Published in Int J Biochem Cell Biol on June 17, 2009
The RIP140 gene is a transcriptional target of E2F1. PLoS One (2012) 0.89
E2F1 mediated apoptosis induced by the DNA damage response is blocked by EBV nuclear antigen 3C in lymphoblastoid cells. PLoS Pathog (2012) 0.89
Expressions and clinical significances of c-MET, p-MET and E2f-1 in human gastric carcinoma. BMC Res Notes (2014) 0.86
Repression of androgen receptor transcription through the E2F1/DNMT1 axis. PLoS One (2011) 0.86
Heme oxygenase-1 regulates postnatal lung repair after hyperoxia: role of β-catenin/hnRNPK signaling. Redox Biol (2013) 0.84
Intestine-specific homeobox (ISX) upregulates E2F1 expression and related oncogenic activities in HCC. Oncotarget (2016) 0.82
E2F1: a potential negative regulator of hTERT transcription in normal cells upon activation of oncogenic c-Myc. Med Sci Monit (2012) 0.79
Modulation of cellular stress response via the erythropoietin/CD131 heteroreceptor complex in mouse mesenchymal-derived cells. J Mol Med (Berl) (2014) 0.78
The E2F1 oncogene transcriptionally regulates NELL2 in cancer cells. DNA Cell Biol (2013) 0.78
Deregulation of Rb-E2F1 axis causes chromosomal instability by engaging the transactivation function of Cdc20-anaphase-promoting complex/cyclosome. Mol Cell Biol (2014) 0.78
Genomic and genetic variation in E2F transcription factor-1 in men with nonobstructive azoospermia. Fertil Steril (2014) 0.78
E2F transcription factor 1 regulates cellular and organismal senescence by inhibiting Forkhead box O transcription factors. J Biol Chem (2014) 0.77
The Prognostic Role and Relationship between E2F1 and SV40 in Diffuse Large B-Cell Lymphoma of Egyptian Patients. Anal Cell Pathol (Amst) (2015) 0.77
Hypoxia promotes cell proliferation by modulating E2F1 in chicken pulmonary arterial smooth muscle cells. J Anim Sci Biotechnol (2013) 0.77
E2F-1 overexpression inhibits human gastric cancer MGC-803 cell growth in vivo. World J Gastroenterol (2015) 0.76
E2F1 Transcription Factor Regulates O-linked N-acetylglucosamine (O-GlcNAc) Transferase and O-GlcNAcase Expression. J Biol Chem (2015) 0.75
A global map of p53 transcription-factor binding sites in the human genome. Cell (2006) 20.65
Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells. Genes Dev (2007) 6.71
Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis. Cell (2012) 3.92
DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications. Cancer Cell (2008) 2.46
B55β-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer. Cancer Cell (2010) 2.44
Impact of agricultural management practices on soil organic carbon: simulation of Australian wheat systems. Glob Chang Biol (2013) 2.37
Derepression of ethylene-stabilized transcription factors (EIN3/EIL1) mediates jasmonate and ethylene signaling synergy in Arabidopsis. Proc Natl Acad Sci U S A (2011) 2.25
Context-specific regulation of NF-κB target gene expression by EZH2 in breast cancers. Mol Cell (2011) 2.12
Inhibitors of histone deacetylases target the Rb-E2F1 pathway for apoptosis induction through activation of proapoptotic protein Bim. Proc Natl Acad Sci U S A (2005) 2.07
miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A. Genes Dev (2009) 1.91
Environment. Building a "green" railway in China. Science (2007) 1.73
p53-regulated transcriptional program associated with genotoxic stress-induced apoptosis. J Biol Chem (2004) 1.70
Endoplasmic reticulum stress is implicated in retinal inflammation and diabetic retinopathy. FEBS Lett (2009) 1.65
FOXQ1 regulates epithelial-mesenchymal transition in human cancers. Cancer Res (2011) 1.55
CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells. PLoS One (2009) 1.52
[Effects of different statin regimens on lipid profile and serum metalloproteinases in patients with coronary heart disease]. Zhonghua Xin Xue Guan Bing Za Zhi (2009) 1.50
