PubRank

Irmgard Sinning

Author PubWeight™ 93.95‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Following the signal sequence from ribosomal tunnel exit to signal recognition particle. Nature 2006 2.11
2 Distinct modes of signal recognition particle interaction with the ribosome. Science 2002 2.08
3 Delivering proteins for export from the cytosol. Nat Rev Mol Cell Biol 2009 2.00
4 High-resolution X-ray and NMR structures of the SMN Tudor domain: conformational variation in the binding site for symmetrically dimethylated arginine residues. J Mol Biol 2003 1.84
5 Structure and dynamics of the ATP-bound open conformation of Hsp70 chaperones. Mol Cell 2012 1.84
6 Signal recognition particle receptor exposes the ribosomal translocon binding site. Science 2006 1.77
7 Signal peptide peptidase (SPP) assembles with substrates and misfolded membrane proteins into distinct oligomeric complexes. Biochem J 2010 1.68
8 Structural basis for tail-anchored membrane protein biogenesis by the Get3-receptor complex. Science 2011 1.68
9 Structural insights into tail-anchored protein binding and membrane insertion by Get3. Proc Natl Acad Sci U S A 2009 1.63
10 Membrane curvature induced by Arf1-GTP is essential for vesicle formation. Proc Natl Acad Sci U S A 2008 1.63
11 SRP-mediated protein targeting: structure and function revisited. Biochim Biophys Acta 2004 1.57
12 Crystal structure of the complete core of archaeal signal recognition particle and implications for interdomain communication. Proc Natl Acad Sci U S A 2003 1.55
13 The structure of a pH-sensing mycobacterial adenylyl cyclase holoenzyme. Science 2005 1.52
14 Substrate binding disrupts dimerization and induces nucleotide exchange of the chloroplast GTPase Toc33. Biochem J 2011 1.49
15 The C terminus of the Alb3 membrane insertase recruits cpSRP43 to the thylakoid membrane. J Biol Chem 2009 1.49
16 Signal recognition particle mediates post-translational targeting in eukaryotes. EMBO J 2004 1.46
17 Protein targeting by the signal recognition particle. Biol Chem 2009 1.39
18 Molecular basis for the unique role of the AAA+ chaperone ClpV in type VI protein secretion. J Biol Chem 2011 1.37
19 FlhA provides the adaptor for coordinated delivery of late flagella building blocks to the type III secretion system. Proc Natl Acad Sci U S A 2010 1.35
20 A direct role for phosphatidylinositol-4,5-bisphosphate in unconventional secretion of fibroblast growth factor 2. Traffic 2008 1.33
21 Canonical signal recognition particle components can be bypassed for posttranslational protein targeting in chloroplasts. Plant Cell 2007 1.31
22 SRP meets the ribosome. Nat Struct Mol Biol 2004 1.18
23 Escherichia coli signal recognition particle receptor FtsY contains an essential and autonomous membrane-binding amphipathic helix. J Biol Chem 2007 1.17
24 Structural basis for specific substrate recognition by the chloroplast signal recognition particle protein cpSRP43. Science 2008 1.15
25 Structure of a bacterial pyridoxal 5'-phosphate synthase complex. Proc Natl Acad Sci U S A 2006 1.14
26 The structure of the mammalian signal recognition particle (SRP) receptor as prototype for the interaction of small GTPases with Longin domains. J Biol Chem 2006 1.14
27 Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2. EMBO Rep 2008 1.13
28 Glutamate-binding affinity of Drosophila metabotropic glutamate receptor is modulated by association with lipid rafts. Proc Natl Acad Sci U S A 2003 1.10
29 Vitamin B6 biosynthesis by the malaria parasite Plasmodium falciparum: biochemical and structural insights. J Biol Chem 2005 1.05
30 cpSRP43 is a novel chaperone specific for light-harvesting chlorophyll a,b-binding proteins. J Biol Chem 2010 1.05
