Published in Psychiatry Res on November 13, 2006
Cognitive profile of amyloid burden and white matter hyperintensities in cognitively normal older adults. J Neurosci (2012) 1.76
Arterial stiffness and β-amyloid progression in nondemented elderly adults. JAMA Neurol (2014) 1.63
Fully-automated white matter hyperintensity detection with anatomical prior knowledge and without FLAIR. Inf Process Med Imaging (2009) 1.51
Cerebral circulation time is prolonged and not correlated with EDSS in multiple sclerosis patients: a study using digital subtracted angiography. PLoS One (2015) 1.39
Brain Activation and Psychomotor Speed in Middle-Aged Patients with Type 1 Diabetes: Relationships with Hyperglycemia and Brain Small Vessel Disease. J Diabetes Res (2016) 1.39
Gray matter changes in late life depression--a structural MRI analysis. Neuropsychopharmacology (2007) 1.35
White matter lesions and brain gray matter volume in cognitively normal elders. Neurobiol Aging (2011) 1.26
Default-mode network connectivity and white matter burden in late-life depression. Psychiatry Res (2011) 1.23
Quantitative approaches for assessment of white matter hyperintensities in elderly populations. Psychiatry Res (2011) 1.22
Pulse wave velocity is associated with β-amyloid deposition in the brains of very elderly adults. Neurology (2013) 1.18
Macro- and microstructural magnetic resonance imaging indices associated with diabetes among community-dwelling older adults. Diabetes Care (2012) 1.14
fMRI correlates of white matter hyperintensities in late-life depression. Am J Psychiatry (2011) 1.13
Failure to modulate attentional control in advanced aging linked to white matter pathology. Cereb Cortex (2011) 1.12
Automatic segmentation of white matter hyperintensities in the elderly using FLAIR images at 3T. J Magn Reson Imaging (2010) 1.07
Lower Digit Symbol Substitution Score in the Oldest Old is Related to Magnetization Transfer and Diffusion Tensor Imaging of the White Matter. Front Aging Neurosci (2011) 1.04
Multiple Brain Markers are Linked to Age-Related Variation in Cognition. Cereb Cortex (2014) 1.02
Cerebral control of the lower urinary tract: how age-related changes might predispose to urge incontinence. Neuroimage (2009) 1.02
Brain activity during bladder filling is related to white matter structural changes in older women with urinary incontinence. Neuroimage (2010) 1.01
Neuroimaging differences between older adults with maintained versus declining cognition over a 10-year period. Neuroimage (2012) 0.99
Maintaining brain health by monitoring inflammatory processes: a mechanism to promote successful aging. Aging Dis (2011) 0.97
MRI signal hyperintensities and treatment remission of geriatric depression. J Affect Disord (2010) 0.95
Use of total cerebral blood flow as an imaging biomarker of known cardiovascular risks. Stroke (2013) 0.95
Physical activity predicts microstructural integrity in memory-related networks in very old adults. J Gerontol A Biol Sci Med Sci (2014) 0.94
fMRI activation in late-life anxious depression: a potential biomarker. Int J Geriatr Psychiatry (2009) 0.94
Pathways linking regional hyperintensities in the brain and slower gait. Neuroimage (2014) 0.94
Regional grey matter shrinks in hypertensive individuals despite successful lowering of blood pressure. J Hum Hypertens (2011) 0.93
Increased white matter signal hyperintensities in long-term abstinent alcoholics compared with nonalcoholic controls. Alcohol Clin Exp Res (2008) 0.92
Patterns of focal gray matter atrophy are associated with bradykinesia and gait disturbances in older adults. J Gerontol A Biol Sci Med Sci (2012) 0.92
Plasma biosignature and brain pathology related to persistent cognitive impairment in late-life depression. Mol Psychiatry (2014) 0.89
White matter hyperintensities, exercise, and improvement in gait speed: does type of gait rehabilitation matter? J Am Geriatr Soc (2013) 0.89
Automatic Detection of White Matter Hyperintensities in Healthy Aging and Pathology Using Magnetic Resonance Imaging: A Review. Neuroinformatics (2015) 0.88
