Cytotoxic triterpenoids from the stems of Microtropis japonica.

PubWeight™: 0.81‹?›

🔗 View Article (PMID 19534471)

Published in J Nat Prod on July 01, 2009

Authors

I-Hsiao Chen1, Mei-Chin Lu, Ying-Chi Du, Ming-Hong Yen, Chin-Chung Wu, Yung-Husan Chen, Chih-Sheng Hung, Shu-Li Chen, Fang-Rong Chang, Yang-Chang Wu

Author Affiliations

1: Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan, Republic of China.

Articles by these authors

Potent inhibition of superoxide anion production in activated human neutrophils by isopedicin, a bioactive component of the Chinese medicinal herb Fissistigma oldhamii. Free Radic Biol Med (2008) 1.87

The influence of type 2 diabetes and glucose-lowering therapies on cancer risk in the Taiwanese. Exp Diabetes Res (2012) 1.53

Cladielloides A and B: new eunicellin-type diterpenoids from an Indonesian octocoral Cladiella sp. Mar Drugs (2010) 1.50

The hederagenin saponin SMG-1 is a natural FMLP receptor inhibitor that suppresses human neutrophil activation. Biochem Pharmacol (2010) 1.47

A new anti-HIV alkaloid, drymaritin, and a new C-glycoside flavonoid, diandraflavone, from Drymaria diandra. J Nat Prod (2004) 1.42

Antitumor agents. 250. Design and synthesis of new curcumin analogues as potential anti-prostate cancer agents. J Med Chem (2006) 1.42

Eunicellin-based diterpenoids, australins A-D, isolated from the soft coral Cladiella australis. J Nat Prod (2005) 1.36

Cytotoxic and anti-inflammatory cembranoids from the soft coral Lobophytum crassum. J Nat Prod (2008) 1.33

Discovery of new eunicellins from an Indonesian octocoral Cladiella sp. Mar Drugs (2011) 1.32

Paralemnolins J-P, new sesquiterpenoids from the soft coral Paralemnalia thyrsoide. Chem Pharm Bull (Tokyo) (2010) 1.30

Anti-AIDS agents 69. Moronic acid and other triterpene derivatives as novel potent anti-HIV agents. J Med Chem (2006) 1.25

Klysimplexins I-T, eunicellin-based diterpenoids from the cultured soft coral Klyxum simplex. Org Biomol Chem (2010) 1.25

Synthesis of chalcone derivatives as potential anti-diabetic agents. Bioorg Med Chem Lett (2012) 1.25

Hirsutalins A-H, eunicellin-based diterpenoids from the soft coral Cladiella hirsuta. J Nat Prod (2010) 1.23

Antioxidant activities of extracts and main components of Pigeonpea [Cajanus cajan (L.) Millsp.] leaves. Molecules (2009) 1.23

Marine algal natural products with anti-oxidative, anti-inflammatory, and anti-cancer properties. Cancer Cell Int (2013) 1.19

Crassolides A-F, cembranoids with a trans-fused lactone from the soft coral Sarcophyton crassocaule. J Nat Prod (2006) 1.18

The hepatoprotective effects of Limonium sinense against carbon tetrachloride and beta-D-galactosamine intoxication in rats. Phytother Res (2003) 1.18

Bioactive cembranoids from the soft coral Sinularia crassa. Mar Drugs (2011) 1.18

Gallic acid, a major component of Toona sinensis leaf extracts, contains a ROS-mediated anti-cancer activity in human prostate cancer cells. Cancer Lett (2009) 1.18

Hirsutosterols A-G, polyoxygenated steroids from a Formosan soft coral Cladiella hirsuta. Org Biomol Chem (2011) 1.16

Anti-proliferative effect of methanolic extract of Gracilaria tenuistipitata on oral cancer cells involves apoptosis, DNA damage, and oxidative stress. BMC Complement Altern Med (2012) 1.12

Oxygenated cembranoids from a Formosan soft coral Sinularia gibberosa. J Nat Prod (2008) 1.12

Soluble guanylyl cyclase activator YC-1 inhibits human neutrophil functions through a cGMP-independent but cAMP-dependent pathway. Mol Pharmacol (2003) 1.11

Pristimerin induces caspase-dependent apoptosis in MDA-MB-231 cells via direct effects on mitochondria. Mol Cancer Ther (2005) 1.11

Klymollins A-H, bioactive eunicellin-based diterpenoids from the formosan soft coral Klyxum molle. J Nat Prod (2011) 1.11

Euphol from Euphorbia tirucalli selectively inhibits human gastric cancer cell growth through the induction of ERK1/2-mediated apoptosis. Food Chem Toxicol (2012) 1.10

Recent research and development of Antrodia cinnamomea. Pharmacol Ther (2013) 1.09

Involvement of store-operated calcium signaling in EGF-mediated COX-2 gene activation in cancer cells. Cell Signal (2011) 1.09

Automatic morphological subtyping reveals new roles of caspases in mitochondrial dynamics. PLoS Comput Biol (2011) 1.08

Emodin-induced apoptosis through p53-dependent pathway in human hepatoma cells. Life Sci (2004) 1.08

