Published in Metabolism on August 01, 1977
Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2. Nat Genet (1996) 5.15
Insulin resistance and cigarette smoking. Lancet (1992) 4.10
The relationship between cognition and action: performance of children 3 1/2-7 years old on a Stroop-like day-night test. Cognition (1994) 4.08
Insulin resistance as a predictor of age-related diseases. J Clin Endocrinol Metab (2001) 3.31
Relationship between resistance to insulin-mediated glucose uptake, urinary uric acid clearance, and plasma uric acid concentration. JAMA (1991) 3.01
Enhanced proportion of small adipose cells in insulin-resistant vs insulin-sensitive obese individuals implicates impaired adipogenesis. Diabetologia (2007) 2.71
Comparison of impedance to insulin-mediated glucose uptake in normal subjects and in subjects with latent diabetes. J Clin Invest (1970) 2.68
Structure and properties of a bovine liver UGA suppressor serine tRNA with a tryptophan anticodon. Cell (1981) 2.58
Inhibition by insulin of valine turnover in liver. Evidence for a general control of proteolysis. J Biol Chem (1970) 2.54
Coronary artery disease in Chinese males without hypercholesterolaemia. J Intern Med (1990) 2.54
A new rat model of type 2 diabetes: the fat-fed, streptozotocin-treated rat. Metabolism (2000) 2.49
A single-transformation gene function test in diploid Candida albicans. J Bacteriol (2000) 2.47
Fructose-induced insulin resistance and hypertension in rats. Hypertension (1987) 2.43
Effects of a quick-release form of bromocriptine (Ergoset) on fasting and postprandial plasma glucose, insulin, lipid, and lipoprotein concentrations in obese nondiabetic hyperinsulinemic women. Diabetes Care (1997) 2.40
Development of the ability to use recall to guide action, as indicated by infants' performance on AB. Child Dev (1985) 2.34
Opal suppressor serine tRNAs from bovine liver form phosphoseryl-tRNA. Proc Natl Acad Sci U S A (1982) 2.24
Relationship between several surrogate estimates of insulin resistance and quantification of insulin-mediated glucose disposal in 490 healthy nondiabetic volunteers. Diabetes Care (2000) 2.22
Resistance to insulin-mediated glucose disposal as a predictor of cardiovascular disease. J Clin Endocrinol Metab (1998) 2.21
Nonketotic diabetes mellitus: insulin deficiency or insulin resistance? Am J Med (1976) 2.13
Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists. Nature (1997) 2.12
Alkaline response genes of Saccharomyces cerevisiae and their relationship to the RIM101 pathway. J Biol Chem (2000) 2.12
Role of insulin in endogenous hypertriglyceridemia. J Clin Invest (1967) 2.00
Documentation of hyperglucagonemia throughout the day in nonobese and obese patients with noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab (1987) 1.96
Effects of weight reduction on obesity. Studies of lipid and carbohydrate metabolism in normal and hyperlipoproteinemic subjects. J Clin Invest (1974) 1.92
Effect of metformin on carbohydrate and lipoprotein metabolism in NIDDM patients. Diabetes Care (1990) 1.90
Evaluation of octreotide to assess insulin-mediated glucose disposal by the insulin suppression test. Diabetologia (1994) 1.87
Reappraisal of the role of insulin in hypertriglyceridemia. Am J Med (1974) 1.84
Kinetics of triglyceride turnover of very low density lipoproteins of human plasma. J Clin Invest (1965) 1.83
Insulin resistance in pulmonary arterial hypertension. Eur Respir J (2008) 1.80
Demonstration of insulin resistance in untreated adult onset diabetic subjects with fasting hyperglycemia. J Clin Invest (1975) 1.69
Effects of low-fat, high-carbohydrate diets on risk factors for ischemic heart disease in postmenopausal women. Am J Clin Nutr (1997) 1.62
National level promotion of physical activity: results from England's ACTIVE for LIFE campaign. J Epidemiol Community Health (2001) 1.61
Identification and molecular cloning of the human Blym transforming gene activated in Burkitt's lymphomas. Nature (1983) 1.58
Nongenetic mouse models of non-insulin-dependent diabetes mellitus. Metabolism (1998) 1.54