Cerebral White Matter and Slow Gait: Contribution of Hyperintensities and Normal-appearing Parenchyma. J Gerontol A Biol Sci Med Sci (2016) 0.85
Automated detection of white matter signal abnormality using T2 relaxometry: application to brain segmentation on term MRI in very preterm infants. Neuroimage (2012) 0.84
White matter hyperintensities segmentation: a new semi-automated method. Front Aging Neurosci (2013) 0.84
The haptoglobin 1 allele correlates with white matter hyperintensities in middle-aged adults with type 1 diabetes. Diabetes (2014) 0.83
Association of small vessel ischemic white matter changes with BOLD fMRI imaging in the elderly. Psychiatry Res (2012) 0.83
Machine learning approaches for integrating clinical and imaging features in late-life depression classification and response prediction. Int J Geriatr Psychiatry (2015) 0.83
Cardiorespiratory fitness and brain diffusion tensor imaging in adults over 80 years of age. Brain Res (2014) 0.82
White matter hyperintensity burden and disability in older adults: is chronic pain a contributor? PM R (2013) 0.81
Longer lithium exposure is associated with better white matter integrity in older adults with bipolar disorder. Bipolar Disord (2014) 0.81
Multimodal MRI markers support a model of small vessel ischemia for depressive symptoms in very old adults. Psychiatry Res (2014) 0.81
Longitudinal systolic blood pressure characteristics and integrity of white matter tracts in a cohort of very old black and white adults. Am J Hypertens (2014) 0.81
White Matter Hyperintensity Accumulation During Treatment of Late-Life Depression. Neuropsychopharmacology (2015) 0.80
Subjective Cognitive Complaints, Personality and Brain Amyloid-beta in Cognitively Normal Older Adults. Am J Geriatr Psychiatry (2015) 0.80
Accelerated decline in white matter integrity in clinically normal individuals at risk for Alzheimer's disease. Neurobiol Aging (2016) 0.80
Neuroimaging and neurocognitive abnormalities associated with bipolar disorder in old age. Int J Geriatr Psychiatry (2013) 0.80
Menopausal hot flashes and white matter hyperintensities. Menopause (2016) 0.80
Declines in inflammation predict greater white matter microstructure in older adults. Neurobiol Aging (2014) 0.80
The relationship between interleukin-1 receptor antagonist and cognitive function in older adults with bipolar disorder. Int J Geriatr Psychiatry (2013) 0.80
Age of Childhood Onset in Type 1 Diabetes and Functional Brain Connectivity in Midlife. Psychosom Med (2015) 0.80
Validation of automated white matter hyperintensity segmentation. J Aging Res (2011) 0.79
Amyloid, neurodegeneration, and small vessel disease as predictors of dementia in the oldest-old. Neurology (2014) 0.79
Corticostriatothalamic reward prediction error signals and executive control in late-life depression. Psychol Med (2014) 0.78
Objective measures of physical activity, white matter integrity and cognitive status in adults over age 80. Behav Brain Res (2015) 0.78
Application of variable threshold intensity to segmentation for white matter hyperintensities in fluid attenuated inversion recovery magnetic resonance images. Neuroradiology (2014) 0.78
Delays in auditory-cued step initiation are related to increased volume of white matter hyperintensities in older adults. Exp Brain Res (2008) 0.78
Automated identification of brain tumors from single MR images based on segmentation with refined patient-specific priors. Front Neurosci (2013) 0.77
Statins and brain integrity in older adults: Secondary analysis of the Health ABC study. Alzheimers Dement (2015) 0.77
Contrast-based fully automatic segmentation of white matter hyperintensities: method and validation. PLoS One (2012) 0.77
Intrinsic functional connectivity in late-life depression: trajectories over the course of pharmacotherapy in remitters and non-remitters. Mol Psychiatry (2016) 0.76
Bidirectional iterative parcellation of diffusion weighted imaging data: separating cortical regions connected by the arcuate fasciculus and extreme capsule. Neuroimage (2014) 0.76
Dopamine transporter availability in clinically normal aging is associated with individual differences in white matter integrity. Hum Brain Mapp (2015) 0.75
