Malonyl-CoA decarboxylase inhibition is selectively cytotoxic to human breast cancer cells.

PubWeight™: 0.93‹?›

🔗 View Article (PMID 19543323)

Published in Oncogene on June 22, 2009

Authors

W Zhou1, Y Tu, P J Simpson, F P Kuhajda

Author Affiliations

1: Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA.

Articles by these authors

(truncated to the top 100)

Green fluorescent protein as a marker for gene expression. Science (1994) 34.55

Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells. J Exp Med (2001) 5.66

Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors. Science (2000) 4.62

Identification, purification, and partial characterization of a novel Mr 28,000 integral membrane protein from erythrocytes and renal tubules. J Biol Chem (1988) 3.83

Modeling of DNA microarray data by using physical properties of hybridization. Proc Natl Acad Sci U S A (2003) 2.95

Impact of the patient population on the risk for heparin-induced thrombocytopenia. Blood (2000) 2.78

Analysis of donor return behavior. Retrovirus Epidemiology Donor Study. Transfusion (1999) 2.22

Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts. Cancer Res (2000) 2.21

Knowledge of HIV/AIDS transmission and screening in United States blood donors. Transfusion (2001) 2.20

Inhibition of fatty acid synthesis delays disease progression in a xenograft model of ovarian cancer. Cancer Res (1996) 2.18

First year donation patterns predict long-term commitment for first-time donors. Vox Sang (2005) 2.18

Weighted evolving networks. Phys Rev Lett (2001) 2.07

Cooperative interactions between the Caenorhabditis elegans homeoproteins UNC-86 and MEC-3. Science (1993) 2.07

Syringe labelling--an international standard. Anaesthesia (2003) 2.02

Mechanotransduction in bone: osteoblasts are more responsive to fluid forces than mechanical strain. Am J Physiol (1997) 1.98

Elevated expression of fatty acid synthase and fatty acid synthetic activity in colorectal neoplasia. Am J Pathol (1997) 1.93

Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation. Nat Cell Biol (2000) 1.89

Analysis of gene expression microarrays for phenotype classification. Proc Int Conf Intell Syst Mol Biol (2000) 1.82

Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis. Oncogene (2009) 1.76

Relationship between gene expression and observed intensities in DNA microarrays--a modeling study. Nucleic Acids Res (2006) 1.74

Enzymes of the fatty acid synthesis pathway are highly expressed in in situ breast carcinoma. Clin Cancer Res (1997) 1.70

Mitochondrial dynamics regulates migration and invasion of breast cancer cells. Oncogene (2012) 1.69

Inhibition of fatty acid synthesis induces programmed cell death in human breast cancer cells. Cancer Res (1996) 1.69

Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at square root of s = 7 TeV. Phys Rev Lett (2010) 1.67

The XRCC2 DNA repair gene from human and mouse encodes a novel member of the recA/RAD51 family. Nucleic Acids Res (1998) 1.60

MRCP of congenital pancreaticobiliary malformation. Abdom Imaging (2007) 1.58

Study of the mass and spin-parity of the Higgs boson candidate via its decays to Z boson pairs. Phys Rev Lett (2013) 1.56

Obese gene expression at in vivo levels by fat pads derived from s.c. implanted 3T3-F442A preadipocytes. Proc Natl Acad Sci U S A (1997) 1.55

Cyanide and thiocyanate concentrations following sodium nitroprusside infusion in man. Br J Anaesth (1976) 1.54

Comparison of immunoperoxidase and DNA in situ hybridization techniques in the diagnosis of cytomegalovirus colitis. Am J Clin Pathol (1988) 1.46

Free radicals and myocardial ischemia and reperfusion injury. J Lab Clin Med (1987) 1.45

Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity. Biochem Biophys Res Commun (2001) 1.40

BMP-12 gene transfer augmentation of lacerated tendon repair. J Orthop Res (2001) 1.36

Interleukin-6 inhibits apoptosis of malignant plasma cells. Cell Immunol (1995) 1.35

Fatty acid synthase (FAS): a target for cytotoxic antimetabolites in HL60 promyelocytic leukemia cells. Cancer Res (1996) 1.34

Apoptotic vs. nonapoptotic cytotoxicity induced by hydrogen peroxide. Free Radic Biol Med (1997) 1.33

Evidence for synergy between family 2b carbohydrate binding modules in Cellulomonas fimi xylanase 11A. Biochemistry (2001) 1.31

