Frank P Luyten

Author PubWeight™ 104.63‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Characterized chondrocyte implantation results in better structural repair when treating symptomatic cartilage defects of the knee in a randomized controlled trial versus microfracture. Am J Sports Med 2008 3.89
2 Articular cartilage and biomechanical properties of the long bones in Frzb-knockout mice. Arthritis Rheum 2007 2.45
3 Treatment of symptomatic cartilage defects of the knee: characterized chondrocyte implantation results in better clinical outcome at 36 months in a randomized trial compared to microfracture. Am J Sports Med 2009 2.32
4 The bone-cartilage unit in osteoarthritis. Nat Rev Rheumatol 2010 2.21
5 A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22. Arthritis Rheum 2010 2.02
6 Mesenchymal multipotency of adult human periosteal cells demonstrated by single-cell lineage analysis. Arthritis Rheum 2006 2.01
7 Skeletal muscle repair by adult human mesenchymal stem cells from synovial membrane. J Cell Biol 2003 1.99
8 Osteoarthritis and osteoporosis: clinical and research evidence of inverse relationship. Aging Clin Exp Res 2003 1.75
9 Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22. Ann Rheum Dis 2010 1.75
10 Modulation of bone morphogenetic protein signaling inhibits the onset and progression of ankylosing enthesitis. J Clin Invest 2005 1.73
11 Bone morphogenetic proteins 2 and 6, expressed in arthritic synovium, are regulated by proinflammatory cytokines and differentially modulate fibroblast-like synoviocyte apoptosis. Arthritis Rheum 2003 1.67
12 Evidence for uncoupling of inflammation and joint remodeling in a mouse model of spondylarthritis. Arthritis Rheum 2007 1.61
13 Tight regulation of wingless-type signaling in the articular cartilage - subchondral bone biomechanical unit: transcriptomics in Frzb-knockout mice. Arthritis Res Ther 2012 1.52
14 Engineering vascularized bone: osteogenic and proangiogenic potential of murine periosteal cells. Stem Cells 2012 1.49
15 Genome-wide association scan identifies a prostaglandin-endoperoxide synthase 2 variant involved in risk of knee osteoarthritis. Am J Hum Genet 2008 1.45
16 Progress in spondylarthritis. Mechanisms of new bone formation in spondyloarthritis. Arthritis Res Ther 2009 1.42
17 Failure of in vitro-differentiated mesenchymal stem cells from the synovial membrane to form ectopic stable cartilage in vivo. Arthritis Rheum 2004 1.34
18 Five-year outcome of characterized chondrocyte implantation versus microfracture for symptomatic cartilage defects of the knee: early treatment matters. Am J Sports Med 2011 1.31
19 Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis. Proc Natl Acad Sci U S A 2012 1.28
20 Differentiation potential of human postnatal mesenchymal stem cells, mesoangioblasts, and multipotent adult progenitor cells reflected in their transcriptome and partially influenced by the culture conditions. Stem Cells 2011 1.28
21 Developmental engineering: a new paradigm for the design and manufacturing of cell-based products. Part I: from three-dimensional cell growth to biomimetics of in vivo development. Tissue Eng Part B Rev 2009 1.26
22 Cartilage repair: past and future--lessons for regenerative medicine. J Cell Mol Med 2009 1.24
23 Inhibition of inflammation but not ankylosis by glucocorticoids in mice: further evidence for the entheseal stress hypothesis. Arthritis Res Ther 2012 1.20
24 Donor site morbidity after articular cartilage repair procedures: a review. Acta Orthop Belg 2010 1.14
25 Quantification of lung fibrosis and emphysema in mice using automated micro-computed tomography. PLoS One 2012 1.14
26 Biological aspects of early osteoarthritis. Knee Surg Sports Traumatol Arthrosc 2011 1.13
27 Effects of MRI contrast agents on the stem cell phenotype. Cell Transplant 2010 1.13
28 Bone morphogenetic protein signaling in joint homeostasis and disease. Cytokine Growth Factor Rev 2005 1.11
29 Noggin haploinsufficiency differentially affects tissue responses in destructive and remodeling arthritis. Arthritis Rheum 2006 1.07
30 Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development. Development 2012 1.07
31 GDF5 deficiency in mice is associated with instability-driven joint damage, gait and subchondral bone changes. Ann Rheum Dis 2010 1.07
32 The combined bone forming capacity of human periosteal derived cells and calcium phosphates. Biomaterials 2011 1.07
33 A biomarker-based mathematical model to predict bone-forming potency of human synovial and periosteal mesenchymal stem cells. Arthritis Rheum 2008 1.06
34 Autologous chondrocyte implantation versus microfracture for knee cartilage injury: a prospective randomized trial, with 2-year follow-up. Knee Surg Sports Traumatol Arthrosc 2009 1.06
35 The Noggin null mouse phenotype is strain dependent and haploinsufficiency leads to skeletal defects. Dev Dyn 2006 1.06
36 Microenvironment and phenotypic stability specify tissue formation by human articular cartilage-derived cells in vivo. Exp Cell Res 2003 1.04
37 Bone regeneration: stem cell therapies and clinical studies in orthopaedics and traumatology. J Cell Mol Med 2011 1.03
38 Treatment of early rheumatoid arthritis: a randomized magnetic resonance imaging study comparing the effects of methotrexate alone, methotrexate in combination with infliximab, and methotrexate in combination with intravenous pulse methylprednisolone. Arthritis Rheum 2007 1.01
39 Expanded phenotypically stable chondrocytes persist in the repair tissue and contribute to cartilage matrix formation and structural integration in a goat model of autologous chondrocyte implantation. J Orthop Res 2003 1.01