Altered Synchronizations among Neural Networks in Geriatric Depression. Biomed Res Int (2015) 0.75
Slow gait, white matter characteristics, and prior 10-year interleukin-6 levels in older adults. Neurology (2016) 0.75
Enhanced Molecular Aging in Late-Life Depression: the Senescent-Associated Secretory Phenotype. Am J Geriatr Psychiatry (2016) 0.75
Reduced binding of Pittsburgh Compound-B in areas of white matter hyperintensities. Neuroimage Clin (2015) 0.75
Physical activity and hippocampal volume in middle-aged patients with type 1 diabetes. Neurology (2017) 0.75
Racial Differences in Gray Matter Integrity by Diffusion Tensor in Black and White Octogenarians. Curr Alzheimer Res (2015) 0.75
Metabolic Aberrations Impact Biophysical Integrity of Macromolecular Protein Pools in the Default Mode Network. Diabetes (2016) 0.75
Long-term changes in time spent walking and subsequent cognitive and structural brain changes in older adults. Neurobiol Aging (2017) 0.75
Cognitive Status, Gray Matter Atrophy, and Lower Orthostatic Blood Pressure in Older Adults. J Alzheimers Dis (2017) 0.75
Brain structural changes in late-life generalized anxiety disorder. Psychiatry Res (2017) 0.75
Fast robust automated brain extraction. Hum Brain Mapp (2002) 41.79
Fiber tract-based atlas of human white matter anatomy. Radiology (2003) 10.18
MR signal abnormalities at 1.5 T in Alzheimer's dementia and normal aging. AJR Am J Roentgenol (1987) 8.48
Anatomical mapping of white matter hyperintensities (WMH): exploring the relationships between periventricular WMH, deep WMH, and total WMH burden. Stroke (2004) 3.80
A method for using MR to evaluate the effects of cardiovascular disease on the brain: the cardiovascular health study. AJNR Am J Neuroradiol (1994) 3.07
Probabilistic segmentation of white matter lesions in MR imaging. Neuroimage (2004) 2.66
White matter lesion progression, brain atrophy, and cognitive decline: the Austrian stroke prevention study. Ann Neurol (2005) 2.29
Anxiety and depression in later life: Co-occurrence and communality of risk factors. Am J Psychiatry (2000) 2.28
FLAIR histogram segmentation for measurement of leukoaraiosis volume. J Magn Reson Imaging (2001) 2.24
Sulcal, ventricular, and white matter changes at MR imaging in the aging brain: data from the cardiovascular health study. Radiology (1997) 2.13
Routine quantitative analysis of brain and cerebrospinal fluid spaces with MR imaging. J Magn Reson Imaging (1992) 2.11
The topography of white matter hyperintensities on brain MRI in healthy 60- to 64-year-old individuals. Neuroimage (2004) 2.04
Older people with impaired mobility have specific loci of periventricular abnormality on MRI. Neurology (2002) 2.00
Multiple sclerosis lesion quantification using fuzzy-connectedness principles. IEEE Trans Med Imaging (1997) 1.82
Depression and vascular disease: what is the relationship? J Affect Disord (2004) 1.43
Morphometric analysis of gray matter volume in demented older adults: exploratory analysis of the cardiovascular health study brain MRI database. Neuroepidemiology (2005) 1.32
Automatic segmentation of different-sized white matter lesions by voxel probability estimation. Med Image Anal (2004) 1.25
Impact of white matter changes on clinical manifestation of Alzheimer's disease: A quantitative study. Stroke (2000) 1.24
Prefrontal and striatal activation during sequence learning in geriatric depression. Biol Psychiatry (2005) 1.20
White matter hyperintensities are significantly associated with cortical atrophy in Alzheimer's disease. J Neurol Neurosurg Psychiatry (2004) 1.16
The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part III. Reliability of a standardized MRI evaluation of Alzheimer's disease. Neurology (1992) 1.16
Clinical correlates of white-matter changes on magnetic resonance imaging scans of the brain. Arch Neurol (1991) 1.12
Localization of age-associated white matter hyperintensities in late-life depression. Prog Neuropsychopharmacol Biol Psychiatry (2003) 1.11
Identifying lesions on structural brain images--validation of the method and application to neuropsychological patients. Brain Lang (2005) 1.11
