Published in J Immunol on July 01, 2009
MicroRNA in TLR signaling and endotoxin tolerance. Cell Mol Immunol (2011) 1.86
Mechanistic role of microRNA-146a in endotoxin-induced differential cross-regulation of TLR signaling. J Immunol (2010) 1.58
Methicillin-resistant Staphylococcus aureus-induced thrombo-inflammatory response is reduced with timely antibiotic administration. Thromb Haemost (2013) 1.39
Epigenetic regulation of immune cell functions during post-septic immunosuppression. Epigenetics (2011) 1.38
Regulation of TLR2-mediated tolerance and cross-tolerance through IRAK4 modulation by miR-132 and miR-212. J Immunol (2012) 1.16
TGF-β-induced IRAK-M expression in tumor-associated macrophages regulates lung tumor growth. Oncogene (2011) 1.15
Toll-like receptor signaling: a potential link among rheumatoid arthritis, systemic lupus, and atherosclerosis. J Leukoc Biol (2010) 1.09
Elevation in body temperature to fever range enhances and prolongs subsequent responsiveness of macrophages to endotoxin challenge. PLoS One (2012) 1.06
Toll-like receptors and skin cancer. Front Immunol (2014) 0.90
Induction of Bcl-3 by acute binge alcohol results in toll-like receptor 4/LPS tolerance. J Leukoc Biol (2012) 0.89
TLR cross-talk confers specificity to innate immunity. Int Rev Immunol (2014) 0.86
Microvesicles at the crossroads between infection and cardiovascular diseases. J Cardiovasc Pharmacol (2012) 0.86
Endotoxin tolerance and cross-tolerance in mast cells involves TLR4, TLR2 and FcepsilonR1 interactions and SOCS expression: perspectives on immunomodulation in infectious and allergic diseases. BMC Infect Dis (2010) 0.85
Immune mediators of protective and pathogenic immune responses in patients with mild and fatal human monocytotropic ehrlichiosis. BMC Immunol (2012) 0.84
Chemokine-chemokine receptor CCL2-CCR2 and CX3CL1-CX3CR1 axis may play a role in the aggravated inflammation in primary biliary cirrhosis. Dig Dis Sci (2013) 0.83
Characterization of the inflammatory response to inhaled lipopolysaccharide in mild to moderate chronic obstructive pulmonary disease. Br J Clin Pharmacol (2015) 0.82
Epigenetic Regulation of Tolerance to Toll-Like Receptor Ligands in Alveolar Epithelial Cells. Am J Respir Cell Mol Biol (2015) 0.81
Leukocyte- and platelet-derived microvesicle interactions following in vitro and in vivo activation of toll-like receptor 4 by lipopolysaccharide. PLoS One (2011) 0.80
Role of TLR5 and flagella in bacillus intraocular infection. PLoS One (2014) 0.80
A20 is critical for the induction of Pam3CSK4-tolerance in monocytic THP-1 cells. PLoS One (2014) 0.79
The structure function of the death domain of human IRAK-M. Cell Commun Signal (2014) 0.78
Microbial cell components induced tolerance to flagellin-stimulated inflammation through Toll-like receptor pathways in intestinal epithelial cells. Cytokine (2012) 0.78
Innate immune reconstitution with suppression of HIV-1. JCI Insight (2016) 0.77
Fractal-like kinetics of intracellular enzymatic reactions: a chemical framework of endotoxin tolerance and a possible non-specific contribution of macromolecular crowding to cross-tolerance. Theor Biol Med Model (2013) 0.77
Antibiotic-Induced Gut Microbiota Disruption Decreases TNF-α Release by Mononuclear Cells in Healthy Adults. Clin Transl Gastroenterol (2016) 0.77
Novel Immunomodulatory Flagellin-Like Protein FlaC in Campylobacter jejuni and Other Campylobacterales. mSphere (2015) 0.76
Gamma-irradiated bacille Calmette-Guérin vaccination does not modulate the innate immune response during experimental human endotoxemia in adult males. J Immunol Res (2015) 0.76
Transvenous vagus nerve stimulation does not modulate the innate immune response during experimental human endotoxemia: a randomized controlled study. Arthritis Res Ther (2015) 0.76
Immune dysfunction in patients with obstructive jaundice before and after endoscopic retrograde cholangiopancreatography. Clin Sci (Lond) (2016) 0.75
TLR ligands, but not modulators of histone modifiers, can induce the complex immune response pattern of endotoxin tolerance in mammary epithelial cells. Innate Immun (2016) 0.75
