Published in J Alzheimers Dis on January 01, 2009
Presenilin transgenic mice as models of Alzheimer's disease. Brain Struct Funct (2009) 0.98
Presenilin/gamma-Secretase and Inflammation. Front Aging Neurosci (2010) 0.79
Connectivity mapping (ssCMap) to predict A20-inducing drugs and their antiinflammatory action in cystic fibrosis. Proc Natl Acad Sci U S A (2016) 0.75
Ibuprofen rescues abnormalities in periodontal tissues in conditional presenilin 1 and presenilin 2 double knockout mice. Int J Mol Sci (2013) 0.75
The genetic landscape of a cell. Science (2010) 16.52
The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing Diabetes Prevention Study: a 20-year follow-up study. Lancet (2008) 9.03
The cost-effectiveness of lifestyle modification or metformin in preventing type 2 diabetes in adults with impaired glucose tolerance. Ann Intern Med (2005) 6.63
Costs associated with the primary prevention of type 2 diabetes mellitus in the diabetes prevention program. Diabetes Care (2003) 4.22
Socioeconomic status and trends in disparities in 4 major risk factors for cardiovascular disease among US adults, 1971-2002. Arch Intern Med (2006) 4.17
Radiolabeled cell distribution after intramyocardial, intracoronary, and interstitial retrograde coronary venous delivery: implications for current clinical trials. Circulation (2005) 3.61
Vasculotropic, paracrine actions of infused mesenchymal stem cells are important to the recovery from acute kidney injury. Am J Physiol Renal Physiol (2007) 3.54
Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development. Nat Med (2008) 3.33
The synthetic genetic interaction spectrum of essential genes. Nat Genet (2005) 3.06
The economic burden of major adult visual disorders in the United States. Arch Ophthalmol (2006) 2.92
Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity. Nat Med (2011) 2.82
Structural insights into the regulatory particle of the proteasome from Methanocaldococcus jannaschii. Mol Cell (2009) 2.75
Induction of pluripotency in human endothelial cells resets epigenetic profile on genome scale. Cell Cycle (2010) 2.64
Cost-effectiveness of interventions to prevent and control diabetes mellitus: a systematic review. Diabetes Care (2010) 2.49
Fatty acid desaturation links germ cell loss to longevity through NHR-80/HNF4 in C. elegans. PLoS Biol (2011) 2.32
Cost-effectiveness of screening for pre-diabetes among overweight and obese U.S. adults. Diabetes Care (2007) 2.20
Extracellular superoxide dismutase deficiency exacerbates pressure overload-induced left ventricular hypertrophy and dysfunction. Hypertension (2007) 2.20
Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responses. J Exp Med (2008) 2.04
Functional implications of the localization and activity of acid-sensitive channels in rat peripheral nervous system. Proc Natl Acad Sci U S A (2002) 2.04
The feasibility of using high frequency ultrasound to assess nerve ending neuropathy in patients with diabetic foot. Eur J Radiol (2012) 1.98
Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS. Infect Immun (2006) 1.93
Structure of a protein phosphatase 2A holoenzyme: insights into B55-mediated Tau dephosphorylation. Mol Cell (2008) 1.93
Selective transport of cytokine-induced neutrophil chemoattractant from the lung to the blood facilitates pulmonary neutrophil recruitment. Am J Physiol Lung Cell Mol Physiol (2003) 1.86
Cost-of-illness studies in diabetes mellitus. Pharmacoeconomics (2004) 1.84
Assembly of allosteric macromolecular switches: lessons from PKA. Nat Rev Mol Cell Biol (2012) 1.78
High-resolution genetic mapping with ordered arrays of Saccharomyces cerevisiae deletion mutants. Genetics (2002) 1.78
Computer modeling of diabetes and its complications: a report on the Fifth Mount Hood challenge meeting. Value Health (2013) 1.77
Activation of peroxisome proliferator-activated receptor-γ coactivator 1α ameliorates mitochondrial dysfunction and protects podocytes from aldosterone-induced injury. Kidney Int (2012) 1.75
Cytochrome P450 family member CYP704B2 catalyzes the {omega}-hydroxylation of fatty acids and is required for anther cutin biosynthesis and pollen exine formation in rice. Plant Cell (2010) 1.74
The proximal carboxyl-terminal domains of ADAMTS13 determine substrate specificity and are all required for cleavage of von Willebrand factor. J Biol Chem (2005) 1.73
How should developing countries manage diabetes? CMAJ (2006) 1.69
Interferon action and the double-stranded RNA-dependent enzymes ADAR1 adenosine deaminase and PKR protein kinase. Prog Nucleic Acid Res Mol Biol (2006) 1.62
