Published in J Cell Biochem on September 01, 2009
miR-29 is a major regulator of genes associated with pulmonary fibrosis. Am J Respir Cell Mol Biol (2010) 2.87
miR-29 modulates Wnt signaling in human osteoblasts through a positive feedback loop. J Biol Chem (2010) 2.05
MicroRNA control of bone formation and homeostasis. Nat Rev Endocrinol (2012) 2.05
Identification of microRNA-regulated gene networks by expression analysis of target genes. Genome Res (2012) 1.51
A microRNA expression signature of osteoclastogenesis. Blood (2011) 1.49
MicroRNAs differentially expressed in postnatal aortic development downregulate elastin via 3' UTR and coding-sequence binding sites. PLoS One (2011) 1.41
Role of miR-29b on the regulation of the extracellular matrix in human trabecular meshwork cells under chronic oxidative stress. Mol Vis (2009) 1.39
Molecular and functional characteristics of ovarian surface epithelial cells transformed by KrasG12D and loss of Pten in a mouse model in vivo. Oncogene (2011) 1.29
Regulation of gene expression in osteoblasts. Biofactors (2010) 1.23
Coordinated regulation of extracellular matrix synthesis by the microRNA-29 family in the trabecular meshwork. Invest Ophthalmol Vis Sci (2011) 1.15
MicroRNA biogenesis and regulation of bone remodeling. Arthritis Res Ther (2011) 1.11
Cross-talk between miR-29 and transforming growth factor-betas in trabecular meshwork cells. Invest Ophthalmol Vis Sci (2011) 1.11
Differential expression of exosomal microRNAs in prefrontal cortices of schizophrenia and bipolar disorder patients. PLoS One (2013) 1.06
MiR-27a targets sFRP1 in hFOB cells to regulate proliferation, apoptosis and differentiation. PLoS One (2014) 1.04
MicroRNA in cardiovascular calcification: focus on targets and extracellular vesicle delivery mechanisms. Circ Res (2013) 1.02
Reduction of Dicer impairs Schwann cell differentiation and myelination. J Neurosci Res (2010) 0.99
Thrombospondin-2 and SPARC/osteonectin are critical regulators of bone remodeling. J Cell Commun Signal (2009) 0.98
Integrative nucleophosmin mutation-associated microRNA and gene expression pattern analysis identifies novel microRNA - target gene interactions in acute myeloid leukemia. Haematologica (2011) 0.98
miR-214 promotes osteoclastogenesis by targeting Pten/PI3k/Akt pathway. RNA Biol (2015) 0.97
Periosteum derived stem cells for regenerative medicine proposals: Boosting current knowledge. World J Stem Cells (2014) 0.97
Therapeutic Opportunities for Targeting microRNAs in Cancer. Mol Cell Ther (2014) 0.94
Role of heme oxygenase-1 in postnatal differentiation of stem cells: a possible cross-talk with microRNAs. Antioxid Redox Signal (2014) 0.94
MicroRNAs as novel regulators of stem cell fate. World J Stem Cells (2013) 0.94
miR-29 promotes murine osteoclastogenesis by regulating osteoclast commitment and migration. J Biol Chem (2013) 0.92
miR-29a/b enhances cell migration and invasion in nasopharyngeal carcinoma progression by regulating SPARC and COL3A1 gene expression. PLoS One (2015) 0.92
MicroRNAs involved in bone formation. Cell Mol Life Sci (2014) 0.92
Integrin β4 regulates SPARC protein to promote invasion. J Biol Chem (2012) 0.91
MicroRNAs regulate bone metabolism. J Bone Miner Metab (2013) 0.91
MicroRNAs as regulators of bone homeostasis and bone metastasis. Bonekey Rep (2014) 0.90
microRNA-29 negatively regulates EMT regulator N-myc interactor in breast cancer. Mol Cancer (2014) 0.90
Inhibition of miR-21 restores RANKL/OPG ratio in multiple myeloma-derived bone marrow stromal cells and impairs the resorbing activity of mature osteoclasts. Oncotarget (2015) 0.86
SPARC promotes leukemic cell growth and predicts acute myeloid leukemia outcome. J Clin Invest (2014) 0.86
From cellular senescence to age-associated diseases: the miRNA connection. Longev Healthspan (2012) 0.85
Mir-29 repression in bladder outlet obstruction contributes to matrix remodeling and altered stiffness. PLoS One (2013) 0.85
Canonical wnt signaling regulates extracellular matrix expression in the trabecular meshwork. Invest Ophthalmol Vis Sci (2014) 0.85
IGF-I 3' untranslated region: strain-specific polymorphisms and motifs regulating IGF-I in osteoblasts. Endocrinology (2012) 0.84
