Published in Crit Care on June 11, 2009
Effects of a fish oil containing lipid emulsion on plasma phospholipid fatty acids, inflammatory markers, and clinical outcomes in septic patients: a randomized, controlled clinical trial. Crit Care (2010) 1.47
Trauma equals danger--damage control by the immune system. J Leukoc Biol (2012) 1.15
Regulatory T cells suppress antigen-driven CD4 T cell reactivity following injury. J Leukoc Biol (2010) 0.90
Cytokines and metabolic patterns in pediatric patients with critical illness. Clin Dev Immunol (2010) 0.81
Local inflammation in fracture hematoma: results from a combined trauma model in pigs. Mediators Inflamm (2015) 0.80
Catecholamines, steroids and immune alterations in ischemic stroke and other acute diseases. Aging Dis (2014) 0.78
Bone Components Downregulate Expression of Toll-Like Receptor 4 on the Surface of Human Monocytic U937 Cells: A Cell Model for Postfracture Immune Dysfunction. Mediators Inflamm (2015) 0.76
Depressed Monocytic Activity may be a Predictor for Sepsis. J Lab Physicians (2015) 0.75
Prehospital immune responses and development of multiple organ dysfunction syndrome following traumatic injury: A prospective cohort study. PLoS Med (2017) 0.75
The danger model: a renewed sense of self. Science (2002) 13.85
Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome. Crit Care Med (1995) 10.29
Anti-inflammatory cytokines. Chest (2000) 4.74
Detection of intracellular cytokines by flow cytometry. J Immunol Methods (1993) 4.54
Multiple organ failure. Pathophysiology and potential future therapy. Ann Surg (1992) 4.50
Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies. J Immunol Methods (1995) 3.54
Bench-to-bedside review: endotoxin tolerance as a model of leukocyte reprogramming in sepsis. Crit Care (2006) 3.19
Effects of accidental trauma on cytokine and endotoxin production. Crit Care Med (1993) 2.67
Patterns of cytokine evolution (tumor necrosis factor-alpha and interleukin-6) after septic shock, hemorrhagic shock, and severe trauma. Crit Care Med (1997) 2.58
Major secondary surgery in blunt trauma patients and perioperative cytokine liberation: determination of the clinical relevance of biochemical markers. J Trauma (2001) 2.06
T-cell reactivity and its predictive role in immunosuppression after burns. Crit Care Med (1999) 1.76
Clinical aspects: from systemic inflammation to 'immunoparalysis'. Chem Immunol (2000) 1.73
Validation of postinjury multiple organ failure scores. Shock (2009) 1.64
Early versus late onset of multiple organ failure is associated with differing patterns of plasma cytokine biomarker expression and outcome after severe trauma. Shock (2007) 1.55
Mitochondrial membrane potential and apoptosis peripheral blood monocytes in severe human sepsis. Am J Respir Crit Care Med (2001) 1.41
Cytokines in patients with polytrauma. Clin Orthop Relat Res (2004) 1.19
Early detection of increased tumour necrosis factor alpha (TNFalpha) and soluble TNF receptor protein plasma levels after trauma reveals associations with the clinical course. Acta Anaesthesiol Scand (2001) 1.16
Plasma pro- and anti-inflammatory cytokine levels and outcome prediction in unselected critically ill patients. Cytokine (2008) 1.16
Depressed interleukin-12-producing activity by monocytes correlates with adverse clinical course and a shift toward Th2-type lymphocyte pattern in severely injured male trauma patients. Crit Care Med (2003) 1.15
Indicators of the posttraumatic inflammatory response correlate with organ failure in patients with multiple injuries. J Trauma (1997) 1.14
Cytokine, complement, and endotoxin profiles associated with the development of the adult respiratory distress syndrome after severe injury. Crit Care Med (1994) 1.14
The impact of endogenous triggers on trauma-associated inflammation. Curr Opin Crit Care (2006) 1.13
Toll-like receptor-mediated tumor necrosis factor and interleukin-10 production differ during systemic inflammation. Am J Respir Crit Care Med (2003) 1.11
Cytokines and plasminogen activator inhibitor-1 in posttrauma disseminated intravascular coagulation: relationship to multiple organ dysfunction syndrome. Crit Care Med (1995) 1.04
The immune response to trauma. Semin Pediatr Surg (1995) 1.01
Influence of surgical intervention in the immune response of severely injured patients. Intensive Care Med (2003) 1.01
Effect of granulocyte-macrophage colony-stimulating factor on the immune response of circulating monocytes after severe trauma. Crit Care Med (2003) 1.00
Cytokines and adhesion molecules in elective and accidental trauma-related ischemia/reperfusion. J Trauma (1998) 0.98