Leukoaraiosis and vascular dementia. Neurology (1998) 0.94
Utility of simultaneous brain, CSF and hyperintensity quantification in dementia. Psychiatry Res (2002) 0.92
Late-onset depressive disorders: a preventable variant of cerebrovascular disease? Psychol Med (1998) 0.92
Computer-assisted quantitation of enhancing lesions in multiple sclerosis: correlation with clinical classification. AJNR Am J Neuroradiol (1997) 0.88
A pyramidal approach for automatic segmentation of multiple sclerosis lesions in brain MRI. Comput Med Imaging Graph (1999) 0.82
Gait speed and survival in older adults. JAMA (2011) 15.01
Reducing suicidal ideation and depressive symptoms in depressed older primary care patients: a randomized controlled trial. JAMA (2004) 8.83
Kinetic modeling of amyloid binding in humans using PET imaging and Pittsburgh Compound-B. J Cereb Blood Flow Metab (2005) 6.25
Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease. Proc Natl Acad Sci U S A (2009) 5.55
Treatment of complicated grief: a randomized controlled trial. JAMA (2005) 5.15
Simplified quantification of Pittsburgh Compound B amyloid imaging PET studies: a comparative analysis. J Nucl Med (2005) 5.10
Healthy older adults' sleep predicts all-cause mortality at 4 to 19 years of follow-up. Psychosom Med (2003) 4.30
Telephone-delivered collaborative care for treating post-CABG depression: a randomized controlled trial. JAMA (2009) 4.06
Amyloid deposition begins in the striatum of presenilin-1 mutation carriers from two unrelated pedigrees. J Neurosci (2007) 3.91
Efficacy of brief behavioral treatment for chronic insomnia in older adults. Arch Intern Med (2011) 3.73
Recruiting and retaining future generations of physician scientists in mental health. Arch Gen Psychiatry (2002) 3.69
Cognitive function, gait speed decline, and comorbidities: the health, aging and body composition study. J Gerontol A Biol Sci Med Sci (2007) 3.61
Limited literacy and mortality in the elderly: the health, aging, and body composition study. J Gen Intern Med (2006) 3.51
Outcomes of minor and subsyndromal depression among elderly patients in primary care settings. Ann Intern Med (2006) 3.27
The nature and determinants of neuropsychological functioning in late-life depression. Arch Gen Psychiatry (2004) 3.17
Confronting depression and suicide in physicians: a consensus statement. JAMA (2003) 3.06
The long-term effects of conventional and atypical antipsychotics in patients with probable Alzheimer's disease. Am J Psychiatry (2013) 3.06
Preventing depression: a global priority. JAMA (2012) 2.92
Neurotransplantation for patients with subcortical motor stroke: a phase 2 randomized trial. J Neurosurg (2005) 2.87
Thinning of the cerebral cortex visualized in HIV/AIDS reflects CD4+ T lymphocyte decline. Proc Natl Acad Sci U S A (2005) 2.79
Depression and Bipolar Support Alliance consensus statement on the unmet needs in diagnosis and treatment of mood disorders in late life. Arch Gen Psychiatry (2003) 2.70
3D pattern of brain atrophy in HIV/AIDS visualized using tensor-based morphometry. Neuroimage (2006) 2.69
Amyloid imaging in mild cognitive impairment subtypes. Ann Neurol (2009) 2.66
Escitalopram for older adults with generalized anxiety disorder: a randomized controlled trial. JAMA (2009) 2.60
Reducing suicidal ideation and depression in older primary care patients: 24-month outcomes of the PROSPECT study. Am J Psychiatry (2009) 2.56
Epidemiological and clinical relevance of insomnia diagnosis algorithms according to the DSM-IV and the International Classification of Sleep Disorders (ICSD). Sleep Med (2009) 2.40
Pathways linking late-life depression to persistent cognitive impairment and dementia. Dialogues Clin Neurosci (2008) 2.30
Perspectives on depression, mild cognitive impairment, and cognitive decline. Arch Gen Psychiatry (2006) 2.29
Late-life depression and risk of vascular dementia and Alzheimer's disease: systematic review and meta-analysis of community-based cohort studies. Br J Psychiatry (2013) 2.23
Effects of a brief behavioral treatment for late-life insomnia: preliminary findings. J Clin Sleep Med (2006) 2.22