Decreased cytokine production by mononuclear cells after severe gram-negative infections: early clinical signs and association with final outcome. Crit Care (2017) 0.75
Role of Leptin and SOCS3 in Inhibiting the Type I Interferon Response During Obesity. Inflammation (2016) 0.75
The Toll for Trafficking: Toll-Like Receptor 7 Delivery to the Endosome. Front Immunol (2017) 0.75
Severe sepsis and septic shock. N Engl J Med (2013) 14.31
Melioidosis: insights into the pathogenicity of Burkholderia pseudomallei. Nat Rev Microbiol (2006) 6.34
Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock. Nat Med (2007) 5.47
Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney. J Clin Invest (2005) 3.48
Alveolar macrophages have a protective antiinflammatory role during murine pneumococcal pneumonia. Am J Respir Crit Care Med (2002) 3.27
Bidirectional relation between inflammation and coagulation. Circulation (2004) 3.00
In vivo expression of Toll-like receptor 2 and 4 by renal epithelial cells: IFN-gamma and TNF-alpha mediated up-regulation during inflammation. J Immunol (2002) 2.76
IL-10 is an important mediator of the enhanced susceptibility to pneumococcal pneumonia after influenza infection. J Immunol (2004) 2.59
Inflammation, endothelium, and coagulation in sepsis. J Leukoc Biol (2007) 2.46
Role of toll-like receptors 2 and 4, and the receptor for advanced glycation end products in high-mobility group box 1-induced inflammation in vivo. Shock (2009) 2.26
Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents alveolar coagulation in patients without lung injury. Anesthesiology (2006) 2.19
Inflammation and coagulation. Crit Care Med (2010) 2.11
Diabetes does not alter mortality or hemostatic and inflammatory responses in patients with severe sepsis. Crit Care Med (2010) 2.11
Severe sepsis and septic shock. N Engl J Med (2013) 2.10
Hyperglycemia enhances coagulation and reduces neutrophil degranulation, whereas hyperinsulinemia inhibits fibrinolysis during human endotoxemia. Blood (2008) 2.03
The cholinergic anti-inflammatory pathway regulates the host response during septic peritonitis. J Infect Dis (2005) 2.02
Interobserver agreement of Centers for Disease Control and Prevention criteria for classifying infections in critically ill patients. Crit Care Med (2013) 2.02
Effects on coagulation and fibrinolysis induced by influenza in mice with a reduced capacity to generate activated protein C and a deficiency in plasminogen activator inhibitor type 1. Circ Res (2006) 1.95
The influence of corticosteroids on the release of novel biomarkers in human endotoxemia. Intensive Care Med (2007) 1.92
Toll-like receptor 2 plays a role in the early inflammatory response to murine pneumococcal pneumonia but does not contribute to antibacterial defense. J Immunol (2004) 1.91
Identification of a genetic determinant in clinical Enterococcus faecium strains that contributes to intestinal colonization during antibiotic treatment. J Infect Dis (2013) 1.90
Pathogenesis and pathophysiology of pneumococcal meningitis. Clin Microbiol Rev (2011) 1.87
Nuclear receptors Nur77, Nurr1, and NOR-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses. Arterioscler Thromb Vasc Biol (2006) 1.87
Stimulation of nicotinic acetylcholine receptors attenuates collagen-induced arthritis in mice. Arthritis Rheum (2009) 1.87
Lymphocytopenia and neutrophil-lymphocyte count ratio predict bacteremia better than conventional infection markers in an emergency care unit. Crit Care (2010) 1.86
Protective immune responses to a recombinant adenovirus type 35 tuberculosis vaccine in two mouse strains: CD4 and CD8 T-cell epitope mapping and role of gamma interferon. Infect Immun (2007) 1.85
Local activation of the tissue factor-factor VIIa pathway in patients with pneumonia and the effect of inhibition of this pathway in murine pneumococcal pneumonia. Crit Care Med (2006) 1.82
Host genetic susceptibility to pneumococcal and meningococcal disease: a systematic review and meta-analysis. Lancet Infect Dis (2008) 1.78
Toll-like receptor-4 coordinates the innate immune response of the kidney to renal ischemia/reperfusion injury. PLoS One (2008) 1.76