Use of intracellular cytokine staining and bacterial superantigen to document suppression of the adaptive immune system in injured patients. Ann Surg (2003) 0.94
Functional analysis of monocyte activity through synthesis patterns of proinflammatory cytokines and neopterin in patients in surgical intensive care. Surgery (1992) 0.93
Kinetics of circulating adhesion molecules and chemokines after mechanical trauma and burns. Eur J Surg (1996) 0.90
Levels of antibodies to endotoxin and cytokine release in patients with severe trauma: does posttraumatic dysergy contribute to organ failure? J Trauma (1999) 0.85
Mediators in polytrauma--pathophysiological significance and clinical relevance. Langenbecks Arch Surg (1998) 0.83
Analysis of N-terminal pro-B-type natriuretic peptide and cardiac index in multiple injured patients: a prospective cohort study. Crit Care (2008) 0.82
Analysis of intracellular cytokines using flowcytometry. Methods Cell Sci (2002) 0.77
Serum S-100B and interleukin-8 as predictive markers for comparative neurologic outcome analysis of patients after cardiac arrest and severe traumatic brain injury. Crit Care Med (2002) 2.42
MMP-2, MT1-MMP, and TIMP-2 are essential for the invasive capacity of human mesenchymal stem cells: differential regulation by inflammatory cytokines. Blood (2006) 2.24
Measures, markers, and mediators: toward a staging system for clinical sepsis. A report of the Fifth Toronto Sepsis Roundtable, Toronto, Ontario, Canada, October 25-26, 2000. Crit Care Med (2003) 2.01
Nonmyeloablative stem cell therapy enhances microcirculation and tissue regeneration in murine inflammatory bowel disease. Gastroenterology (2006) 1.98
Effect of long-term and high-dose antithrombin supplementation on coagulation and fibrinolysis in patients with severe sepsis. Crit Care Med (2004) 1.66
Immediate S-100B and neuron-specific enolase plasma measurements for rapid evaluation of primary brain damage in alcohol-intoxicated, minor head-injured patients. Shock (2002) 1.55
Susceptibility of automated external defibrillators to train overhead lines and metro third rails. Resuscitation (2004) 1.54
Clinical review: immunodepression in the surgical patient and increased susceptibility to infection. Crit Care (2002) 1.54
Bilateral lavage with diluted surfactant improves lung function after unilateral lung contusion in pigs. Crit Care Med (2005) 1.51
Increased activation of the transcription factor c-Jun by MAP kinases in monocytes of multiple trauma patients is associated with adverse outcome and mass transfusion. J Surg Res (2012) 1.43
Inflammatory mediators are altered in the acute phase of posttraumatic complex regional pain syndrome. Clin J Pain (2006) 1.42
The Wnt signal transduction pathway in stem cells and cancer cells: influence on cellular invasion. Stem Cell Rev (2007) 1.41
5-Aminoisoquinolinone, a novel inhibitor of poly(adenosine disphosphate-ribose) polymerase, reduces microvascular liver injury but not mortality rate after hepatic ischemia-reperfusion. Crit Care Med (2004) 1.40
Analysis of tissue distribution of TNF-alpha, TNF-alpha-receptors, and the activating TNF-alpha-converting enzyme suggests activation of the TNF-alpha system in the aging intervertebral disc. Ann N Y Acad Sci (2007) 1.33
Wnt signaling regulates the invasion capacity of human mesenchymal stem cells. Stem Cells (2006) 1.21
Outcome analysis following removal of locking plate fixation of the proximal humerus. BMC Musculoskelet Disord (2008) 1.21
The chemopreventive polyphenol Curcumin prevents hematogenous breast cancer metastases in immunodeficient mice. Cell Physiol Biochem (2007) 1.21
Balloon osteoplasty--a new technique for minimally invasive reduction and stabilisation of Hill-Sachs lesions of the humeral head: a cadaver study. Int Orthop (2012) 1.20
Whole-body CT in haemodynamically unstable severely injured patients--a retrospective, multicentre study. PLoS One (2013) 1.19
Curcumin downregulates the inflammatory cytokines CXCL1 and -2 in breast cancer cells via NFkappaB. Carcinogenesis (2007) 1.15
Sulfur mustard research--strategies for the development of improved medical therapy. Eplasty (2008) 1.14
Comparison of intraosseous versus central venous vascular access in adults under resuscitation in the emergency department with inaccessible peripheral veins. Resuscitation (2011) 1.14
The impact of endogenous triggers on trauma-associated inflammation. Curr Opin Crit Care (2006) 1.13
RGD-dependent binding of procathepsin X to integrin alphavbeta3 mediates cell-adhesive properties. J Biol Chem (2006) 1.11
