Published in J Cell Sci on June 16, 2009
Tail-anchored membrane protein insertion into the endoplasmic reticulum. Nat Rev Mol Cell Biol (2011) 1.95
Bat3 promotes the membrane integration of tail-anchored proteins. J Cell Sci (2010) 1.71
Structural basis for tail-anchored membrane protein biogenesis by the Get3-receptor complex. Science (2011) 1.68
Biogenesis of tail-anchored proteins: the beginning for the end? J Cell Sci (2009) 1.64
Subcellular Partitioning of Protein Tyrosine Phosphatase 1B to the Endoplasmic Reticulum and Mitochondria Depends Sensitively on the Composition of Its Tail Anchor. PLoS One (2015) 1.44
Different effects of Sec61α, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells. J Cell Sci (2012) 1.15
Probing the spontaneous membrane insertion of a tail-anchored membrane protein by sum frequency generation spectroscopy. J Am Chem Soc (2010) 1.03
A biochemical analysis of the constraints of tail-anchored protein biogenesis. Biochem J (2011) 1.02
TRC40 can deliver short secretory proteins to the Sec61 translocon. J Cell Sci (2012) 0.97
Tail-anchored PEX26 targets peroxisomes via a PEX19-dependent and TRC40-independent class I pathway. J Cell Biol (2013) 0.97
Distinct pathways mediate the sorting of tail-anchored proteins to the plastid outer envelope. PLoS One (2010) 0.97
Tail-anchored membrane proteins: exploring the complex diversity of tail-anchored-protein targeting in plant cells. Plant Cell Rep (2010) 0.94
CDK5 regulatory subunit-associated protein 1-like 1 (CDKAL1) is a tail-anchored protein in the endoplasmic reticulum (ER) of insulinoma cells. J Biol Chem (2012) 0.92
Tail-anchored Protein Insertion in Mammals: FUNCTION AND RECIPROCAL INTERACTIONS OF THE TWO SUBUNITS OF THE TRC40 RECEPTOR. J Biol Chem (2016) 0.83
Ca2+-calmodulin inhibits tail-anchored protein insertion into the mammalian endoplasmic reticulum membrane. FEBS Lett (2011) 0.80
RPA and Rad51 constitute a cell intrinsic mechanism to protect the cytosol from self DNA. Nat Commun (2016) 0.80
CDK7 regulates the mitochondrial localization of a tail-anchored proapoptotic protein, Hid. Cell Rep (2013) 0.76
Asna1/TRC40 that mediates membrane insertion of tail-anchored proteins is required for efficient release of Herpes simplex virus 1 virions. Virol J (2016) 0.75
Targeting of tail-anchored membrane proteins to subcellular organelles in Toxoplasma gondii. Traffic (2016) 0.75
Formation of stacked ER cisternae by low affinity protein interactions. J Cell Biol (2003) 3.76
PI(4,5)P(2)-dependent and Ca(2+)-regulated ER-PM interactions mediated by the extended synaptotagmins. Cell (2013) 2.72
Molecular architecture of the human sinus node: insights into the function of the cardiac pacemaker. Circulation (2009) 2.58
Uncovering common principles in protein export of malaria parasites. Cell Host Microbe (2012) 2.16
Protection of Sinorhizobium against host cysteine-rich antimicrobial peptides is critical for symbiosis. PLoS Biol (2011) 1.92
Unassisted translocation of large polypeptide domains across phospholipid bilayers. J Cell Biol (2006) 1.69
Transmembrane topogenesis of a tail-anchored protein is modulated by membrane lipid composition. EMBO J (2005) 1.57
Trafficking of tail-anchored proteins: transport from the endoplasmic reticulum to the plasma membrane and sorting between surface domains in polarised epithelial cells. J Cell Sci (2002) 1.46
Exploiting the Burkholderia pseudomallei acute phase antigen BPSL2765 for structure-based epitope discovery/design in structural vaccinology. Chem Biol (2013) 1.45
Vascular damage and anti-angiogenic effects of tumor vessel-targeted liposomal chemotherapy. Cancer Res (2003) 1.45
Spontaneous formation of L-isoaspartate and gain of function in fibronectin. J Biol Chem (2006) 1.39
Transmembrane domain-dependent partitioning of membrane proteins within the endoplasmic reticulum. J Cell Biol (2008) 1.38