The course of functional decline in older people with persistently elevated depressive symptoms: longitudinal findings from the Cardiovascular Health Study. J Am Geriatr Soc (2005) 2.20
Multitasking: association between poorer performance and a history of recurrent falls. J Am Geriatr Soc (2007) 2.17
Persistence of cognitive impairment in geriatric patients following antidepressant treatment: a randomized, double-blind clinical trial with nortriptyline and paroxetine. J Psychiatr Res (2003) 2.14
Depression, antidepressants, and bone health in older adults: a systematic review. J Am Geriatr Soc (2014) 2.08
Limited literacy in older people and disparities in health and healthcare access. J Am Geriatr Soc (2006) 2.06
Remission in depressed geriatric primary care patients: a report from the PROSPECT study. Am J Psychiatry (2005) 2.04
Relationship between vitamin B12 and sensory and motor peripheral nerve function in older adults. J Am Geriatr Soc (2012) 1.96
3D mapping of ventricular and corpus callosum abnormalities in HIV/AIDS. Neuroimage (2006) 1.93
Long term effect of depression care management on mortality in older adults: follow-up of cluster randomized clinical trial in primary care. BMJ (2013) 1.91
PET/CT: form and function. Radiology (2007) 1.89
Diabetes, glucose control, and 9-year cognitive decline among older adults without dementia. Arch Neurol (2012) 1.87
Preventing the onset of major depressive disorder: a meta-analytic review of psychological interventions. Int J Epidemiol (2014) 1.85
Onset of depression in elderly persons after hip fracture: implications for prevention and early intervention of late-life depression. J Am Geriatr Soc (2007) 1.85
Prevalence of cognitive disorders differs as a function of age in HIV virus infection. AIDS (2004) 1.84
A regions-of-interest volumetric analysis of mobility limitations in community-dwelling older adults. J Gerontol A Biol Sci Med Sci (2007) 1.83
Serotonin 1A receptor reductions in postpartum depression: a positron emission tomography study. Fertil Steril (2007) 1.82
Increased dopamine D2/D3 receptor binding after recovery from anorexia nervosa measured by positron emission tomography and [11c]raclopride. Biol Psychiatry (2005) 1.80
Tracking Alzheimer's disease. Ann N Y Acad Sci (2007) 1.78
Persistence of neuropsychologic deficits in the remitted state of late-life depression. Am J Geriatr Psychiatry (2006) 1.77
Efficacy and tolerability of citalopram in the treatment of late-life anxiety disorders: results from an 8-week randomized, placebo-controlled trial. Am J Psychiatry (2005) 1.76
The relationship between pain and mental flexibility in older adult pain clinic patients. Pain Med (2006) 1.75
Provisional diagnostic criteria for depression of Alzheimer disease. Am J Geriatr Psychiatry (2002) 1.75
Cardiovascular changes associated with venlafaxine in the treatment of late-life depression. Am J Geriatr Psychiatry (2006) 1.73
Brain morphometric abnormalities in geriatric depression: long-term neurobiological effects of illness duration. Am J Psychiatry (2002) 1.70
Effect of rehabilitation site on functional recovery after hip fracture. Arch Phys Med Rehabil (2005) 1.69
Recovery from major depression in older adults receiving augmentation of antidepressant pharmacotherapy. Am J Psychiatry (2007) 1.68
Gait speed predicts decline in attention and psychomotor speed in older adults: the health aging and body composition study. Neuroepidemiology (2007) 1.68
Mental health treatment seeking among older adults with depression: the impact of stigma and race. Am J Geriatr Psychiatry (2010) 1.67
Cognitive impairment in late-life generalized anxiety disorder. Am J Geriatr Psychiatry (2007) 1.67
A randomized trial to improve the quality of treatment for panic and generalized anxiety disorders in primary care. Arch Gen Psychiatry (2005) 1.65
Can performance on daily activities discriminate between older adults with normal cognitive function and those with mild cognitive impairment? J Am Geriatr Soc (2014) 1.65
Operational definitions and algorithms for excessive sleepiness in the general population: implications for DSM-5 nosology. Arch Gen Psychiatry (2012) 1.62