Focal atrial tachycardia originating from the left atrial appendage: electrocardiographic and electrophysiologic characterization and long-term outcomes of radiofrequency ablation. J Cardiovasc Electrophysiol (2007) 1.62
Heavy metal concentrations in roadside soils and correlation with urban traffic in Beijing, China. J Hazard Mater (2010) 1.61
Mechanism of substrate unfolding and translocation by the regulatory particle of the proteasome from Methanocaldococcus jannaschii. Mol Cell (2009) 1.61
V-ATPase B1-subunit promoter drives expression of EGFP in intercalated cells of kidney, clear cells of epididymis and airway cells of lung in transgenic mice. Am J Physiol Cell Physiol (2005) 1.59
Oxidative stress regulates left ventricular PDE5 expression in the failing heart. Circulation (2010) 1.54
Genetic algorithm with logistic regression for prediction of progression to Alzheimer's disease. BMC Bioinformatics (2014) 1.53
PKA: lessons learned after twenty years. Biochim Biophys Acta (2013) 1.52
An evaluation of cost sharing to finance a diet and physical activity intervention to prevent diabetes. Diabetes Care (2006) 1.51
Predictors of rapid cognitive decline in Alzheimer's disease: results from the Australian imaging, biomarkers and lifestyle (AIBL) study of ageing. Int Psychogeriatr (2011) 1.49
The cost-effectiveness of Welcome to Medicare visual acuity screening and a possible alternative welcome to medicare eye evaluation among persons without diagnosed diabetes mellitus. Arch Ophthalmol (2012) 1.49
PGC-1 alpha regulates expression of myocardial mitochondrial antioxidants and myocardial oxidative stress after chronic systolic overload. Antioxid Redox Signal (2010) 1.48
Notch and BCR signaling synergistically promote the proliferation of Raji B-lymphoma cells. Leuk Res (2008) 1.47
NDRG1, a growth and cancer related gene: regulation of gene expression and function in normal and disease states. Carcinogenesis (2007) 1.47
Suppression of the stem cell antigen-1 response and granulocyte lineage expansion by alcohol during septicemia. Crit Care Med (2011) 1.46
A nationwide community-based lifestyle program could delay or prevent type 2 diabetes cases and save $5.7 billion in 25 years. Health Aff (Millwood) (2012) 1.44
DNA-PKcs, but not TLR9, is required for activation of Akt by CpG-DNA. EMBO J (2005) 1.44
Maintenance of superior learning and memory function in NR2B transgenic mice during ageing. Eur J Neurosci (2007) 1.43
IMU-based online kinematic calibration of robot manipulator. ScientificWorldJournal (2013) 1.42
Cardiac arterial pole alignment is sensitive to FGF8 signaling in the pharynx. Dev Biol (2006) 1.42
Autologous and allogeneic marrow stromal cells are safe and effective for the treatment of acute kidney injury. Stem Cells Dev (2009) 1.41
The effect of chronic binge ethanol consumption on the primary stage of SIV infection in rhesus macaques. Alcohol Clin Exp Res (2003) 1.41
High-risk individuals' willingness to pay for diabetes risk-reduction programs. Diabetes Care (2006) 1.41
Reuse of infected cardiac rhythm management devices in the same patients: a single-center experience. Pacing Clin Electrophysiol (2014) 1.40
Chronic binge ethanol consumption accelerates progression of simian immunodeficiency virus disease. Alcohol Clin Exp Res (2006) 1.40
The extracellular domain determines the kinetics of desensitization in acid-sensitive ion channel 1. J Biol Chem (2003) 1.38
Bioluminescence imaging to monitor the in vivo distribution of administered mesenchymal stem cells in acute kidney injury. Am J Physiol Renal Physiol (2008) 1.36
Knee-loading modality drives molecular transport in mouse femur. Ann Biomed Eng (2006) 1.36
Preparation and properties of a novel drug delivery system with both magnetic and biomolecular targeting. J Mater Sci Mater Med (2008) 1.36
Immobilization of homing peptide on magnetite nanoparticles and its specificity in vitro. J Biomed Mater Res A (2008) 1.35
Role of lipoprotein-associated phospholipase A2 in leukocyte activation and inflammatory responses. Atherosclerosis (2006) 1.34
Lifetime direct medical costs of treating type 2 diabetes and diabetic complications. Am J Prev Med (2013) 1.34
Interferon-γ-induced PD-L1 surface expression on human oral squamous carcinoma via PKD2 signal pathway. Immunobiology (2011) 1.34
CoMn(2)O(4) spinel hierarchical microspheres assembled with porous nanosheets as stable anodes for lithium-ion batteries. Sci Rep (2012) 1.32