Plasma concentrations of asymmetric dimethylarginine are increased in patients with type 2 diabetes mellitus. Am J Cardiol (2001) 1.53
Insulin binding to isolated human adipocytes. Diabetes (1974) 1.53
Effects of age and obesity on insulin binding to isolated adipocytes. Endocrinology (1975) 1.50
Further evidence for a central role of adipose tissue in the antihyperglycemic effect of metformin. Diabetes Care (1998) 1.49
Insulin binding in diabetes. Relationships with plasma insulin levels and insulin sensitivity. Diabetes (1977) 1.49
From plant to patient: an ethnomedical approach to the identification of new drugs for the treatment of NIDDM. Diabetologia (1997) 1.46
Resistance to insulin-stimulated-glucose uptake in patients with hypertension. J Clin Endocrinol Metab (1988) 1.46
Light-to-moderate alcohol intake is associated with enhanced insulin sensitivity. Diabetes Care (1994) 1.44
Much ado about (almost) nothing. Diabetes Care (1997) 1.43
Enhanced glucose utilization during prolonged glucose clamp studies. Diabetes (1981) 1.42
Insulin resistance and cigarette smoking. Lancet (1992) 1.42
Ischemic left ventricular free wall rupture: prediction, diagnosis, and treatment. Ann Thorac Surg (1997) 1.41
Some retinoblastomas, osteosarcomas, and soft tissue sarcomas may share a common etiology. Proc Natl Acad Sci U S A (1988) 1.41
Variations in insulin-stimulated glucose uptake in healthy individuals with normal glucose tolerance. J Clin Endocrinol Metab (1987) 1.40
Relation between dietary vitamin intake and resistance to insulin-mediated glucose disposal in healthy volunteers. Am J Clin Nutr (1996) 1.40
Evidence for an independent relationship between insulin resistance and fasting plasma HDL-cholesterol, triglyceride and insulin concentrations. J Intern Med (1992) 1.39
Coronary heart disease in the absence of hypercholesterolaemia. J Intern Med (1990) 1.39
Pioglitazone increases the proportion of small cells in human abdominal subcutaneous adipose tissue. Obesity (Silver Spring) (2009) 1.39
Insulin delivery rate into plasma in normal and diabetic subjects. J Clin Invest (1968) 1.38
Rare germline mutations in the BRCA2 gene are associated with early-onset prostate cancer. Br J Cancer (2007) 1.38
Decreased insulin binding to lymphocytes from diabetic subjects. J Clin Invest (1974) 1.37
A quantitative ultrastructural study of microtubule content and secretory granule accumulation in parathyroid glands of phosphate- and colchicine-treated rats. J Clin Invest (1975) 1.35
High prevalence of multidrug-resistant Streptococcus pneumoniae among children in a rural Kentucky community. Pediatr Infect Dis J (1995) 1.34
Relationship between in vivo insulin resistance and decreased insulin receptors in obese man. J Clin Endocrinol Metab (1979) 1.34
Banting Lecture 1988. Role of insulin resistance in human disease. 1988. Nutrition (1997) 1.34
Insulin-independent diabetes mellitus: metabolic characteristics. Metabolism (1980) 1.32
Glucose, insulin, and triglyceride responses to high and low carbohydrate diets in man. J Clin Invest (1966) 1.32
Ambient plasma free fatty acid concentrations in noninsulin-dependent diabetes mellitus: evidence for insulin resistance. J Clin Endocrinol Metab (1985) 1.30
Insulin therapy in obese, non-insulin-dependent diabetes induces improvements in insulin action and secretion that are maintained for two weeks after insulin withdrawal. Diabetes (1984) 1.27
Insulin and blood pressure in obesity. Hypertension (1985) 1.27
The human lymphocyte: a model for the study of insulin-receptor interaction. J Clin Endocrinol Metab (1974) 1.25
Resistance to insulin suppression of plasma free fatty acid concentrations and insulin stimulation of glucose uptake in noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab (1987) 1.24
Insulin resistance, glucose intolerance and hyperinsulinemia in patients with hypertension. Am J Hypertens (1989) 1.24
