Published in Am J Trop Med Hyg on November 01, 1991
Immunization of Human Volunteers With P. Vivax Irradiated Sporozoites (SPZ-Irrad) | NCT01082341
Acquired immunity to malaria. Clin Microbiol Rev (2009) 6.24
Enhanced T cell-mediated protection against malaria in human challenges by using the recombinant poxviruses FP9 and modified vaccinia virus Ankara. Proc Natl Acad Sci U S A (2005) 2.57
Experimental human challenge infections can accelerate clinical malaria vaccine development. Nat Rev Immunol (2011) 2.53
A phase 2b randomised trial of the candidate malaria vaccines FP9 ME-TRAP and MVA ME-TRAP among children in Kenya. PLoS Clin Trials (2006) 2.33
Immunogenicity and protection of a recombinant human adenovirus serotype 35-based malaria vaccine against Plasmodium yoelii in mice. Infect Immun (2006) 1.43
The relative contribution of antibodies, CD4+ and CD8+ T cells to sporozoite-induced protection against malaria. Immunology (1993) 1.29
T-cell immunity to peptide epitopes of liver-stage antigen 1 in an area of Papua New Guinea in which malaria is holoendemic. Infect Immun (1997) 1.27
Serum cytokine profiles in experimental human malaria. Relationship to protection and disease course after challenge. J Clin Invest (1992) 1.21
Immunization of Aotus monkeys with a functional domain of the Plasmodium falciparum variant antigen induces protection against a lethal parasite line. Proc Natl Acad Sci U S A (2002) 1.16
Short-term antigen presentation and single clonal burst limit the magnitude of the CD8(+) T cell responses to malaria liver stages. Proc Natl Acad Sci U S A (2002) 1.10
Phase I safety and immunogenicity trial of Plasmodium vivax CS derived long synthetic peptides adjuvanted with montanide ISA 720 or montanide ISA 51. Am J Trop Med Hyg (2011) 1.09
Consistent safety and infectivity in sporozoite challenge model of Plasmodium vivax in malaria-naive human volunteers. Am J Trop Med Hyg (2011) 1.09
Phase I testing of a malaria vaccine composed of hepatitis B virus core particles expressing Plasmodium falciparum circumsporozoite epitopes. Infect Immun (2004) 1.07
Malaria vaccine development. Clin Microbiol Rev (1994) 1.01
Development of a quantitative flow cytometry-based assay to assess infection by Plasmodium falciparum sporozoites. Mol Biochem Parasitol (2012) 1.00
A linear peptide containing minimal T- and B-cell epitopes of Plasmodium falciparum circumsporozoite protein elicits protection against transgenic sporozoite challenge. Infect Immun (2006) 1.00
Early gamma interferon and interleukin-2 responses to vaccination predict the late resting memory in malaria-naïve and malaria-exposed individuals. Infect Immun (2006) 0.99
Self-assembled peptide nanofibers raising durable antibody responses against a malaria epitope. Biomaterials (2012) 0.99
Analysis of immune responses against T- and B-cell epitopes from Plasmodium falciparum liver-stage antigen 1 in rodent malaria models and malaria-exposed human subjects in India. Infect Immun (2000) 0.96
Sporozoite immunization of human volunteers under chemoprophylaxis induces functional antibodies against pre-erythrocytic stages of Plasmodium falciparum. Malar J (2014) 0.95
Enhanced immunogenicity of Plasmodium falciparum peptide vaccines using a topical adjuvant containing a potent synthetic Toll-like receptor 7 agonist, imiquimod. Infect Immun (2008) 0.95
Antibody-mediated and cellular immune responses induced in naive volunteers by vaccination with long synthetic peptides derived from the Plasmodium vivax circumsporozoite protein. Am J Trop Med Hyg (2011) 0.87
Why functional pre-erythrocytic and bloodstage malaria vaccines fail: a meta-analysis of fully protective immunizations and novel immunological model. PLoS One (2010) 0.87
Preclinical vaccine study of Plasmodium vivax circumsporozoite protein derived-synthetic polypeptides formulated in montanide ISA 720 and montanide ISA 51 adjuvants. Am J Trop Med Hyg (2011) 0.85
Reflections on early malaria vaccine studies, the first successful human malaria vaccination, and beyond. Vaccine (2008) 0.85
Circumsporozoite protein-specific K(d)-restricted CD8+ T cells mediate protective antimalaria immunity in sporozoite-immunized MHC-I-K(d) transgenic mice. Mediators Inflamm (2014) 0.83
Antigens for pre-erythrocytic malaria vaccines: building on success. Parasite Immunol (2009) 0.83
Quantitative PCR evaluation of cellular immune responses in Kenyan children vaccinated with a candidate malaria vaccine. PLoS One (2009) 0.81