Computed tomography of extracranial nerve sheath tumors with pathological correlation. J Comput Assist Tomogr (1983) 1.29

In vitro cytoreductive effects on multiple myeloma cells induced by bisphosphonates. Leukemia (1998) 1.27

Isolation of novel human and mouse genes of the recA/RAD51 recombination-repair gene family. Nucleic Acids Res (1998) 1.27

Corynebacterium mooreparkense sp. nov. and Corynebacterium casei sp. nov., isolated from the surface of a smear-ripened cheese. Int J Syst Evol Microbiol (2001) 1.26

The starch-binding domain from glucoamylase disrupts the structure of starch. FEBS Lett (1999) 1.26

Carbohydrate-binding modules from a thermostable Rhodothermus marinus xylanase: cloning, expression and binding studies. Biochem J (2000) 1.26

Measurement of the electron charge asymmetry in inclusive W production in pp collisions at sqrt[s]=7  TeV. Phys Rev Lett (2012) 1.23

Regulator of G-protein signaling 2 (RGS2) inhibits androgen-independent activation of androgen receptor in prostate cancer cells. Oncogene (2006) 1.23

Solution structure of the CBM10 cellulose binding module from Pseudomonas xylanase A. Biochemistry (2000) 1.20

Search for new physics in the multijet and missing transverse momentum final state in proton-proton collisions at √s = 7 TeV. Phys Rev Lett (2012) 1.19

Azimuthal anisotropy of charged particles at high transverse momenta in Pb-Pb collisions at sqrt[s(NN)] = 2.76  TeV. Phys Rev Lett (2012) 1.19

Clostridium thermocellum Xyn10B carbohydrate-binding module 22-2: the role of conserved amino acids in ligand binding. Biochemistry (2001) 1.19

RGSZ1, a Gz-selective RGS protein in brain. Structure, membrane association, regulation by Galphaz phosphorylation, and relationship to a Gz gtpase-activating protein subfamily. J Biol Chem (1998) 1.19

Fatty acid synthase expression in endometrial carcinoma: correlation with cell proliferation and hormone receptors. Cancer (1998) 1.18

Relationships of x-irradiation to the enhancement of Candida albicans infections. J Bacteriol (1967) 1.16

The type II and X cellulose-binding domains of Pseudomonas xylanase A potentiate catalytic activity against complex substrates by a common mechanism. Biochem J (1999) 1.15

Structure of pp32, an acidic nuclear protein which inhibits oncogene-induced formation of transformed foci. Mol Biol Cell (1996) 1.13

Involvement of ERK in BMP-2 induced osteoblastic differentiation of mesenchymal progenitor cell line C3H10T1/2. Biochem Biophys Res Commun (2000) 1.13

Measurement of the WW + WZ production cross section using the lepton + jets final state at CDF II. Phys Rev Lett (2010) 1.12

First observation of the decay Bs0-->Ds-Ds+ and measurement of its branching ratio. Phys Rev Lett (2008) 1.11

Fatty acid synthase (FAS) expression in human breast cancer cell culture supernatants and in breast cancer patients. Cancer Lett (2001) 1.10

Search for a W' or techni-ρ decaying into WZ in pp Collisions at sqrt[s] = 7  TeV. Phys Rev Lett (2012) 1.10

Multiple myeloma cells are protected against dexamethasone-induced apoptosis by insulin-like growth factors. Br J Haematol (1997) 1.09

Search for new physics with same-sign isolated dilepton events with jets and missing transverse energy. Phys Rev Lett (2012) 1.09

Structure and developmental regulation of the B-lymphoid tyrosine kinase gene blk. J Biol Chem (1992) 1.09

Formation of novel polymeric nanoparticles. Acc Chem Res (2001) 1.09

Search for supersymmetry at the LHC in events with jets and missing transverse energy. Phys Rev Lett (2011) 1.08

Search for stopped Gluinos in pp collisions at square root s=7 TeV. Phys Rev Lett (2011) 1.07

Iloprost inhibits neutrophil function in vitro and in vivo and limits experimental infarct size in canine heart. Circ Res (1987) 1.06

Blocking of heart allograft rejection by intercellular adhesion molecule-1 antisense oligonucleotides alone or in combination with other immunosuppressive modalities. J Immunol (1994) 1.05

Deficiency of leukocyte surface glycoproteins Mo1, LFA-1, and Leu M5 in a dog with recurrent bacterial infections: an animal model. Blood (1987) 1.05