Mitochondrial electron transport chain complex III is required for antimycin A to inhibit autophagy. Chem Biol (2011) 1.50
The histone methyltransferase inhibitor, DZNep, up-regulates TXNIP, increases ROS production, and targets leukemia cells in AML. Blood (2011) 1.49
Association between bone mineral density and type 2 diabetes mellitus: a meta-analysis of observational studies. Eur J Epidemiol (2012) 1.46
BRCA1-deficient mammary tumor cells are dependent on EZH2 expression and sensitive to Polycomb Repressive Complex 2-inhibitor 3-deazaneplanocin A. Breast Cancer Res (2009) 1.44
Arginine methylation controls growth regulation by E2F-1. EMBO J (2012) 1.44
Pharmacologic modulation of glycogen synthase kinase-3beta promotes p53-dependent apoptosis through a direct Bax-mediated mitochondrial pathway in colorectal cancer cells. Cancer Res (2005) 1.38
TXNIP (VDUP-1, TBP-2): a major redox regulator commonly suppressed in cancer by epigenetic mechanisms. Int J Biochem Cell Biol (2011) 1.26
Heparan sulfate-FGF10 interactions during lung morphogenesis. Dev Biol (2003) 1.24
Nitrogen deposition weakens plant-microbe interactions in grassland ecosystems. Glob Chang Biol (2013) 1.23
Systemic administration of HMG-CoA reductase inhibitor protects the blood-retinal barrier and ameliorates retinal inflammation in type 2 diabetes. Exp Eye Res (2009) 1.23
Activation of necroptosis in multiple sclerosis. Cell Rep (2015) 1.21
Altered regulation of Src upon cell detachment protects human lung adenocarcinoma cells from anoikis. Oncogene (2004) 1.20
Arginine methylation-dependent reader-writer interplay governs growth control by E2F-1. Mol Cell (2013) 1.12
Apoptosis signal-regulating kinase 1 is a direct target of E2F1 and contributes to histone deacetylase inhibitor-induced apoptosis through positive feedback regulation of E2F1 apoptotic activity. J Biol Chem (2006) 1.12
Sampling date, leaf age and root size: implications for the study of plant C:N:p stoichiometry. PLoS One (2013) 1.09
PDK1 signaling toward PLK1-MYC activation confers oncogenic transformation, tumor-initiating cell activation, and resistance to mTOR-targeted therapy. Cancer Discov (2013) 1.09
Ribosomal protein S27-like, a p53-inducible modulator of cell fate in response to genotoxic stress. Cancer Res (2007) 1.09
Convergent responses of nitrogen and phosphorus resorption to nitrogen inputs in a semiarid grassland. Glob Chang Biol (2013) 1.09
Cyclodepsipeptide toxin promotes the degradation of Hsp90 client proteins through chaperone-mediated autophagy. J Cell Biol (2009) 1.09
Differentially expressed gene profiles between multidrug resistant gastric adenocarcinoma cells and their parental cells. Cancer Lett (2002) 1.08
Production of a novel bioflocculant by Bacillus licheniformis X14 and its application to low temperature drinking water treatment. Bioresour Technol (2009) 1.08
Artificial neural network-genetic algorithm based optimization for the immobilization of cellulase on the smart polymer Eudragit L-100. Bioresour Technol (2010) 1.07
Impact of p53 knockout and topotecan treatment on gene expression profiles in human colon carcinoma cells: a pharmacogenomic study. Cancer Res (2003) 1.07
Bcl-2, via its BH4 domain, blocks apoptotic signaling mediated by mitochondrial Ras. J Biol Chem (2002) 1.05
An insertion/deletion polymorphism within RERT-lncRNA modulates hepatocellular carcinoma risk. Cancer Res (2012) 1.05
IGF-1 induces Pin1 expression in promoting cell cycle S-phase entry. J Cell Biochem (2002) 1.02
Triptolide (TPL) inhibits global transcription by inducing proteasome-dependent degradation of RNA polymerase II (Pol II). PLoS One (2011) 1.02
