Published in Curr Opin Biotechnol on May 04, 2012
Complete Plasmodium falciparum liver-stage development in liver-chimeric mice. J Clin Invest (2012) 1.52
Model for in vivo assessment of humoral protection against malaria sporozoite challenge by passive transfer of monoclonal antibodies and immune serum. Infect Immun (2013) 0.99
Type II fatty acid biosynthesis is essential for Plasmodium falciparum sporozoite development in the midgut of Anopheles mosquitoes. Eukaryot Cell (2013) 0.98
Mechanisms of stage-transcending protection following immunization of mice with late liver stage-arresting genetically attenuated malaria parasites. PLoS Pathog (2015) 0.90
A next-generation genetically attenuated Plasmodium falciparum parasite created by triple gene deletion. Mol Ther (2014) 0.89
A genetically attenuated malaria vaccine candidate based on P. falciparum b9/slarp gene-deficient sporozoites. Elife (2014) 0.89
A key role for lipoic acid synthesis during Plasmodium liver stage development. Cell Microbiol (2013) 0.87
Enzymes involved in plastid-targeted phosphatidic acid synthesis are essential for Plasmodium yoelii liver-stage development. Mol Microbiol (2014) 0.86
Plasmodium cellular effector mechanisms and the hepatic microenvironment. Front Microbiol (2015) 0.84
Of men in mice: the success and promise of humanized mouse models for human malaria parasite infections. Cell Microbiol (2014) 0.84
Zinc finger nuclease-based double-strand breaks attenuate malaria parasites and reveal rare microhomology-mediated end joining. Genome Biol (2015) 0.84
Discovery of Novel Plasmodium falciparum Pre-Erythrocytic Antigens for Vaccine Development. PLoS One (2015) 0.82
Multidrug ATP-binding cassette transporters are essential for hepatic development of Plasmodium sporozoites. Cell Microbiol (2015) 0.81
Imaging Plasmodium immunobiology in the liver, brain, and lung. Parasitol Int (2013) 0.81
Rapid Generation of Marker-Free P. falciparum Fluorescent Reporter Lines Using Modified CRISPR/Cas9 Constructs and Selection Protocol. PLoS One (2016) 0.78
Transfection of Babesia bovis by Double Selection with WR99210 and Blasticidin-S and Its Application for Functional Analysis of Thioredoxin Peroxidase-1. PLoS One (2015) 0.77
A Plasmodium yoelii Mei2-Like RNA Binding Protein Is Essential for Completion of Liver Stage Schizogony. Infect Immun (2016) 0.76
Molecular Markers of Radiation Induced Attenuation in Intrahepatic Plasmodium falciparum Parasites. PLoS One (2016) 0.75
Protective Efficacy Induced by Genetically Attenuated Mid-to-Late Liver-Stage Arresting Plasmodium berghei Δmrp2 Parasites. Am J Trop Med Hyg (2016) 0.75
Protective efficacy and safety of liver stage attenuated malaria parasites. Sci Rep (2016) 0.75
Enhancing protective immunity to malaria with a highly immunogenic virus-like particle vaccine. Sci Rep (2017) 0.75
Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii yoelii. Nature (2002) 8.92
Malaria: progress, perils, and prospects for eradication. J Clin Invest (2008) 6.54
A comprehensive survey of the Plasmodium life cycle by genomic, transcriptomic, and proteomic analyses. Science (2005) 5.99
A Plasmodium berghei reference line that constitutively expresses GFP at a high level throughout the complete life cycle. Mol Biochem Parasitol (2004) 5.80
Complement-like protein TEP1 is a determinant of vectorial capacity in the malaria vector Anopheles gambiae. Cell (2004) 5.24
Genetically modified Plasmodium parasites as a protective experimental malaria vaccine. Nature (2004) 4.35
Regulation of sexual development of Plasmodium by translational repression. Science (2006) 4.15
Proteome analysis of separated male and female gametocytes reveals novel sex-specific Plasmodium biology. Cell (2005) 3.77
