Published in Cancer Res on December 01, 2007
Depletion of ribosomal protein L37 occurs in response to DNA damage and activates p53 through the L11/MDM2 pathway. Cell Cycle (2010) 2.41
Alemtuzumab treatment of intermediate-1 myelodysplasia patients is associated with sustained improvement in blood counts and cytogenetic remissions. J Clin Oncol (2010) 1.79
Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits. J Cell Biol (2010) 1.58
Glucose starvation boosts Entamoeba histolytica virulence. PLoS Negl Trop Dis (2011) 1.56
Ribosomal protein S27-like and S27 interplay with p53-MDM2 axis as a target, a substrate and a regulator. Oncogene (2010) 1.09
Polycomb protein EZH2 regulates cancer cell fate decision in response to DNA damage. Cell Death Differ (2011) 1.07
Dissection of a complex transcriptional response using genome-wide transcriptional modelling. Mol Syst Biol (2009) 1.01
Ribosomal proteins and human diseases: pathogenesis, molecular mechanisms, and therapeutic implications. Med Res Rev (2014) 0.98
p53 -Dependent and -Independent Nucleolar Stress Responses. Cells (2012) 0.95
Serine/threonine kinase 17A is a novel p53 target gene and modulator of cisplatin toxicity and reactive oxygen species in testicular cancer cells. J Biol Chem (2011) 0.90
The Many Faces of MDM2 Binding Partners. Genes Cancer (2012) 0.90
A predicted protein, KIAA0247, is a cell cycle modulator in colorectal cancer cells under 5-FU treatment. J Transl Med (2011) 0.84
Proposed megakaryocytic regulon of p53: the genes engaged to control cell cycle and apoptosis during megakaryocytic differentiation. Physiol Genomics (2012) 0.82
Identification of a large protein network involved in epigenetic transmission in replicating DNA of embryonic stem cells. Nucleic Acids Res (2014) 0.81
Lowly expressed ribosomal protein s19 in the feces of patients with colorectal cancer. ISRN Gastroenterol (2012) 0.80
Ribosomal protein S27-like in colorectal cancer: a candidate for predicting prognoses. PLoS One (2013) 0.80
Important genes in the pathogenesis of 5q- syndrome and their connection with ribosomal stress and the innate immune system pathway. Leuk Res Treatment (2012) 0.79
Ribosomal protein S27-like is a physiological regulator of p53 that suppresses genomic instability and tumorigenesis. Elife (2014) 0.77
Epigenetic bystander-like effects of stroke in somatic organs. Aging (Albany NY) (2012) 0.76
Nucleocytoplasmic Translocation of UBXN2A Is Required for Apoptosis during DNA Damage Stresses in Colon Cancer Cells. J Cancer (2015) 0.76
A global map of p53 transcription-factor binding sites in the human genome. Cell (2006) 20.65
Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells. Genes Dev (2007) 6.71
Cytotoxicity and genotoxicity of silver nanoparticles in human cells. ACS Nano (2009) 5.22
Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis. Cell (2012) 3.92
Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells. Nature (2010) 3.54
TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator. Immunity (2002) 3.46
Crystal structure of the specificity domain of ribonuclease P. Nature (2003) 2.69
DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications. Cancer Cell (2008) 2.46
DNA methylation screening identifies driver epigenetic events of cancer cell survival. Cancer Cell (2012) 2.45
B55β-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer. Cancer Cell (2010) 2.44
Impact of agricultural management practices on soil organic carbon: simulation of Australian wheat systems. Glob Chang Biol (2013) 2.37
Derepression of ethylene-stabilized transcription factors (EIN3/EIL1) mediates jasmonate and ethylene signaling synergy in Arabidopsis. Proc Natl Acad Sci U S A (2011) 2.25
Context-specific regulation of NF-κB target gene expression by EZH2 in breast cancers. Mol Cell (2011) 2.12
Inhibitors of histone deacetylases target the Rb-E2F1 pathway for apoptosis induction through activation of proapoptotic protein Bim. Proc Natl Acad Sci U S A (2005) 2.07
Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome. Nat Genet (2012) 2.02
Structure and function of plant photoreceptors. Annu Rev Plant Biol (2010) 1.93
Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBM. Proc Natl Acad Sci U S A (2010) 1.91
miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A. Genes Dev (2009) 1.91
Common variants on 8p12 and 1q24.2 confer risk of schizophrenia. Nat Genet (2011) 1.88
Specific role of Chk1 phosphorylations in cell survival and checkpoint activation. Mol Cell Biol (2007) 1.87
p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling. J Cell Biol (2005) 1.86
DNA methylation directly silences genes with non-CpG island promoters and establishes a nucleosome occupied promoter. Hum Mol Genet (2011) 1.83
Environment. Building a "green" railway in China. Science (2007) 1.73
Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions. EMBO J (2012) 1.71
Electronic nicotine delivery systems: regulatory and safety challenges: Singapore perspective. Tob Control (2012) 1.70
p53-regulated transcriptional program associated with genotoxic stress-induced apoptosis. J Biol Chem (2004) 1.70
Automated crystallographic system for high-throughput protein structure determination. Acta Crystallogr D Biol Crystallogr (2003) 1.67
Endoplasmic reticulum stress is implicated in retinal inflammation and diabetic retinopathy. FEBS Lett (2009) 1.65
FoxOs enforce a progression checkpoint to constrain mTORC1-activated renal tumorigenesis. Cancer Cell (2010) 1.58
FOXQ1 regulates epithelial-mesenchymal transition in human cancers. Cancer Res (2011) 1.55
Deletion of DDB1 in mouse brain and lens leads to p53-dependent elimination of proliferating cells. Cell (2006) 1.54
Connective tissue growth factor is overexpressed in esophageal squamous cell carcinoma and promotes tumorigenicity through beta-catenin-T-cell factor/Lef signaling. J Biol Chem (2007) 1.53
CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells. PLoS One (2009) 1.52
Structural basis for an unexpected mode of SERM-mediated ER antagonism. Mol Cell (2005) 1.50
[Effects of different statin regimens on lipid profile and serum metalloproteinases in patients with coronary heart disease]. Zhonghua Xin Xue Guan Bing Za Zhi (2009) 1.50
Mitochondrial electron transport chain complex III is required for antimycin A to inhibit autophagy. Chem Biol (2011) 1.50
The histone methyltransferase inhibitor, DZNep, up-regulates TXNIP, increases ROS production, and targets leukemia cells in AML. Blood (2011) 1.49
Association between bone mineral density and type 2 diabetes mellitus: a meta-analysis of observational studies. Eur J Epidemiol (2012) 1.46
BRCA1-deficient mammary tumor cells are dependent on EZH2 expression and sensitive to Polycomb Repressive Complex 2-inhibitor 3-deazaneplanocin A. Breast Cancer Res (2009) 1.44
TL1A-induced NF-kappaB activation and c-IAP2 production prevent DR3-mediated apoptosis in TF-1 cells. J Biol Chem (2003) 1.40
Pharmacologic modulation of glycogen synthase kinase-3beta promotes p53-dependent apoptosis through a direct Bax-mediated mitochondrial pathway in colorectal cancer cells. Cancer Res (2005) 1.38
Identification of Sec36p, Sec37p, and Sec38p: components of yeast complex that contains Sec34p and Sec35p. Mol Biol Cell (2002) 1.37
TXNIP (VDUP-1, TBP-2): a major redox regulator commonly suppressed in cancer by epigenetic mechanisms. Int J Biochem Cell Biol (2011) 1.26
Activation of p38 mitogen-activated protein kinase is required for osteoblast differentiation. Endocrinology (2003) 1.25
Heparan sulfate-FGF10 interactions during lung morphogenesis. Dev Biol (2003) 1.24
Nitrogen deposition weakens plant-microbe interactions in grassland ecosystems. Glob Chang Biol (2013) 1.23
Systemic administration of HMG-CoA reductase inhibitor protects the blood-retinal barrier and ameliorates retinal inflammation in type 2 diabetes. Exp Eye Res (2009) 1.23
Activation of necroptosis in multiple sclerosis. Cell Rep (2015) 1.21
Altered regulation of Src upon cell detachment protects human lung adenocarcinoma cells from anoikis. Oncogene (2004) 1.20
S6K1 is a multifaceted regulator of Mdm2 that connects nutrient status and DNA damage response. EMBO J (2010) 1.18
Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML. Blood (2011) 1.17
The vertical distribution of bacterial and archaeal communities in the water and sediment of Lake Taihu. FEMS Microbiol Ecol (2009) 1.17
Automated real-space refinement of protein structures using a realistic backbone move set. Biophys J (2011) 1.16
