1
|
Characterized chondrocyte implantation results in better structural repair when treating symptomatic cartilage defects of the knee in a randomized controlled trial versus microfracture.
|
Am J Sports Med
|
2008
|
3.89
|
2
|
Articular cartilage and biomechanical properties of the long bones in Frzb-knockout mice.
|
Arthritis Rheum
|
2007
|
2.45
|
3
|
Treatment of symptomatic cartilage defects of the knee: characterized chondrocyte implantation results in better clinical outcome at 36 months in a randomized trial compared to microfracture.
|
Am J Sports Med
|
2009
|
2.32
|
4
|
The bone-cartilage unit in osteoarthritis.
|
Nat Rev Rheumatol
|
2010
|
2.21
|
5
|
A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22.
|
Arthritis Rheum
|
2010
|
2.02
|
6
|
Mesenchymal multipotency of adult human periosteal cells demonstrated by single-cell lineage analysis.
|
Arthritis Rheum
|
2006
|
2.01
|
7
|
Skeletal muscle repair by adult human mesenchymal stem cells from synovial membrane.
|
J Cell Biol
|
2003
|
1.99
|
8
|
Osteoarthritis and osteoporosis: clinical and research evidence of inverse relationship.
|
Aging Clin Exp Res
|
2003
|
1.75
|
9
|
Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22.
|
Ann Rheum Dis
|
2010
|
1.75
|
10
|
Modulation of bone morphogenetic protein signaling inhibits the onset and progression of ankylosing enthesitis.
|
J Clin Invest
|
2005
|
1.73
|
11
|
Bone morphogenetic proteins 2 and 6, expressed in arthritic synovium, are regulated by proinflammatory cytokines and differentially modulate fibroblast-like synoviocyte apoptosis.
|
Arthritis Rheum
|
2003
|
1.67
|
12
|
Evidence for uncoupling of inflammation and joint remodeling in a mouse model of spondylarthritis.
|
Arthritis Rheum
|
2007
|
1.61
|
13
|
Tight regulation of wingless-type signaling in the articular cartilage - subchondral bone biomechanical unit: transcriptomics in Frzb-knockout mice.
|
Arthritis Res Ther
|
2012
|
1.52
|
14
|
Engineering vascularized bone: osteogenic and proangiogenic potential of murine periosteal cells.
|
Stem Cells
|
2012
|
1.49
|
15
|
Genome-wide association scan identifies a prostaglandin-endoperoxide synthase 2 variant involved in risk of knee osteoarthritis.
|
Am J Hum Genet
|
2008
|
1.45
|
16
|
Progress in spondylarthritis. Mechanisms of new bone formation in spondyloarthritis.
|
Arthritis Res Ther
|
2009
|
1.42
|
17
|
Failure of in vitro-differentiated mesenchymal stem cells from the synovial membrane to form ectopic stable cartilage in vivo.
|
Arthritis Rheum
|
2004
|
1.34
|
18
|
Five-year outcome of characterized chondrocyte implantation versus microfracture for symptomatic cartilage defects of the knee: early treatment matters.
|
Am J Sports Med
|
2011
|
1.31
|
19
|
Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis.
|
Proc Natl Acad Sci U S A
|
2012
|
1.28
|
20
|
Differentiation potential of human postnatal mesenchymal stem cells, mesoangioblasts, and multipotent adult progenitor cells reflected in their transcriptome and partially influenced by the culture conditions.
|
Stem Cells
|
2011
|
1.28
|
21
|
Developmental engineering: a new paradigm for the design and manufacturing of cell-based products. Part I: from three-dimensional cell growth to biomimetics of in vivo development.
|
Tissue Eng Part B Rev
|
2009
|
1.26
|
22
|
Cartilage repair: past and future--lessons for regenerative medicine.
|
J Cell Mol Med
|
2009
|
1.24
|
23
|
Inhibition of inflammation but not ankylosis by glucocorticoids in mice: further evidence for the entheseal stress hypothesis.
|
Arthritis Res Ther
|
2012
|
1.20
|
24
|
Donor site morbidity after articular cartilage repair procedures: a review.
|
Acta Orthop Belg
|
2010
|
1.14
|
25
|
Quantification of lung fibrosis and emphysema in mice using automated micro-computed tomography.
|
PLoS One
|
2012
|
1.14
|
26
|
Biological aspects of early osteoarthritis.
