Published in Structure on June 10, 2009
Structural basis for scaffolding-mediated assembly and maturation of a dsDNA virus. Proc Natl Acad Sci U S A (2011) 2.03
A common evolutionary origin for tailed-bacteriophage functional modules and bacterial machineries. Microbiol Mol Biol Rev (2011) 1.92
Three-dimensional structure of a viral genome-delivery portal vertex. Nat Struct Mol Biol (2011) 1.71
P22 coat protein structures reveal a novel mechanism for capsid maturation: stability without auxiliary proteins or chemical crosslinks. Structure (2010) 1.44
'Let the phage do the work': using the phage P22 coat protein structures as a framework to understand its folding and assembly mutants. Virology (2010) 1.32
Peering down the barrel of a bacteriophage portal: the genome packaging and release valve in p22. Structure (2011) 1.28
Virus maturation. Annu Rev Biophys (2012) 1.20
Visualization of uncorrelated, tandem symmetry mismatches in the internal genome packaging apparatus of bacteriophage T7. Proc Natl Acad Sci U S A (2013) 1.19
Cryomesh: a new substrate for cryo-electron microscopy. Microsc Microanal (2010) 1.11
Bacteriophage assembly. Viruses (2011) 1.07
Structural evolution of the P22-like phages: comparison of Sf6 and P22 procapsid and virion architectures. Virology (2012) 1.04
Visualizing a complete Siphoviridae member by single-particle electron microscopy: the structure of lactococcal phage TP901-1. J Virol (2012) 1.01
Tailspike interactions with lipopolysaccharide effect DNA ejection from phage P22 particles in vitro. J Biol Chem (2010) 0.94
An automated procedure for detecting protein folds from sub-nanometer resolution electron density. J Struct Biol (2009) 0.90
Atomic structure of bacteriophage Sf6 tail needle knob. J Biol Chem (2011) 0.89
Viral infection modulation and neutralization by camelid nanobodies. Proc Natl Acad Sci U S A (2013) 0.88
Crystallization of the nonameric small terminase subunit of bacteriophage P22. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.87
Architecture of viral genome-delivery molecular machines. Curr Opin Struct Biol (2013) 0.85
Identification of structural and morphogenesis genes of Pseudoalteromonas phage φRIO-1 and placement within the evolutionary history of Podoviridae. Virology (2015) 0.79
Acquiring Structural Information on Virus Particles with Charge Detection Mass Spectrometry. J Am Soc Mass Spectrom (2016) 0.79
Bacteriophage P22 ejects all of its internal proteins before its genome. Virology (2015) 0.79
The host outer membrane proteins OmpA and OmpC are associated with the Shigella phage Sf6 virion. Virology (2010) 0.78
Structure of a Bacterial Virus DNA-Injection Protein Complex Reveals a Decameric Assembly with a Constricted Molecular Channel. PLoS One (2016) 0.76
Structural Plasticity of the Protein Plug That Traps Newly Packaged Genomes in Podoviridae Virions. J Biol Chem (2015) 0.76
Genetic analysis of structural proteins in the adsorption apparatus of bacteriophage epsilon 15. World J Virol (2013) 0.76
Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation. Nat Commun (2017) 0.75
Localization of the Houdinisome (Ejection Proteins) inside the Bacteriophage P22 Virion by Bubblegram Imaging. MBio (2016) 0.75
Coot: model-building tools for molecular graphics. Acta Crystallogr D Biol Crystallogr (2004) 227.01
EMAN: semiautomated software for high-resolution single-particle reconstructions. J Struct Biol (1999) 27.52
SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields. J Struct Biol (1996) 22.89
Protein structure prediction using Rosetta. Methods Enzymol (2004) 12.05
Automated molecular microscopy: the new Leginon system. J Struct Biol (2005) 10.00
Visualizing density maps with UCSF Chimera. J Struct Biol (2006) 5.75
Appion: an integrated, database-driven pipeline to facilitate EM image processing. J Struct Biol (2009) 5.71
Structure of the bacteriophage phi29 DNA packaging motor. Nature (2000) 5.25
DNA packaging by the double-stranded DNA bacteriophages. Cell (1980) 3.92
Structure of epsilon15 bacteriophage reveals genome organization and DNA packaging/injection apparatus. Nature (2006) 3.73
DoG Picker and TiltPicker: software tools to facilitate particle selection in single particle electron microscopy. J Struct Biol (2009) 3.71
The UL6 gene product forms the portal for entry of DNA into the herpes simplex virus capsid. J Virol (2001) 3.65
The structure of an infectious P22 virion shows the signal for headful DNA packaging. Science (2006) 3.33
Protein structure fitting and refinement guided by cryo-EM density. Structure (2008) 3.12
The tail structure of bacteriophage T4 and its mechanism of contraction. Nat Struct Mol Biol (2005) 2.82
