Regulatory mechanism of NFATc1 in RANKL-induced osteoclast activation.

PubWeight™: 1.05‹?› | Rank: Top 15%

🔗 View Article (PMID 19576893)

Published in FEBS Lett on July 02, 2009

Authors

Insun Song1, Jung Ha Kim, Kabsun Kim, Hye Mi Jin, Bang Ung Youn, Nacksung Kim

Author Affiliations

1: National Research Laboratory for Regulation of Bone Metabolism and Disease, Medical Research Center for Gene Regulation, Brain Korea 21, Chonnam National University Medical School, 5 Hak-Dong, Dong-Ku, Gwangju 501-746, Republic of Korea.

Articles citing this

Bone cell interactions through Eph/ephrin: bone modeling, remodeling and associated diseases. Cell Adh Migr (2012) 1.18

Osteoclast fusion and regulation by RANKL-dependent and independent factors. World J Orthop (2012) 1.11

Wnt Signaling Inhibits Osteoclast Differentiation by Activating Canonical and Noncanonical cAMP/PKA Pathways. J Bone Miner Res (2015) 0.90

Bone structure and B-cell populations, crippled by obesity, are partially rescued by brief daily exposure to low-magnitude mechanical signals. FASEB J (2012) 0.89

Molecular mechanisms of triggering, amplifying and targeting RANK signaling in osteoclasts. World J Orthop (2012) 0.86

Notch signaling in skeletal stem cells. Calcif Tissue Int (2013) 0.86

The adaptor protein p62/SQSTM1 in osteoclast signaling pathways. J Mol Signal (2012) 0.86

Stage-specific functions of leukemia/lymphoma-related factor (LRF) in the transcriptional control of osteoclast development. Proc Natl Acad Sci U S A (2012) 0.84

Kinsenoside prevents ovariectomy-induced bone loss and suppresses osteoclastogenesis by regulating classical NF-κB pathways. Osteoporos Int (2012) 0.82

Regulators of G protein signaling 12 promotes osteoclastogenesis in bone remodeling and pathological bone loss. Cell Death Differ (2015) 0.81

Response of a preosteoblastic cell line to cyclic tensile stress conditioning and growth factors for bone tissue engineering. Tissue Eng Part A (2011) 0.80

Alternative NF-κB Regulates RANKL-Induced Osteoclast Differentiation and Mitochondrial Biogenesis via Independent Mechanisms. J Bone Miner Res (2015) 0.80

Genistein attenuates glucocorticoid-induced bone deleterious effects through regulation Eph/ephrin expression in aged mice. Int J Clin Exp Pathol (2015) 0.79

Micromolar sodium fluoride mediates anti-osteoclastogenesis in Porphyromonas gingivalis-induced alveolar bone loss. Int J Oral Sci (2015) 0.79

The Roles of Acidosis in Osteoclast Biology. Front Physiol (2016) 0.78

Interleukin-4 inhibits RANKL-induced NFATc1 expression via STAT6: a novel mechanism mediating its blockade of osteoclastogenesis. J Cell Biochem (2011) 0.78

The dectin 1 agonist curdlan regulates osteoclastogenesis by inhibiting nuclear factor of activated T cells cytoplasmic 1 (NFATc1) through Syk kinase. J Biol Chem (2014) 0.77

Aconine inhibits RANKL-induced osteoclast differentiation in RAW264.7 cells by suppressing NF-κB and NFATc1 activation and DC-STAMP expression. Acta Pharmacol Sin (2015) 0.77

Caveolin-1 regulates osteoclast differentiation by suppressing cFms degradation. Exp Mol Med (2015) 0.75

E proteins regulate osteoclast maturation and survival. J Bone Miner Res (2012) 0.75

Selaginella tamariscina water extract inhibits receptor activator for the nuclear factor-κB ligand-induced osteoclast differentiation by blocking mitogen-activated protein kinase and NF-κB signaling. Pharmacogn Mag (2012) 0.75

Alpha-1 antitrypsin inhibits RANKL-induced osteoclast formation and functions. Mol Med (2017) 0.75

