriosis. EXCLI J (2014) 0.76
Cross-Talk in the Female Rat Mammary Gland: Influence of Aryl Hydrocarbon Receptor on Estrogen Receptor Signaling. Environ Health Perspect (2015) 0.76
Carcinogenetic mechanisms of endocrine disruptors in female cancers (Review). Oncol Rep (2016) 0.75
Chemical exposure as etiology in developmental origin of adult onset human cancer. Front Pharmacol (2011) 0.75
Maternal Resveratrol Treatment Reduces the Risk of Mammary Carcinogenesis in Female Offspring Prenatally Exposure to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin. Horm Cancer (2017) 0.75
STATs and gene regulation. Science (1997) 16.55
The aryl hydrocarbon receptor complex. Annu Rev Pharmacol Toxicol (1995) 6.37
Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane. Development (1989) 5.62
Stat5a is mandatory for adult mammary gland development and lactogenesis. Genes Dev (1997) 5.57
E-cadherin null mutant embryos fail to form a trophectoderm epithelium. Proc Natl Acad Sci U S A (1994) 5.31
Influence of a reconstituted basement membrane and its components on casein gene expression and secretion in mouse mammary epithelial cells. Proc Natl Acad Sci U S A (1987) 4.18
The search for endogenous activators of the aryl hydrocarbon receptor. Chem Res Toxicol (2007) 3.68
Signaling pathways in mammary gland development. Dev Cell (2001) 3.10
Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction. Proc Natl Acad Sci U S A (1994) 3.09
Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue. Proc Natl Acad Sci U S A (1995) 2.79
E-cadherin is a survival factor for the lactating mouse mammary gland. Mech Dev (2002) 2.63
Epithelial mouse mammary cell line exhibiting normal morphogenesis in vivo and functional differentiation in vitro. Proc Natl Acad Sci U S A (1984) 2.44
Extracellular matrix and hormones transcriptionally regulate bovine beta-casein 5' sequences in stably transfected mouse mammary cells. Proc Natl Acad Sci U S A (1990) 2.25
Dioxins: an overview. Environ Res (2006) 2.11
Developmental and reproductive toxicity of dioxins and related compounds: cross-species comparisons. Crit Rev Toxicol (1993) 2.11
Signal transducer and activator of transcription (Stat) 5 controls the proliferation and differentiation of mammary alveolar epithelium. J Cell Biol (2001) 2.05
The aryl hydrocarbon receptor, more than a xenobiotic-interacting protein. FEBS Lett (2007) 1.90
Activation of Stat5a and Stat5b by tyrosine phosphorylation is tightly linked to mammary gland differentiation. Mol Endocrinol (1996) 1.86
The DNA recognition site for the dioxin-Ah receptor complex. Nucleotide sequence and functional analysis. J Biol Chem (1988) 1.74
Fifteen years after "Wingspread"--environmental endocrine disrupters and human and wildlife health: where we are today and where we need to go. Toxicol Sci (2008) 1.71
Functional development of the mammary gland: use of expression profiling and trajectory clustering to reveal changes in gene expression during pregnancy, lactation, and involution. J Mammary Gland Biol Neoplasia (2003) 1.67
Recruitment of the NCoA/SRC-1/p160 family of transcriptional coactivators by the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator complex. Mol Cell Biol (2002) 1.58
Persistent abnormalities in the rat mammary gland following gestational and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Toxicol Sci (2002) 1.54
Activation of receptor-associated tyrosine kinase JAK2 by prolactin. J Biol Chem (1994) 1.46
Jak2/Stat5 signaling in mammogenesis, breast cancer initiation and progression. J Mammary Gland Biol Neoplasia (2008) 1.45
Ah receptor agonists as endocrine disruptors: antiestrogenic activity and mechanisms. Toxicol Lett (1998) 1.44
2,3,7,8-tetrachlorodibenzo-p-dioxin-induced degradation of aryl hydrocarbon receptor (AhR) by the ubiquitin-proteasome pathway. Role of the transcription activaton and DNA binding of AhR. J Biol Chem (2000) 1.43
The mechanism of AH receptor protein down-regulation (degradation) and its impact on AH receptor-mediated gene regulation. Chem Biol Interact (2002) 1.42
A novel effect of dioxin: exposure during pregnancy severely impairs mammary gland differentiation. Toxicol Sci (2004) 1.41
Nuclear factor I and mammary gland factor (STAT5) play a critical role in regulating rat whey acidic protein gene expression in transgenic mice. Mol Cell Biol (1995) 1.37
Estrogen receptor and aryl hydrocarbon receptor signaling pathways. Nucl Recept Signal (2006) 1.35
Modulation of gene expression and endocrine response pathways by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds. Pharmacol Ther (1995) 1.30
