Published in BMC Genomics on June 17, 2009
Host-mediated regulation of superinfection in malaria. Nat Med (2011) 2.57
A microscale human liver platform that supports the hepatic stages of Plasmodium falciparum and vivax. Cell Host Microbe (2013) 1.95
Host cell phosphatidylcholine is a key mediator of malaria parasite survival during liver stage infection. Cell Host Microbe (2014) 1.66
Suppression of host p53 is critical for Plasmodium liver-stage infection. Cell Rep (2013) 1.08
Pre-erythrocytic malaria vaccines: identifying the targets. Expert Rev Vaccines (2012) 1.07
Transition of Plasmodium sporozoites into liver stage-like forms is regulated by the RNA binding protein Pumilio. PLoS Pathog (2011) 1.06
Malaria parasite pre-erythrocytic infection: preparation meets opportunity. Cell Microbiol (2012) 1.06
Torins are potent antimalarials that block replenishment of Plasmodium liver stage parasitophorous vacuole membrane proteins. Proc Natl Acad Sci U S A (2013) 1.05
Targeting lipid biosynthesis and salvage in apicomplexan parasites for improved chemotherapies. Nat Rev Microbiol (2013) 0.98
Long-term live imaging reveals cytosolic immune responses of host hepatocytes against Plasmodium infection and parasite escape mechanisms. Autophagy (2015) 0.96
Quantification of sporozoite invasion, migration, and development by microscopy and flow cytometry. Methods Mol Biol (2013) 0.92
New Agilent platform DNA microarrays for transcriptome analysis of Plasmodium falciparum and Plasmodium berghei for the malaria research community. Malar J (2012) 0.90
Parasite-induced ER stress response in hepatocytes facilitates Plasmodium liver stage infection. EMBO Rep (2015) 0.90
The quality of methods reporting in parasitology experiments. PLoS One (2014) 0.88
Pathogens hijack the epigenome: a new twist on host-pathogen interactions. Am J Pathol (2014) 0.88
A key role for lipoic acid synthesis during Plasmodium liver stage development. Cell Microbiol (2013) 0.87
CSP--a model for in vivo presentation of Plasmodium berghei sporozoite antigens by hepatocytes. PLoS One (2012) 0.87
The avian transcriptome response to malaria infection. Mol Biol Evol (2015) 0.85
Metamorphoses of malaria: the role of autophagy in parasite differentiation. Essays Biochem (2011) 0.85
Early transcriptional responses of HepG2-A16 liver cells to infection by Plasmodium falciparum sporozoites. J Biol Chem (2011) 0.83
Susceptibility to Plasmodium liver stage infection is altered by hepatocyte polyploidy. Cell Microbiol (2014) 0.83
Host-based Prophylaxis Successfully Targets Liver Stage Malaria Parasites. Mol Ther (2015) 0.82
Discovery of Novel Plasmodium falciparum Pre-Erythrocytic Antigens for Vaccine Development. PLoS One (2015) 0.82
Eimeria falciformis infection of the mouse caecum identifies opposing roles of IFNγ-regulated host pathways for the parasite development. Mucosal Immunol (2013) 0.81
Priming of CD8(+) T Cell Responses to Liver Stage Malaria Parasite Antigens. Front Immunol (2014) 0.81
GLUT1-mediated glucose uptake plays a crucial role during Plasmodium hepatic infection. Cell Microbiol (2016) 0.79
Highly dynamic host actin reorganization around developing Plasmodium inside hepatocytes. PLoS One (2012) 0.79
Hepcidin and iron-mediated resistance to malaria. EMBO Mol Med (2011) 0.78
A Sporozoite- and Liver Stage-expressed Tryptophan-rich Protein Plays an Auxiliary Role in Plasmodium Liver Stage Development and Is a Potential Vaccine Candidate. J Biol Chem (2015) 0.78
Recent advances in understanding apicomplexan parasites. F1000Res (2016) 0.77
Stress granules and Plasmodium liver stage infection. Biol Open (2014) 0.76
Selection and refinement: the malaria parasite's infection and exploitation of host hepatocytes. Curr Opin Microbiol (2015) 0.76
Uptake and metabolism of arginine impact Plasmodium development in the liver. Sci Rep (2017) 0.75
In vitro alterations do not reflect a requirement for host cell cycle progression during Plasmodium liver stage infection. Eukaryot Cell (2014) 0.75
