Published in Genes Dev on June 15, 2009
The molecular genetics of holoprosencephaly. Am J Med Genet C Semin Med Genet (2010) 1.57
B1 SOX coordinate cell specification with patterning and morphogenesis in the early zebrafish embryo. PLoS Genet (2010) 1.15
ZIC1 modulates cell-cycle distributions and cell migration through regulation of sonic hedgehog, PI(3)K and MAPK signaling pathways in gastric cancer. BMC Cancer (2012) 1.00
Advances in the targeted therapy of liposarcoma. Onco Targets Ther (2015) 0.99
Genesis of teratogen-induced holoprosencephaly in mice. Am J Med Genet C Semin Med Genet (2010) 0.97
The germinal zones of the basal ganglia but not the septum generate GABAergic interneurons for the cortex. J Neurosci (2010) 0.95
Expression of the zic1, zic2, zic3, and zic4 genes in early chick embryos. BMC Res Notes (2010) 0.92
ZIC1 is downregulated through promoter hypermethylation, and functions as a tumor suppressor gene in colorectal cancer. PLoS One (2011) 0.91
Expression pattern and functions of autophagy-related gene atg5 in zebrafish organogenesis. Autophagy (2011) 0.90
Zebrafish zic2a patterns the forebrain through modulation of Hedgehog-activated gene expression. Development (2009) 0.89
zic-1 Expression in Planarian neoblasts after injury controls anterior pole regeneration. PLoS Genet (2014) 0.84
Virulence of infecting Helicobacter pylori strains and intensity of mononuclear cell infiltration are associated with levels of DNA hypermethylation in gastric mucosae. Epigenetics (2013) 0.81
Spatiotemporal expression of Zic genes during vertebrate inner ear development. Dev Dyn (2013) 0.80
The role of Zic transcription factors in regulating hindbrain retinoic acid signaling. BMC Dev Biol (2013) 0.78
Zic1 controls placode progenitor formation non-cell autonomously by regulating retinoic acid production and transport. Nat Commun (2015) 0.78
Zebrafish Zic2a and Zic2b regulate neural crest and craniofacial development. Dev Biol (2013) 0.76
Initiation of cyp26a1 Expression in the Zebrafish Anterior Neural Plate by a Novel Cis-Acting Element. PLoS One (2016) 0.75
Phosphatidylinositol glycan anchor biosynthesis, class X containing complex promotes cancer cell proliferation through suppression of EHD2 and ZIC1, putative tumor suppressors. Int J Oncol (2016) 0.75
Zebrafish zic2 controls formation of periocular neural crest and choroid fissure morphogenesis. Dev Biol (2017) 0.75
Stages of embryonic development of the zebrafish. Dev Dyn (1995) 42.72
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature (1996) 11.46
A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos. Cell (1993) 3.90
The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures. Genes Dev (2001) 2.74
Patterning activities of vertebrate hedgehog proteins in the developing eye and brain. Curr Biol (1995) 2.54
Holoprosencephaly due to mutations in ZIC2, a homologue of Drosophila odd-paired. Nat Genet (1998) 2.26
The zebrafish slow-muscle-omitted gene product is required for Hedgehog signal transduction and the development of slow muscle identity. Development (2000) 2.25
Spatial regulation of a zebrafish patched homologue reflects the roles of sonic hedgehog and protein kinase A in neural tube and somite patterning. Development (1996) 2.18
Holoprosencephaly: clinical, anatomic, and molecular dimensions. Birth Defects Res A Clin Mol Teratol (2006) 2.11
Induction of the zebrafish ventral brain and floorplate requires cyclops/nodal signalling. Nature (1998) 2.10
Genetic dissection of nodal function in patterning the mouse embryo. Development (2001) 2.07
Midline signalling is required for Pax gene regulation and patterning of the eyes. Development (1995) 1.95
Expression of the zebrafish paired box gene pax[zf-b] during early neurogenesis. Development (1991) 1.81
Cyp26 enzymes generate the retinoic acid response pattern necessary for hindbrain development. Development (2007) 1.79
Left-right asymmetric expression of lefty2 and nodal is induced by a signaling pathway that includes the transcription factor FAST2. Mol Cell (2000) 1.78
cyclops encodes a nodal-related factor involved in midline signaling. Proc Natl Acad Sci U S A (1998) 1.75
The one-eyed pinhead gene functions in mesoderm and endoderm formation in zebrafish and interacts with no tail. Development (1997) 1.73
Holoprosencephaly in human embryos: epidemiologic studies of 150 cases. Teratology (1977) 1.70
Complex regulation of cyp26a1 creates a robust retinoic acid gradient in the zebrafish embryo. PLoS Biol (2007) 1.68