|
Knee Surg Sports Traumatol Arthrosc
|
2011
|
1.13
|
27
|
Effects of MRI contrast agents on the stem cell phenotype.
|
Cell Transplant
|
2010
|
1.13
|
28
|
Bone morphogenetic protein signaling in joint homeostasis and disease.
|
Cytokine Growth Factor Rev
|
2005
|
1.11
|
29
|
Noggin haploinsufficiency differentially affects tissue responses in destructive and remodeling arthritis.
|
Arthritis Rheum
|
2006
|
1.07
|
30
|
Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development.
|
Development
|
2012
|
1.07
|
31
|
GDF5 deficiency in mice is associated with instability-driven joint damage, gait and subchondral bone changes.
|
Ann Rheum Dis
|
2010
|
1.07
|
32
|
The combined bone forming capacity of human periosteal derived cells and calcium phosphates.
|
Biomaterials
|
2011
|
1.07
|
33
|
A biomarker-based mathematical model to predict bone-forming potency of human synovial and periosteal mesenchymal stem cells.
|
Arthritis Rheum
|
2008
|
1.06
|
34
|
Autologous chondrocyte implantation versus microfracture for knee cartilage injury: a prospective randomized trial, with 2-year follow-up.
|
Knee Surg Sports Traumatol Arthrosc
|
2009
|
1.06
|
35
|
The Noggin null mouse phenotype is strain dependent and haploinsufficiency leads to skeletal defects.
|
Dev Dyn
|
2006
|
1.06
|
36
|
Microenvironment and phenotypic stability specify tissue formation by human articular cartilage-derived cells in vivo.
|
Exp Cell Res
|
2003
|
1.04
|
37
|
Bone regeneration: stem cell therapies and clinical studies in orthopaedics and traumatology.
|
J Cell Mol Med
|
2011
|
1.03
|
38
|
Treatment of early rheumatoid arthritis: a randomized magnetic resonance imaging study comparing the effects of methotrexate alone, methotrexate in combination with infliximab, and methotrexate in combination with intravenous pulse methylprednisolone.
|
Arthritis Rheum
|
2007
|
1.01
|
39
|
Expanded phenotypically stable chondrocytes persist in the repair tissue and contribute to cartilage matrix formation and structural integration in a goat model of autologous chondrocyte implantation.
|
J Orthop Res
|
2003
|
1.01
|
40
|
Xenopus SMOC-1 Inhibits bone morphogenetic protein signaling downstream of receptor binding and is essential for postgastrulation development in Xenopus.
|
J Biol Chem
|
2009
|
1.00
|
41
|
Probing the osteoinductive effect of calcium phosphate by using an in vitro biomimetic model.
|
Tissue Eng Part A
|
2011
|
0.98
|
42
|
Species specificity of ectopic bone formation using periosteum-derived mesenchymal progenitor cells.
|
Tissue Eng
|
2006
|
0.98
|
43
|
Mechanisms of ectopic bone formation by human osteoprogenitor cells on CaP biomaterial carriers.
|
Biomaterials
|
2012
|
0.95
|
44
|
Gait characteristics and lower limb muscle strength in women with early and established knee osteoarthritis.
|
Clin Biomech (Bristol, Avon)
|
2012
|
0.93
|
45
|
Dependence on interferon-gamma for the spontaneous occurrence of arthritis in DBA/1 mice.
|
Arthritis Rheum
|
2003
|
0.92
|
46
|
Noggin null allele mice exhibit a microform of holoprosencephaly.
|
Hum Mol Genet
|
2011
|
0.92
|
47
|
18F-FDG labeling of mesenchymal stem cells and multipotent adult progenitor cells for PET imaging: effects on ultrastructure and differentiation capacity.
|
J Nucl Med
|
2013
|
0.91
|
48
|
Ectopic bone formation by 3D porous calcium phosphate-Ti6Al4V hybrids produced by perfusion electrodeposition.
|
Biomaterials
|
2012
|
0.90
|
49
|
Proprioceptive accuracy in women with early and established knee osteoarthritis and its relation to functional ability, postural control, and muscle strength.
|
Clin Rheumatol
|
2013
|
0.89
|
50
|
Expansion of murine periosteal progenitor cells with fibroblast growth factor 2 reveals an intrinsic endochondral ossification program mediated by bone morphogenetic protein 2.