β₂-glycoprotein I: a novel component of innate immunity. Blood (2011) 1.75
Acute pancreatitis in mice impairs bacterial clearance from the lungs, whereas concurrent pneumonia prolongs the course of pancreatitis. Crit Care Med (2004) 1.73
Role of Toll-like receptor 4 in gram-positive and gram-negative pneumonia in mice. Infect Immun (2004) 1.73
The MyD88-dependent, but not the MyD88-independent, pathway of TLR4 signaling is important in clearing nontypeable haemophilus influenzae from the mouse lung. J Immunol (2005) 1.65
Acute phase response impairs host defense against Pseudomonas aeruginosa pneumonia in mice. Crit Care Med (2008) 1.64
Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents pulmonary inflammation in patients without preexisting lung injury. Anesthesiology (2008) 1.63
Two-way interactions between inflammation and coagulation. Trends Cardiovasc Med (2005) 1.63
Early endotoxemia increases peripheral and hepatic insulin sensitivity in healthy humans. J Clin Endocrinol Metab (2008) 1.61
Antiinflammatory effects of salmeterol after inhalation of lipopolysaccharide by healthy volunteers. Am J Respir Crit Care Med (2005) 1.60
Local stimulation of alpha7 cholinergic receptors inhibits LPS-induced TNF-alpha release in the mouse lung. Shock (2007) 1.59
Low molecular weight heparin attenuates multiple organ failure in a murine model of disseminated intravascular coagulation. Crit Care Med (2005) 1.58
Antithrombin inhibits bronchoalveolar activation of coagulation and limits lung injury during Streptococcus pneumoniae pneumonia in rats. Crit Care Med (2008) 1.58
Toll-like receptor 2 impairs host defense in gram-negative sepsis caused by Burkholderia pseudomallei (Melioidosis). PLoS Med (2007) 1.58
Complement deficiency states and associated infections. Mol Immunol (2011) 1.57
Host-pathogen interaction in invasive Salmonellosis. PLoS Pathog (2012) 1.57
Differential roles of CD14 and toll-like receptors 4 and 2 in murine Acinetobacter pneumonia. Am J Respir Crit Care Med (2005) 1.56
Role of interleukin-1 in the pulmonary immune response during Pseudomonas aeruginosa pneumonia. Am J Physiol Lung Cell Mol Physiol (2002) 1.56
Activation of coagulation and inhibition of fibrinolysis in the human lung on bronchial instillation of lipoteichoic acid and lipopolysaccharide. Crit Care Med (2009) 1.55
Pulmonary activation of coagulation and inhibition of fibrinolysis after burn injuries and inhalation trauma. J Trauma (2011) 1.54
Anti-inflammatory effects of a p38 mitogen-activated protein kinase inhibitor during human endotoxemia. J Immunol (2002) 1.51
The thiazolidinedione ciglitazone reduces bacterial outgrowth and early inflammation during Streptococcus pneumoniae pneumonia in mice. Crit Care Med (2009) 1.50
Serial changes in soluble triggering receptor expressed on myeloid cells in the lung during development of ventilator-associated pneumonia. Intensive Care Med (2005) 1.48
Induction of IRAK-M is associated with lipopolysaccharide tolerance in a human endotoxemia model. J Immunol (2007) 1.48
Ligands of the receptor for advanced glycation end products, including high-mobility group box 1, limit bacterial dissemination during Escherichia coli peritonitis. Crit Care Med (2010) 1.47
Loss of suppression of tumorigenicity 2 (ST2) gene reverses sepsis-induced inhibition of lung host defense in mice. Am J Respir Crit Care Med (2010) 1.46
Aspiration pneumonitis primes the host for an exaggerated inflammatory response during pneumonia. Crit Care Med (2005) 1.46
Glyburide is anti-inflammatory and associated with reduced mortality in melioidosis. Clin Infect Dis (2011) 1.45
Cutting edge: expression patterns of surface and soluble triggering receptor expressed on myeloid cells-1 in human endotoxemia. J Immunol (2004) 1.45
Reduced Responsiveness of Blood Leukocytes to Lipopolysaccharide Does not Predict Nosocomial Infections in Critically Ill Patients. Shock (2015) 1.44
A tick mannose-binding lectin inhibitor interferes with the vertebrate complement cascade to enhance transmission of the lyme disease agent. Cell Host Microbe (2011) 1.44
