Reducing suicidal ideation and depression in older primary care patients: 24-month outcomes of the PROSPECT study.

PubWeight™: 2.56‹?› | Rank: Top 1%

🔗 View Article (PMC 2838419)

Published in Am J Psychiatry on June 15, 2009

Authors

George S Alexopoulos1, Charles F Reynolds, Martha L Bruce, Ira R Katz, Patrick J Raue, Benoit H Mulsant, David W Oslin, Thomas Ten Have, PROSPECT Group

Author Affiliations

1: Department of Psychiatry, Weill Cornell Medical College, 21 Bloomingdale Rd., White Plains, NY 10605, USA. gsalexop@med.cornell.edu

Associated clinical trials:

Prevention of Suicide in Primary Care Elderly: Collaborative Trial (PROSPECT) | NCT00279682

Articles citing this

Usual and unusual care: existing practice control groups in randomized controlled trials of behavioral interventions. Psychosom Med (2011) 1.93

Long term effect of depression care management on mortality in older adults: follow-up of cluster randomized clinical trial in primary care. BMJ (2013) 1.91

Clinical effectiveness of integrating depression care management into medicare home health: the Depression CAREPATH Randomized trial. JAMA Intern Med (2015) 1.51

Suicide prevention in later life: a glass half full, or half empty? Am J Psychiatry (2009) 1.44

Suicide in older adults. Psychiatr Clin North Am (2011) 1.41

Care integration in the Patient Protection and Affordable Care Act: implications for behavioral health. Adm Policy Ment Health (2013) 1.23

Determinants of readiness for primary care-mental health integration (PC-MHI) in the VA Health Care System. J Gen Intern Med (2012) 1.20

Practical suicide-risk management for the busy primary care physician. Mayo Clin Proc (2011) 1.20

Geriatric depression in primary care. Psychiatr Clin North Am (2011) 1.19

A systematic review of elderly suicide prevention programs. Crisis (2011) 1.18

Early intervention to reduce the global health and economic burden of major depression in older adults. Annu Rev Public Health (2012) 1.15

A systematic review of social factors and suicidal behavior in older adulthood. Int J Environ Res Public Health (2012) 1.10

Suicide and suicidal behaviour. Lancet (2015) 1.03

Suicides in late life. Curr Psychiatry Rep (2011) 0.97

Collaborative depression care management and disparities in depression treatment and outcomes. Arch Gen Psychiatry (2011) 0.97

Low use of mental health services among older Americans with mood and anxiety disorders. Psychiatr Serv (2012) 0.94

A systematic approach to pharmacotherapy for geriatric major depression. Clin Geriatr Med (2014) 0.91

Personalised intervention for people with depression and severe COPD. Br J Psychiatry (2013) 0.91

Cognitive inhibition in older high-lethality suicide attempters. Int J Geriatr Psychiatry (2014) 0.89

Suicide risk in primary care: identification and management in older adults. Curr Psychiatry Rep (2014) 0.88

Economic inequalities in the effectiveness of a primary care intervention for depression and suicidal ideation. Epidemiology (2013) 0.85

Social inequalities in depression and suicidal ideation among older primary care patients. Soc Psychiatry Psychiatr Epidemiol (2012) 0.85

Late-life depression in the primary care setting: challenges, collaborative care, and prevention. Maturitas (2014) 0.84

A systematic review of physical illness, functional disability, and suicidal behaviour among older adults. Aging Ment Health (2015) 0.83

Efficacy of a systematic depression management program in high utilizers of primary care: a randomized trial. BMC Health Serv Res (2012) 0.82

Primary care physicians' and psychiatrists' approaches to treating mild depression. Acta Psychiatr Scand (2012) 0.82

Adapting interpersonal psychotherapy for older adults at risk for suicide. Am J Geriatr Psychiatry (2014) 0.82

Relationship between depressive symptom severity and emergency department use among low-income, depressed homebound older adults aged 50 years and older. BMC Psychiatry (2012) 0.81

Late-life depression in older African Americans: a comprehensive review of epidemiological and clinical data. Int J Geriatr Psychiatry (2012) 0.81