|
Stem Cells
|
2014
|
0.88
|
51
|
Identifying postmenopausal women with osteoporosis by calcaneal ultrasound, metacarpal digital X-ray radiogrammetry and phalangeal radiographic absorptiometry: a comparative study.
|
Osteoporos Int
|
2004
|
0.88
|
52
|
Are current available therapies disease-modifying in spondyloarthritis?
|
Best Pract Res Clin Rheumatol
|
2010
|
0.87
|
53
|
Structure of NPP1, an ectonucleotide pyrophosphatase/phosphodiesterase involved in tissue calcification.
|
Structure
|
2012
|
0.87
|
54
|
Validation of a PicoGreen-based DNA quantification integrated in an RNA extraction method for two-dimensional and three-dimensional cell cultures.
|
Tissue Eng Part C Methods
|
2012
|
0.86
|
55
|
Enhancement of osteogenic gene expression for the differentiation of human periosteal derived cells.
|
Stem Cell Res
|
2011
|
0.86
|
56
|
Characterization and optimization of cell seeding in scaffolds by factorial design: quality by design approach for skeletal tissue engineering.
|
Tissue Eng Part C Methods
|
2011
|
0.86
|
57
|
Mapping calcium phosphate activated gene networks as a strategy for targeted osteoinduction of human progenitors.
|
Biomaterials
|
2013
|
0.86
|
58
|
White paper on how to go forward with cell-based advanced therapies in Europe.
|
Tissue Eng Part A
|
2014
|
0.86
|
59
|
Bone morphogenetic proteins in destructive and remodeling arthritis.
|
Arthritis Res Ther
|
2007
|
0.86
|
60
|
Physical activity levels after characterized chondrocyte implantation versus microfracture in the knee and the relationship to objective functional outcome with 2-year follow-up.
|
Am J Sports Med
|
2009
|
0.86
|
61
|
Mechanisms of pathologic new bone formation.
|
Curr Rheumatol Rep
|
2006
|
0.86
|
62
|
A semi-autonomous model of endochondral ossification for developmental tissue engineering.
|
Tissue Eng Part A
|
2012
|
0.86
|
63
|
Functional effects of susceptibility genes in osteoarthritis.
|
Discov Med
|
2011
|
0.85
|
64
|
Flow cytometric characterization of freshly isolated and culture expanded human synovial cell populations in patients with chronic arthritis.
|
Arthritis Res Ther
|
2010
|
0.85
|
65
|
An N-terminal G11A mutation in HOXD13 causes synpolydactyly and interferes with Gli3R function during limb pre-patterning.
|
Hum Mol Genet
|
2012
|
0.85
|
66
|
Blocking p38 signalling inhibits chondrogenesis in vitro but not ankylosis in a model of ankylosing spondylitis in vivo.
|
Ann Rheum Dis
|
2011
|
0.84
|
67
|
Developmental engineering: a new paradigm for the design and manufacturing of cell-based products. Part II: from genes to networks: tissue engineering from the viewpoint of systems biology and network science.
|
Tissue Eng Part B Rev
|
2009
|
0.84
|
68
|
Process quality engineering for bioreactor-driven manufacturing of tissue-engineered constructs for bone regeneration.
|
Tissue Eng Part C Methods
|
2013
|
0.83
|
69
|
Dynamic activation of bone morphogenetic protein signaling in collagen-induced arthritis supports their role in joint homeostasis and disease.
|
Arthritis Res Ther
|
2008
|
0.83
|
70
|
Spatial optimization in perfusion bioreactors improves bone tissue-engineered construct quality attributes.
|
Biotechnol Bioeng
|
2014
|
0.83
|
71
|
Variation at the ANP32A gene is associated with risk of hip osteoarthritis in women.
|
Arthritis Rheum
|
2009
|
0.82
|
72
|
Genetic deletion of low-density lipoprotein receptor-related protein 5 increases cartilage degradation in instability-induced osteoarthritis.
|
Rheumatology (Oxford)
|
2012
|
0.82
|
73
|
Implementing one standardized rehabilitation protocol following autologous chondrocyte implantation or microfracture in the knee results in comparable physical therapy management.
|
Physiother Theory Pract
|
2010
|
0.82
|
74
|
Critical illness-related bone loss is associated with osteoclastic and angiogenic abnormalities.
|
J Bone Miner Res
|
2012
|
0.81
|
75
|
Activation of cartilage-derived morphogenetic protein-1 in torn rotator cuff.