31 Structural analysis of the human Golgi-associated plant pathogenesis related protein GAPR-1 implicates dimerization as a regulatory mechanism. J Mol Biol 2004 1.04
32 The crystal structure of Ebp1 reveals a methionine aminopeptidase fold as binding platform for multiple interactions. FEBS Lett 2007 1.04
33 The structure of Get4 reveals an alpha-solenoid fold adapted for multiple interactions in tail-anchored protein biogenesis. FEBS Lett 2010 1.03
34 The GTPase cycle of the chloroplast import receptors Toc33/Toc34: implications from monomeric and dimeric structures. Structure 2008 1.03
35 Structural characterization of a eukaryotic chaperone--the ribosome-associated complex. Nat Struct Mol Biol 2012 1.03
36 Reconstituted TOM core complex and Tim9/Tim10 complex of mitochondria are sufficient for translocation of the ADP/ATP carrier across membranes. Mol Biol Cell 2003 1.02
37 Synchronizing nuclear import of ribosomal proteins with ribosome assembly. Science 2012 1.02
38 Membrane targeting of ribosomes and their release require distinct and separable functions of FtsY. J Biol Chem 2007 0.98
39 The crystal structure of the periplasmic domain of the Escherichia coli membrane protein insertase YidC contains a substrate binding cleft. J Biol Chem 2008 0.97
40 Towards the structure of the mammalian signal recognition particle. Curr Opin Struct Biol 2002 0.97
41 A structural step into the SRP cycle. Mol Microbiol 2004 0.97
42 Endoplasmic reticulum targeting and insertion of tail-anchored membrane proteins by the GET pathway. Cold Spring Harb Perspect Biol 2013 0.96
43 Structural basis for the molecular evolution of SRP-GTPase activation by protein. Nat Struct Mol Biol 2011 0.96
44 The crystal structure of the third signal-recognition particle GTPase FlhF reveals a homodimer with bound GTP. Proc Natl Acad Sci U S A 2007 0.96
45 Conserved properties of polypeptide transport-associated (POTRA) domains derived from cyanobacterial Omp85. J Biol Chem 2010 0.96
46 An extended helical conformation in domain 3a of Munc18-1 provides a template for SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex assembly. J Biol Chem 2014 0.93
47 New twist to nuclear import: When two travel together. Commun Integr Biol 2013 0.90
48 Genetic evidence for functional interaction of the Escherichia coli signal recognition particle receptor with acidic lipids in vivo. J Biol Chem 2010 0.89
49 X-ray crystal structure of Saccharomyces cerevisiae Pdx1 provides insights into the oligomeric nature of PLP synthases. FEBS Lett 2009 0.89
50 Consistent mutational paths predict eukaryotic thermostability. BMC Evol Biol 2013 0.89
51 The structure of the chloroplast signal recognition particle (SRP) receptor reveals mechanistic details of SRP GTPase activation and a conserved membrane targeting site. FEBS Lett 2007 0.89
52 Lipids trigger a conformational switch that regulates signal recognition particle (SRP)-mediated protein targeting. J Biol Chem 2011 0.89
53 Chromodomains read the arginine code of post-translational targeting. Nat Struct Mol Biol 2012 0.89
54 Choline head groups stabilize the matrix loop regions of the ATP/ADP carrier ScAAC2. Biochem Biophys Res Commun 2003 0.88
55 Longin and GAF domains: structural evolution and adaptation to the subcellular trafficking machinery. Traffic 2013 0.88
56 Structure and conservation of the periplasmic targeting factor Tic22 protein from plants and cyanobacteria. J Biol Chem 2012 0.88
57 Arabidopsis stromal-derived Factor2 (SDF2) is a crucial target of the unfolded protein response in the endoplasmic reticulum. J Biol Chem 2010 0.87
58 Crystallization of the crenarchaeal SRP core. Acta Crystallogr D Biol Crystallogr 2003 0.86
59 On the significance of Toc-GTPase homodimers. J Biol Chem 2008 0.86
60 SIMIBI twins in protein targeting and localization. Nat Struct Mol Biol 2013 0.86