The role of microRNAs in bone remodeling. Int J Oral Sci (2015) 0.84
MicroRNAs regulate bone development and regeneration. Int J Mol Sci (2015) 0.84
Photoactivated miR-148b-nanoparticle conjugates improve closure of critical size mouse calvarial defects. Acta Biomater (2014) 0.84
Non-housekeeping genes expressed in human trabecular meshwork cell cultures. Mol Vis (2012) 0.84
MicroRNA-mediated regulation of differentiation and trans-differentiation in stem cells. Adv Drug Deliv Rev (2015) 0.83
miR-195 in human primary mesenchymal stromal/stem cells regulates proliferation, osteogenesis and paracrine effect on angiogenesis. Oncotarget (2016) 0.83
MicroRNAs Regulate Vascular Medial Calcification. Cells (2014) 0.83
Vitamin D and microRNAs in bone. Crit Rev Eukaryot Gene Expr (2013) 0.83
HIV and Bone Disease: A Perspective of the Role of microRNAs in Bone Biology upon HIV Infection. J Osteoporos (2013) 0.83
Bone matrix osteonectin limits prostate cancer cell growth and survival. Matrix Biol (2012) 0.82
A single nucleotide polymorphism in osteonectin 3' untranslated region regulates bone volume and is targeted by miR-433. J Bone Miner Res (2015) 0.81
The two faces of miR-29. J Cardiovasc Med (Hagerstown) (2015) 0.81
Post-transcriptional regulation in osteoblasts using localized delivery of miR-29a inhibitor from nanofibers to enhance extracellular matrix deposition. Acta Biomater (2014) 0.81
miR-29a modulates neuronal differentiation through targeting REST in mesenchymal stem cells. PLoS One (2014) 0.81
Global miRNA expression and correlation with mRNA levels in primary human bone cells. RNA (2015) 0.80
Mechanotransduction in musculoskeletal tissue regeneration: effects of fluid flow, loading, and cellular-molecular pathways. Biomed Res Int (2014) 0.80
Targeting oncomiRNAs and mimicking tumor suppressor miRNAs: Νew trends in the development of miRNA therapeutic strategies in oncology (Review). Int J Oncol (2016) 0.79
MicroRNAs' Involvement in Osteoarthritis and the Prospects for Treatments. Evid Based Complement Alternat Med (2015) 0.79
COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients. BMC Med Genet (2014) 0.79
The microRNA-29 family in cartilage homeostasis and osteoarthritis. J Mol Med (Berl) (2015) 0.78
Human bone marrow stromal cell confluence: effects on cell characteristics and methods of assessment. Cytotherapy (2015) 0.77
Developing novel anti-fibrotic therapeutics to modulate post-surgical wound healing in glaucoma: big potential for small molecules. Expert Rev Ophthalmol (2015) 0.77
Serum microRNA is a promising biomarker for osteogenesis imperfecta. Intractable Rare Dis Res (2012) 0.76
Protective effects of miR-29a on diabetic glomerular dysfunction by modulation of DKK1/Wnt/β-catenin signaling. Sci Rep (2016) 0.76
SPARC/osteonectin in mineralized tissue. Matrix Biol (2016) 0.76
Evaluation of miR-29c inhibits endotheliocyte migration and angiogenesis of human endothelial cells by suppressing the insulin like growth factor 1. Am J Transl Res (2015) 0.76
Recent highlights on bone stem cells: a report from Bone Stem Cells 2009, and not only…. J Cell Mol Med (2010) 0.76
Cross-talk of MicroRNA and hydrogen sulfide: A novel therapeutic approach for bone diseases. Biomed Pharmacother (2017) 0.76
MicroRNA-29b Overexpression Decreases Extracellular Matrix mRNA and Protein Production in Human Corneal Endothelial Cells. Cornea (2016) 0.75
The Role of miRNAs in Cartilage Homeostasis. Curr Genomics (2015) 0.75
miR-29a Participated in Nacre Formation and Immune Response by Targeting Y2R in Pinctada martensii. Int J Mol Sci (2015) 0.75
Evaluation of miR-29c inhibits endotheliocyte migration and angiogenesis of human endothelial cells by suppressing the insulin like growth factor 1. Am J Transl Res (2015) 0.75
MicroRNAs and Bone Regeneration. Curr Genomics (2015) 0.75
MiR-218 Induces Neuronal Differentiation of ASCs in a Temporally Sequential Manner with Fibroblast Growth Factor by Regulation of the Wnt Signaling Pathway. Sci Rep (2017) 0.75
MiR-153 Regulates Amelogenesis by Targeting Endocytotic and Endosomal/lysosomal Pathways-Novel Insight into the Origins of Enamel Pathologies. Sci Rep (2017) 0.75