A combined transcriptome and proteome survey of malaria parasite liver stages. Proc Natl Acad Sci U S A (2008) 3.56
Plasmodium liver stage developmental arrest by depletion of a protein at the parasite-host interface. Proc Natl Acad Sci U S A (2005) 3.06
The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites. Cell Host Microbe (2008) 2.98
Murine malaria parasite sequestration: CD36 is the major receptor, but cerebral pathology is unlinked to sequestration. Proc Natl Acad Sci U S A (2005) 2.71
Genetically attenuated, P36p-deficient malarial sporozoites induce protective immunity and apoptosis of infected liver cells. Proc Natl Acad Sci U S A (2005) 2.49
Type II fatty acid synthesis is essential only for malaria parasite late liver stage development. Cell Microbiol (2008) 2.49
Visualisation and quantitative analysis of the rodent malaria liver stage by real time imaging. PLoS One (2009) 2.18
Identification of a transcription factor in the mosquito-invasive stage of malaria parasites. Mol Microbiol (2009) 2.10
A Plasmodium whole-genome synteny map: indels and synteny breakpoints as foci for species-specific genes. PLoS Pathog (2005) 2.05
Protracted sterile protection with Plasmodium yoelii pre-erythrocytic genetically attenuated parasite malaria vaccines is independent of significant liver-stage persistence and is mediated by CD8+ T cells. J Infect Dis (2007) 1.99
Proteomic profiling of Plasmodium sporozoite maturation identifies new proteins essential for parasite development and infectivity. PLoS Pathog (2008) 1.98
Universal features of post-transcriptional gene regulation are critical for Plasmodium zygote development. PLoS Pathog (2010) 1.90
Real-time, in vivo analysis of malaria ookinete locomotion and mosquito midgut invasion. Cell Microbiol (2004) 1.85
Myosin A tail domain interacting protein (MTIP) localizes to the inner membrane complex of Plasmodium sporozoites. J Cell Sci (2003) 1.85
Infectivity-associated changes in the transcriptional repertoire of the malaria parasite sporozoite stage. J Biol Chem (2002) 1.83
Quantitative isolation and in vivo imaging of malaria parasite liver stages. Int J Parasitol (2006) 1.83
Plasmodium yoelii sporozoites with simultaneous deletion of P52 and P36 are completely attenuated and confer sterile immunity against infection. Infect Immun (2007) 1.79
Genetically attenuated Plasmodium berghei liver stages induce sterile protracted protection that is mediated by major histocompatibility complex Class I-dependent interferon-gamma-producing CD8+ T cells. J Infect Dis (2007) 1.79
Differential transcriptome profiling identifies Plasmodium genes encoding pre-erythrocytic stage-specific proteins. Mol Microbiol (2004) 1.76
Three members of the 6-cys protein family of Plasmodium play a role in gamete fertility. PLoS Pathog (2010) 1.72
Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design. Proc Natl Acad Sci U S A (2009) 1.72
Molecular genetics and comparative genomics reveal RNAi is not functional in malaria parasites. Nucleic Acids Res (2009) 1.71
A specific inhibitor of PfCDPK4 blocks malaria transmission: chemical-genetic validation. J Infect Dis (2013) 1.71
Release of hepatic Plasmodium yoelii merozoites into the pulmonary microvasculature. PLoS Pathog (2007) 1.67
A role for natural regulatory T cells in the pathogenesis of experimental cerebral malaria. Am J Pathol (2007) 1.67
The malaria secretome: from algorithms to essential function in blood stage infection. PLoS Pathog (2008) 1.67
Functional identification of the Plasmodium centromere and generation of a Plasmodium artificial chromosome. Cell Host Microbe (2010) 1.63
Heme oxygenase-1 is an anti-inflammatory host factor that promotes murine plasmodium liver infection. Cell Host Microbe (2008) 1.62