Immune responses and protection of Aotus monkeys immunized with irradiated Plasmodium vivax sporozoites. Am J Trop Med Hyg (2011) 0.80
Human CD8+ T cells mediate protective immunity induced by a human malaria vaccine in human immune system mice. Vaccine (2016) 0.78
Colocalization of a CD1d-Binding Glycolipid with a Radiation-Attenuated Sporozoite Vaccine in Lymph Node-Resident Dendritic Cells for a Robust Adjuvant Effect. J Immunol (2015) 0.77
Characterization of immunoglobulin G antibodies to Plasmodium falciparum sporozoite surface antigen MB2 in malaria exposed individuals. Malar J (2009) 0.77
HLA-A*01-restricted cytotoxic T-lymphocyte epitope from the Plasmodium falciparum circumsporozoite protein. Infect Immun (2001) 0.77
Grammomys surdaster, the Natural Host for Plasmodium berghei Parasites, as a Model to Study Whole-Organism Vaccines against Malaria. Am J Trop Med Hyg (2017) 0.76
Optimized Malaria-antigens delivered by immunostimulating reconstituted influenza virosomes. Wien Klin Wochenschr (2006) 0.76
Molecular cloning and sequencing of the circumsporozoite protein gene from Plasmodium falciparum strain FCC-1/HN and expression of the gene in Mycobacteria. J Clin Microbiol (2001) 0.75
Skin scarification with Plasmodium falciparum peptide vaccine using synthetic TLR agonists as adjuvants elicits malaria sporozoite neutralizing immunity. Sci Rep (2016) 0.75
Mosquito bite immunization with radiation-attenuated Plasmodium falciparum sporozoites: safety, tolerability, protective efficacy and humoral immunogenicity. Malar J (2016) 0.75
Still seeking an effective "one-two" malaria vaccine punch. Mol Ther (2012) 0.75
A potent adjuvant effect of a CD1d-binding NKT cell ligand in human immune system mice. Expert Rev Vaccines (2016) 0.75
The genome of black cottonwood, Populus trichocarpa (Torr. & Gray). Science (2006) 21.03
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature (2000) 19.15
Differentiation of the "Intermediate" Coli-Like Bacteria. J Bacteriol (1942) 14.28
Differential Reactions in the Colon Group of Bacteria. Am J Public Health Nations Health (1934) 13.94
NOTES ON BACT. COLI AND BACT. AEROGENES. Am J Public Health (N Y) (1921) 9.89
The Effect of Metabolites of Escherichia coli on the Growth of Coli-Aerogenes Bacteria. J Bacteriol (1947) 9.43
Toxin, toxin-coregulated pili, and the toxR regulon are essential for Vibrio cholerae pathogenesis in humans. J Exp Med (1988) 9.19
Characteristics of Coli-like Microorganisms from the Soil. J Bacteriol (1917) 8.18
A phage P22 gene controlling integration of prophage. Virology (1967) 7.98
Antibiotic Interrelationships among the Enteric Group of Bacteria. J Bacteriol (1947) 7.44
Immunological method for mapping genes on Drosophila polytene chromosomes. Proc Natl Acad Sci U S A (1982) 7.08
Cloning of herpes simplex virus type 1 sequences representing the whole genome. J Virol (1981) 5.66
Outcome of acetaminophen overdose in pediatric patients and factors contributing to hepatotoxicity. J Pediatr (1997) 5.47
Factors Affecting Germicidal Efficiency of Chlorine and Chloramine. Am J Public Health Nations Health (1944) 5.43
Regulation of even-skipped stripe 2 in the Drosophila embryo. EMBO J (1992) 4.63
Divergent homeo box proteins recognize similar DNA sequences in Drosophila. Nature (1988) 4.63
Nitrogen Availability as an Aid in the Differentiation of Bacteria in the Coli-Aerogenes Group. J Bacteriol (1938) 4.59
Role of the eaeA gene in experimental enteropathogenic Escherichia coli infection. J Clin Invest (1993) 4.53
Volunteer studies of deletion mutants of Vibrio cholerae O1 prepared by recombinant techniques. Infect Immun (1988) 4.44
Some Factors Influencing the Germicidal Efficiency of Alkalies. Am J Public Health Nations Health (1928) 4.23
Infection in total knee replacement: a retrospective review of 6489 total knee replacements. Clin Orthop Relat Res (2001) 4.15
Some Observations on the Germicidal Efficiency of Chloramine-T and Calcium Hypochlorite. J Bacteriol (1935) 4.14
Safety, immunogenicity, and efficacy of recombinant live oral cholera vaccines, CVD 103 and CVD 103-HgR. Lancet (1988) 4.12
Transcriptional and genetic analyses of the herpes simplex virus type 1 genome: coordinates 0.29 to 0.45. J Virol (1984) 4.09
Structurally distinct, stage-specific ribosomes occur in Plasmodium. Science (1987) 4.08