Understanding dioxin developmental toxicity using the zebrafish model. Birth Defects Res A Clin Mol Teratol (2006) 1.29
Regulation of the sheep beta-lactoglobulin gene by lactogenic hormones is mediated by a transcription factor that binds an interferon-gamma activation site-related element. Mol Endocrinol (1994) 1.24
Cadherins and the mammary gland. J Cell Biochem (2005) 1.19
Activation of the dioxin/aryl hydrocarbon receptor (AhR) modulates cell plasticity through a JNK-dependent mechanism. Oncogene (2006) 1.18
Interactions of nuclear receptor coactivator/corepressor proteins with the aryl hydrocarbon receptor complex. Arch Biochem Biophys (1999) 1.15
Alveolar and lactogenic differentiation. J Mammary Gland Biol Neoplasia (2006) 1.13
Timing of exposure and mammary cancer risk. J Mammary Gland Biol Neoplasia (2002) 1.09
Dioxin-responsive AHRE-II gene battery: identification by phylogenetic footprinting. Biochem Biophys Res Commun (2004) 1.06
Expression and activity of aryl hydrocarbon receptors in development and cancer. Crit Rev Eukaryot Gene Expr (2008) 1.05
Characterization of 2,3,7,8-tetrachlorodibenzofuran-dependent suppression and AH receptor pathway gene expression in the developing mouse mammary gland. Toxicol Appl Pharmacol (1998) 1.01
The wildlife/human connection: modernizing risk decisions. Environ Health Perspect (1994) 1.00
Expression of the cytoplasmic domain of E-cadherin induces precocious mammary epithelial alveolar formation and affects cell polarity and cell-matrix integrity. Dev Biol (1999) 0.99
In utero effects of chemicals on reproductive tissues in females. Toxicol Appl Pharmacol (2004) 0.98
Characterization of the mouse Cyp1B1 gene. Identification of an enhancer region that directs aryl hydrocarbon receptor-mediated constitutive and induced expression. J Biol Chem (1998) 0.96
Prenatal TCDD exposure predisposes for mammary cancer in rats. Reprod Toxicol (2006) 0.95
Stat5 in the mammary gland: controlling normal development and cancer. J Cell Physiol (2006) 0.92
Identification of dioxin-responsive elements (DREs) in the 5' regions of putative dioxin-inducible genes. Chem Biol Interact (1996) 0.92
Significant effects of mild endogenous hormonal changes in humans: considerations for low-dose testing. Environ Health Perspect (2001) 0.90
Molecular targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) within the zebrafish ovary: insights into TCDD-induced endocrine disruption and reproductive toxicity. Reprod Toxicol (2007) 0.86
AhR transcriptional activity in serum of Inuits across Greenlandic districts. Environ Health (2007) 0.82
Ah receptor regulation of mouse Cyp1B1 is additionally modulated by a second novel complex that forms at two AhR response elements. Toxicol Appl Pharmacol (2003) 0.81
Interactions between metabolism of trace metals and xenobiotic agonists of the aryl hydrocarbon receptor in the antarctic fish Trematomus bernacchii: environmental perspectives. Environ Toxicol Chem (2005) 0.77
Neonatal hyperoxia enhances the inflammatory response in adult mice infected with influenza A virus. Am J Respir Crit Care Med (2008) 1.45
A novel effect of dioxin: exposure during pregnancy severely impairs mammary gland differentiation. Toxicol Sci (2004) 1.41
Aryl hydrocarbon receptor activation during influenza virus infection unveils a novel pathway of IFN-gamma production by phagocytic cells. J Immunol (2007) 1.18
Activation of the aryl hydrocarbon receptor increases pulmonary neutrophilia and diminishes host resistance to influenza A virus. Am J Physiol Lung Cell Mol Physiol (2005) 1.14
Aryl hydrocarbon receptor activation reduces dendritic cell function during influenza virus infection. Toxicol Sci (2010) 1.11
Environmental toxicants and the developing immune system: a missing link in the global battle against infectious disease? Reprod Toxicol (2010) 1.10
The aryl hydrocarbon receptor affects distinct tissue compartments during ontogeny of the immune system. Toxicol Sci (2007) 1.08
The aryl hydrocarbon receptor is a modulator of anti-viral immunity. Biochem Pharmacol (2008) 1.07
The effects of maternal exposure to bisphenol A on allergic lung inflammation into adulthood. Toxicol Sci (2012) 1.00
Developmental exposure to the potent aryl hydrocarbon receptor agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin Impairs the cell-mediated immune response to infection with influenza a virus, but enhances elements of innate immunity. J Immunotoxicol (2004) 0.98