Local retinoid signaling coordinates forebrain and facial morphogenesis by maintaining FGF8 and SHH. Development (2001) 1.63
Retinoic acid-mediated gene expression in transgenic reporter zebrafish. Dev Biol (2001) 1.60
Zebrafish nodal-related genes are implicated in axial patterning and establishing left-right asymmetry. Dev Biol (1998) 1.56
Distinct roles for Fgf, Wnt and retinoic acid in posteriorizing the neural ectoderm. Development (2002) 1.54
Ace/Fgf8 is required for forebrain commissure formation and patterning of the telencephalon. Development (2000) 1.50
Mechanisms of ventral patterning in the vertebrate nervous system. Nat Rev Neurosci (2006) 1.49
Hedgehog signalling maintains the optic stalk-retinal interface through the regulation of Vax gene activity. Development (2003) 1.43
Zic2 controls cerebellar development in cooperation with Zic1. J Neurosci (2002) 1.42
Holoprosencephaly due to mutations in ZIC2: alanine tract expansion mutations may be caused by parental somatic recombination. Hum Mol Genet (2001) 1.38
Vax genes ventralize the embryonic eye. Genes Dev (2005) 1.35
FGF3 and FGF8 mediate a rhombomere 4 signaling activity in the zebrafish hindbrain. Development (2002) 1.34
Zic2 regulates the kinetics of neurulation. Proc Natl Acad Sci U S A (2000) 1.34
Retinoic acid-metabolizing enzyme Cyp26a1 is essential for determining territories of hindbrain and spinal cord in zebrafish. Dev Biol (2005) 1.32
Gli/Zic factors pattern the neural plate by defining domains of cell differentiation. Nature (1998) 1.30
Zebrafish pax[zf-a]: a paired box-containing gene expressed in the neural tube. EMBO J (1991) 1.30
Suppression of apoptosis by bcl-2 overexpression in lymphoid cells of transgenic zebrafish. Blood (2004) 1.26
Retinoic acid establishes ventral retinal characteristics. Development (1996) 1.24
Zic1 and Zic3 regulate medial forebrain development through expansion of neuronal progenitors. J Neurosci (2007) 1.19
Dorsoventral patterning of the Xenopus eye: a collaboration of Retinoid, Hedgehog and FGF receptor signaling. Development (2005) 1.19
Characterisation of a second patched gene in the zebrafish Danio rerio and the differential response of patched genes to Hedgehog signalling. Dev Biol (1999) 1.17
Mutations in the BMP pathway in mice support the existence of two molecular classes of holoprosencephaly. Development (2007) 1.16
Retinoic acid-induced duplication of the zebrafish retina. Proc Natl Acad Sci U S A (1992) 1.16
An essential role for retinoid signaling in anteroposterior neural patterning. Development (1997) 1.15
Zic1 promotes the expansion of dorsal neural progenitors in spinal cord by inhibiting neuronal differentiation. Dev Biol (2002) 1.14
Zic2-associated holoprosencephaly is caused by a transient defect in the organizer region during gastrulation. Hum Mol Genet (2008) 1.12
Unique and combinatorial functions of Fgf3 and Fgf8 during zebrafish forebrain development. Development (2003) 1.11
Developmental regulation of Tbx5 in zebrafish embryogenesis. Mech Dev (2000) 1.10
The nodal pathway acts upstream of hedgehog signaling to specify ventral telencephalic identity. Neuron (2001) 1.10
Direct action of the nodal-related signal cyclops in induction of sonic hedgehog in the ventral midline of the CNS. Development (2000) 1.10
Retinoic acid activates myogenesis in vivo through Fgf8 signalling. Dev Biol (2005) 1.05
Sonic hedgehog signaling in forebrain development and its interactions with pathways that modify its effects. Trends Cell Biol (2006) 1.04
The ups and downs of holoprosencephaly: dorsal versus ventral patterning forces. Clin Genet (2008) 1.03
Anterior movement of ventral diencephalic precursors separates the primordial eye field in the neural plate and requires cyclops. Development (1999) 1.03
Distinct and cooperative roles for Nodal and Hedgehog signals during hypothalamic development. Development (2002) 1.01
Nodal and Fgf pathways interact through a positive regulatory loop and synergize to maintain mesodermal cell populations. Development (2004) 1.00
Zebrafish Radar: a new member of the TGF-beta superfamily defines dorsal regions of the neural plate and the embryonic retina. Mech Dev (1995) 0.98
Zic1 and Zic4 regulate zebrafish roof plate specification and hindbrain ventricle morphogenesis. Dev Biol (2007) 0.98
Zic2 and Zic3 synergistically control neurulation and segmentation of paraxial mesoderm in mouse embryo. Dev Biol (2007) 0.97
zic Gene expression marks anteroposterior pattern in the presumptive neurectoderm of the zebrafish gastrula. Dev Dyn (2001) 0.97
