|
1
|
Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.
|
Nat Genet
|
2013
|
2.60
|
|
2
|
Juvenile idiopathic arthritis and HLA class I and class II interactions and age-at-onset effects.
|
Arthritis Rheum
|
2010
|
1.99
|
|
3
|
Subtype-specific peripheral blood gene expression profiles in recent-onset juvenile idiopathic arthritis.
|
Arthritis Rheum
|
2009
|
1.56
|
|
4
|
ImmunoChip study implicates antigen presentation to T cells in narcolepsy.
|
PLoS Genet
|
2013
|
1.55
|
|
5
|
Juvenile rheumatoid arthritis affected sibpairs: extent of clinical phenotype concordance.
|
Arthritis Rheum
|
2004
|
1.50
|
|
6
|
Increased prevalence of familial autoimmunity in simplex and multiplex families with juvenile rheumatoid arthritis.
|
Arthritis Rheum
|
2002
|
1.47
|
|
7
|
Macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis is associated with MUNC13-4 polymorphisms.
|
Arthritis Rheum
|
2008
|
1.33
|
|
8
|
Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry.
|
Nat Genet
|
2011
|
1.30
|
|
9
|
Association of the IL2RA/CD25 gene with juvenile idiopathic arthritis.
|
Arthritis Rheum
|
2009
|
1.23
|
|
10
|
The -174G allele of the interleukin-6 gene confers susceptibility to systemic arthritis in children: a multicenter study using simplex and multiplex juvenile idiopathic arthritis families.
|
Arthritis Rheum
|
2003
|
1.20
|
|
11
|
Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets.
|
Arthritis Rheum
|
2009
|
1.15
|
|
12
|
Interferon-gamma:interleukin 4 ratios and associated type 1 cytokine expression in juvenile rheumatoid arthritis synovial tissue.
|
J Rheumatol
|
2002
|
1.14
|
|
13
|
Follistatin-like protein 1 is a mesenchyme-derived inflammatory protein and may represent a biomarker for systemic-onset juvenile rheumatoid arthritis.
|
Arthritis Rheum
|
2010
|
1.10
|
|
14
|
Antibodies against cyclic citrullinated peptide are associated with HLA-DR4 in simplex and multiplex polyarticular-onset juvenile rheumatoid arthritis.
|
Arthritis Rheum
|
2005
|
1.02
|
|
15
|
Immature cell populations and an erythropoiesis gene-expression signature in systemic juvenile idiopathic arthritis: implications for pathogenesis.
|
Arthritis Res Ther
|
2010
|
1.01
|
|
16
|
Investigation of rheumatoid arthritis susceptibility loci in juvenile idiopathic arthritis confirms high degree of overlap.
|
Ann Rheum Dis
|
2012
|
1.01
|
|
17
|
Association of the 5-aminoimidazole-4-carboxamide ribonucleotide transformylase gene with response to methotrexate in juvenile idiopathic arthritis.
|
Ann Rheum Dis
|
2011
|
1.00
|
|
18
|
Hierarchy of risk of childhood-onset rheumatoid arthritis conferred by HLA-DRB1 alleles encoding the shared epitope.
|
Arthritis Rheum
|
2012
|
0.98
|
|
19
|
Biologic similarities based on age at onset in oligoarticular and polyarticular subtypes of juvenile idiopathic arthritis.
|
Arthritis Rheum
|
2010
|
0.97
|
|
20
|
Generation of novel pharmacogenomic candidates in response to methotrexate in juvenile idiopathic arthritis: correlation between gene expression and genotype.
|
Pharmacogenet Genomics
|
2010
|
0.97
|
|
21
|
Susceptibility to childhood-onset rheumatoid arthritis: investigation of a weighted genetic risk score that integrates cumulative effects of variants at five genetic loci.
|
Arthritis Rheum
|
2013
|
0.93
|
|
22
|
Sequence feature variant type (SFVT) analysis of the HLA genetic association in juvenile idiopathic arthritis.
|
Pac Symp Biocomput
|
2010
|
0.91
|
|
23
|
A functional RANKL polymorphism associated with younger age at onset of rheumatoid arthritis.
|
Arthritis Rheum
|
2010
|
0.87
|
|
24
|
Secondary analysis of APPLE study suggests atorvastatin may reduce atherosclerosis progression in pubertal lupus patients with higher C reactive protein.
|
Ann Rheum Dis
|
2013
|
0.86
|
|
25
|
Multiple juvenile idiopathic arthritis subtypes demonstrate proinflammatory IgG glycosylation.
|
Arthritis Rheum
|
2012
|
0.85
|
|
26
|
Synovial fluid proteins differentiate between the subtypes of juvenile idiopathic arthritis.
|
Arthritis Rheum
|
2010
|
0.82
|
|
27
|
Gene Expression Profiles from Peripheral Blood Mononuclear Cells Are Sensitive to Short Processing Delays.
|
Biopreserv Biobank
|
2010
|
0.82
|
|
28
|
Lack of association of functional CTLA4 polymorphisms with juvenile idiopathic arthritis.
|
Arthritis Rheum
|
2008
|
0.82
|
|
29
|
Familial autoimmunity: maternal parent-of-origin effect in juvenile idiopathic arthritis.
|
Clin Rheumatol
|
2007
|
0.81
|
|
30
|
Genetics of juvenile idiopathic arthritis: new tools bring new approaches.
|
Curr Opin Rheumatol
|
2014
|
0.80
|
|
31
|
Follistatin-like protein 1 and the ferritin/erythrocyte sedimentation rate ratio are potential biomarkers for dysregulated gene expression and macrophage activation syndrome in systemic juvenile idiopathic arthritis.
|
J Rheumatol
|
2013
|
0.79
|
|
32
|
Genomic progress in pediatric arthritis: recent work and future goals.
|
Curr Opin Rheumatol
|
2006
|
0.78
|
|
33
|
Tapasin gene polymorphism in systemic onset juvenile rheumatoid arthritis: a family-based case-control study.
|
Arthritis Res Ther
|
2005
|
0.78
|
|
34
|
Autoinflammatory gene polymorphisms and susceptibility to UK juvenile idiopathic arthritis.
|
Pediatr Rheumatol Online J
|
2013
|
0.75
|