Aryl hydrocarbon receptor activation during pregnancy, and in adult nulliparous mice, delays the subsequent development of DMBA-induced mammary tumors. Int J Cancer (2010) 0.97
Fewer CTL, not enhanced NK cells, are sufficient for viral clearance from the lungs of immunocompromised mice. Cell Immunol (2003) 0.95
You AhR what you eat? Nat Immunol (2012) 0.95
Neonatal oxygen increases sensitivity to influenza A virus infection in adult mice by suppressing epithelial expression of Ear1. Am J Pathol (2012) 0.94
Effects of developmental activation of the AhR on CD4+ T-cell responses to influenza virus infection in adult mice. Environ Health Perspect (2014) 0.92
Neonatal hyperoxia alters the host response to influenza A virus infection in adult mice through multiple pathways. Am J Physiol Lung Cell Mol Physiol (2013) 0.91
Exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) renders influenza virus-specific CD8+ T cells hyporesponsive to antigen. Toxicol Sci (2003) 0.91
Activation of the aryl hydrocarbon receptor during different critical windows in pregnancy alters mammary epithelial cell proliferation and differentiation. Toxicol Sci (2009) 0.90
Developmental exposure to bisphenol A modulates innate but not adaptive immune responses to influenza A virus infection. PLoS One (2012) 0.90
A Birth Cohort Study of Maternal and Infant Serum PCB-153 and DDE Concentrations and Responses to Infant Tuberculosis Vaccination. Environ Health Perspect (2015) 0.89
Aryl hydrocarbon receptor targets pathways extrinsic to bone marrow cells to enhance neutrophil recruitment during influenza virus infection. Toxicol Sci (2007) 0.89
Novel cellular targets of AhR underlie alterations in neutrophilic inflammation and inducible nitric oxide synthase expression during influenza virus infection. J Immunol (2012) 0.88
Examining the relationship between impaired host resistance and altered immune function in mice treated with TCDD. Toxicology (2003) 0.88
A cohort study of developmental polychlorinated biphenyl (PCB) exposure in relation to post-vaccination antibody response at 6-months of age. Environ Res (2010) 0.88
A dose-response study of the effects of prenatal and lactational exposure to TCDD on the immune response to influenza a virus. J Toxicol Environ Health A (2006) 0.86
Protection against lethal challenge with Streptococcus pneumoniae is conferred by aryl hydrocarbon receptor activation but is not associated with an enhanced inflammatory response. Infect Immun (2006) 0.86
Exacerbation of lung radiation injury by viral infection: the role of Clara cells and Clara cell secretory protein. Radiat Res (2013) 0.86
Differential consequences of two distinct AhR ligands on innate and adaptive immune responses to influenza A virus. Toxicol Sci (2013) 0.85
Maternal and early postnatal polychlorinated biphenyl exposure in relation to total serum immunoglobulin concentrations in 6-month-old infants. J Immunotoxicol (2011) 0.84
Memory CD8+ T cells are sufficient to alleviate impaired host resistance to influenza A virus infection caused by neonatal oxygen supplementation. Clin Vaccine Immunol (2012) 0.83
Cumulative neonatal oxygen exposure predicts response of adult mice infected with influenza A virus. Pediatr Pulmonol (2014) 0.81
Lung irradiation increases mortality after influenza A virus challenge occurring late after exposure. Int J Radiat Oncol Biol Phys (2012) 0.81
Activation of the aryl hydrocarbon receptor during pregnancy in the mouse alters mammary development through direct effects on stromal and epithelial tissues. Biol Reprod (2011) 0.81
Neonatal hyperoxia increases sensitivity of adult mice to bleomycin-induced lung fibrosis. Am J Respir Cell Mol Biol (2012) 0.81
Neonatal oxygen exposure alters airway hyper-responsiveness but not the response to allergen challenge in adult mice. Pediatr Allergy Immunol (2014) 0.80
Increased mortality associated with TCDD exposure in mice infected with influenza A virus is not due to severity of lung injury or alterations in Clara cell protein content. Chem Biol Interact (2005) 0.79
Neither direct nor developmental exposure to bisphenol A alters the severity of experimental inflammatory colitis in mice. J Immunotoxicol (2013) 0.78
T cell receptor transgenic mice provide novel insights into understanding cellular targets of TCDD: suppression of antibody production, but not the response of CD8(+) T cells, during infection with influenza virus. Toxicol Appl Pharmacol (2003) 0.78
Immunotoxicology: fifty years of global scientific progress. J Immunotoxicol (2012) 0.75
Diverse gene expression pattern during 5-fluorouridine-induced apoptosis. Int J Oncol (2005) 0.75