Self-help for binge eating disorder in primary care: a randomized controlled trial with ethnically and racially diverse obese patients. Behav Res Ther (2013) 0.81

Cognition in Late Life Depression: Treatment Considerations. Curr Treat Options Psychiatry (2014) 0.81

Cognitive remission: a novel objective for the treatment of major depression? BMC Med (2016) 0.80

The prognostic significance of subsyndromal symptoms emerging after remission of late-life depression. Psychol Med (2012) 0.78

Control strategies and suicidal ideation in older primary care patients with functional limitations. Int J Psychiatry Med (2013) 0.78

Integration of geriatric mental health screening into a primary care practice: a patient satisfaction survey. Int J Geriatr Psychiatry (2014) 0.78

Electronic protocol for suicide risk management in research participants. J Psychosom Res (2014) 0.77

Depression care management for late-life depression in China primary care: protocol for a randomized controlled trial. Trials (2011) 0.77

Anxiety symptoms in older home health care recipients: prevalence and associates. Home Health Care Serv Q (2013) 0.77

Preventing depression in later life: state of the art and science circa 2011. Psychiatr Clin North Am (2010) 0.77

Issues in research on aging and suicide. Aging Ment Health (2015) 0.77

Elderly care recipients' perceptions of treatment helpfulness for depression and the relationship with help-seeking. Clin Interv Aging (2015) 0.76

The role of physicians in advocating for a national strategy for suicide prevention. CMAJ (2011) 0.76

Suicide in older adults: the role of emotions and cognition. Curr Psychiatry Rep (2014) 0.76

Suicide Attempt Characteristics Among Veterans and Active-Duty Service Members Receiving Mental Health Services: A Pooled Data Analysis. Mil Behav Health (2015) 0.75

Prioritizing research to reduce youth suicide and suicidal behavior. Am J Prev Med (2014) 0.75

Reducing suicidal ideation and depression in older primary care patients: the oldest old and pain. Am J Psychiatry (2010) 0.75

Feasibility of integrating mental health screening and services into routine elder abuse practice to improve client outcomes. J Elder Abuse Negl (2015) 0.75

Resilience Protected against Suicidal Behavior for Men But Not Women in a Community Sample of Older Adults in Korea. Front Psychol (2017) 0.75

Using the Interpersonal Theory of Suicide to Inform Interpersonal Psychotherapy with a Suicidal Older Adult. Clin Case Stud (2012) 0.75

Integration of suicide prevention program into primary health care network: a field clinical trial in Iran. Med J Islam Repub Iran (2015) 0.75

Going around in a Circle: A Norwegian Study of Suicidal Experiences in Old Age. Nurs Res Pract (2014) 0.75

Protective factors against suicide among young-old Chinese outpatients. BMC Public Health (2014) 0.75

Effect of Problem-Solving Therapy on Depressed Low-Income Homebound Older Adults' Death/Suicidal Ideation and Hopelessness. Suicide Life Threat Behav (2015) 0.75

Treatment Emergent Suicidal Ideation in depressed older adults. Int J Geriatr Psychiatry (2016) 0.75

An observational study of the impact of service use on suicidality among adults with mental disorders. Inj Epidemiol (2014) 0.75

Mini Review of Integrated Care and Implications for Advanced Practice Nurse Role. Open Nurs J (2016) 0.75

Models of care for late-life depression of the medically ill: examples from chronic obstructive pulmonary disease and stroke. Am J Geriatr Psychiatry (2014) 0.75

Stability of remission rates in a 3-year follow-up of naturalistic treated depressed inpatients. BMC Psychiatry (2016) 0.75

Mental Health in Allergic Rhinitis: Depression and Suicidal Behavior. Curr Treat Options Allergy (2017) 0.75

Advances in Psychotherapy for Depressed Older Adults. Curr Psychiatry Rep (2017) 0.75

Predictors of Mental Health Services Use Across the Life Course among Racially-Ethnically Diverse Adults. Am J Geriatr Psychiatry (2017) 0.75

Articles cited by this

"Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res (1975) 301.74

A rating scale for depression. J Neurol Neurosurg Psychiatry (1960) 90.89

Collaborative care management of late-life depression in the primary care setting: a randomized controlled trial. JAMA (2002) 15.53