Plasmodium berghei EXP-1 interacts with host Apolipoprotein H during Plasmodium liver-stage development. Proc Natl Acad Sci U S A (2017) 0.75
Expanding the antimalarial toolkit: Targeting host-parasite interactions. J Exp Med (2016) 0.75
A novel FIKK kinase regulates the development of mosquito and liver stages of the malaria. Sci Rep (2016) 0.75
Host AMPK Is a Modulator of Plasmodium Liver Infection. Cell Rep (2016) 0.75
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Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics (2003) 100.88
Using GOstats to test gene lists for GO term association. Bioinformatics (2006) 12.58
The limits and intensity of Plasmodium falciparum transmission: implications for malaria control and elimination worldwide. PLoS Med (2008) 8.95
limmaGUI: a graphical user interface for linear modeling of microarray data. Bioinformatics (2004) 6.04
A Plasmodium berghei reference line that constitutively expresses GFP at a high level throughout the complete life cycle. Mol Biochem Parasitol (2004) 5.80
TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver. Science (2003) 5.25
High-efficiency transfection and drug selection of genetically transformed blood stages of the rodent malaria parasite Plasmodium berghei. Nat Protoc (2006) 4.19
Migration of Plasmodium sporozoites through cells before infection. Science (2001) 3.89
A combined transcriptome and proteome survey of malaria parasite liver stages. Proc Natl Acad Sci U S A (2008) 3.56
The silent path to thousands of merozoites: the Plasmodium liver stage. Nat Rev Microbiol (2006) 2.83
Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation. J Biol Chem (2001) 2.65
Apoptotic Plasmodium-infected hepatocytes provide antigens to liver dendritic cells. J Infect Dis (2005) 2.42
Intravital observation of Plasmodium berghei sporozoite infection of the liver. PLoS Biol (2005) 2.32
Mycobacterium tuberculosis senses host-derived carbon monoxide during macrophage infection. Cell Host Microbe (2008) 2.24
The central role of glutathione in the pathophysiology of human diseases. Arch Physiol Biochem (2007) 2.12
Hepatitis C virus core triggers apoptosis in liver cells by inducing ER stress and ER calcium depletion. Oncogene (2005) 2.02
The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells. Cancer Cell (2006) 1.85
Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver. Proc Natl Acad Sci U S A (2001) 1.84
Screening for Toxoplasma gondii-regulated transcriptional responses in lipopolysaccharide-activated macrophages. Infect Immun (2006) 1.67
Comparison of gene expression profiles between hepatitis B virus- and hepatitis C virus-infected hepatocellular carcinoma by oligonucleotide microarray data on the basis of a supervised learning method. Cancer Res (2002) 1.64
Heme oxygenase-1 is an anti-inflammatory host factor that promotes murine plasmodium liver infection. Cell Host Microbe (2008) 1.62
Dissecting in vitro host cell infection by Plasmodium sporozoites using flow cytometry. Cell Microbiol (2007) 1.50
Host scavenger receptor SR-BI plays a dual role in the establishment of malaria parasite liver infection. Cell Host Microbe (2008) 1.50
L-FABP is a critical host factor for successful malaria liver stage development. Int J Parasitol (2007) 1.48
The human zinc transporter SLC39A8 (Zip8) is critical in zinc-mediated cytoprotection in lung epithelia. Am J Physiol Lung Cell Mol Physiol (2008) 1.45
Toxoplasma gondii dysregulates IFN-gamma-inducible gene expression in human fibroblasts: insights from a genome-wide transcriptional profiling. J Immunol (2007) 1.44
The liver stage of Plasmodium berghei inhibits host cell apoptosis. Mol Microbiol (2005) 1.40
Hepatocyte growth factor and its receptor are required for malaria infection. Nat Med (2003) 1.37
Antiviral activity and hepatoprotection by heme oxygenase-1 in hepatitis B virus infection. Gastroenterology (2007) 1.32