Articles by these authors

v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation. Nat Med (2006) 3.78

Osteoimmunology: interplay between the immune system and bone metabolism. Annu Rev Immunol (2006) 3.18

A crucial role for reactive oxygen species in RANKL-induced osteoclast differentiation. Blood (2005) 2.95

Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells. Blood (2007) 2.65

Inhibition of histone deacetylation blocks cardiac hypertrophy induced by angiotensin II infusion and aortic banding. Circulation (2005) 2.44

NFATc1 induces osteoclast fusion via up-regulation of Atp6v0d2 and the dendritic cell-specific transmembrane protein (DC-STAMP). Mol Endocrinol (2007) 2.25

Osteoclast differentiation independent of the TRANCE-RANK-TRAF6 axis. J Exp Med (2005) 2.21

Stimulation by toll-like receptors inhibits osteoclast differentiation. J Immunol (2002) 1.82

Nuclear factor of activated T cells c1 induces osteoclast-associated receptor gene expression during tumor necrosis factor-related activation-induced cytokine-mediated osteoclastogenesis. J Biol Chem (2005) 1.62

MafB negatively regulates RANKL-mediated osteoclast differentiation. Blood (2006) 1.60

Reactive oxygen species mediate RANK signaling in osteoclasts. Exp Cell Res (2004) 1.38

Id helix-loop-helix proteins negatively regulate TRANCE-mediated osteoclast differentiation. Blood (2005) 1.38

The mechanism of osteoclast differentiation induced by IL-1. J Immunol (2009) 1.33

Strength of TRAF6 signalling determines osteoclastogenesis. EMBO Rep (2005) 1.30

The tec family tyrosine kinase Btk Regulates RANKL-induced osteoclast maturation. J Biol Chem (2008) 1.29

Akt induces osteoclast differentiation through regulating the GSK3β/NFATc1 signaling cascade. J Immunol (2011) 1.20

Noninvasive real-time imaging of tumors and metastases using tumor-targeting light-emitting Escherichia coli. Mol Imaging Biol (2007) 1.16

Selective inhibition of RANK blocks osteoclast maturation and function and prevents bone loss in mice. J Clin Invest (2009) 1.15

Microphthalmia transcription factor and PU.1 synergistically induce the leukocyte receptor osteoclast-associated receptor gene expression. J Biol Chem (2003) 1.14

Bone destruction by receptor activator of nuclear factor κB ligand-expressing T cells in chronic gouty arthritis. Arthritis Res Ther (2011) 1.08

Numerical and functional deficiencies of natural killer T cells in systemic lupus erythematosus: their deficiency related to disease activity. Rheumatology (Oxford) (2011) 1.01

Histone methyltransferase PRDM8 regulates mouse testis steroidogenesis. Biochem Biophys Res Commun (2009) 1.01

Structure-based development of a receptor activator of nuclear factor-kappaB ligand (RANKL) inhibitor peptide and molecular basis for osteopetrosis. Proc Natl Acad Sci U S A (2010) 1.00

Enhancer of polycomb1, a novel homeodomain only protein-binding partner, induces skeletal muscle differentiation. J Biol Chem (2006) 0.98

Interleukin-4 inhibition of osteoclast differentiation is stronger than that of interleukin-13 and they are equivalent for induction of osteoprotegerin production from osteoblasts. Immunology (2007) 0.98

Gene expression profiling of osteoclast differentiation by combined suppression subtractive hybridization (SSH) and cDNA microarray analysis. DNA Cell Biol (2002) 0.98

Inactivation of glycogen synthase kinase-3β is required for osteoclast differentiation. J Biol Chem (2011) 0.94

MHC class II transactivator negatively regulates RANKL-mediated osteoclast differentiation by downregulating NFATc1 and OSCAR. Cell Signal (2010) 0.94

The role of RANKL (TRANCE/TNFSF11), a tumor necrosis factor family member, in skeletal development: effects of gene knockout and transgenic rescue. Connect Tissue Res (2003) 0.93

Identification of LRRc17 as a negative regulator of receptor activator of NF-kappaB ligand (RANKL)-induced osteoclast differentiation. J Biol Chem (2009) 0.92