Effects of treating depression and low perceived social support on clinical events after myocardial infarction: the Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) Randomized Trial. JAMA (2003) 10.59

Reducing suicidal ideation and depressive symptoms in depressed older primary care patients: a randomized controlled trial. JAMA (2004) 8.83

Assessment of suicidal intention: the Scale for Suicide Ideation. J Consult Clin Psychol (1979) 8.44

Maintenance treatment of major depression in old age. N Engl J Med (2006) 7.61

Educational and organizational interventions to improve the management of depression in primary care: a systematic review. JAMA (2003) 6.72

Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors. Br J Psychiatry (2001) 4.33

Managing depression as a chronic disease: a randomised trial of ongoing treatment in primary care. BMJ (2002) 4.28

Relationships of age and axis I diagnoses in victims of completed suicide: a psychological autopsy study. Am J Psychiatry (1996) 3.61

Long term outcomes from the IMPACT randomised trial for depressed elderly patients in primary care. BMJ (2006) 3.47

The effect of a primary care practice-based depression intervention on mortality in older adults: a randomized trial. Ann Intern Med (2007) 2.84

Intent-to-treat analysis for longitudinal studies with drop-outs. Biometrics (1996) 2.62

Psychiatric status and 9-year mortality data in the New Haven Epidemiologic Catchment Area Study. Am J Psychiatry (1994) 2.39

Cost-effectiveness of improving primary care treatment of late-life depression. Arch Gen Psychiatry (2005) 2.12

Type I and Type II error under random-effects misspecification in generalized linear mixed models. Biometrics (2007) 2.11

Depression treatment in a sample of 1,801 depressed older adults in primary care. J Am Geriatr Soc (2003) 2.09

Mixed effects logistic regression models for longitudinal binary response data with informative drop-out. Biometrics (1998) 1.73

Psychiatric disorders in older primary care patients. J Gen Intern Med (1999) 1.70

Suicidal behavior in elders. Psychiatr Clin North Am (2008) 1.61

Occurrence and course of suicidality during short-term treatment of late-life depression. Arch Gen Psychiatry (2003) 1.60

Suicidal and death ideation in older primary care patients with depression, anxiety, and at-risk alcohol use. Am J Geriatr Psychiatry (2002) 1.39

Pharmacological treatment of depression in older primary care patients: the PROSPECT algorithm. Int J Geriatr Psychiatry (2001) 1.32

Suicidal ideation and risk levels among primary care patients with uncomplicated depression. Ann Fam Med (2005) 1.11

How do you define remission? Acta Psychiatr Scand Suppl (2002) 1.09

Factors of suicide ideation and their relation to clinical and other indicators in older adults. J Affect Disord (2006) 1.00

High levels of hopelessness persist in geriatric patients with remitted depression and a history of attempted suicide. J Am Geriatr Soc (1998) 0.97

Articles by these authors

Reducing suicidal ideation and depressive symptoms in depressed older primary care patients: a randomized controlled trial. JAMA (2004) 8.83

Maintenance treatment of major depression in old age. N Engl J Med (2006) 7.61

Cognitive therapy for the prevention of suicide attempts: a randomized controlled trial. JAMA (2005) 6.23

Treatment of complicated grief: a randomized controlled trial. JAMA (2005) 5.15

Healthy older adults' sleep predicts all-cause mortality at 4 to 19 years of follow-up. Psychosom Med (2003) 4.30

Telephone-delivered collaborative care for treating post-CABG depression: a randomized controlled trial. JAMA (2009) 4.06

Antidepressant pharmacotherapy in the treatment of depression in the very old: a randomized, placebo-controlled trial. Am J Psychiatry (2004) 3.84

Efficacy of brief behavioral treatment for chronic insomnia in older adults. Arch Intern Med (2011) 3.73

Recruiting and retaining future generations of physician scientists in mental health. Arch Gen Psychiatry (2002) 3.69

Major depression in elderly home health care patients. Am J Psychiatry (2002) 3.37