Targeting liposomal chemotherapy via both tumor cell-specific and tumor vasculature-specific ligands potentiates therapeutic efficacy. Cancer Res (2006) 1.37
Cancer immunotherapy based on killing of Salmonella-infected tumor cells. Cancer Res (2005) 1.28
Translocation of the C terminus of a tail-anchored protein across the endoplasmic reticulum membrane in yeast mutants defective in signal peptide-driven translocation. J Biol Chem (2002) 1.27
PHOX2B regulates its own expression by a transcriptional auto-regulatory mechanism. J Biol Chem (2005) 1.26
Structure-activity relationships of linear and cyclic peptides containing the NGR tumor-homing motif. J Biol Chem (2002) 1.22
Carcinoembryonic antigen-specific but not antiviral CD4+ T cell immunity is impaired in pancreatic carcinoma patients. J Immunol (2008) 1.18
Enhanced antitumor efficacy of clinical-grade vasculature-targeted liposomal doxorubicin. Clin Cancer Res (2008) 1.14
N-myristoylation determines dual targeting of mammalian NADH-cytochrome b5 reductase to ER and mitochondrial outer membranes by a mechanism of kinetic partitioning. J Cell Biol (2005) 1.14
A VAPB mutant linked to amyotrophic lateral sclerosis generates a novel form of organized smooth endoplasmic reticulum. FASEB J (2009) 1.13
Coupling tumor necrosis factor-alpha with alphaV integrin ligands improves its antineoplastic activity. Cancer Res (2004) 1.12
Serum IgA of HIV-exposed uninfected individuals inhibit HIV through recognition of a region within the alpha-helix of gp41. AIDS (2002) 1.09
Distribution of the pacemaker HCN4 channel mRNA and protein in the rabbit sinoatrial node. J Mol Cell Cardiol (2009) 1.09
Selective activation of the transcription factor ATF6 mediates endoplasmic reticulum proliferation triggered by a membrane protein. Proc Natl Acad Sci U S A (2011) 1.07
The P2Y-like receptor GPR17 as a sensor of damage and a new potential target in spinal cord injury. Brain (2009) 1.07
Nicotinic acetylcholine receptor subtypes expression during rat retina development and their regulation by visual experience. Mol Pharmacol (2004) 1.07
Selective nicotinic acetylcholine receptor subunit deficits identified in Alzheimer's disease, Parkinson's disease and dementia with Lewy bodies by immunoprecipitation. Neurobiol Dis (2006) 1.06
Host plant peptides elicit a transcriptional response to control the Sinorhizobium meliloti cell cycle during symbiosis. Proc Natl Acad Sci U S A (2014) 1.06
Critical role of flanking residues in NGR-to-isoDGR transition and CD13/integrin receptor switching. J Biol Chem (2010) 1.05
KDEL and KKXX retrieval signals appended to the same reporter protein determine different trafficking between endoplasmic reticulum, intermediate compartment, and Golgi complex. Mol Biol Cell (2003) 1.04
Leucine-zipper-mediated homo- and hetero-dimerization of GIT family p95-ARF GTPase-activating protein, PIX-, paxillin-interacting proteins 1 and 2. Biochem J (2003) 1.04
Structural basis for the interaction of isoDGR with the RGD-binding site of alphavbeta3 integrin. J Biol Chem (2008) 1.03
Long-lasting CCR5 internalization by antibodies in a subset of long-term nonprogressors: a possible protective effect against disease progression. Blood (2006) 1.03
Two tail-anchored protein variants, differing in transmembrane domain length and intracellular sorting, interact differently with lipids. Proc Natl Acad Sci U S A (2005) 1.03
The low-affinity receptor for neurotrophins p75NTR plays a key role for satellite cell function in muscle repair acting via RhoA. Mol Biol Cell (2009) 1.02
Non-redundant role for IL-12 and IL-27 in modulating Th2 polarization of carcinoembryonic antigen specific CD4 T cells from pancreatic cancer patients. PLoS One (2009) 1.00
Cell culture models to investigate the selective vulnerability of motoneuronal mitochondria to familial ALS-linked G93ASOD1. Eur J Neurosci (2006) 0.99
