Jacob Piehler

Author PubWeight™ 72.09‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Helical structures of ESCRT-III are disassembled by VPS4. Science 2008 3.38
2 Structural linkage between ligand discrimination and receptor activation by type I interferons. Cell 2011 2.39
3 High-affinity adaptors for switchable recognition of histidine-tagged proteins. J Am Chem Soc 2005 2.06
4 Inquiring into the differential action of interferons (IFNs): an IFN-alpha2 mutant with enhanced affinity to IFNAR1 is functionally similar to IFN-beta. Mol Cell Biol 2006 1.82
5 Differential receptor subunit affinities of type I interferons govern differential signal activation. J Mol Biol 2006 1.67
6 USP18-based negative feedback control is induced by type I and type III interferons and specifically inactivates interferon α response. PLoS One 2011 1.60
7 Specific and stable fluorescence labeling of histidine-tagged proteins for dissecting multi-protein complex formation. J Am Chem Soc 2006 1.53
8 The stability of the ternary interferon-receptor complex rather than the affinity to the individual subunits dictates differential biological activities. J Biol Chem 2008 1.33
9 Cell-free production of G protein-coupled receptors for functional and structural studies. J Struct Biol 2007 1.24
10 Fluorescence microscopy assays on chemically functionalized surfaces for quantitative imaging of microtubule, motor, and +TIP dynamics. Methods Cell Biol 2010 1.23
11 Ligand-induced assembling of the type I interferon receptor on supported lipid bilayers. J Mol Biol 2004 1.17
12 High-affinity labeling and tracking of individual histidine-tagged proteins in live cells using Ni2+ tris-nitrilotriacetic acid quantum dot conjugates. Nano Lett 2009 1.13
13 Functional cartography of the ectodomain of the type I interferon receptor subunit ifnar1. J Mol Biol 2005 1.12
14 Structure of Aquifex aeolicus argonaute highlights conformational flexibility of the PAZ domain as a potential regulator of RNA-induced silencing complex function. J Biol Chem 2006 1.10
15 Ultrathin nucleoporin phenylalanine-glycine repeat films and their interaction with nuclear transport receptors. EMBO Rep 2010 1.10
16 High-affinity chelator thiols for switchable and oriented immobilization of histidine-tagged proteins: a generic platform for protein chip technologies. Chemistry 2005 1.10
17 Arginine- and lysine-specific polymers for protein recognition and immobilization. J Am Chem Soc 2006 1.09
18 Processive kinesins require loose mechanical coupling for efficient collective motility. EMBO Rep 2008 1.07
19 Self-controlled monofunctionalization of quantum dots for multiplexed protein tracking in live cells. Angew Chem Int Ed Engl 2010 1.07
20 Covalent monofunctionalization of peptide-coated quantum dots for single-molecule assays. Nano Lett 2010 1.05
21 Triple-color super-resolution imaging of live cells: resolving submicroscopic receptor organization in the plasma membrane. Angew Chem Int Ed Engl 2012 1.04
22 Determination of the two-dimensional interaction rate constants of a cytokine receptor complex. Biophys J 2006 1.04
23 Ligand binding induces a conformational change in ifnar1 that is propagated to its membrane-proximal domain. J Mol Biol 2008 1.02
24 The EM structure of a type I interferon-receptor complex reveals a novel mechanism for cytokine signaling. J Mol Biol 2007 0.99
25 Lateral ligand-receptor interactions on membranes probed by simultaneous fluorescence-interference detection. Biophys J 2005 0.99
26 Stable and functional immobilization of histidine-tagged proteins via multivalent chelator headgroups on a molecular poly(ethylene glycol) brush. Anal Chem 2005 0.98
27 Native protein nanolithography that can write, read and erase. Nat Nanotechnol 2007 0.97
28 In situ assembly of macromolecular complexes triggered by light. Proc Natl Acad Sci U S A 2010 0.96
29 The Mon1-Ccz1 GEF activates the Rab7 GTPase Ypt7 via a longin-fold-Rab interface and association with PI3P-positive membranes. J Cell Sci 2014 0.96
30 Noncovalent, site-specific biotinylation of histidine-tagged proteins. Anal Chem 2007 0.96
31 Monitoring the dynamics of ligand-receptor complexes on model membranes. J Am Chem Soc 2006 0.93
32 Four-color single-molecule fluorescence with noncovalent dye labeling to monitor dynamic multimolecular complexes. Biotechniques 2010 0.92
33 Accelerating phage-display library selection by reversible and site-specific biotinylation. Protein Eng Des Sel 2009 0.90
34 TRF1 and TRF2 use different mechanisms to find telomeric DNA but share a novel mechanism to search for protein partners at telomeres. Nucleic Acids Res 2013 0.89
35 Nanoscale organization of mitochondrial microcompartments revealed by combining tracking and localization microscopy. Nano Lett 2012 0.88
36 Functional immobilization and patterning of proteins by an enzymatic transfer reaction. Anal Chem 2010 0.87