X-box binding protein 1 is essential for the anti-oxidant defense and cell survival in the retinal pigment epithelium. PLoS One (2012) 1.00
Characterization of microRNA expression profiles in patients with intervertebral disc degeneration. Int J Mol Med (2013) 1.00
Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells. Mol Cancer Ther (2009) 0.98
17-hydroxy-jolkinolide B inhibits signal transducers and activators of transcription 3 signaling by covalently cross-linking Janus kinases and induces apoptosis of human cancer cells. Cancer Res (2009) 0.98
Nitrogen addition regulates soil nematode community composition through ammonium suppression. PLoS One (2012) 0.97
A p53-independent G1 cell cycle checkpoint induced by the suppression of protein kinase C alpha and theta isoforms. J Biol Chem (2003) 0.97
Heparan sulfates expressed in the distal lung are required for Fgf10 binding to the epithelium and for airway branching. Am J Physiol Lung Cell Mol Physiol (2003) 0.95
TP53 genomic status regulates sensitivity of gastric cancer cells to the histone methylation inhibitor 3-deazaneplanocin A (DZNep). Clin Cancer Res (2012) 0.95
Expression of inwardly rectifying potassium channels (GIRKs) and beta-adrenergic regulation of breast cancer cell lines. BMC Cancer (2004) 0.95
Heterogeneous epigenetic regulation of TIMP3 in prostate cancer. Epigenetics (2012) 0.94
EZH2 overexpression in natural killer/T-cell lymphoma confers growth advantage independently of histone methyltransferase activity. Blood (2013) 0.94
Cleavage of p130Cas in anoikis. J Cell Biochem (2004) 0.94
Comparison of a rapid diagnostic test and microimmunofluorescence assay for detecting antibody to Orientia tsutsugamushi in scrub typhus patients in China. Asian Pac J Trop Med (2011) 0.93
Abietane diterpenoids from Clerodendrum bungei. J Nat Prod (2008) 0.93
Anchorage-independent phosphorylation of p130(Cas) protects lung adenocarcinoma cells from anoikis. J Cell Biochem (2002) 0.93
Dual regulation of Cdc25A by Chk1 and p53-ATF3 in DNA replication checkpoint control. J Biol Chem (2008) 0.93
A miR-1231 binding site polymorphism in the 3'UTR of IFNAR1 is associated with hepatocellular carcinoma susceptibility. Gene (2012) 0.93
Pigmented villonodular synovitis of the temporomandibular joint: CT imaging findings. Clin Imaging (2013) 0.93
A crucial role for bone morphogenetic protein-Smad1 signalling in the DNA damage response. Nat Commun (2012) 0.92
Sodium 4-phenylbutyrate induces apoptosis of human lung carcinoma cells through activating JNK pathway. J Cell Biochem (2004) 0.91
miR-449 regulates CDK-Rb-E2F1 through an auto-regulatory feedback circuit. Cell Cycle (2010) 0.91
Topotecan is a substrate for multidrug resistance associated protein 4. Curr Drug Metab (2006) 0.90
Molecular mechanisms of tumor resistance to PI3K-mTOR-targeted therapy. Chin J Cancer (2013) 0.90
Role of unfolded protein response dysregulation in oxidative injury of retinal pigment epithelial cells. Antioxid Redox Signal (2013) 0.90
RASAL2 activates RAC1 to promote triple-negative breast cancer progression. J Clin Invest (2014) 0.90
Protein tyrosine phosphatase UBASH3B is overexpressed in triple-negative breast cancer and promotes invasion and metastasis. Proc Natl Acad Sci U S A (2013) 0.90
Distinctive regulation and function of PI 3K/Akt and MAPKs in doxorubicin-induced apoptosis of human lung adenocarcinoma cells. J Cell Biochem (2004) 0.90
[Applicability of agricultural production systems simulator (APSIM) in simulating the production and water use of wheat-maize continuous cropping system in North China Plain]. Ying Yong Sheng Tai Xue Bao (2007) 0.89
Enhancement of carbon sequestration in soil in the temperature grasslands of northern China by addition of nitrogen and phosphorus. PLoS One (2013) 0.89