61 Assembly of the eukaryotic PLP-synthase complex from Plasmodium and activation of the Pdx1 enzyme. Structure 2012 0.85
62 Mdm38 is a 14-3-3-like receptor and associates with the protein synthesis machinery at the inner mitochondrial membrane. Traffic 2011 0.85
63 SRP RNA remodeling by SRP68 explains its role in protein translocation. Science 2014 0.85
64 Functional reconstitution of purified metabotropic glutamate receptor expressed in the fly eye. EMBO Rep 2002 0.85
65 Overproduction, purification, crystallization and preliminary X-ray analysis of human Fe65-PTB2 in complex with the amyloid precursor protein intracellular domain. Acta Crystallogr Sect F Struct Biol Cryst Commun 2008 0.84
66 Phosphorylation of LRP1 regulates the interaction with Fe65. FEBS Lett 2011 0.82
67 Crystal structure of the human Fe65-PTB1 domain. J Biol Chem 2008 0.82
68 The structure of the regulatory domain of the adenylyl cyclase Rv1264 from Mycobacterium tuberculosis with bound oleic acid. J Mol Biol 2007 0.81
69 Structural insights into the assembly of the human and archaeal signal recognition particles. Acta Crystallogr D Biol Crystallogr 2010 0.81
70 RNA gymnastics in mammalian signal recognition particle assembly. RNA Biol 2014 0.81
71 Pharmacological characterization and immunoaffinity purification of metabotropic glutamate receptor from Drosophila overexpressed in Sf9 cells. Protein Expr Purif 2003 0.81
72 Protein translocation: checkpoint role for SRP GTPase activation. Curr Biol 2007 0.80
73 Structural basis for a distinct catalytic mechanism in Trypanosoma brucei tryparedoxin peroxidase. J Biol Chem 2008 0.80
74 Drosophila photoreceptor cells exploited for the production of eukaryotic membrane proteins: receptors, transporters and channels. PLoS One 2011 0.80
75 Binding of chloroplast signal recognition particle to a thylakoid membrane protein substrate in aqueous solution and delineation of the cpSRP43-substrate interaction domain. Biochem J 2011 0.80
76 Cloning, recombinant production, crystallization and preliminary X-ray diffraction analysis of SDF2-like protein from Arabidopsis thaliana. Acta Crystallogr Sect F Struct Biol Cryst Commun 2009 0.78
77 Defining the structural requirements for ribose 5-phosphate-binding and intersubunit cross-talk of the malarial pyridoxal 5-phosphate synthase. FEBS Lett 2010 0.78
78 Expression, purification and preliminary crystallographic characterization of FlhF from Bacillus subtilis. Acta Crystallogr Sect F Struct Biol Cryst Commun 2007 0.78
79 Purification, crystallization and preliminary structural characterization of the periplasmic domain P1 of the Escherichia coli membrane-protein insertase YidC. Acta Crystallogr Sect F Struct Biol Cryst Commun 2008 0.78
80 Definition of domain boundaries and crystallization of the SMN Tudor domain. Acta Crystallogr D Biol Crystallogr 2003 0.78
81 The C terminus of Alb3 interacts with the chromodomains 2 and 3 of cpSRP43. J Biol Chem 2010 0.78
82 Crystallization of a Golgi-associated PR-1-related protein (GAPR-1) that localizes to lipid-enriched microdomains. Acta Crystallogr D Biol Crystallogr 2004 0.77
83 Structural biology. Surprising news from the PCC. Science 2004 0.77
84 Targeting of Drosophila rhodopsin requires helix 8 but not the distal C-terminus. PLoS One 2009 0.76
85 Expression, purification, crystallization and preliminary crystallographic analysis of the proliferation-associated protein Ebp1. Acta Crystallogr Sect F Struct Biol Cryst Commun 2007 0.76
86 Membrane protein expression in the eyes of transgenic flies. Methods Mol Biol 2010 0.76
87 Signal sequences get active. Nat Chem Biol 2009 0.75
88 Mercury-induced crystallization and SAD phasing of the human Fe65-PTB1 domain. Acta Crystallogr Sect F Struct Biol Cryst Commun 2008 0.75