Detailed architecture of a DNA translocating machine: the high-resolution structure of the bacteriophage phi29 connector particle. J Mol Biol (2002) 2.75
FindEM--a fast, efficient program for automatic selection of particles from electron micrographs. J Struct Biol (2004) 2.74
ACE: automated CTF estimation. Ultramicroscopy (2005) 2.62
Structural framework for DNA translocation via the viral portal protein. EMBO J (2007) 2.58
The portal protein of bacteriophage SPP1: a DNA pump with 13-fold symmetry. EMBO J (1993) 2.55
Ab initio resolution measurement for single particle structures. J Struct Biol (2006) 2.53
Tailed bacteriophages: the order caudovirales. Adv Virus Res (1998) 2.47
Structure and polymorphism of the UL6 portal protein of herpes simplex virus type 1. J Virol (2004) 2.35
DNA poised for release in bacteriophage phi29. Structure (2008) 2.29
Cryo-EM asymmetric reconstruction of bacteriophage P22 reveals organization of its DNA packaging and infecting machinery. Structure (2006) 2.26
Structure of a viral DNA gatekeeper at 10 A resolution by cryo-electron microscopy. EMBO J (2003) 2.16
Structural changes of bacteriophage phi29 upon DNA packaging and release. EMBO J (2006) 1.90
Maturation of phage T7 involves structural modification of both shell and inner core components. EMBO J (2005) 1.89
Structure of bacteriophage SPP1 tail reveals trigger for DNA ejection. EMBO J (2007) 1.81
DNA packaging and delivery machines in tailed bacteriophages. Curr Opin Struct Biol (2007) 1.79
Highly discriminatory binding of capsid-cementing proteins in bacteriophage L. Structure (2006) 1.71
Crystal structure of phage P22 tailspike protein complexed with Salmonella sp. O-antigen receptors. Proc Natl Acad Sci U S A (1996) 1.66
Structural organisation of the head-to-tail interface of a bacterial virus. J Mol Biol (2001) 1.63
Structure of the connector of bacteriophage T7 at 8A resolution: structural homologies of a basic component of a DNA translocating machinery. J Mol Biol (2005) 1.63
Steps in the stabilization of newly packaged DNA during phage P22 morphogenesis. J Mol Biol (1984) 1.51
Purification and organization of the gene 1 portal protein required for phage P22 DNA packaging. Biochemistry (1988) 1.50
The structures of bacteriophages K1E and K1-5 explain processive degradation of polysaccharide capsules and evolution of new host specificities. J Mol Biol (2007) 1.48
Anatomy of a lactococcal phage tail. J Bacteriol (2006) 1.46
Identification of a gene in Bacillus subtilis bacteriophage SPP1 determining the amount of packaged DNA. J Mol Biol (1992) 1.41
Bacteriophage P22 portal protein is part of the gauge that regulates packing density of intravirion DNA. J Mol Biol (1992) 1.38
Assembly architecture and DNA binding of the bacteriophage P22 terminase small subunit. J Mol Biol (2008) 1.37
Improved methods for determination of rotational symmetries in macromolecules. Ultramicroscopy (1995) 1.26
Three-dimensional structure of the bacteriophage P22 tail machine. EMBO J (2005) 1.25
Structure of phage P22 cell envelope–penetrating needle. Nat Struct Mol Biol (2007) 1.24
Preliminary crystallographic analysis of the bacteriophage P22 portal protein. J Struct Biol (2002) 1.20
Enzymic and molecular properties of base-plate parts of bacteriophage P22. Eur J Biochem (1976) 1.20
Three-dimensional analysis of single particles by electron microscopy: sample preparation and data acquisition. Methods Mol Biol (2006) 1.15
Domain organization and polarity of tail needle GP26 in the portal vertex structure of bacteriophage P22. J Mol Biol (2007) 1.13
The portal protein plays essential roles at different steps of the SPP1 DNA packaging process. Virology (2004) 1.10
Binding-induced stabilization and assembly of the phage P22 tail accessory factor gp4. J Mol Biol (2006) 1.08
Bacteriophage SPO1 structure and morphogenesis. I. Tail structure and length regulation. J Virol (1983) 1.05
The high-resolution functional map of bacteriophage SPP1 portal protein. Mol Microbiol (2004) 1.03
A conformational switch in bacteriophage p22 portal protein primes genome injection. Mol Cell (2008) 1.03
Macromolecular mass spectrometry and electron microscopy as complementary tools for investigation of the heterogeneity of bacteriophage portal assemblies. J Struct Biol (2006) 1.00
A defined in vitro system for DNA packaging by the bacteriophage SPP1: insights into the headful packaging mechanism. J Mol Biol (2005) 0.99
Structural plasticity of the phage P22 tail needle gp26 probed with xenon gas. Protein Sci (2009) 0.98
Structure of the central hub of bacteriophage Mu baseplate determined by X-ray crystallography of gp44. J Mol Biol (2005) 0.96