HGF/MET signalling protects Plasmodium-infected host cells from apoptosis. Cell Microbiol (2005) 1.28
Transformation of sporozoites into early exoerythrocytic malaria parasites does not require host cells. J Exp Med (2003) 1.26
Simvastatin triggers mitochondria-induced Ca2+ signaling alteration in skeletal muscle. Biochem Biophys Res Commun (2005) 1.24
Kinome-wide RNAi screen implicates at least 5 host hepatocyte kinases in Plasmodium sporozoite infection. PLoS Pathog (2008) 1.20
Host and parasite-derived IKK activities direct distinct temporal phases of NF-kappaB activation and target gene expression following Toxoplasma gondii infection. J Cell Sci (2005) 1.17
Stage-specific transcription of distinct repertoires of a multigene family during Plasmodium life cycle. Science (2002) 1.14
In vivo imaging enters parasitology. Trends Parasitol (2006) 1.05
Initiation and termination of NF-kappaB signaling by the intracellular protozoan parasite Toxoplasma gondii. J Cell Sci (2005) 1.04
Infection with Toxoplasma gondii bradyzoites has a diminished impact on host transcript levels relative to tachyzoite infection. Infect Immun (2006) 0.94
Plasmodium yoelii: efficient in vitro invasion and complete development of sporozoites in mouse hepatic cell lines. Exp Parasitol (2000) 0.93
Sporozoite-mediated hepatocyte wounding limits Plasmodium parasite development via MyD88-mediated NF-kappa B activation and inducible NO synthase expression. J Immunol (2008) 0.93
The skin stage of malaria infection: biology and relevance to the malaria vaccine effort. Future Microbiol (2008) 0.92
Antimalarial drugs - host targets (re)visited. Biotechnol J (2006) 0.92
Malaria: progress, perils, and prospects for eradication. J Clin Invest (2008) 6.54
Genetically modified Plasmodium parasites as a protective experimental malaria vaccine. Nature (2004) 4.35
Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria. Nat Med (2007) 4.22
A combined transcriptome and proteome survey of malaria parasite liver stages. Proc Natl Acad Sci U S A (2008) 3.56
Plasmodium liver stage developmental arrest by depletion of a protein at the parasite-host interface. Proc Natl Acad Sci U S A (2005) 3.06
The silent path to thousands of merozoites: the Plasmodium liver stage. Nat Rev Microbiol (2006) 2.83
Murine malaria parasite sequestration: CD36 is the major receptor, but cerebral pathology is unlinked to sequestration. Proc Natl Acad Sci U S A (2005) 2.71
Host-mediated regulation of superinfection in malaria. Nat Med (2011) 2.57
Genetically attenuated, P36p-deficient malarial sporozoites induce protective immunity and apoptosis of infected liver cells. Proc Natl Acad Sci U S A (2005) 2.49
Type II fatty acid synthesis is essential only for malaria parasite late liver stage development. Cell Microbiol (2008) 2.49
Lethal influenza virus infection in macaques is associated with early dysregulation of inflammatory related genes. PLoS Pathog (2009) 2.44
Apoptotic Plasmodium-infected hepatocytes provide antigens to liver dendritic cells. J Infect Dis (2005) 2.42
Visualisation and quantitative analysis of the rodent malaria liver stage by real time imaging. PLoS One (2009) 2.18
Protracted sterile protection with Plasmodium yoelii pre-erythrocytic genetically attenuated parasite malaria vaccines is independent of significant liver-stage persistence and is mediated by CD8+ T cells. J Infect Dis (2007) 1.99
A microscale human liver platform that supports the hepatic stages of Plasmodium falciparum and vivax. Cell Host Microbe (2013) 1.95
Splicing enhances recruitment of methyltransferase HYPB/Setd2 and methylation of histone H3 Lys36. Nat Struct Mol Biol (2011) 1.85
Myosin A tail domain interacting protein (MTIP) localizes to the inner membrane complex of Plasmodium sporozoites. J Cell Sci (2003) 1.85
Infectivity-associated changes in the transcriptional repertoire of the malaria parasite sporozoite stage. J Biol Chem (2002) 1.83
Quantitative isolation and in vivo imaging of malaria parasite liver stages. Int J Parasitol (2006) 1.83