Negative feedback control of osteoclast formation through ubiquitin-mediated down-regulation of NFATc1. J Biol Chem (2009) 0.91

Prognostic relevance of pathologic subtypes and minimal invasion in intraductal papillary mucinous neoplasms of the pancreas. Tumour Biol (2010) 0.90

Monokine induced by interferon-gamma is induced by receptor activator of nuclear factor kappa B ligand and is involved in osteoclast adhesion and migration. Blood (2004) 0.90

Protein inhibitor of activated STAT 3 modulates osteoclastogenesis by down-regulation of NFATc1 and osteoclast-associated receptor. J Immunol (2007) 0.90

MicroRNA-155 as a proinflammatory regulator via SHIP-1 down-regulation in acute gouty arthritis. Arthritis Res Ther (2014) 0.89

Early growth response 2 negatively modulates osteoclast differentiation through upregulation of Id helix-loop-helix proteins. Bone (2012) 0.89

Selenite-induced apoptosis of osteoclasts mediated by the mitochondrial pathway. Toxicol Lett (2005) 0.89

Pim-1 regulates RANKL-induced osteoclastogenesis via NF-κB activation and NFATc1 induction. J Immunol (2010) 0.89

Beta-catenin modulates the level and transcriptional activity of Notch1/NICD through its direct interaction. Biochim Biophys Acta (2008) 0.88

RANKL induces NFATc1 acetylation and stability via histone acetyltransferases during osteoclast differentiation. Biochem J (2011) 0.88

Modulation of the expression and transactivation of androgen receptor by the basic helix-loop-helix transcription factor Pod-1 through recruitment of histone deacetylase 1. Mol Endocrinol (2005) 0.88

Silibinin inhibits osteoclast differentiation mediated by TNF family members. Mol Cells (2009) 0.87

Natural killer T cell deficiency in active adult-onset Still's Disease: correlation of deficiency of natural killer T cells with dysfunction of natural killer cells. Arthritis Rheum (2012) 0.87

Black tea extract prevents lipopolysaccharide-induced NF-κB signaling and attenuates dextran sulfate sodium-induced experimental colitis. BMC Complement Altern Med (2011) 0.85

Oral alcohol administration disturbs tear film and ocular surface. Ophthalmology (2012) 0.85

Modulation of androgen receptor transactivation by the SWI3-related gene product (SRG3) in multiple ways. Mol Cell Biol (2005) 0.84

Ribavirin enhances osteoclast formation through osteoblasts via up-regulation of TRANCE/RANKL. Mol Cell Biochem (2006) 0.84

Inhibition of osteoclast differentiation and bone resorption by tanshinone IIA isolated from Salvia miltiorrhiza Bunge. Biochem Pharmacol (2004) 0.84

Maternal-fetal disposition of bisphenol a in pregnant Sprague-Dawley rats. J Toxicol Environ Health A (2002) 0.83

TRANCE-RANK costimulation is required for IL-12 production and the initiation of a Th1-type response to Leishmania major infection in CD40L-deficient mice. J Immunol (2003) 0.83

Inhibitory regulation of osteoclast differentiation by interleukin-3 via regulation of c-Fos and Id protein expression. J Cell Physiol (2012) 0.83

Mechanical and Histopathological Comparison between Commercialized and Newly Designed Coronary Bare Metal Stents in a Porcine Coronary Restenosis Model. Chonnam Med J (2013) 0.82

Kruppel-like factor 4 attenuates osteoblast formation, function, and cross talk with osteoclasts. J Cell Biol (2014) 0.82

Upstream stimulatory factors regulate OSCAR gene expression in RANKL-mediated osteoclast differentiation. J Mol Biol (2008) 0.82

Age- and gender-related differences in circulating natural killer T cells and their subset levels in healthy Korean adults. Hum Immunol (2012) 0.82

SLAT negatively regulates RANKL-induced osteoclast differentiation. Mol Cells (2013) 0.81

Effect of a dual drug-coated stent with abciximab and alpha-lipoic Acid in a porcine coronary restenosis model. Korean Circ J (2011) 0.81