Determination of the zebrafish forebrain: induction and patterning. Development (1998) 0.95
Maternal Xenopus Zic2 negatively regulates Nodal-related gene expression during anteroposterior patterning. Development (2005) 0.90
Zebrafish model of holoprosencephaly demonstrates a key role for TGIF in regulating retinoic acid metabolism. Hum Mol Genet (2007) 0.89
Hedgehog signalling controls zebrafish neural keel morphogenesis via its level-dependent effects on neurogenesis. Dev Dyn (2006) 0.85
Functional association of retinoic acid and hedgehog signaling in Xenopus primary neurogenesis. Development (1999) 0.85
Activation of apoptosis and caspase-3 in zebrafish early gastrulae. Dev Dyn (2004) 0.85
Zebrafish zic1 expression in brain and somites is affected by BMP and hedgehog signalling. Mech Dev (1999) 0.83
Retinoic acid is required for specification of the ventral eye field and for Rathke's pouch in the avian embryo. Int J Dev Biol (2007) 0.82
A novel role for zebrafish zic2a during forebrain development. Dev Biol (2008) 0.82
Youth risk behavior surveillance - United States, 2011. MMWR Surveill Summ (2012) 11.57
Youth risk behavior surveillance - United States, 2009. MMWR Surveill Summ (2010) 9.63
Youth risk behavior surveillance--United States, 2007. MMWR Surveill Summ (2008) 9.04
Youth risk behavior surveillance--United States, 2005. MMWR Surveill Summ (2006) 7.13
Youth risk behavior surveillance--United States, 2013. MMWR Surveill Summ (2014) 6.17
Youth risk behavior surveillance--United States, 2003. MMWR Surveill Summ (2004) 6.12
Specification of the vertebrate eye by a network of eye field transcription factors. Development (2003) 2.86
Sexual identity, sex of sexual contacts, and health-risk behaviors among students in grades 9-12--youth risk behavior surveillance, selected sites, United States, 2001-2009. MMWR Surveill Summ (2011) 2.73
Inhibition of Activin/Nodal signaling promotes specification of human embryonic stem cells into neuroectoderm. Dev Biol (2007) 2.46
Youth risk behavior surveillance--United States, 2005. J Sch Health (2006) 2.38
Polarization and orientation of retinal ganglion cells in vivo. Neural Dev (2006) 1.89
Actomyosin is the main driver of interkinetic nuclear migration in the retina. Cell (2009) 1.84
Frizzled 5 signaling governs the neural potential of progenitors in the developing Xenopus retina. Neuron (2005) 1.80
From progenitors to differentiated cells in the vertebrate retina. Annu Rev Cell Dev Biol (2009) 1.76
Influences on neural lineage and mode of division in the zebrafish retina in vivo. J Cell Biol (2005) 1.75
Neurogenesis and the cell cycle. Neuron (2003) 1.75
In vivo time-lapse imaging of cell divisions during neurogenesis in the developing zebrafish retina. Neuron (2003) 1.74
Endocytosis-dependent desensitization and protein synthesis-dependent resensitization in retinal growth cone adaptation. Nat Neurosci (2005) 1.63
Mechanisms of ventral patterning in the vertebrate nervous system. Nat Rev Neurosci (2006) 1.49
Reconstruction of rat retinal progenitor cell lineages in vitro reveals a surprising degree of stochasticity in cell fate decisions. Development (2010) 1.48
How variable clones build an invariant retina. Neuron (2012) 1.47
Characterization and development of courtship in zebrafish, Danio rerio. Zebrafish (2004) 1.42
Hedgehog signaling and the retina: insights into the mechanisms controlling the proliferative properties of neural precursors. Genes Dev (2006) 1.40
Lineage in the vertebrate retina. Trends Neurosci (2006) 1.39
A novel function for Hedgehog signalling in retinal pigment epithelium differentiation. Development (2003) 1.36
XOtx5b and XOtx2 regulate photoreceptor and bipolar fates in the Xenopus retina. Development (2003) 1.35
Co-ordinating retinal histogenesis: early cell cycle exit enhances early cell fate determination in the Xenopus retina. Development (2002) 1.31
A directional Wnt/beta-catenin-Sox2-proneural pathway regulates the transition from proliferation to differentiation in the Xenopus retina. Development (2009) 1.28
Metabolic differentiation in the embryonic retina. Nat Cell Biol (2012) 1.25
Vsx2 in the zebrafish retina: restricted lineages through derepression. Neural Dev (2009) 1.23
Metabolism in physiological cell proliferation and differentiation. Trends Cell Biol (2013) 1.21
Dorsoventral patterning of the Xenopus eye: a collaboration of Retinoid, Hedgehog and FGF receptor signaling. Development (2005) 1.19