Superior antimalarial immunity after vaccination with late liver stage-arresting genetically attenuated parasites. Cell Host Microbe (2011) 1.61
Targeted deletion of SAP1 abolishes the expression of infectivity factors necessary for successful malaria parasite liver infection. Mol Microbiol (2008) 1.56
Real-time quantitative reverse transcription PCR for monitoring of blood-stage Plasmodium falciparum infections in malaria human challenge trials. Am J Trop Med Hyg (2012) 1.55
Complete Plasmodium falciparum liver-stage development in liver-chimeric mice. J Clin Invest (2012) 1.52
Host cell transcriptional profiling during malaria liver stage infection reveals a coordinated and sequential set of biological events. BMC Genomics (2009) 1.52
Malaria parasite development in the mosquito and infection of the mammalian host. Annu Rev Microbiol (2009) 1.52
Genetically engineered, attenuated whole-cell vaccine approaches for malaria. Hum Vaccin (2010) 1.50
L-FABP is a critical host factor for successful malaria liver stage development. Int J Parasitol (2007) 1.48
A cyclic GMP signalling module that regulates gliding motility in a malaria parasite. PLoS Pathog (2009) 1.46
Novel inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with anti-malarial activity in the mouse model. J Biol Chem (2010) 1.46
Pfs47, paralog of the male fertility factor Pfs48/45, is a female specific surface protein in Plasmodium falciparum. Mol Biochem Parasitol (2006) 1.42
A member of a conserved Plasmodium protein family with membrane-attack complex/perforin (MACPF)-like domains localizes to the micronemes of sporozoites. Mol Biochem Parasitol (2004) 1.38
Development and application of a positive-negative selectable marker system for use in reverse genetics in Plasmodium. Nucleic Acids Res (2006) 1.36
Neuroimmunological blood brain barrier opening in experimental cerebral malaria. PLoS Pathog (2012) 1.35
Real-time in vivo imaging of transgenic bioluminescent blood stages of rodent malaria parasites in mice. Nat Protoc (2006) 1.31
A comprehensive evaluation of rodent malaria parasite genomes and gene expression. BMC Biol (2014) 1.31
Malaria parasite pre-erythrocytic stage infection: gliding and hiding. Cell Host Microbe (2008) 1.30
The glutathione biosynthetic pathway of Plasmodium is essential for mosquito transmission. PLoS Pathog (2009) 1.28
Development of the malaria parasite in the skin of the mammalian host. Proc Natl Acad Sci U S A (2010) 1.27
Egress of Plasmodium berghei gametes from their host erythrocyte is mediated by the MDV-1/PEG3 protein. Cell Microbiol (2009) 1.26
Transformation of sporozoites into early exoerythrocytic malaria parasites does not require host cells. J Exp Med (2003) 1.26
Plasmepsin 4-deficient Plasmodium berghei are virulence attenuated and induce protective immunity against experimental malaria. Am J Pathol (2009) 1.26
Gene disruption of Plasmodium falciparum p52 results in attenuation of malaria liver stage development in cultured primary human hepatocytes. PLoS One (2008) 1.25
Genetically attenuated P36p-deficient Plasmodium berghei sporozoites confer long-lasting and partial cross-species protection. Int J Parasitol (2007) 1.24
Functional characterization of the Plasmodium falciparum and P. berghei homologues of macrophage migration inhibitory factor. Infect Immun (2006) 1.23
Sequestration and tissue accumulation of human malaria parasites: can we learn anything from rodent models of malaria? PLoS Pathog (2010) 1.23
A conserved U-rich RNA region implicated in regulation of translation in Plasmodium female gametocytes. Nucleic Acids Res (2007) 1.23
A novel 'gene insertion/marker out' (GIMO) method for transgene expression and gene complementation in rodent malaria parasites. PLoS One (2011) 1.22