The prognostic value of polymorphonuclear leukocyte elastase in patients with primary breast cancer. Cancer Res (2003) 1.11
Human mesenchymal stem cells at the single-cell level: simultaneous seven-colour immunofluorescence. J Anat (2007) 1.10
Tissue inhibitor of metalloproteinase-1 (TIMP-1) regulates mesenchymal stem cells through let-7f microRNA and Wnt/β-catenin signaling. Proc Natl Acad Sci U S A (2012) 1.09
Mono- versus polyaxial locking plates in distal femur fractures: a prospective randomized multicentre clinical trial. Int Orthop (2013) 1.07
Extracranial sources of S100B do not affect serum levels. PLoS One (2010) 1.06
Mutation of tyrosine in the conserved NPXXY sequence leads to constitutive phosphorylation and internalization, but not signaling, of the human B2 bradykinin receptor. J Biol Chem (2004) 1.01
Nonviral genetic modification mediates effective transgene expression and functional RNA interference in human mesenchymal stem cells. J Gene Med (2005) 1.01
Prognostic impact of matrix metalloproteinase-9 in operable non-small cell lung cancer. Int J Cancer (2003) 0.99
Consistency of long-term outcome of acute Rockwood grade III acromioclavicular joint separations after K-wire transfixation. J Trauma (2009) 0.99
Genome-wide monocytic mRNA expression in polytrauma patients for identification of clinical outcome. Shock (2005) 0.97
Cell density-dependent regulation of matrix metalloproteinase and TIMP expression in differently tumorigenic breast cancer cell lines. Exp Cell Res (2005) 0.97
Comparison of two intraosseous access devices in adult patients under resuscitation in the emergency department: A prospective, randomized study. Resuscitation (2010) 0.95
Monoaxial versus polyaxial screw insertion in angular stable plate fixation of proximal humeral fractures: radiographic analysis of a prospective randomized study. J Trauma (2010) 0.95
Intrathecal and systemic concentration of NT-proBNP in patients with severe traumatic brain injury. J Neurotrauma (2006) 0.94
The calpastatin-derived calpain inhibitor CP1B reduces mRNA expression of matrix metalloproteinase-2 and -9 and invasion by leukemic THP-1 cells. Biol Chem (2003) 0.93
Platelet adhesion mediated by fibrinogen-intercelllular adhesion molecule-1 binding induces tissue injury in the postischemic liver in vivo. Transplantation (2002) 0.92
Systemic ubiquitin release after blunt trauma and burns: association with injury severity, posttraumatic complications, and survival. J Trauma (2008) 0.91
Hypothermia for prediction of death in severely injured blunt trauma patients. Shock (2012) 0.91
Dissecting the impact of Frizzled receptors in Wnt/β-catenin signaling of human mesenchymal stem cells. Biol Chem (2012) 0.91
Wnt signalling in mouse mesenchymal stem cells: impact on proliferation, invasion and MMP expression. J Cell Mol Med (2008) 0.90
Modulation of autocrine TNF-alpha-stimulated matrix metalloproteinase 9 (MMP-9) expression by mitogen-activated protein kinases in THP-1 monocytic cells. Biol Chem (2006) 0.90
Effect of stress doses of hydrocortisone on S-100B vs. interleukin-8 and polymorphonuclear elastase levels in human septic shock. Clin Chem Lab Med (2005) 0.90
Revascularization of transplanted adipose tissue: a study in the dorsal skinfold chamber of hamsters. Ann Plast Surg (2002) 0.90
Cellular senescence induced by cathepsin X downregulation. Eur J Cell Biol (2011) 0.89
Poly(ADP-ribose) polymerase triggers the microvascular mechanisms of hepatic ischemia-reperfusion injury. Am J Physiol Gastrointest Liver Physiol (2002) 0.89
Perioperative recombinant human granulocyte colony-stimulating factor (Filgrastim) treatment prevents immunoinflammatory dysfunction associated with major surgery. Ann Surg (2004) 0.88
Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells: (auto-)catalytic activation and resistance to inhibition by TIMP-1. Biochem J (2007) 0.88
Matrix metalloproteinase-9 expression and release from skin fibroblasts interacting with keratinocytes: Upregulation in response to sulphur mustard. Toxicology (2008) 0.88
Balloon osteoplasty--a new technique for reduction and stabilisation of impression fractures in the tibial plateau: a cadaver study and first clinical application. Int Orthop (2012) 0.87
The role of biological sex in severely traumatized patients on outcomes: a matched-pair analysis. Ann Surg (2015) 0.86
Human osteoblast-derived factors induce early osteogenic markers in human mesenchymal stem cells. Tissue Eng Part A (2009) 0.86
Platelet-endothelial cell interactions during hepatic ischemia-reperfusion in vivo: a systematic analysis. Microvasc Res (2003) 0.86