MicroRNAs: Potential Biomarkers and Therapeutic Targets for Alveolar Bone Loss in Periodontal Disease. Int J Mol Sci (2016) 0.75
Pathophysiological Responses in Rat and Mouse Models of Radiation-Induced Brain Injury. Mol Neurobiol (2016) 0.75
Dicer ablation in osteoblasts by Runx2 driven cre-loxP recombination affects bone integrity, but not glucocorticoid-induced suppression of bone formation. Sci Rep (2016) 0.75
Interleukin-32 Gamma Stimulates Bone Formation by Increasing miR-29a in Osteoblastic Cells and Prevents the Development of Osteoporosis. Sci Rep (2017) 0.75
miR-125a-3p targetedly regulates GIT1 expression to inhibit osteoblastic proliferation and differentiation. Exp Ther Med (2016) 0.75
Bone marrow stroma-derived miRNAs as regulators, biomarkers and therapeutic targets of bone metastasis. Bonekey Rep (2015) 0.75
Role of the microRNA-29 family in fibrotic skin diseases. Biomed Rep (2017) 0.75
microRNA Regulation of Skeletal Development. Curr Osteoporos Rep (2017) 0.75
MicroRNAs in bone diseases. Osteoporos Int (2016) 0.75
MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 198.59
Prediction of mammalian microRNA targets. Cell (2003) 53.70
MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol Cell (2007) 38.42
Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs. Nat Rev Genet (2004) 12.97
Widespread microRNA repression by Myc contributes to tumorigenesis. Nat Genet (2007) 10.78
Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. Proc Natl Acad Sci U S A (2008) 9.86
Involvement of microRNA in AU-rich element-mediated mRNA instability. Cell (2005) 9.01
Illuminating the silence: understanding the structure and function of small RNAs. Nat Rev Mol Cell Biol (2007) 6.11
A hexanucleotide element directs microRNA nuclear import. Science (2007) 5.71
NF-kappaB-YY1-miR-29 regulatory circuitry in skeletal myogenesis and rhabdomyosarcoma. Cancer Cell (2008) 4.57
The 3' untranslated region of messenger RNA: A molecular 'hotspot' for pathology? Nat Med (2000) 4.11
MicroRNA 29c is down-regulated in nasopharyngeal carcinomas, up-regulating mRNAs encoding extracellular matrix proteins. Proc Natl Acad Sci U S A (2008) 4.06
SPARC, a matricellular protein that functions in cellular differentiation and tissue response to injury. J Clin Invest (2001) 3.13
Molecular mechanisms mediating proliferation/differentiation interrelationships during progressive development of the osteoblast phenotype. Endocr Rev (1993) 2.52
The extracellular glycoprotein SPARC interacts with platelet-derived growth factor (PDGF)-AB and -BB and inhibits the binding of PDGF to its receptors. Proc Natl Acad Sci U S A (1992) 1.94
Expression profile of osteoblast lineage at defined stages of differentiation. J Biol Chem (2005) 1.83
Matricellular proteins: Extracellular modulators of bone development, remodeling, and regeneration. Bone (2006) 1.72
Osteopenia and decreased bone formation in osteonectin-deficient mice. J Clin Invest (2000) 1.70
SPARC regulates processing of procollagen I and collagen fibrillogenesis in dermal fibroblasts. J Biol Chem (2007) 1.68
Real-time quantitative RT-PCR analysis of human bone marrow stromal cells during osteogenic differentiation in vitro. J Cell Biochem (2002) 1.66
Beta-catenin levels influence rapid mechanical responses in osteoblasts. J Biol Chem (2008) 1.60
Roles of Wnt signalling in bone growth, remodelling, skeletal disorders and fracture repair. J Cell Physiol (2008) 1.47
Functional mapping of SPARC: peptides from two distinct Ca+(+)-binding sites modulate cell shape. J Cell Biol (1990) 1.44
Infrared analysis of the mineral and matrix in bones of osteonectin-null mice and their wildtype controls. J Bone Miner Res (2003) 1.39
Osteonectin-null mutation compromises osteoblast formation, maturation, and survival. Endocrinology (2003) 1.37
Osteonectin cDNA sequence reveals potential binding regions for calcium and hydroxyapatite and shows homologies with both a basement membrane protein (SPARC) and a serine proteinase inhibitor (ovomucoid). Proc Natl Acad Sci U S A (1988) 1.30
Targeting SPARC expression decreases glioma cellular survival and invasion associated with reduced activities of FAK and ILK kinases. Oncogene (2007) 1.30
Distribution of the calcium-binding protein SPARC in tissues of embryonic and adult mice. J Histochem Cytochem (1989) 1.24