Anti-tumor necrosis factor antibody impairs the therapeutic effect of ceftriaxone in murine pneumococcal pneumonia. J Infect Dis (2003) 1.44
Dobutamine does not influence inflammatory pathways during human endotoxemia. Crit Care Med (2006) 1.44
The systemic pro-inflammatory response in sepsis. J Innate Immun (2010) 1.43
Salp15 binding to DC-SIGN inhibits cytokine expression by impairing both nucleosome remodeling and mRNA stabilization. PLoS Pathog (2008) 1.43
IL-18 improves the early antimicrobial host response to pneumococcal pneumonia. J Immunol (2002) 1.43
Endogenous tissue-type plasminogen activator impairs host defense during severe experimental Gram-negative sepsis (melioidosis)*. Crit Care Med (2012) 1.41
Influenza-induced expression of indoleamine 2,3-dioxygenase enhances interleukin-10 production and bacterial outgrowth during secondary pneumococcal pneumonia. J Infect Dis (2005) 1.41
The Selective Sirtuin 1 Activator SRT2104 Reduces Endotoxin-Induced Cytokine Release and Coagulation Activation in Humans. Crit Care Med (2015) 1.41
Monocyte chemoattractant protein 1 contributes to an adequate immune response in influenza pneumonia. Clin Immunol (2007) 1.40
Intestinal Enterococcus faecium colonization improves host defense during polymicrobial peritonitis. J Infect Dis (2009) 1.40
Sepsis and disseminated intravascular coagulation. J Thromb Thrombolysis (2004) 1.36
Neutrophil-derived S100A12 in acute lung injury and respiratory distress syndrome. Crit Care Med (2007) 1.34
MyD88 dependent signaling contributes to protective host defense against Burkholderia pseudomallei. PLoS One (2008) 1.33
TLR4 promotes fibrosis but attenuates tubular damage in progressive renal injury. J Am Soc Nephrol (2010) 1.32
The influence of pre-existing diabetes mellitus on the host immune response and outcome of pneumonia: analysis of two multicentre cohort studies. Thorax (2010) 1.31
Aggravation of endotoxin-induced disseminated intravascular coagulation and cytokine activation in heterozygous protein-C-deficient mice. Blood (2003) 1.31
Pulmonary Mycobacterium tuberculosis infection in leptin-deficient ob/ob mice. Int Immunol (2005) 1.30
Matrix metalloproteinase-9 deficiency impairs host defense against abdominal sepsis. J Immunol (2006) 1.29
Bronchoalveolar coagulation and fibrinolysis in endotoxemia and pneumonia. Crit Care Med (2003) 1.28
The acute-phase response and serum amyloid A inhibit the inflammatory response to Acinetobacter baumannii Pneumonia. J Infect Dis (2005) 1.28
Lipopolysaccharide (LPS)-binding protein mediates LPS detoxification by chylomicrons. J Immunol (2003) 1.26
Improved host defense against pneumococcal pneumonia in platelet-activating factor receptor-deficient mice. J Infect Dis (2004) 1.26
Pneumococcal meningitis in adults: new approaches to management and prevention. Lancet Neurol (2006) 1.26
The receptor for advanced glycation end products impairs host defense in pneumococcal pneumonia. J Immunol (2009) 1.25
The neutrophil-lymphocyte count ratio in patients with community-acquired pneumonia. PLoS One (2012) 1.24
The role of Toll-like receptor 2 in inflammation and fibrosis during progressive renal injury. PLoS One (2009) 1.22
Inflammation patterns induced by different Burkholderia species in mice. Cell Microbiol (2007) 1.22
Hyperglycemia stimulates coagulation, whereas hyperinsulinemia impairs fibrinolysis in healthy humans. Diabetes (2006) 1.22
Lipoteichoic acid-induced lung inflammation depends on TLR2 and the concerted action of TLR4 and the platelet-activating factor receptor. J Immunol (2008) 1.22
Plasminogen activator inhibitor type 1 is protective during severe Gram-negative pneumonia. Blood (2006) 1.21
Ventilator-induced lung injury is mediated by the NLRP3 inflammasome. Anesthesiology (2012) 1.21
Immunity to Burkholderia pseudomallei. Curr Opin Infect Dis (2009) 1.21
Identification and characterization of Ixodes scapularis antigens that elicit tick immunity using yeast surface display. PLoS One (2011) 1.21
Tissue factor in infection and severe inflammation. Semin Thromb Hemost (2006) 1.20