Antitumor agents. 228. five new agarofurans, Reissantins A-E, and cytotoxic principles from Reissantia buchananii. J Nat Prod (2003) 1.07

Association of ORAI1 haplotypes with the risk of HLA-B27 positive ankylosing spondylitis. PLoS One (2011) 1.07

Influenza A (H(1)N(1)) Antiviral and Cytotoxic Agents from Ferula assa-foetida. J Nat Prod (2009) 1.06

4beta-Hydroxywithanolide E from Physalis peruviana (golden berry) inhibits growth of human lung cancer cells through DNA damage, apoptosis and G2/M arrest. BMC Cancer (2010) 1.06

Acetogenins as selective inhibitors of the human ovarian 1A9 tumor cell line. J Med Chem (2003) 1.05

Antiproliferation and induction of apoptosis in Ca9-22 oral cancer cells by ethanolic extract of Gracilaria tenuistipitata. Molecules (2012) 1.05

(-)-Hydroxylindestrenolide, a new sesquiterpenoid from a gorgonian coral Menella sp. (Plexauridae). Chem Pharm Bull (Tokyo) (2011) 1.04

Antiproliferative effects of goniothalamin on Ca9-22 oral cancer cells through apoptosis, DNA damage and ROS induction. Mutat Res (2012) 1.03

Paraminabeolides A-F, cytotoxic and anti-inflammatory marine withanolides from the soft coral Paraminabea acronocephala. J Nat Prod (2011) 1.02

Steroids from the soft coral Sinularia crassa. Mar Drugs (2012) 1.02

New ent-kaurane diterpenoids with anti-platelet aggregation activity from Annona squamosa. J Nat Prod (2002) 1.00

Goniothalamin inhibits growth of human lung cancer cells through DNA damage, apoptosis, and reduced migration ability. J Agric Food Chem (2011) 1.00

Inhibitory effects of 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose on biofilm formation by Staphylococcus aureus. Antimicrob Agents Chemother (2010) 0.99

Natural product chemistry of gorgonian corals of genus Junceella--part II. Mar Drugs (2011) 0.99

Glycolipids from the formosan soft coral Lobophytum crassum. Chem Pharm Bull (Tokyo) (2007) 0.99

Towards the small and the beautiful: a small dibromotyrosine derivative from Pseudoceratina sp. sponge exhibits potent apoptotic effect through targeting IKK/NFκB signaling pathway. Mar Drugs (2013) 0.99

Polyoxygenated steroids from the gorgonian Isis hippuris. J Nat Prod (2005) 0.98

Cladieunicellins K and L, new eunicellin-based diterpenoids from an octocoral Cladiella sp. Int J Mol Sci (2013) 0.98

Fern plant-derived protoapigenone leads to DNA damage, apoptosis, and G(2)/m arrest in lung cancer cell line H1299. DNA Cell Biol (2009) 0.97

An epigenetic modifier enhances the production of anti-diabetic and anti-inflammatory sesquiterpenoids from Aspergillus sydowii. Bioorg Med Chem (2013) 0.97

Anti-hepatitis C virus activity of Acacia confusa extract via suppressing cyclooxygenase-2. Antiviral Res (2010) 0.97

Tubocapsenolide A, a novel withanolide, inhibits proliferation and induces apoptosis in MDA-MB-231 cells by thiol oxidation of heat shock proteins. J Biol Chem (2008) 0.97

Anti-inflammatory constituents and new pterocarpanoid of Crotalaria pallida. J Nat Prod (2003) 0.96

Cytotoxic and anti-inflammatory metabolites from the soft coral Scleronephthya gracillimum. Mar Drugs (2013) 0.96

First total synthesis of protoapigenone and its analogues as potent cytotoxic agents. J Med Chem (2007) 0.96

New cytotoxic flavonoids from Thelypteris torresiana. Planta Med (2005) 0.96

Discovery of new eunicellin-based diterpenoids from a Formosan soft coral Cladiella sp. Mar Drugs (2013) 0.95

Huang-lian-jie-du-tang, a traditional Chinese medicine prescription, induces cell-cycle arrest and apoptosis in human liver cancer cells in vitro and in vivo. J Gastroenterol Hepatol (2008) 0.95

New cytotoxic cyclic peptides and dianthramide from Dianthus superbus. J Nat Prod (2004) 0.95

Cytotoxic calanquinone A from Calanthe arisanensis and its first total synthesis. Bioorg Med Chem Lett (2008) 0.95

9,11-Secosterols from the soft corals Sinularia lochmodes and Sinularia leptoclados. J Nat Prod (2006) 0.95

A C-3 methylated isocembranoid and 10-oxocembranoids from a formosan soft coral, Sinularia grandilobata. J Nat Prod (2008) 0.95

Baicalin-induced apoptosis is mediated by Bcl-2-dependent, but not p53-dependent, pathway in human leukemia cell lines. Am J Chin Med (2006) 0.94

Synthesis and pharmacological evaluation of novel beta-nitrostyrene derivatives as tyrosine kinase inhibitors with potent antiplatelet activity. Biochem Pharmacol (2007) 0.94

Historic perspectives on Annonaceous acetogenins from the chemical bench to preclinical trials. Planta Med (2010) 0.93