Morphogenesis of the tail of bacteriophage lambda. III. Morphogenetic pathway. J Mol Biol (1975) 0.95
Intragenic suppression of a capsid assembly-defective P22 tailspike mutation. Genetics (1990) 0.87
Purified membrane-containing procapsids of bacteriophage PRD1 package the viral genome. J Mol Biol (2009) 0.87
Structural transformations accompanying the assembly of bacteriophage P22 portal protein rings in vitro. J Biol Chem (2000) 0.87
The gpQ portal protein of bacteriophage P2 forms dodecameric connectors in crystals. J Struct Biol (2006) 0.87
Probing conserved helical modules of portal complexes by mass spectrometry-based hydrogen/deuterium exchange. J Mol Biol (2008) 0.86
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature (2010) 23.55
Automated molecular microscopy: the new Leginon system. J Struct Biol (2005) 10.00
Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature (2011) 7.20
Effect of prize-based incentives on outcomes in stimulant abusers in outpatient psychosocial treatment programs: a national drug abuse treatment clinical trials network study. Arch Gen Psychiatry (2005) 6.97
BMP4 initiates human embryonic stem cell differentiation to trophoblast. Nat Biotechnol (2002) 6.20
Appion: an integrated, database-driven pipeline to facilitate EM image processing. J Struct Biol (2009) 5.71
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48
A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield. Science (2011) 5.44
Effects of lower-cost incentives on stimulant abstinence in methadone maintenance treatment: a National Drug Abuse Treatment Clinical Trials Network study. Arch Gen Psychiatry (2006) 4.64
Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer. Science (2013) 4.61
Outcome of the first electron microscopy validation task force meeting. Structure (2012) 4.35
Impact of HIV infection and HAART on serum lipids in men. JAMA (2003) 4.01
The UK10K project identifies rare variants in health and disease. Nature (2015) 3.89
Highly conserved protective epitopes on influenza B viruses. Science (2012) 3.47
The structure of an infectious P22 virion shows the signal for headful DNA packaging. Science (2006) 3.33
hsa-mir-181a and hsa-mir-181b function as tumor suppressors in human glioma cells. Brain Res (2008) 3.20
Structural basis for cargo regulation of COPII coat assembly. Cell (2008) 3.15
Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120. Nat Struct Mol Biol (2013) 3.11
Comparison and evaluation of methods for liver segmentation from CT datasets. IEEE Trans Med Imaging (2009) 3.03
A gain-of-function mutation in DHT synthesis in castration-resistant prostate cancer. Cell (2013) 2.94
Characterization of circulating endothelial cells in acute myocardial infarction. Sci Transl Med (2012) 2.91
Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer. Proc Natl Acad Sci U S A (2011) 2.89
Beam-induced motion of vitrified specimen on holey carbon film. J Struct Biol (2012) 2.84
Movies of ice-embedded particles enhance resolution in electron cryo-microscopy. Structure (2012) 2.80
Coat protein fold and maturation transition of bacteriophage P22 seen at subnanometer resolutions. Nat Struct Biol (2003) 2.76
Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts. PLoS Med (2013) 2.73
Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans. PLoS Pathog (2013) 2.66
Structure of the Sec13/31 COPII coat cage. Nature (2006) 2.63
ACE: automated CTF estimation. Ultramicroscopy (2005) 2.62
Bacteriophage lambda stabilization by auxiliary protein gpD: timing, location, and mechanism of attachment determined by cryo-EM. Structure (2008) 2.62
Quantitative pharmacokinetic analysis of DCE-MRI data without an arterial input function: a reference region model. Magn Reson Imaging (2005) 2.54
Dopaminergic network differences in human impulsivity. Science (2010) 2.49
A physically transient form of silicon electronics. Science (2012) 2.47
VIPERdb: a relational database for structural virology. Nucleic Acids Res (2006) 2.46
Cross-neutralization of influenza A viruses mediated by a single antibody loop. Nature (2012) 2.44
Variation in gene expression patterns in human gastric cancers. Mol Biol Cell (2003) 2.39
VIPERdb2: an enhanced and web API enabled relational database for structural virology. Nucleic Acids Res (2008) 2.38
Key interactions in HIV-1 maturation identified by hydrogen-deuterium exchange. Nat Struct Mol Biol (2004) 2.34
Identification of novel interactions in HIV-1 capsid protein assembly by high-resolution mass spectrometry. J Mol Biol (2003) 2.32
L-A virus at 3.4 A resolution reveals particle architecture and mRNA decapping mechanism. Nat Struct Biol (2002) 2.30