Pyk2 activation is integral to acid stimulation of sodium/hydrogen exchanger 3. J Clin Invest (2004) 1.15
Arginine methylation-dependent reader-writer interplay governs growth control by E2F-1. Mol Cell (2013) 1.12
Apoptosis signal-regulating kinase 1 is a direct target of E2F1 and contributes to histone deacetylase inhibitor-induced apoptosis through positive feedback regulation of E2F1 apoptotic activity. J Biol Chem (2006) 1.12
Novel catalytic mechanism of glycoside hydrolysis based on the structure of an NAD+/Mn2+ -dependent phospho-alpha-glucosidase from Bacillus subtilis. Structure (2004) 1.11
ERK phosphorylates p66shcA on Ser36 and subsequently regulates p27kip1 expression via the Akt-FOXO3a pathway: implication of p27kip1 in cell response to oxidative stress. Mol Biol Cell (2005) 1.11
Sampling date, leaf age and root size: implications for the study of plant C:N:p stoichiometry. PLoS One (2013) 1.09
PDK1 signaling toward PLK1-MYC activation confers oncogenic transformation, tumor-initiating cell activation, and resistance to mTOR-targeted therapy. Cancer Discov (2013) 1.09
Convergent responses of nitrogen and phosphorus resorption to nitrogen inputs in a semiarid grassland. Glob Chang Biol (2013) 1.09
Cyclodepsipeptide toxin promotes the degradation of Hsp90 client proteins through chaperone-mediated autophagy. J Cell Biol (2009) 1.09
Functional DNA demethylation is accompanied by chromatin accessibility. Nucleic Acids Res (2013) 1.09
Differentially expressed gene profiles between multidrug resistant gastric adenocarcinoma cells and their parental cells. Cancer Lett (2002) 1.08
Production of a novel bioflocculant by Bacillus licheniformis X14 and its application to low temperature drinking water treatment. Bioresour Technol (2009) 1.08
Artificial neural network-genetic algorithm based optimization for the immobilization of cellulase on the smart polymer Eudragit L-100. Bioresour Technol (2010) 1.07
Impact of p53 knockout and topotecan treatment on gene expression profiles in human colon carcinoma cells: a pharmacogenomic study. Cancer Res (2003) 1.07
Synthesis and SAR of 1,2,3,4-tetrahydroisoquinolin-1-ones as novel G-protein-coupled receptor 40 (GPR40) antagonists. Bioorg Med Chem Lett (2009) 1.06
Somatic mutations of PIK3R1 promote gliomagenesis. PLoS One (2012) 1.06
Bcl-2, via its BH4 domain, blocks apoptotic signaling mediated by mitochondrial Ras. J Biol Chem (2002) 1.05
An insertion/deletion polymorphism within RERT-lncRNA modulates hepatocellular carcinoma risk. Cancer Res (2012) 1.05
Activation of Nrf2 and accumulation of ubiquitinated A170 by arsenic in osteoblasts. Biochem Biophys Res Commun (2003) 1.05
p38 mitogen-activated protein kinase regulates osteoblast differentiation through osterix. Endocrinology (2006) 1.04
Atm-deficient mice: an osteoporosis model with defective osteoblast differentiation and increased osteoclastogenesis. Hum Mol Genet (2006) 1.04
Bioengineered 'golden' indica rice cultivars with beta-carotene metabolism in the endosperm with hygromycin and mannose selection systems. Plant Biotechnol J (2003) 1.02
IGF-1 induces Pin1 expression in promoting cell cycle S-phase entry. J Cell Biochem (2002) 1.02
FoxO transcription factors promote AKT Ser473 phosphorylation and renal tumor growth in response to pharmacologic inhibition of the PI3K-AKT pathway. Cancer Res (2014) 1.02
The E2F family and the role of E2F1 in apoptosis. Int J Biochem Cell Biol (2009) 1.02
Triptolide (TPL) inhibits global transcription by inducing proteasome-dependent degradation of RNA polymerase II (Pol II). PLoS One (2011) 1.02
An unusual mechanism of glycoside hydrolysis involving redox and elimination steps by a family 4 beta-glycosidase from Thermotoga maritima. J Am Chem Soc (2004) 1.01
Cooperative functions of Chk1 and Chk2 reduce tumour susceptibility in vivo. EMBO J (2010) 1.00
X-box binding protein 1 is essential for the anti-oxidant defense and cell survival in the retinal pigment epithelium. PLoS One (2012) 1.00
Characterization of microRNA expression profiles in patients with intervertebral disc degeneration. Int J Mol Med (2013) 1.00
Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells. Mol Cancer Ther (2009) 0.98