Improving access to geriatric mental health services: a randomized trial comparing treatment engagement with integrated versus enhanced referral care for depression, anxiety, and at-risk alcohol use. Am J Psychiatry (2004) 3.28

Outcomes of minor and subsyndromal depression among elderly patients in primary care settings. Ann Intern Med (2006) 3.27

Re-engineering systems for the treatment of depression in primary care: cluster randomised controlled trial. BMJ (2004) 3.23

The nature and determinants of neuropsychological functioning in late-life depression. Arch Gen Psychiatry (2004) 3.17

Confronting depression and suicide in physicians: a consensus statement. JAMA (2003) 3.06

The long-term effects of conventional and atypical antipsychotics in patients with probable Alzheimer's disease. Am J Psychiatry (2013) 3.06

Preventing depression: a global priority. JAMA (2012) 2.92

Effect of unrelated comorbid conditions on hypertension management. Ann Intern Med (2008) 2.85

The effect of a primary care practice-based depression intervention on mortality in older adults: a randomized trial. Ann Intern Med (2007) 2.84

Depression and Bipolar Support Alliance consensus statement on the unmet needs in diagnosis and treatment of mood disorders in late life. Arch Gen Psychiatry (2003) 2.70

Escitalopram for older adults with generalized anxiety disorder: a randomized controlled trial. JAMA (2009) 2.60

High occurrence of mood and anxiety disorders among older adults: The National Comorbidity Survey Replication. Arch Gen Psychiatry (2010) 2.43

Epidemiological and clinical relevance of insomnia diagnosis algorithms according to the DSM-IV and the International Classification of Sleep Disorders (ICSD). Sleep Med (2009) 2.40

Older adults' attitudes toward enrollment of non-competent subjects participating in Alzheimer's research. Am J Psychiatry (2008) 2.37

A double-blind, placebo-controlled trial combining sertraline and naltrexone for treating co-occurring depression and alcohol dependence. Am J Psychiatry (2010) 2.34

Pathways linking late-life depression to persistent cognitive impairment and dementia. Dialogues Clin Neurosci (2008) 2.30

Perspectives on depression, mild cognitive impairment, and cognitive decline. Arch Gen Psychiatry (2006) 2.29

Depressive and anxiety disorders in women with HIV infection. Am J Psychiatry (2002) 2.26

Test characteristics of the 15-item geriatric depression scale and Hamilton depression rating scale in Parkinson disease. Am J Geriatr Psychiatry (2006) 2.26

Late-life depression and risk of vascular dementia and Alzheimer's disease: systematic review and meta-analysis of community-based cohort studies. Br J Psychiatry (2013) 2.23

Diabetes, depression, and death: a randomized controlled trial of a depression treatment program for older adults based in primary care (PROSPECT). Diabetes Care (2007) 2.23

Effects of a brief behavioral treatment for late-life insomnia: preliminary findings. J Clin Sleep Med (2006) 2.22

The course of functional decline in older people with persistently elevated depressive symptoms: longitudinal findings from the Cardiovascular Health Study. J Am Geriatr Soc (2005) 2.20

Persistence of cognitive impairment in geriatric patients following antidepressant treatment: a randomized, double-blind clinical trial with nortriptyline and paroxetine. J Psychiatr Res (2003) 2.14

A fully automated method for quantifying and localizing white matter hyperintensities on MR images. Psychiatry Res (2006) 2.08

Depression, antidepressants, and bone health in older adults: a systematic review. J Am Geriatr Soc (2014) 2.08

Effect of concomitant pharmacotherapy on electroconvulsive therapy outcomes: short-term efficacy and adverse effects. Arch Gen Psychiatry (2009) 2.08

Bridging community intervention and mental health services research. Am J Psychiatry (2004) 2.06

A double-blind comparison of citalopram and risperidone for the treatment of behavioral and psychotic symptoms associated with dementia. Am J Geriatr Psychiatry (2007) 2.04

Remission in depressed geriatric primary care patients: a report from the PROSPECT study. Am J Psychiatry (2005) 2.04

The status of naltrexone in the treatment of alcohol dependence: specific effects on heavy drinking. J Clin Psychopharmacol (2006) 2.00