The role of helix 8 and of the cytosolic C-termini in the internalization and signal transduction of B(1) and B(2) bradykinin receptors. FEBS J (2005) 0.86
Matrix metalloproteinases in cancer: comparison of known and novel aspects of their inhibition as a therapeutic approach. Expert Rev Anticancer Ther (2005) 0.86
Circulating mediators and organ function in patients undergoing planned relaparotomy vs conventional surgical therapy in severe secondary peritonitis. Arch Surg (2002) 0.86
P-selectin mediates platelet-endothelial cell interactions and reperfusion injury in the mouse liver in vivo. Shock (2002) 0.85
Sulfur mustard induces differentiation in human primary keratinocytes: opposite roles of p38 and ERK1/2 MAPK. Toxicol Lett (2011) 0.85
Lineage infidelity and expression of melanocytic markers in human breast cancer. Int J Oncol (2008) 0.85
The Munich Shoulder Questionnaire (MSQ): development and validation of an effective patient-reported tool for outcome measurement and patient safety in shoulder surgery. Patient Saf Surg (2012) 0.84
The effects of a plant proteinase inhibitor from Enterolobium contortisiliquum on human tumor cell lines. Biol Chem (2011) 0.84
Functional characterization of cultured keratinocytes after acute cutaneous burn injury. PLoS One (2012) 0.84
Overexpression of the ATP binding cassette gene ABCA1 determines resistance to Curcumin in M14 melanoma cells. Mol Cancer (2009) 0.84
Predictive relevance of clinical scores and inflammatory parameters in secondary peritonitis. Bull Soc Sci Med Grand Duche Luxemb (2011) 0.83
Expression levels strongly affect ligand-induced sequestration of B2 bradykinin receptors in transfected cells. Am J Physiol Heart Circ Physiol (2003) 0.83
Reporter gene HEK 293 cells and WNT/Frizzled fusion proteins as tools to study WNT signaling pathways. Biol Chem (2011) 0.83
Rapid measurement of S-100B serum protein levels by Elecsys S100 immunoassay in patients undergoing carotid artery stenting or endarterectomy. Clin Biochem (2006) 0.83
Assessment of early brain damage in carotid endarterectomy: evaluation of S-100B serum levels and somatosensory evoked potentials in a pilot study. World J Surg (2002) 0.82
Identification of calpain cleavage sites in the G1 cyclin-dependent kinase inhibitor p19(INK4d). Biol Chem (2006) 0.82
Transcriptional control of cell density dependent regulation of matrix metalloproteinase and TIMP expression in breast cancer cell lines. Thromb Haemost (2005) 0.82
Double intramedullary cortical button versus suture anchors for distal biceps tendon repair: a biomechanical comparison. Knee Surg Sports Traumatol Arthrosc (2013) 0.82
Analysis of N-terminal pro-B-type natriuretic peptide and cardiac index in multiple injured patients: a prospective cohort study. Crit Care (2008) 0.82
Measurement of S-100B for risk classification of victims sustaining minor head injury--first pilot study in Brazil. Clinics (Sao Paulo) (2006) 0.82
How to leverage an endogenous immune defense mechanism: the example of granulocyte colony-stimulating factor. Crit Care Med (2003) 0.81
Synovial chondromatosis of the long biceps tendon sheath in a child: a case report and review of the literature. J Shoulder Elbow Surg (2008) 0.81
Identification of a signal transduction pathway that regulates MMP-9 mRNA expression in glomerular injury. Biol Chem (2002) 0.81
Chronic left heart catheterization for microvascular blood flow determination in the rabbit: a minimally invasive technique using specially designed port devices. J Surg Res (2002) 0.81
High-dose aprotinin reduces activation of hemostasis, allogeneic blood requirement, and duration of postoperative ventilation in pediatric cardiac surgery. Ann Thorac Surg (2003) 0.80
An enzyme-linked immunosorbent assay for human cathepsin X, a potential new inflammatory marker. J Immunol Methods (2005) 0.80
Significance of Elecsys S100 immunoassay for real-time assessment of traumatic brain damage in multiple trauma patients. Clin Chem Lab Med (2006) 0.80
Alanine screening of the intracellular loops of the human bradykinin B receptor--effects on receptor maintenance, G protein activation and internalization. FEBS J (2009) 0.80
Enhanced expression and activation of major matrix metalloproteinases in distinct topographic areas of invasive breast carcinomas. Int J Oncol (2005) 0.80
Dehydroepiandrosterone restores depressed peripheral blood mononuclear cell function following major abdominal surgery via the estrogen receptors. Crit Care Med (2005) 0.80
A consensus statement on empiric therapy for suspected gram-positive infections in surgical patients. Am J Surg (2004) 0.80