37 Differential protein assembly on micropatterned surfaces with tailored molecular and surface multivalency. Chembiochem 2006 0.86
38 Photopatterned surfaces for site-specific and functional immobilization of proteins. Langmuir 2007 0.85
39 Selective targeting of fluorescent nanoparticles to proteins inside live cells. Angew Chem Int Ed Engl 2011 0.84
40 Imaging the invisible: resolving cellular microcompartments by superresolution microscopy techniques. Biol Chem 2013 0.84
41 Electrostatically controlled quantum dot monofunctionalization for interrogating the dynamics of protein complexes in living cells. ACS Chem Biol 2012 0.84
42 Native laser lithography of His-tagged proteins by uncaging of multivalent chelators. J Am Chem Soc 2010 0.84
43 Affinity capturing for targeting proteins into micro and nanostructures. Anal Bioanal Chem 2009 0.83
44 Piezo dispensed microarray of multivalent chelating thiols for dissecting complex protein-protein interactions. Anal Chem 2006 0.83
45 Self-assembled monolayers containing terminal mono-, bis-, and tris-nitrilotriacetic acid groups: characterization and application. Langmuir 2008 0.82
46 Spatial organization of lipid phases in micropatterned polymer-supported membranes. J Am Chem Soc 2013 0.82
47 NMR mapping of the IFNAR1-EC binding site on IFNalpha2 reveals allosteric changes in the IFNAR2-EC binding site. Biochemistry 2010 0.81
48 Modulating surface density of proteins via caged surfaces and controlled light exposure. Langmuir 2011 0.81
49 Dynamic submicroscopic signaling zones revealed by pair correlation tracking and localization microscopy. Anal Chem 2014 0.81
50 High-fidelity protein targeting into membrane lipid microdomains in living cells. Angew Chem Int Ed Engl 2013 0.81
51 Multiple targets for suppression of RNA interference by tomato aspermy virus protein 2B. Biochemistry 2008 0.80
52 Probing 2-dimensional protein-protein interactions on model membranes. Nat Protoc 2006 0.80
53 Quantitative real-time imaging of protein-protein interactions by LSPR detection with micropatterned gold nanoparticles. Anal Chem 2013 0.80
54 Conformation of receptor adopted upon interaction with virus revealed by site-specific fluorescence quenchers and FRET analysis. J Am Chem Soc 2009 0.80
55 Reprint of "Cell-free production of G protein-coupled receptors for functional and structural studies" [J. Struct. Biol. 158 (2007) 482-493]. J Struct Biol 2007 0.80
56 Selectivity of competitive multivalent interactions at interfaces. Chembiochem 2009 0.80
57 Maleimide photolithography for single-molecule protein-protein interaction analysis in micropatterns. Anal Chem 2010 0.79
58 Probing protein conformations by in situ non-covalent fluorescence labeling. Bioconjug Chem 2009 0.79
59 Reconstitution of membrane proteins into polymer-supported membranes for probing diffusion and interactions by single molecule techniques. Anal Chem 2011 0.79
60 GPCRs: Caught in a spectroscopic trap. Nat Chem Biol 2011 0.79
61 Organization of motor proteins into functional micropatterns fabricated by a photoinduced Fenton reaction. Angew Chem Int Ed Engl 2009 0.79
62 Rapid transfer of transmembrane proteins for single molecule dimerization assays in polymer-supported membranes. ACS Chem Biol 2014 0.79
63 Multivalent chelators for spatially and temporally controlled protein functionalization. Anal Bioanal Chem 2014 0.78
64 Diffusion and interaction dynamics of individual membrane protein complexes confined in micropatterned polymer-supported membranes. Small 2012 0.78
65 Protein tyrosine phosphatase SHP2/PTPN11 mistargeting as a consequence of SH2-domain point mutations associated with Noonan Syndrome and leukemia. J Proteomics 2013 0.78
66 Addressable adsorption of lipid vesicles and subsequent protein interaction studies. Biointerphases 2008 0.77
67 Differential activity of type I interferon subtypes for dendritic cell differentiation. PLoS One 2013 0.77
68 Protein-protein interactions in reversibly assembled nanopatterns. Nano Lett 2008 0.77
69 A versatile toolbox for multiplexed protein micropatterning by laser lithography. Small 2012 0.77
70 Synthesis of a multivalent chelator lipid for stably tethering histidine-tagged proteins onto membranes. Nat Protoc 2006 0.77
71 Clustering and dynamics of phototransducer signaling domains revealed by site-directed spin labeling electron paramagnetic resonance on SRII/HtrII in membranes and nanodiscs. Biochemistry 2014 0.76
72 Monofunctional stealth nanoparticle for unbiased single molecule tracking inside living cells. Nano Lett 2014 0.75
73 Hybrid electron microscopy-FRET imaging localizes the dynamical C-terminus of Tfg2 in RNA polymerase II-TFIIF with nanometer precision. J Struct Biol 2013 0.75
74 Bioinspired monolithic polymer microsphere arrays as generically anti-adhesive surfaces. Bioinspir Biomim 2016 0.75