Esthesioneuroblastoma. Intermediate filaments, neuroendocrine, and tissue-specific antigens. Am J Clin Pathol (1987) 1.05

Inhibition of transcription factor binding by ultraviolet-induced pyrimidine dimers. Biochemistry (1996) 1.05

Measurement of the Υ1S, Υ2S, and Υ3S polarizations in pp collisions at sqrt[s] = 7 TeV. Phys Rev Lett (2013) 1.05

Direct measurement of the W production charge asymmetry in pp collisions at square root s=1.96 TeV. Phys Rev Lett (2009) 1.04

Expression of oncogenic antigen 519 (OA-519) in prostate cancer is a potential prognostic indicator. Am J Clin Pathol (1992) 1.04

Alkaloids of Acronychia Baueri Schott I. Isolation of the alkaloids and a study of the antitumor and other biological properties of acronycine. J Pharm Sci (1966) 1.03

Search for long-lived massive charged particles in 1.96 TeV pp collisions. Phys Rev Lett (2009) 1.03

Role of hydrogen bonding in the interaction between a xylan binding module and xylan. Biochemistry (2001) 1.02

Trp22, Trp24, and Tyr8 play a pivotal role in the binding of the family 10 cellulose-binding module from Pseudomonas xylanase A to insoluble ligands. Biochemistry (2000) 1.01

Antimycobacterial activity of cerulenin and its effects on lipid biosynthesis. J Antimicrob Chemother (1999) 1.01

Interleukin-6-induced inhibition of multiple myeloma cell apoptosis: support for the hypothesis that protection is mediated via inhibition of the JNK/SAPK pathway. Blood (1998) 1.01

Binocular cues and the control of prehension. Spat Vis (2004) 1.01

Alterations in glutamatergic and gabaergic ion channel activity in hippocampal neurons following exposure to the abused inhalant toluene. Neuroscience (2005) 1.00

Prostacyclin protects ischemic reperfused myocardium in the dog by inhibition of neutrophil activation. Am Heart J (1987) 1.00

Collagen triple helix repeat containing-1 inhibits transforming growth factor-b1-induced collagen type I expression in keloid. Br J Dermatol (2011) 1.00

Measurement of the polarization of W bosons with large transverse momenta in W + jets events at the LHC. Phys Rev Lett (2011) 0.99

Erythropoietin prevents reactive oxygen species generation and renal tubular cell apoptosis at high glucose level. Biomed Pharmacother (2010) 0.99

The distribution of carcinoembryonic antigen in breast carcinoma. Diagnostic and prognostic implications. Cancer (1983) 0.99

Solitary bronchioloalveolar carcinoma: CT criteria. Radiology (1988) 0.98

Active and passive particles: modeling beads in a bacterial bath. Phys Rev E Stat Nonlin Soft Matter Phys (2001) 0.98

Measurement of the inclusive jet cross section in pp collisions at √s = 7 TeV. Phys Rev Lett (2011) 0.98

Warthin's tumor-associated neoplasms: report of two cases and review of the literature. Ear Nose Throat J (1993) 0.98

Search for neutral minimal supersymmetric standard model Higgs bosons decaying to tau pairs in pp collisions at √s=7 TeV. Phys Rev Lett (2011) 0.97

Novel nuclear phosphoprotein pp32 is highly expressed in intermediate- and high-grade prostate cancer. Prostate (1998) 0.97

Localization to chromosome 7q36.1 of the human XRCC2 gene, determining sensitivity to DNA-damaging agents. Hum Mol Genet (1995) 0.97

Search for large extra dimensions in final states containing one photon or jet and large missing transverse energy produced in pp collisions at square root[s]=1.96 TeV. Phys Rev Lett (2008) 0.97

Increased fatty acid synthase is a therapeutic target in mesothelioma. Clin Cancer Res (2001) 0.97

Polarizations of J/psi and psi(2S) mesons produced in pp collisions at square root s = 1.96 TeV. Phys Rev Lett (2007) 0.96

Antiplatelet antibody [7E3 F(ab')2] prevents rethrombosis after recombinant tissue-type plasminogen activator-induced coronary artery thrombolysis in a canine model. Circulation (1990) 0.96

Free radical scavengers in myocardial ischemia. Fed Proc (1987) 0.96

Diffuse cavernous hemangioma of the rectosigmoid colon. Tech Coloproctol (2005) 0.95

Measurement of associated production of vector bosons and top quark-antiquark pairs in pp collisions at sqrt[s]=7  TeV. Phys Rev Lett (2013) 0.95