Plasmodium yoelii sporozoites with simultaneous deletion of P52 and P36 are completely attenuated and confer sterile immunity against infection. Infect Immun (2007) 1.79
Genetically attenuated Plasmodium berghei liver stages induce sterile protracted protection that is mediated by major histocompatibility complex Class I-dependent interferon-gamma-producing CD8+ T cells. J Infect Dis (2007) 1.79
Malaria blood stage suppression of liver stage immunity by dendritic cells. J Exp Med (2003) 1.78
Differential transcriptome profiling identifies Plasmodium genes encoding pre-erythrocytic stage-specific proteins. Mol Microbiol (2004) 1.76
Compression of next-generation sequencing reads aided by highly efficient de novo assembly. Nucleic Acids Res (2012) 1.76
Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design. Proc Natl Acad Sci U S A (2009) 1.72
A specific inhibitor of PfCDPK4 blocks malaria transmission: chemical-genetic validation. J Infect Dis (2013) 1.71
Release of hepatic Plasmodium yoelii merozoites into the pulmonary microvasculature. PLoS Pathog (2007) 1.67
Heme oxygenase-1 is an anti-inflammatory host factor that promotes murine plasmodium liver infection. Cell Host Microbe (2008) 1.62
Superior antimalarial immunity after vaccination with late liver stage-arresting genetically attenuated parasites. Cell Host Microbe (2011) 1.61
Targeted deletion of SAP1 abolishes the expression of infectivity factors necessary for successful malaria parasite liver infection. Mol Microbiol (2008) 1.56
Real-time quantitative reverse transcription PCR for monitoring of blood-stage Plasmodium falciparum infections in malaria human challenge trials. Am J Trop Med Hyg (2012) 1.55
MicroRNA expression and virulence in pandemic influenza virus-infected mice. J Virol (2010) 1.54
Complete Plasmodium falciparum liver-stage development in liver-chimeric mice. J Clin Invest (2012) 1.52
Malaria parasite development in the mosquito and infection of the mammalian host. Annu Rev Microbiol (2009) 1.52
Dissecting in vitro host cell infection by Plasmodium sporozoites using flow cytometry. Cell Microbiol (2007) 1.50
Genetically engineered, attenuated whole-cell vaccine approaches for malaria. Hum Vaccin (2010) 1.50
Host scavenger receptor SR-BI plays a dual role in the establishment of malaria parasite liver infection. Cell Host Microbe (2008) 1.50
L-FABP is a critical host factor for successful malaria liver stage development. Int J Parasitol (2007) 1.48
Accumulation of Plasmodium berghei-infected red blood cells in the brain is crucial for the development of cerebral malaria in mice. Infect Immun (2010) 1.47
Lethal dissemination of H5N1 influenza virus is associated with dysregulation of inflammation and lipoxin signaling in a mouse model of infection. J Virol (2010) 1.40
A member of a conserved Plasmodium protein family with membrane-attack complex/perforin (MACPF)-like domains localizes to the micronemes of sporozoites. Mol Biochem Parasitol (2004) 1.38
Hepatocyte growth factor and its receptor are required for malaria infection. Nat Med (2003) 1.37
The relevance of non-human primate and rodent malaria models for humans. Malar J (2011) 1.36
Neuroimmunological blood brain barrier opening in experimental cerebral malaria. PLoS Pathog (2012) 1.35
Liver-stage malaria parasites vulnerable to diverse chemical scaffolds. Proc Natl Acad Sci U S A (2012) 1.31
Malaria parasite pre-erythrocytic stage infection: gliding and hiding. Cell Host Microbe (2008) 1.30
Protective role of the inflammatory CCR2/CCL2 chemokine pathway through recruitment of type 1 cytotoxic γδ T lymphocytes to tumor beds. J Immunol (2013) 1.29
HGF/MET signalling protects Plasmodium-infected host cells from apoptosis. Cell Microbiol (2005) 1.28
VEGF promotes malaria-associated acute lung injury in mice. PLoS Pathog (2010) 1.28
Transformation of sporozoites into early exoerythrocytic malaria parasites does not require host cells. J Exp Med (2003) 1.26