Distribution and content of microtubules in relation to the transport of lipid. An ultrastructural quantitative study of the absorptive cell of the small intestine. J Cell Biol (1977) 1.23
Prevalence of plasma lipoprotein abnormalities in a free-living population of the Central Valley, California. Circulation (1972) 1.21
A role for insulin in the aetiology and course of hypertension? Lancet (1987) 1.21
Roles of insulin resistance and obesity in regulation of plasma insulin concentrations. Am J Physiol Endocrinol Metab (2000) 1.21
Demonstration of a relationship between level of physical training and insulin-stimulated glucose utilization in normal humans. Diabetes (1983) 1.19
Glucoregulation and hormonal responses to maximal exercise in non-insulin-dependent diabetes. J Appl Physiol (1985) (1990) 1.18
A comparison of the relative effects of obesity and non-insulin-dependent diabetes mellitus on in vivo insulin-stimulated glucose utilization. Diabetes (1984) 1.18
Alterations in the glucose-stimulated insulin secretory dose-response curve and in insulin clearance in nondiabetic insulin-resistant individuals. J Clin Endocrinol Metab (1997) 1.17
Relationship between heterogeneity of insulin responses and insulin resistance in normal subjects and patients with chemical diabetes. Diabetologia (1977) 1.16
Methods of RNA sequence analysis. Methods Enzymol (1983) 1.15
Plasma glucose, insulin and lipid responses to high-carbohydrate low-fat diets in normal humans. Metabolism (1983) 1.15
Insulin secretion and action in noninsulin-dependent diabetes mellitus. Is insulin resistance secondary to hypoinsulinemia? Am J Med (1983) 1.14
Effect of variations in oral fat and carbohydrate load on postprandial lipemia. Am J Clin Nutr (1995) 1.14
Factors modifying carbohydrate metabolism and effect of insulin in perfused rat liver. Am J Physiol (1971) 1.14
Effect of age on glucose-stimulated insulin release by the beta-cell of the rat. J Clin Invest (1979) 1.13
Effect of fructose feeding on insulin secretion and insulin action in the rat. Metabolism (1980) 1.13
Effect of age and diet on insulin secretion and insulin action in the rat. Diabetes (1983) 1.13
Antihyperglycemic activities of cryptolepine analogues: an ethnobotanical lead structure isolated from Cryptolepis sanguinolenta. J Med Chem (1998) 1.12
The effects of acute and chronic dexamethasone administration on insulin binding to isolated rat hepatocytes and adipocytes. Metabolism (1975) 1.12
Glucagon does not increase plasma free fatty acid and glycerol concentrations in patients with noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab (1993) 1.10
Development of insulin resistance in normal dogs following alloxan-induced insulin deficiency. Diabetologia (1977) 1.09
Effects of sulfonylurea therapy on insulin binding to mononuclear leukocytes of diabetic patients. Am J Med (1976) 1.09
Relationship between hepatic glucose production and fasting plasma glucose concentration in patients with NIDDM. Diabetes (1994) 1.09
Verbal learning and/or memory improves with glycemic control in older subjects with non-insulin-dependent diabetes mellitus. J Am Geriatr Soc (1993) 1.08
Hypertriglyceridemic mice transgenic for the human apolipoprotein C-III gene are neither insulin resistant nor hyperinsulinemic. J Lipid Res (1994) 1.08
Variations in running activity and enzymatic adaptations in voluntary running rats. J Appl Physiol (1985) (1989) 1.08
Evidence that microtubules play a permissive role in hepatocyte very low density lipoprotein secretion. J Cell Biol (1980) 1.07
Intrahepatic cholangiojejunostomy in the management of malignant biliary obstruction. Surg Gynecol Obstet (1973) 1.07
Further evidence that insulin resistance exists in patients with chemical diabetes. Diabetes (1974) 1.07
Relationship between insulin resistance, insulin secretion, very low density lipoprotein kinetics, and plasma triglyceride levels in normotriglyceridemic man. Metabolism (1981) 1.06
Mechanisms for development of diabetic hypertriglyceridemia in streptozotocin-treated rats. Effect of diet and duration of insulin deficiency. J Clin Invest (1974) 1.06