Structure of an archaeal virus capsid protein reveals a common ancestry to eukaryotic and bacterial viruses. Proc Natl Acad Sci U S A (2005) 2.26
Evaluation of registration methods on thoracic CT: the EMPIRE10 challenge. IEEE Trans Med Imaging (2011) 2.24
Highly active antiretroviral therapy and cervical squamous intraepithelial lesions in human immunodeficiency virus-positive women. J Natl Cancer Inst (2004) 2.23
Nonracemic Betti base as a new chiral auxiliary: application to total syntheses of enantiopure (2S,6R)-dihydropinidine and (2S,6R)-isosolenopsins. J Org Chem (2005) 2.19
Automated cryoEM data acquisition and analysis of 284742 particles of GroEL. J Struct Biol (2006) 2.15
The structure of a thermophilic archaeal virus shows a double-stranded DNA viral capsid type that spans all domains of life. Proc Natl Acad Sci U S A (2004) 2.13
Transcriptional profiling of long non-coding RNAs and novel transcribed regions across a diverse panel of archived human cancers. Genome Biol (2012) 2.12
The refined structure of a protein catenane: the HK97 bacteriophage capsid at 3.44 A resolution. J Mol Biol (2003) 2.11
Accounting for leadtime in cohort studies: evaluating when to initiate HIV therapies. Stat Med (2004) 2.04
Irisin stimulates browning of white adipocytes through mitogen-activated protein kinase p38 MAP kinase and ERK MAP kinase signaling. Diabetes (2013) 2.02
Mesolimbic dopamine reward system hypersensitivity in individuals with psychopathic traits. Nat Neurosci (2010) 2.01
The macrophage colony-stimulating factor 1 response signature in breast carcinoma. Clin Cancer Res (2009) 2.00
Incidence of lipoatrophy and lipohypertrophy in the women's interagency HIV study. J Acquir Immune Defic Syndr (2003) 1.95
Organization of the influenza virus replication machinery. Science (2012) 1.89
Mechanism of scaffolding-assisted viral assembly. Adv Protein Chem (2003) 1.87
Landscape dynamitic change in Mu Us Desert derived from Landsat TM data. J Environ Sci (China) (2003) 1.85
Visualizing ribosome biogenesis: parallel assembly pathways for the 30S subunit. Science (2010) 1.84
Fully automated, sequential tilt-series acquisition with Leginon. J Struct Biol (2009) 1.84
Automatic particle selection: results of a comparative study. J Struct Biol (2004) 1.82
Phospholipase A2 group IIA expression in gastric adenocarcinoma is associated with prolonged survival and less frequent metastasis. Proc Natl Acad Sci U S A (2002) 1.81
An unexpected twist in viral capsid maturation. Nature (2009) 1.80
Digital cameras with designs inspired by the arthropod eye. Nature (2013) 1.77
Initial evaluation of a direct detection device detector for single particle cryo-electron microscopy. J Struct Biol (2011) 1.77
An empirical assessment of high-performing medical groups: results from a national study. Med Care Res Rev (2005) 1.75
Three-dimensional structure of a viral genome-delivery portal vertex. Nat Struct Mol Biol (2011) 1.71
Highly discriminatory binding of capsid-cementing proteins in bacteriophage L. Structure (2006) 1.71
Altered default mode network connectivity in Alzheimer's disease--a resting functional MRI and Bayesian network study. Hum Brain Mapp (2011) 1.67
New addresses on an addressable virus nanoblock; uniquely reactive Lys residues on cowpea mosaic virus. Chem Biol (2004) 1.67
Dopaminergic mechanisms of individual differences in human effort-based decision-making. J Neurosci (2012) 1.64
Natural supramolecular building blocks. Wild-type cowpea mosaic virus. Chem Biol (2002) 1.64
Prize-based contingency management does not increase gambling. Drug Alcohol Depend (2006) 1.63
Array-based comparative genomic hybridization reveals recurrent chromosomal aberrations and Jab1 as a potential target for 8q gain in hepatocellular carcinoma. Carcinogenesis (2005) 1.59
Kinetic analysis of the role of intersubunit interactions in human immunodeficiency virus type 1 capsid protein assembly in vitro. J Virol (2002) 1.55
Midbrain dopamine receptor availability is inversely associated with novelty-seeking traits in humans. J Neurosci (2008) 1.54
Unnatural amino acid incorporation into virus-like particles. Bioconjug Chem (2008) 1.54
The molecular architecture of human Dicer. Nat Struct Mol Biol (2012) 1.53
Sprouty 2, an inhibitor of mitogen-activated protein kinase signaling, is down-regulated in hepatocellular carcinoma. Cancer Res (2006) 1.52
Capsid conformational sampling in HK97 maturation visualized by X-ray crystallography and cryo-EM. Structure (2006) 1.50
Allosteric regulation of DNA cleavage and sequence-specificity through run-on oligomerization. Structure (2013) 1.49