Genetically attenuated P36p-deficient Plasmodium berghei sporozoites confer long-lasting and partial cross-species protection. Int J Parasitol (2007) 1.24
Plasmodium pyruvate dehydrogenase activity is only essential for the parasite's progression from liver infection to blood infection. Mol Microbiol (2010) 1.21
Kinome-wide RNAi screen implicates at least 5 host hepatocyte kinases in Plasmodium sporozoite infection. PLoS Pathog (2008) 1.20
PSLAP, a protein with multiple adhesive motifs, is expressed in Plasmodium falciparum gametocytes. Mol Biochem Parasitol (2002) 1.20
Total and putative surface proteomics of malaria parasite salivary gland sporozoites. Mol Cell Proteomics (2013) 1.19
Whole parasite vaccination approaches for prevention of malaria infection. Trends Immunol (2012) 1.18
Drug screen targeted at Plasmodium liver stages identifies a potent multistage antimalarial drug. J Infect Dis (2012) 1.18
Plasmodium berghei parasite transformed with green fluorescent protein for screening blood schizontocidal agents. Int J Parasitol (2004) 1.18
Distinct malaria parasite sporozoites reveal transcriptional changes that cause differential tissue infection competence in the mosquito vector and mammalian host. Mol Cell Biol (2008) 1.17
A toolbox to study liver stage malaria. Trends Parasitol (2011) 1.16
Adenylyl cyclase alpha and cAMP signaling mediate Plasmodium sporozoite apical regulated exocytosis and hepatocyte infection. PLoS Pathog (2008) 1.16
First-in-human evaluation of genetically attenuated Plasmodium falciparum sporozoites administered by bite of Anopheles mosquitoes to adult volunteers. Vaccine (2013) 1.16
Improved transfection and new selectable markers for the rodent malaria parasite Plasmodium yoelii. Mol Biochem Parasitol (2006) 1.14
The non-human primate reference transcriptome resource (NHPRTR) for comparative functional genomics. Nucleic Acids Res (2012) 1.13
Histone methyltransferase SETD2 coordinates FACT recruitment with nucleosome dynamics during transcription. Nucleic Acids Res (2013) 1.12
Quantitative bioluminescent imaging of pre-erythrocytic malaria parasite infection using luciferase-expressing Plasmodium yoelii. PLoS One (2013) 1.11
Interactions of the malaria parasite and its mammalian host. Curr Opin Microbiol (2008) 1.11
Cerebral malaria and the hemolysis/methemoglobin/heme hypothesis: shedding new light on an old disease. Int J Biochem Cell Biol (2008) 1.09
Suppression of host p53 is critical for Plasmodium liver-stage infection. Cell Rep (2013) 1.08
The alpha/beta interferon receptor provides protection against influenza virus replication but is dispensable for inflammatory response signaling. J Virol (2009) 1.07
Malaria vaccine development: persistent challenges. Curr Opin Immunol (2012) 1.07
Genetic engineering of attenuated malaria parasites for vaccination. Curr Opin Biotechnol (2012) 1.06
Transition of Plasmodium sporozoites into liver stage-like forms is regulated by the RNA binding protein Pumilio. PLoS Pathog (2011) 1.06
Malaria parasite pre-erythrocytic infection: preparation meets opportunity. Cell Microbiol (2012) 1.06
The IFN-γ-inducible GTPase, Irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens. PLoS One (2011) 1.06
Plasmodium falciparum MAEBL is a unique member of the ebl family. Mol Biochem Parasitol (2002) 1.06
Comparative genomics of the Rab protein family in Apicomplexan parasites. Microbes Infect (2008) 1.06
Cross-species immunity in malaria vaccine development: two, three, or even four for the price of one? Infect Immun (2007) 1.05
Torins are potent antimalarials that block replenishment of Plasmodium liver stage parasitophorous vacuole membrane proteins. Proc Natl Acad Sci U S A (2013) 1.05
SAP1 is a critical post-transcriptional regulator of infectivity in malaria parasite sporozoite stages. Mol Microbiol (2010) 1.04
Conserved protective mechanisms in radiation and genetically attenuated uis3(-) and uis4(-) Plasmodium sporozoites. PLoS One (2009) 1.04