Dynamic and reversible restructuring of the ER induced by PDMP in cultured cells. J Cell Sci (2006) 0.99
Decrease and dysfunction of dendritic cells correlate with impaired hepatitis C virus-specific CD4+ T-cell proliferation in patients with hepatitis C virus infection. Immunology (2007) 0.98
IFN-gamma produced by human papilloma virus-18 E6-specific CD4+ T cells predicts the clinical outcome after surgery in patients with high-grade cervical lesions. J Immunol (2007) 0.98
Isoaspartate-glycine-arginine: a new tumor vasculature-targeting motif. Cancer Res (2008) 0.97
Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma. J Control Release (2010) 0.96
Lymphocyte subset patterns and cytokine production in Alzheimer's disease patients. Neurobiol Aging (2006) 0.93
Decrease in pathology and progression of scrapie after immunisation with synthetic prion protein peptides in hamsters. Vaccine (2005) 0.93
Booster vaccinations against cancer are critical in prophylactic but detrimental in therapeutic settings. Cancer Res (2013) 0.93
CDK5 regulatory subunit-associated protein 1-like 1 (CDKAL1) is a tail-anchored protein in the endoplasmic reticulum (ER) of insulinoma cells. J Biol Chem (2012) 0.92
Role of cysteine residues and disulfide bonds in the activity of a legume root nodule-specific, cysteine-rich peptide. J Biol Chem (2012) 0.91
MAB21L2, a vertebrate member of the Male-abnormal 21 family, modulates BMP signaling and interacts with SMAD1. BMC Cell Biol (2004) 0.91
Activation of endothelial nitric-oxide synthase by tumor necrosis factor-alpha: a novel pathway involving sequential activation of neutral sphingomyelinase, phosphatidylinositol-3' kinase, and Akt. Mol Pharmacol (2003) 0.91
CD4(+) T cells from healthy subjects and colon cancer patients recognize a carcinoembryonic antigen-specific immunodominant epitope. Cancer Res (2003) 0.91
Nicotine-modulated subunit stoichiometry affects stability and trafficking of α3β4 nicotinic receptor. J Neurosci (2013) 0.91
Breakdown of tolerance to a self-peptide of acetylcholine receptor alpha-subunit induces experimental myasthenia gravis in rats. J Immunol (2004) 0.90
Immunogenic and structural properties of the Asn-Gly-Arg (NGR) tumor neovasculature-homing motif. Mol Immunol (2005) 0.90
High sensitivity protein assays on microarray silicon slides. Anal Chem (2009) 0.90
Transcription factor PHOX2A regulates the human alpha3 nicotinic receptor subunit gene promoter. J Biol Chem (2007) 0.90
Kinetics of contact formation and end-to-end distance distributions of swollen disordered peptides. Biophys J (2009) 0.90
Endosomal proteases influence the repertoire of MAGE-A3 epitopes recognized in vivo by CD4+ T cells. Cancer Res (2008) 0.88
Endothelial nitric oxide synthase is segregated from caveolin-1 and localizes to the leading edge of migrating cells. Exp Cell Res (2006) 0.88
CD4+CD25+FoxP3+PD1- regulatory T cells in acute and stable relapsing-remitting multiple sclerosis and their modulation by therapy. FASEB J (2008) 0.88
Molecular engineering of RANTES peptide mimetics with potent anti-HIV-1 activity. FASEB J (2011) 0.86
Localization of synaptic proteins involved in neurosecretion in different membrane microdomains. J Neurochem (2006) 0.86
Engineering of α-conotoxin MII-derived peptides with increased selectivity for native α6β2* nicotinic acetylcholine receptors. FASEB J (2011) 0.86
An o-nitrobenzyl scaffold for peptide ligation: synthesis and applications. Bioorg Med Chem (2004) 0.85
Hepatitis C virus-specific reactivity of CD4+-lymphocytes in children born from HCV-infected women. J Hepatol (2005) 0.85
Rational epitope design for protein targeting. ACS Chem Biol (2012) 0.85
A structure-based strategy for epitope discovery in Burkholderia pseudomallei OppA antigen. Structure (2012) 0.84
Basal nitric oxide release attenuates cell migration of HeLa and endothelial cells. Biochem Biophys Res Commun (2009) 0.84