Antigenic variants of herpes simplex virus selected with glycoprotein-specific monoclonal antibodies. J Virol (1983) 4.04
Diaphragm function and alveolar hypoventilation. Q J Med (1976) 3.94
The Facultative Sporulating Bacteria Producing Gas from Lactose. J Bacteriol (1937) 3.93
Crystal structure of cat muscle pyruvate kinase at a resolution of 2.6 A. J Mol Biol (1979) 3.88
SOME DIFFERENTIAL REACTIONS OF COLI-LIKE BACTERIA. Am J Public Health (N Y) (1917) 3.77
The graded distribution of the dorsal morphogen is initiated by selective nuclear transport in Drosophila. Cell (1989) 3.77
Diagnosis of iron-deficiency anemia in the elderly. Am J Med (1990) 3.77
Neutralizing monoclonal antibodies specific for herpes simplex virus glycoprotein D inhibit virus penetration. J Virol (1987) 3.74
Dif, a dorsal-related gene that mediates an immune response in Drosophila. Cell (1993) 3.68
Modulation of enhancer-promoter interactions by insulators in the Drosophila embryo. Nature (1995) 3.61
Safety and immunogenicity in man of a synthetic peptide malaria vaccine against Plasmodium falciparum sporozoites. Nature (1987) 3.51
Binding affinities and cooperative interactions with bHLH activators delimit threshold responses to the dorsal gradient morphogen. Cell (1993) 3.46
The dorsal morphogen gradient regulates the mesoderm determinant twist in early Drosophila embryos. Genes Dev (1991) 3.45
The dorsal gradient morphogen regulates stripes of rhomboid expression in the presumptive neuroectoderm of the Drosophila embryo. Genes Dev (1992) 3.38
The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part I): classification of paper patients by expert opinion including uncertainty appraisal. Ann Rheum Dis (2009) 3.32
Consensus statement on the live organ donor. JAMA (2000) 3.29
Characterization and localization of the even-skipped protein of Drosophila. EMBO J (1987) 3.29
Effect of community-based interventions on high-risk drinking and alcohol-related injuries. JAMA (2000) 3.24
A vector for expressing foreign genes in the brains and hearts of transgenic mice. Genet Anal (1996) 3.18
Development of an ASAS-endorsed disease activity score (ASDAS) in patients with ankylosing spondylitis. Ann Rheum Dis (2008) 3.17
Spatial regulation of Antennapedia and bithorax gene expression by the Polycomb locus in Drosophila. Cell (1986) 3.03
Safety, infectivity, immunogenicity, and in vivo stability of two attenuated auxotrophic mutant strains of Salmonella typhi, 541Ty and 543Ty, as live oral vaccines in humans. J Clin Invest (1987) 3.03
Sequence-specific DNA-binding activities of the gap proteins encoded by hunchback and Krüppel in Drosophila. Nature (1989) 2.97
High-frequency transfer of cloned herpes simplex virus type 1 sequences to mammalian cells by protoplast fusion. Mol Cell Biol (1981) 2.97
Physical mapping of the mutation in an antigenic variant of herpes simplex virus type 1 by use of an immunoreactive plaque assay. J Virol (1983) 2.96
in vitro MORPHOGENESIS OF PHAGE P22 FROM HEADS AND BASE-PLATE PARTS. Proc Natl Acad Sci U S A (1967) 2.93
Regulation of a segmentation stripe by overlapping activators and repressors in the Drosophila embryo. Science (1991) 2.90
Ipsilateral breast tumor recurrence postlumpectomy is predictive of subsequent mortality: results from a randomized trial. Investigators of the Ontario Clinical Oncology Group. Int J Radiat Oncol Biol Phys (1994) 2.86
International ASAS consensus statement for the use of anti-tumour necrosis factor agents in patients with ankylosing spondylitis. Ann Rheum Dis (2003) 2.85
The dorsal morphogen is a sequence-specific DNA-binding protein that interacts with a long-range repression element in Drosophila. Cell (1991) 2.85
Herpes simplex virus type 1 glycoprotein C-negative mutants exhibit multiple phenotypes, including secretion of truncated glycoproteins. J Virol (1984) 2.84
dorsal-twist interactions establish snail expression in the presumptive mesoderm of the Drosophila embryo. Genes Dev (1992) 2.76
The biochemical basis of nitroblue tetrazolium reduction in normal human and chronic granulomatous disease polymorphonuclear leukocytes. Blood (1976) 2.76
The eve stripe 2 enhancer employs multiple modes of transcriptional synergy. Development (1996) 2.74
Brain spectrin, a membrane-associated protein related in structure and function to erythrocyte spectrin. Nature (1982) 2.74
Prospective study of outcome in antenatally diagnosed renal pelvis dilatation. Arch Dis Child Fetal Neonatal Ed (1999) 2.73