|
Clin Orthop Relat Res
|
2002
|
0.81
|
76
|
Three-dimensional characterization of tissue-engineered constructs by contrast-enhanced nanofocus computed tomography.
|
Tissue Eng Part C Methods
|
2013
|
0.81
|
77
|
Zfhx1a and Zfhx1b mRNAs have non-overlapping expression domains during chick and mouse midgestation limb development.
|
Gene Expr Patterns
|
2003
|
0.80
|
78
|
delta-EF1 is a negative regulator of Ihh in the developing growth plate.
|
J Cell Biol
|
2009
|
0.80
|
79
|
High inter-specimen variability of baseline data for the tibio-talar contact area.
|
Clin Biomech (Bristol, Avon)
|
2008
|
0.80
|
80
|
Characterization of Frzb-Cre transgenic mouse.
|
Genesis
|
2004
|
0.79
|
81
|
Quantitative screening of engineered implants in a long bone defect model in rabbits.
|
Tissue Eng Part C Methods
|
2008
|
0.79
|
82
|
Osteoimmunology: Wnt antagonists: for better or worse?
|
Nat Rev Rheumatol
|
2009
|
0.79
|
83
|
Relating the chondrocyte gene network to growth plate morphology: from genes to phenotype.
|
PLoS One
|
2012
|
0.79
|
84
|
Bone morphogenetic protein signaling and arthritis.
|
Cytokine Growth Factor Rev
|
2009
|
0.79
|
85
|
Skeletal tissue regeneration: where can hydrogels play a role?
|
Int Orthop
|
2014
|
0.78
|
86
|
Smoc2 modulates embryonic myelopoiesis during zebrafish development.
|
Dev Dyn
|
2014
|
0.78
|
87
|
Destructive dural ectasia of dorsal and lumbar spine with cauda equina syndrome in a patient with ankylosing spondylitis.
|
Open Rheumatol J
|
2010
|
0.78
|
88
|
Weak associations between structural changes on MRI and symptoms, function and muscle strength in relation to knee osteoarthritis.
|
Knee Surg Sports Traumatol Arthrosc
|
2013
|
0.78
|
89
|
Characterized chondrocyte implantation in the patellofemoral joint: an up to 4-year follow-up of a prospective cohort of 38 patients.
|
Am J Sports Med
|
2012
|
0.78
|
90
|
Bone augmentation with autologous periosteal cells and two different calcium phosphate scaffolds under an occlusive titanium barrier: an experimental study in rabbits.
|
J Periodontol
|
2008
|
0.78
|
91
|
The posteromedial rim of the talar dome as the site for harvesting cartilage in the ankle: an anatomic study.
|
Arthroscopy
|
2006
|
0.77
|
92
|
Sox9 reprogrammed dermal fibroblasts undergo hypertrophic differentiation in vitro and trigger endochondral ossification in vivo.
|
Cell Reprogram
|
2014
|
0.77
|
93
|
Activated fibrocytes: circulating cells that populate the arthritic synovium?
|
Rheumatology (Oxford)
|
2009
|
0.76
|
94
|
Modularity in developmental biology and artificial organs: a missing concept in tissue engineering.
|
Artif Organs
|
2011
|
0.76
|
95
|
Humanized culture of periosteal progenitors in allogeneic serum enhances osteogenic differentiation and in vivo bone formation.
|
Stem Cells Transl Med
|
2013
|
0.76
|
96
|
Multi-level factorial analysis of Ca2+/Pi supplementation as bio-instructive media for in vitro biomimetic engineering of three-dimensional osteogenic hybrids.
|
Tissue Eng Part C Methods
|
2011
|
0.76
|
97
|
Mechanical loading reduces inflammation-induced human osteocyte-to-osteoclast communication.
|
Calcif Tissue Int
|
2015
|
0.76
|
98
|
Osteoarthritis, a disease bridging development and regeneration.
|
Bonekey Rep
|
2012
|
0.76
|
99
|
Perfusion electrodeposition of calcium phosphate on additive manufactured titanium scaffolds for bone engineering.
|
Acta Biomater
|
2011
|
0.75
|
100
|
Do Psychosocial Factors Predict Muscle Strength, Pain, or Physical Performance in Patients With Knee Osteoarthritis?
|
J Clin Rheumatol
|
2017
|
0.75
|