Ptf1a is expressed transiently in all types of amacrine cells in the embryonic zebrafish retina. Neural Dev (2009) 1.18
Apical migration of nuclei during G2 is a prerequisite for all nuclear motion in zebrafish neuroepithelia. Development (2011) 1.17
Youth risk behavior surveillance--Pacific Island United States Territories, 2007. MMWR Surveill Summ (2008) 1.16
Cep70 and Cep131 contribute to ciliogenesis in zebrafish embryos. BMC Cell Biol (2009) 1.14
The oriented emergence of axons from retinal ganglion cells is directed by laminin contact in vivo. Neuron (2011) 1.12
Youth Risk Behavior Surveillance--United States, 2003 (Abridged). J Sch Health (2004) 1.08
Youth Risk Behavior Surveillance - United States, 2015. MMWR Surveill Summ (2016) 1.07
A general role of hedgehog in the regulation of proliferation. Cell Cycle (2007) 1.07
Sexual Identity, Sex of Sexual Contacts, and Health-Related Behaviors Among Students in Grades 9-12 - United States and Selected Sites, 2015. MMWR Surveill Summ (2016) 1.04
RNA-binding protein Hermes/RBPMS inversely affects synapse density and axon arbor formation in retinal ganglion cells in vivo. J Neurosci (2013) 1.01
Coupling of NF-protocadherin signaling to axon guidance by cue-induced translation. Nat Neurosci (2013) 0.99
Lipofection strategy for the study of Xenopus retinal development. Methods (2002) 0.99
Origin and determination of inhibitory cell lineages in the vertebrate retina. J Neurosci (2011) 0.98
New views on retinal axon development: a navigation guide. Int J Dev Biol (2004) 0.97
Retinoic acid receptor signaling regulates choroid fissure closure through independent mechanisms in the ventral optic cup and periocular mesenchyme. Proc Natl Acad Sci U S A (2011) 0.96
Expression of Xenopus laevis Lhx2 during eye development and evidence for divergent expression among vertebrates. Dev Dyn (2006) 0.95
Molecular characterization of the GnRH system in zebrafish (Danio rerio): cloning of chicken GnRH-II, adult brain expression patterns and pituitary content of salmon GnRH and chicken GnRH-II. Gen Comp Endocrinol (2003) 0.95
The vertebrate retina: a model for neuronal polarization in vivo. Dev Neurobiol (2011) 0.94
Microcephaly models in the developing zebrafish retinal neuroepithelium point to an underlying defect in metaphase progression. Open Biol (2013) 0.93
Cellular requirements for building a retinal neuropil. Cell Rep (2013) 0.93
Youth risk behavior surveillance--selected steps communities, 2005. MMWR Surveill Summ (2007) 0.92
Tsukushi controls ectodermal patterning and neural crest specification in Xenopus by direct regulation of BMP4 and X-delta-1 activity. Development (2005) 0.91
Using myc genes to search for stem cells in the ciliary margin of the Xenopus retina. Dev Neurobiol (2012) 0.90
Slit1b-Robo3 signaling and N-cadherin regulate apical process retraction in developing retinal ganglion cells. J Neurosci (2012) 0.89
Time-lapse analysis of retinal differentiation. Curr Opin Cell Biol (2005) 0.89
Biasing amacrine subtypes in the Atoh7 lineage through expression of Barhl2. J Neurosci (2012) 0.87
Non-SMC condensin I complex proteins control chromosome segregation and survival of proliferating cells in the zebrafish neural retina. BMC Dev Biol (2009) 0.86
Youth risk behavior surveillance--selected Steps communities, United States, 2007. MMWR Surveill Summ (2008) 0.85
Multiple roles of Activin/Nodal, bone morphogenetic protein, fibroblast growth factor and Wnt/β-catenin signalling in the anterior neural patterning of adherent human embryonic stem cell cultures. Open Biol (2013) 0.83
Two zebrafish mutants, ebony and ivory, uncover benefits of neighborhood on photoreceptor survival. J Neurobiol (2003) 0.83
Induction and patterning of the telencephalon in Xenopus laevis. Development (2002) 0.83
A nutrient-sensitive restriction point is active during retinal progenitor cell differentiation. Development (2014) 0.83
Spectrum of Fates: a new approach to the study of the developing zebrafish retina. Development (2014) 0.82
Developmental biology: clocking the birth of neurons. Nature (2003) 0.77
Imaging retinal progenitor lineages in developing zebrafish embryos. Cold Spring Harb Protoc (2013) 0.77
Preparation of transgenic zebrafish embryos for imaging the developing retina. Cold Spring Harb Protoc (2013) 0.76
Progenitor competence: genes switching places. Cell (2013) 0.75
Overview and Methods for the Youth Risk Behavior Surveillance System - United States, 2019. MMWR Suppl (2020) 0.75
Specifying motor neurons: up and down and back to front. Nat Neurosci (2003) 0.75