Plasmodium pyruvate dehydrogenase activity is only essential for the parasite's progression from liver infection to blood infection. Mol Microbiol (2010) 1.21
Reduced CD36-dependent tissue sequestration of Plasmodium-infected erythrocytes is detrimental to malaria parasite growth in vivo. J Exp Med (2011) 1.20
Plasmodium post-genomics: better the bug you know? Nat Rev Microbiol (2006) 1.20
Total and putative surface proteomics of malaria parasite salivary gland sporozoites. Mol Cell Proteomics (2013) 1.19
Whole parasite vaccination approaches for prevention of malaria infection. Trends Immunol (2012) 1.18
Distinct malaria parasite sporozoites reveal transcriptional changes that cause differential tissue infection competence in the mosquito vector and mammalian host. Mol Cell Biol (2008) 1.17
The Plasmodium TRAP/MIC2 family member, TRAP-Like Protein (TLP), is involved in tissue traversal by sporozoites. Cell Microbiol (2008) 1.17
First-in-human evaluation of genetically attenuated Plasmodium falciparum sporozoites administered by bite of Anopheles mosquitoes to adult volunteers. Vaccine (2013) 1.16
The use of transgenic Plasmodium berghei expressing the Plasmodium vivax antigen P25 to determine the transmission-blocking activity of sera from malaria vaccine trials. Vaccine (2006) 1.12
Assessing the adequacy of attenuation of genetically modified malaria parasite vaccine candidates. Vaccine (2012) 1.11
Quantitative bioluminescent imaging of pre-erythrocytic malaria parasite infection using luciferase-expressing Plasmodium yoelii. PLoS One (2013) 1.11
PTRAMP; a conserved Plasmodium thrombospondin-related apical merozoite protein. Mol Biochem Parasitol (2004) 1.10
Going live: a comparative analysis of the suitability of the RFP derivatives RedStar, mCherry and tdTomato for intravital and in vitro live imaging of Plasmodium parasites. Biotechnol J (2009) 1.09
Suppression of host p53 is critical for Plasmodium liver-stage infection. Cell Rep (2013) 1.08
Malaria vaccine development: persistent challenges. Curr Opin Immunol (2012) 1.07
Genome-wide RIP-Chip analysis of translational repressor-bound mRNAs in the Plasmodium gametocyte. Genome Biol (2014) 1.07
Analysis of mutant Plasmodium berghei parasites lacking expression of multiple PbCCp genes. Mol Biochem Parasitol (2008) 1.06
Malaria parasite pre-erythrocytic infection: preparation meets opportunity. Cell Microbiol (2012) 1.06
Plasmodium falciparum MAEBL is a unique member of the ebl family. Mol Biochem Parasitol (2002) 1.06
Hemozoin induces lung inflammation and correlates with malaria-associated acute respiratory distress syndrome. Am J Respir Cell Mol Biol (2013) 1.06
Plasmodium liver load following parenteral sporozoite administration in rodents. Vaccine (2012) 1.04
Two Plasmodium 6-Cys family-related proteins have distinct and critical roles in liver-stage development. FASEB J (2014) 1.04
Conserved protective mechanisms in radiation and genetically attenuated uis3(-) and uis4(-) Plasmodium sporozoites. PLoS One (2009) 1.04
SAP1 is a critical post-transcriptional regulator of infectivity in malaria parasite sporozoite stages. Mol Microbiol (2010) 1.04
Proteomic and genetic analyses demonstrate that Plasmodium berghei blood stages export a large and diverse repertoire of proteins. Mol Cell Proteomics (2012) 1.03
Preerythrocytic malaria vaccine development. Curr Opin Infect Dis (2007) 1.03
Plasmodium cysteine repeat modular proteins 1-4: complex proteins with roles throughout the malaria parasite life cycle. Cell Microbiol (2007) 1.01
Plasmodium lipid rafts contain proteins implicated in vesicular trafficking and signalling as well as members of the PIR superfamily, potentially implicated in host immune system interactions. Proteomics (2008) 1.01