A 40-bp insertion/deletion polymorphism in the constitutive promoter of MDM2 confers risk for hepatocellular carcinoma in a Chinese population. Gene (2012) 0.88
Enhanced adsorption of arsenate on the aminated fibers: sorption behavior and uptake mechanism. Langmuir (2008) 0.88
c-Myc overexpression sensitizes Bim-mediated Bax activation for apoptosis induced by histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) through regulating Bcl-2/Bcl-xL expression. Int J Biochem Cell Biol (2007) 0.88
Evodiamine inhibits STAT3 signaling by inducing phosphatase shatterproof 1 in hepatocellular carcinoma cells. Cancer Lett (2012) 0.88
Neuronal-driven angiogenesis: role of NGF in retinal neovascularization in an oxygen-induced retinopathy model. Invest Ophthalmol Vis Sci (2010) 0.88
Rapid plant species loss at high rates and at low frequency of N addition in temperate steppe. Glob Chang Biol (2014) 0.88
Arctigenin preferentially induces tumor cell death under glucose deprivation by inhibiting cellular energy metabolism. Biochem Pharmacol (2012) 0.87
Stoichiometric homeostasis predicts plant species dominance, temporal stability, and responses to global change. Ecology (2015) 0.87
Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells. PLoS One (2011) 0.87
Insertion/deletion polymorphisms in the promoter region of BRM contribute to risk of hepatocellular carcinoma in Chinese populations. PLoS One (2013) 0.86
Ultrasonographic evaluation of mandibular ameloblastoma: a preliminary observation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2009) 0.86
A novel soil manganese mechanism drives plant species loss with increased nitrogen deposition in a temperate steppe. Ecology (2016) 0.86
17-Acetoxyjolkinolide B irreversibly inhibits IkappaB kinase and induces apoptosis of tumor cells. Mol Cancer Ther (2008) 0.85
Evaluation of solid lesions affecting masticator space with diffusion-weighted MR imaging. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2010) 0.85
Saturated fatty acids modulate cell response to DNA damage: implication for their role in tumorigenesis. PLoS One (2008) 0.85
Arctigenin alleviates ER stress via activating AMPK. Acta Pharmacol Sin (2012) 0.84
Effects of different pretreatment methods on chemical composition of sugarcane bagasse and enzymatic hydrolysis. Bioresour Technol (2013) 0.84
(-)-Epigallocatechin-3-gallate induces apoptosis of human hepatoma cells by mitochondrial pathways related to reactive oxygen species. J Agric Food Chem (2009) 0.83
Selective induction of tumor cell apoptosis by a novel P450-mediated reactive oxygen species (ROS) inducer methyl 3-(4-nitrophenyl) propiolate. J Biol Chem (2013) 0.83
Loading 3-deazaneplanocin A into pegylated unilamellar liposomes by forming transient phenylboronic acid-drug complex and its pharmacokinetic features in Sprague-Dawley rats. Eur J Pharm Biopharm (2011) 0.83
In-situ stabilisation followed by ex-situ composting for treatment and disposal of heavy metals polluted sediments. J Environ Sci (China) (2009) 0.82
4'-Alkoxyl substitution enhancing the anti-mitotic effect of 5-(3',4',5'-substituted)anilino-4-hydroxy-8-nitroquinazolines as a novel class of anti-microtubule agents. Bioorg Med Chem Lett (2006) 0.82
MiR-136 targets E2F1 to reverse cisplatin chemosensitivity in glioma cells. J Neurooncol (2014) 0.82
Triterpenoids from Sanguisorba officinalis. Phytochemistry (2005) 0.82
Rapid feedforward computation by temporal encoding and learning with spiking neurons. IEEE Trans Neural Netw Learn Syst (2013) 0.82
Study of the PTEN gene expression and FAK phosphorylation in human hepatocarcinoma tissues and cell lines. Mol Cell Biochem (2004) 0.81
Distribution of stomatin expressing in the central nervous system and its up-regulation in cerebral cortex of rat by hypoxia. J Neurochem (2010) 0.81