Characterization of the mouse SPARC/osteonectin gene. Intron/exon organization and an unusual promoter region. J Biol Chem (1988) 1.15
Inhibition of PDGF-stimulated and matrix-mediated proliferation of human vascular smooth muscle cells by SPARC is independent of changes in cell shape or cyclin-dependent kinase inhibitors. J Cell Biochem (2002) 1.08
SPARC-induced migration of glioblastoma cell lines via uPA-uPAR signaling and activation of small GTPase RhoA. Int J Oncol (2006) 1.06
SPARC is a VCAM-1 counter-ligand that mediates leukocyte transmigration. J Leukoc Biol (2006) 1.06
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Expression of the osteonectin gene potentially controlled by multiple cis- and trans-acting factors in cultured bone cells. J Bone Miner Res (1991) 0.97
Increased Notch 1 expression and attenuated stimulatory G protein coupling to adenylyl cyclase in osteonectin-null osteoblasts. Endocrinology (2007) 0.96
A purine-rich sequence in the human BM-40 gene promoter region is a prerequisite for maximum transcription. Matrix Biol (1995) 0.95
Evidence for positive and negative regulatory elements in the 5'-flanking sequence of the mouse sparc (osteonectin) gene. J Biol Chem (1989) 0.94
Osteonectin/SPARC polymorphisms in Caucasian men with idiopathic osteoporosis. Osteoporos Int (2007) 0.94
Accentuated osteoclastic response to parathyroid hormone undermines bone mass acquisition in osteonectin-null mice. Bone (2008) 0.93
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Retroposons do jump: a B2 element recently integrated in an 18S rDNA gene. Nucleic Acids Res (1992) 0.92
Molecular docking and analysis of interactions between vascular endothelial growth factor (VEGF) and SPARC protein. J Mol Graph Model (2007) 0.90
Osteopenia in Sparc (osteonectin)-deficient mice: characterization of phenotypic determinants of femoral strength and changes in gene expression. Physiol Genomics (2007) 0.88
Basic fibroblast growth factor destabilizes osteonectin mRNA in osteoblasts. Am J Physiol (1998) 0.87
miR-29 modulates Wnt signaling in human osteoblasts through a positive feedback loop. J Biol Chem (2010) 2.05
Notch 1 impairs osteoblastic cell differentiation. Endocrinology (2003) 1.57
Infrared analysis of the mineral and matrix in bones of osteonectin-null mice and their wildtype controls. J Bone Miner Res (2003) 1.39
Mechanisms of glucocorticoid action in bone. Ann N Y Acad Sci (2002) 1.39
CCAAT/enhancer binding protein homologous protein (DDIT3) induces osteoblastic cell differentiation. Endocrinology (2003) 1.21
MicroRNA biogenesis and regulation of bone remodeling. Arthritis Res Ther (2011) 1.11
Nocturnin suppresses igf1 expression in bone by targeting the 3' untranslated region of igf1 mRNA. Endocrinology (2010) 1.00
Thrombospondin-2 and SPARC/osteonectin are critical regulators of bone remodeling. J Cell Commun Signal (2009) 0.98
Cortisol regulates the expression of Notch in osteoblasts. J Cell Biochem (2002) 0.97
Increased Notch 1 expression and attenuated stimulatory G protein coupling to adenylyl cyclase in osteonectin-null osteoblasts. Endocrinology (2007) 0.96
AU-rich elements in the collagenase 3 mRNA mediate stabilization of the transcript by cortisol in osteoblasts. J Biol Chem (2003) 0.95
Accentuated osteoclastic response to parathyroid hormone undermines bone mass acquisition in osteonectin-null mice. Bone (2008) 0.93
miR-29 promotes murine osteoclastogenesis by regulating osteoclast commitment and migration. J Biol Chem (2013) 0.92
Inactivation of SPARC enhances high-fat diet-induced obesity in mice. Connect Tissue Res (2010) 0.88
IGF-I 3' untranslated region: strain-specific polymorphisms and motifs regulating IGF-I in osteoblasts. Endocrinology (2012) 0.84
Effects of glucocorticoids on the skeleton. J Pediatr Endocrinol Metab (2002) 0.84
Bone matrix osteonectin limits prostate cancer cell growth and survival. Matrix Biol (2012) 0.82
A single nucleotide polymorphism in osteonectin 3' untranslated region regulates bone volume and is targeted by miR-433. J Bone Miner Res (2015) 0.81
11beta-hydroxysteroid dehydrogenase, an amplifier of glucocorticoid action in osteoblasts. J Bone Miner Res (2002) 0.76