Fatal injuries to bicyclists: the experience of Dade County, Florida. J Trauma (1983) 2.73
Oral immunization with urease and Escherichia coli heat-labile enterotoxin is safe and immunogenic in Helicobacter pylori-infected adults. Gastroenterology (1999) 2.72
Homeo box genes of the Antennapedia and bithorax complexes of Drosophila. Cell (1985) 2.68
Transcriptional control signals of a herpes simplex virus type 1 late (gamma 2) gene lie within bases -34 to +124 relative to the 5' terminus of the mRNA. Mol Cell Biol (1986) 2.65
Genetic linkage of hyper-IgE syndrome to chromosome 4. Am J Hum Genet (1999) 2.63
Transcriptional regulation of a pair-rule stripe in Drosophila. Genes Dev (1991) 2.63
Interaction of short-range repressors with Drosophila CtBP in the embryo. Science (1998) 2.61
Ankyrin and spectrin associate with voltage-dependent sodium channels in brain. Nature (1988) 2.60
RNA synthesis by vesicular stomatitis virus and a small plaque mutant: effects of cycloheximide. J Virol (1973) 2.58
The pseudorabies virus gII gene is closely related to the gB glycoprotein gene of herpes simplex virus. J Virol (1987) 2.58
Rapid identification of nonessential genes of herpes simplex virus type 1 by Tn5 mutagenesis. Science (1987) 2.57
Local inhibition and long-range enhancement of Dpp signal transduction by Sog. Nature (1999) 2.56
Establishment of the mesoderm-neuroectoderm boundary in the Drosophila embryo. Science (1991) 2.56
Spatial distribution of Antennapedia transcripts during Drosophila development. EMBO J (1983) 2.50
Manufacturing DNA microarrays of high spot homogeneity and reduced background signal. Nucleic Acids Res (2001) 2.50
A randomized trial to assess the efficacy of surgery in addition to radiotherapy in patients with a single cerebral metastasis. Cancer (1996) 2.49
Fulminating vibrio parahemolyticus septicemia. A syndrome of erythemia multiforme, hemolytic anemia, and hypotension. Arch Intern Med (1974) 2.46
Regulation of two pair-rule stripes by a single enhancer in the Drosophila embryo. Dev Biol (1996) 2.42
The role of superoxide anion and hydrogen peroxide in phagocytosis-associated oxidative metabolic reactions. J Clin Invest (1975) 2.40
Different core promoters possess distinct regulatory activities in the Drosophila embryo. Genes Dev (1998) 2.38
Characterization of a notochord-specific enhancer from the Brachyury promoter region of the ascidian, Ciona intestinalis. Development (1997) 2.38
Short-range transcriptional repressors mediate both quenching and direct repression within complex loci in Drosophila. Genes Dev (1996) 2.36
Autoregulatory and gap gene response elements of the even-skipped promoter of Drosophila. EMBO J (1989) 2.36
Primary prevention of heart disease and stroke: a simplified approach to estimating risk of events and making drug treatment decisions. CMAJ (1997) 2.30
High frequency of antimicrobial resistance in human fecal flora. Antimicrob Agents Chemother (1988) 2.30
Changes in bone mineral content in male athletes. Mechanisms of action and intervention effects. JAMA (1996) 2.29
Phase I clinical trial of i.v. ascorbic acid in advanced malignancy. Ann Oncol (2008) 2.27
Spatially regulated expression of homeotic genes in Drosophila. Science (1985) 2.25
DIFFERENTIATION OF HUMAN AND SOIL STRAINS OF THE AEROGENES SECTION OF THE COLON GROUP. Am J Public Health (N Y) (1924) 2.25
Short-range repression permits multiple enhancers to function autonomously within a complex promoter. Genes Dev (1994) 2.24
Comparison of the safety and immunogenicity of delta aroC delta aroD and delta cya delta crp Salmonella typhi strains in adult volunteers. Infect Immun (1992) 2.23
Baseline staging tests in primary breast cancer: a practice guideline. CMAJ (2001) 2.22
Complementary patterns of even-skipped and fushi tarazu expression involve their differential regulation by a common set of segmentation genes in Drosophila. Genes Dev (1987) 2.22
dCtBP mediates transcriptional repression by Knirps, Krüppel and Snail in the Drosophila embryo. EMBO J (1998) 2.22
Hydrogen Sulfide Production as a Differential Test in the Colon Group. J Bacteriol (1936) 2.22
Supplemental social services improve outcomes in public addiction treatment. Addiction (1998) 2.21
First update of the international ASAS consensus statement for the use of anti-TNF agents in patients with ankylosing spondylitis. Ann Rheum Dis (2005) 2.21