Occurrence and course of suicidality during short-term treatment of late-life depression. Arch Gen Psychiatry (2003) 1.60
Effect of comorbid anxiety on treatment response and relapse risk in late-life depression: controlled study. Br J Psychiatry (2007) 1.60
Gain in adiposity across 15 years is associated with reduced gray matter volume in healthy women. Psychosom Med (2009) 1.60
Head and neck malignancy: is PET/CT more accurate than PET or CT alone? Radiology (2005) 1.59
The prevalence and correlates of psychiatric comorbidity in individuals with complicated grief. Compr Psychiatry (2007) 1.59
Serum leptin level and cognition in the elderly: Findings from the Health ABC Study. Neurobiol Aging (2008) 1.59
Optimum template selection for atlas-based segmentation. Neuroimage (2006) 1.58
Quantitative comparison of AIR, SPM, and the fully deformable model for atlas-based segmentation of functional and structural MR images. Hum Brain Mapp (2006) 1.57
Serotonin transporter binding after recovery from eating disorders. Psychopharmacology (Berl) (2007) 1.57
Depressed mood is not a risk factor for incident dementia in a community-based cohort. Am J Geriatr Psychiatry (2009) 1.54
Programs for developing the pipeline of early-career geriatric mental health researchers: outcomes and implications for other fields. Acad Med (2010) 1.52
Brain imaging findings predict blood pressure response to pharmacological treatment. Hypertension (2008) 1.52
Mean template for tensor-based morphometry using deformation tensors. Med Image Comput Comput Assist Interv (2007) 1.52
Adverse effects of depression and cognitive impairment on rehabilitation participation and recovery from hip fracture. Int J Geriatr Psychiatry (2004) 1.51
The efficacy of psychotherapy and pharmacotherapy in treating depressive and anxiety disorders: a meta-analysis of direct comparisons. World Psychiatry (2013) 1.51
Human regional cerebral glucose metabolism during non-rapid eye movement sleep in relation to waking. Brain (2002) 1.50
Maintenance treatment for old-age depression preserves health-related quality of life: a randomized, controlled trial of paroxetine and interpersonal psychotherapy. J Am Geriatr Soc (2007) 1.50
Bereavement, complicated grief, and DSM, part 1: depression. J Clin Psychiatry (2010) 1.49
Pain predicts longer time to remission during treatment of recurrent depression. J Clin Psychiatry (2005) 1.49
A developmental model for enhancing research training during psychiatry residency. Acad Psychiatry (2006) 1.48
Empirically derived decision trees for the treatment of late-life depression. Am J Psychiatry (2008) 1.48
Patterns of mild cognitive impairment after treatment of depression in the elderly. Am J Geriatr Psychiatry (2009) 1.48
The relationship of medical comorbidity and depression in older, primary care patients. Psychosomatics (2006) 1.47
Altered functioning of the executive control circuit in late-life depression: episodic and persistent phenomena. Am J Geriatr Psychiatry (2009) 1.47
How does depression influence diabetes medication adherence in older patients? Am J Geriatr Psychiatry (2005) 1.46
Socioeconomic differences in cognitive decline and the role of biomedical factors. Ann Epidemiol (2005) 1.45
Issues, controversies, and clinical utility of combined PET/CT imaging: what is the interpreting physician facing? AJR Am J Roentgenol (2005) 1.44
The Pittsburgh Rehabilitation Participation Scale: reliability and validity of a clinician-rated measure of participation in acute rehabilitation. Arch Phys Med Rehabil (2004) 1.44
The effect of the US Medicare Part D coverage gaps on medication use among patients with depression and heart failure. J Ment Health Policy Econ (2012) 1.42
Slower gait, slower information processing and smaller prefrontal area in older adults. Age Ageing (2011) 1.42
Financial strain is a significant correlate of sleep continuity disturbances in late-life. Biol Psychol (2007) 1.41
Effect of nortriptyline and paroxetine on CYP2D6 activity in depressed elderly patients. J Clin Psychopharmacol (2002) 1.41