Problem-solving therapy and supportive therapy in older adults with major depression and executive dysfunction: effect on disability. Arch Gen Psychiatry (2011) 2.00

Effect of psychiatric and other nonmotor symptoms on disability in Parkinson's disease. J Am Geriatr Soc (2004) 2.00

Race, stigma, and mental health referrals among clients of aging services who screened positive for depression. Psychiatr Serv (2014) 1.98

Methodological challenges in constructing effective treatment sequences for chronic psychiatric disorders. Neuropsychopharmacology (2006) 1.93

Long term effect of depression care management on mortality in older adults: follow-up of cluster randomized clinical trial in primary care. BMJ (2013) 1.91

Recognition of depression among elderly recipients of home care services. Psychiatr Serv (2003) 1.86

Preventing the onset of major depressive disorder: a meta-analytic review of psychological interventions. Int J Epidemiol (2014) 1.85

Onset of depression in elderly persons after hip fracture: implications for prevention and early intervention of late-life depression. J Am Geriatr Soc (2007) 1.85

Using a Bayesian latent growth curve model to identify trajectories of positive affect and negative events following myocardial infarction. Biostatistics (2005) 1.84

Persistence of neuropsychologic deficits in the remitted state of late-life depression. Am J Geriatr Psychiatry (2006) 1.77

Age-related decline in white matter tract integrity and cognitive performance: a DTI tractography and structural equation modeling study. Neurobiol Aging (2010) 1.77

Post stroke depression: epidemiology, pathophysiology, and biological treatment. Biol Psychiatry (2002) 1.76

Efficacy and tolerability of citalopram in the treatment of late-life anxiety disorders: results from an 8-week randomized, placebo-controlled trial. Am J Psychiatry (2005) 1.76

The relationship between pain and mental flexibility in older adult pain clinic patients. Pain Med (2006) 1.75

Provisional diagnostic criteria for depression of Alzheimer disease. Am J Geriatr Psychiatry (2002) 1.75

Clinical presentation of the "depression-executive dysfunction syndrome" of late life. Am J Geriatr Psychiatry (2002) 1.73

Cardiovascular changes associated with venlafaxine in the treatment of late-life depression. Am J Geriatr Psychiatry (2006) 1.73

Recognition and treatment of depression in Parkinson's disease. J Geriatr Psychiatry Neurol (2003) 1.71

Brain morphometric abnormalities in geriatric depression: long-term neurobiological effects of illness duration. Am J Psychiatry (2002) 1.70

Patients' depression treatment preferences and initiation, adherence, and outcome: a randomized primary care study. Psychiatr Serv (2009) 1.70

Physical and mental health of homebound older adults: an overlooked population. J Am Geriatr Soc (2010) 1.69

Effect of rehabilitation site on functional recovery after hip fracture. Arch Phys Med Rehabil (2005) 1.69

Extended telephone-based continuing care for alcohol dependence: 24-month outcomes and subgroup analyses. Addiction (2011) 1.68

Recovery from major depression in older adults receiving augmentation of antidepressant pharmacotherapy. Am J Psychiatry (2007) 1.68

Mental health treatment seeking among older adults with depression: the impact of stigma and race. Am J Geriatr Psychiatry (2010) 1.67

Cancer and the media: how does the news report on treatment and outcomes? Arch Intern Med (2010) 1.67

Cognitive impairment in late-life generalized anxiety disorder. Am J Geriatr Psychiatry (2007) 1.67

A randomized trial to improve the quality of treatment for panic and generalized anxiety disorders in primary care. Arch Gen Psychiatry (2005) 1.65

Can performance on daily activities discriminate between older adults with normal cognitive function and those with mild cognitive impairment? J Am Geriatr Soc (2014) 1.65

Depressive symptoms and suicidal ideation among older adults receiving home delivered meals. Int J Geriatr Psychiatry (2008) 1.63

Pharmacological strategies in the prevention of relapse after electroconvulsive therapy. J ECT (2013) 1.62

Operational definitions and algorithms for excessive sleepiness in the general population: implications for DSM-5 nosology. Arch Gen Psychiatry (2012) 1.62