Chronic deficiency of nitric oxide affects hypoxia inducible factor-1α (HIF-1α) stability and migration in human endothelial cells. PLoS One (2011) 0.84
Novel phage display-derived neuroblastoma-targeting peptides potentiate the effect of drug nanocarriers in preclinical settings. J Control Release (2013) 0.84
Restructured endoplasmic reticulum generated by mutant amyotrophic lateral sclerosis-linked VAPB is cleared by the proteasome. J Cell Sci (2012) 0.83
Liposome-mediated therapy of neuroblastoma. Methods Enzymol (2009) 0.83
IsoDGR-tagged albumin: a new αvβ3 selective carrier for nanodrug delivery to tumors. Small (2012) 0.83
Critical role of the N-loop and beta1-strand hydrophobic clusters of RANTES-derived peptides in anti-HIV activity. Biochem Biophys Res Commun (2006) 0.82
CD4+ T cells against human papillomavirus-18 E7 in patients with high-grade cervical lesions associate with the absence of the virus in the cervix. Immunology (2010) 0.81
Enhancement of anti-HIV-1 activity by hot spot evolution of RANTES-derived peptides. Chem Biol (2012) 0.81
Myelin basic protein-specific T lymphocytes proliferation and programmed cell death in demyelinating diseases. Clin Immunol (2008) 0.81
Broad-spectrum inhibition of HIV-1 by a monoclonal antibody directed against a gp120-induced epitope of CD4. PLoS One (2011) 0.81
The CD4+ T-cell epitope-binding register is a critical parameter when generating functional HLA-DR tetramers with promiscuous peptides. Eur J Immunol (2010) 0.81
Characterization of a monoclonal antibody specific for novel Bcr/Abl out-of-frame fusion proteins. Hybridoma (Larchmt) (2011) 0.80
Cleavage of chromogranin A N-terminal domain by plasmin provides a new mechanism for regulating cell adhesion. J Biol Chem (2002) 0.80
T-cell receptor-mediated cross-allergenicity. Int Arch Allergy Immunol (2004) 0.80
Two amino acid substitutions within the first external loop of CCR5 induce human immunodeficiency virus-blocking antibodies in mice and chickens. J Virol (2008) 0.80
Chromogranin A N-terminal fragments vasostatin-1 and the synthetic CGA 7-57 peptide act as cardiostatins on the isolated working frog heart. Gen Comp Endocrinol (2004) 0.80
Identification of novel subdominant epitopes on the carcinoembryonic antigen recognized by CD4+ T cells of lung cancer patients. J Immunol (2006) 0.80
Peptide models of folding initiation sites of bovine beta-lactoglobulin: identification of nativelike hydrophobic interactions involving G and H strands. Biochemistry (2002) 0.79
Homogeneous immunoassay of atrazine in water by terbium-entrapping liposomes as fluorescent markers. Talanta (2003) 0.79
In search of a vaccine for mouse allergy: significant reduction of Mus m 1 allergenicity by structure-guided single-point mutations. Int Arch Allergy Immunol (2011) 0.79
A cellular system to study the role of nitric oxide in cell death, survival, and migration. Neurotoxicology (2005) 0.78
Structure determination and dynamics of peptides overlapping the catalytic hairpin of the Ras-specific GEF Cdc25(Mm). Biochemistry (2003) 0.78
Chicken ileal bile-acid-binding protein: a promising target of investigation to understand binding co-operativity across the protein family. Biochem J (2009) 0.78
Chromogranin A binds to αvβ6-integrin and promotes wound healing in mice. Cell Mol Life Sci (2012) 0.78
MAGE-A3(161-175) contains an HLA-DRbeta4 restricted natural epitope poorly formed through indirect presentation by dendritic cells. Cancer Immunol Immunother (2007) 0.78
NMR-based modeling and binding studies of a ternary complex between chicken liver bile acid binding protein and bile acids. Proteins (2007) 0.78
Epitope mapping of human chromogranin A by peptide microarrays. Methods Mol Biol (2009) 0.78
Peptide microarrays for the characterization of antigenic regions of human chromogranin A. Proteomics (2005) 0.78
Role of vasostatin-1 C-terminal region in fibroblast cell adhesion. Cell Mol Life Sci (2010) 0.77