Stochasticity, succession, and environmental perturbations in a fluidic ecosystem. Proc Natl Acad Sci U S A (2014) 1.31
Structural factors and mechanisms underlying the improved photodynamic cell killing with silicon phthalocyanine photosensitizers directed to lysosomes versus mitochondria. Photochem Photobiol (2009) 1.31
Endothelial differentiation of adipose-derived stem cells: effects of endothelial cell growth supplement and shear force. J Surg Res (2008) 1.28
Alcohol-induced suppression of lung chemokine production and the host defense response to Streptococcus pneumoniae. Alcohol Clin Exp Res (2003) 1.27
Nrf2-dependent sulfiredoxin-1 expression protects against cigarette smoke-induced oxidative stress in lungs. Free Radic Biol Med (2008) 1.27
The lipopolysaccharide Parkinson's disease animal model: mechanistic studies and drug discovery. Fundam Clin Pharmacol (2008) 1.26
Cost-effectiveness of bariatric surgery for severely obese adults with diabetes. Diabetes Care (2010) 1.25
The effects of interventions on health-related quality of life among persons with diabetes: a systematic review. Med Care (2007) 1.25
pH required to kill Enterococcus faecalis in vitro. J Endod (2004) 1.25
The association of BMI with functional status and self-rated health in US adults. Obesity (Silver Spring) (2008) 1.25
Medical costs associated with type 2 diabetes complications and comorbidities. Am J Manag Care (2013) 1.24
Adenosine A3 receptor deficiency exerts unanticipated protective effects on the pressure-overloaded left ventricle. Circulation (2008) 1.24
Changes in health state utilities with changes in body mass in the Diabetes Prevention Program. Obesity (Silver Spring) (2009) 1.24
Decreased lifespan in the absence of expression of the mitochondrial small heat shock protein Hsp22 in Drosophila. J Biol Chem (2004) 1.22
Improvement of Aspergillus sulphureus endo-beta-1,4-xylanase expression in Pichia pastoris by codon optimization and analysis of the enzymic characterization. Appl Biochem Biotechnol (2009) 1.22
Expression of ABCG2 (BCRP) is regulated by Nrf2 in cancer cells that confers side population and chemoresistance phenotype. Mol Cancer Ther (2010) 1.21
Downregulation of Rap1GAP through epigenetic silencing and loss of heterozygosity promotes invasion and progression of thyroid tumors. Cancer Res (2010) 1.21
Secular trends in diabetes-related preventable hospitalizations in the United States, 1998-2006. Diabetes Care (2009) 1.21
ImmunoGrid, an integrative environment for large-scale simulation of the immune system for vaccine discovery, design and optimization. Brief Bioinform (2009) 1.19
Nickel carcinogenesis: epigenetics and hypoxia signaling. Mutat Res (2005) 1.19
Dimethylarginine dimethylaminohydrolase-1 is the critical enzyme for degrading the cardiovascular risk factor asymmetrical dimethylarginine. Arterioscler Thromb Vasc Biol (2011) 1.19
Chronic alcohol accentuates nutritional, metabolic, and immune alterations during asymptomatic simian immunodeficiency virus infection. Alcohol Clin Exp Res (2006) 1.19
Impact of intensive lifestyle intervention on depression and health-related quality of life in type 2 diabetes: the Look AHEAD Trial. Diabetes Care (2014) 1.19
Effectiveness and cost-effectiveness of diabetes prevention among adherent participants. Am J Manag Care (2013) 1.18
Mechanisms of protein kinase PKR-mediated amplification of beta interferon induction by C protein-deficient measles virus. J Virol (2010) 1.18
Crystal structure of human eIF3k, the first structure of eIF3 subunits. J Biol Chem (2004) 1.18
Expression profiling on soybean leaves reveals integration of ER- and osmotic-stress pathways. BMC Genomics (2007) 1.17
Dimethylarginine dimethylaminohydrolase and endothelial dysfunction in failing hearts. Am J Physiol Heart Circ Physiol (2005) 1.16
ImmunoGrid: towards agent-based simulations of the human immune system at a natural scale. Philos Trans A Math Phys Eng Sci (2010) 1.16
MicroRNAs contribute to the chemoresistance of cisplatin in tongue squamous cell carcinoma lines. Oral Oncol (2010) 1.15
Interleukin-1beta modulates proinflammatory cytokine production in human epithelial cells. Infect Immun (2008) 1.15
VEGF is a mediator of the renoprotective effects of multipotent marrow stromal cells in acute kidney injury. J Cell Mol Med (2008) 1.14
Proteomic analysis of proteins involved in spermiogenesis in mouse. J Proteome Res (2010) 1.13
Aging might increase myocardial ischemia / reperfusion-induced apoptosis in humans and rats. Age (Dordr) (2011) 1.13