40 Xenopus SMOC-1 Inhibits bone morphogenetic protein signaling downstream of receptor binding and is essential for postgastrulation development in Xenopus. J Biol Chem 2009 1.00
41 Probing the osteoinductive effect of calcium phosphate by using an in vitro biomimetic model. Tissue Eng Part A 2011 0.98
42 Species specificity of ectopic bone formation using periosteum-derived mesenchymal progenitor cells. Tissue Eng 2006 0.98
43 Mechanisms of ectopic bone formation by human osteoprogenitor cells on CaP biomaterial carriers. Biomaterials 2012 0.95
44 Gait characteristics and lower limb muscle strength in women with early and established knee osteoarthritis. Clin Biomech (Bristol, Avon) 2012 0.93
45 Dependence on interferon-gamma for the spontaneous occurrence of arthritis in DBA/1 mice. Arthritis Rheum 2003 0.92
46 Noggin null allele mice exhibit a microform of holoprosencephaly. Hum Mol Genet 2011 0.92
47 18F-FDG labeling of mesenchymal stem cells and multipotent adult progenitor cells for PET imaging: effects on ultrastructure and differentiation capacity. J Nucl Med 2013 0.91
48 Ectopic bone formation by 3D porous calcium phosphate-Ti6Al4V hybrids produced by perfusion electrodeposition. Biomaterials 2012 0.90
49 Proprioceptive accuracy in women with early and established knee osteoarthritis and its relation to functional ability, postural control, and muscle strength. Clin Rheumatol 2013 0.89
50 Expansion of murine periosteal progenitor cells with fibroblast growth factor 2 reveals an intrinsic endochondral ossification program mediated by bone morphogenetic protein 2. Stem Cells 2014 0.88
51 Identifying postmenopausal women with osteoporosis by calcaneal ultrasound, metacarpal digital X-ray radiogrammetry and phalangeal radiographic absorptiometry: a comparative study. Osteoporos Int 2004 0.88
52 Are current available therapies disease-modifying in spondyloarthritis? Best Pract Res Clin Rheumatol 2010 0.87
53 Structure of NPP1, an ectonucleotide pyrophosphatase/phosphodiesterase involved in tissue calcification. Structure 2012 0.87
54 Validation of a PicoGreen-based DNA quantification integrated in an RNA extraction method for two-dimensional and three-dimensional cell cultures. Tissue Eng Part C Methods 2012 0.86
55 Enhancement of osteogenic gene expression for the differentiation of human periosteal derived cells. Stem Cell Res 2011 0.86
56 Characterization and optimization of cell seeding in scaffolds by factorial design: quality by design approach for skeletal tissue engineering. Tissue Eng Part C Methods 2011 0.86
57 Mapping calcium phosphate activated gene networks as a strategy for targeted osteoinduction of human progenitors. Biomaterials 2013 0.86
58 White paper on how to go forward with cell-based advanced therapies in Europe. Tissue Eng Part A 2014 0.86
59 Bone morphogenetic proteins in destructive and remodeling arthritis. Arthritis Res Ther 2007 0.86
60 Physical activity levels after characterized chondrocyte implantation versus microfracture in the knee and the relationship to objective functional outcome with 2-year follow-up. Am J Sports Med 2009 0.86
61 Mechanisms of pathologic new bone formation. Curr Rheumatol Rep 2006 0.86
62 A semi-autonomous model of endochondral ossification for developmental tissue engineering. Tissue Eng Part A 2012 0.86
63 Functional effects of susceptibility genes in osteoarthritis. Discov Med 2011 0.85
64 Flow cytometric characterization of freshly isolated and culture expanded human synovial cell populations in patients with chronic arthritis. Arthritis Res Ther 2010 0.85
65 An N-terminal G11A mutation in HOXD13 causes synpolydactyly and interferes with Gli3R function during limb pre-patterning. Hum Mol Genet 2012 0.85
66 Blocking p38 signalling inhibits chondrogenesis in vitro but not ankylosis in a model of ankylosing spondylitis in vivo. Ann Rheum Dis 2011 0.84
67 Developmental engineering: a new paradigm for the design and manufacturing of cell-based products. Part II: from genes to networks: tissue engineering from the viewpoint of systems biology and network science. Tissue Eng Part B Rev 2009 0.84
68 Process quality engineering for bioreactor-driven manufacturing of tissue-engineered constructs for bone regeneration. Tissue Eng Part C Methods 2013 0.83
69 Dynamic activation of bone morphogenetic protein signaling in collagen-induced arthritis supports their role in joint homeostasis and disease. Arthritis Res Ther 2008 0.83
70 Spatial optimization in perfusion bioreactors improves bone tissue-engineered construct quality attributes. Biotechnol Bioeng 2014 0.83
71 Variation at the ANP32A gene is associated with risk of hip osteoarthritis in women. Arthritis Rheum 2009 0.82
72 Genetic deletion of low-density lipoprotein receptor-related protein 5 increases cartilage degradation in instability-induced osteoarthritis. Rheumatology (Oxford) 2012 0.82
73 Implementing one standardized rehabilitation protocol following autologous chondrocyte implantation or microfracture in the knee results in comparable physical therapy management. Physiother Theory Pract 2010 0.82
74 Critical illness-related bone loss is associated with osteoclastic and angiogenic abnormalities. J Bone Miner Res 2012 0.81
75 Activation of cartilage-derived morphogenetic protein-1 in torn rotator cuff. Clin Orthop Relat Res 2002 0.81
76 Three-dimensional characterization of tissue-engineered constructs by contrast-enhanced nanofocus computed tomography. Tissue Eng Part C Methods 2013 0.81
77 Zfhx1a and Zfhx1b mRNAs have non-overlapping expression domains during chick and mouse midgestation limb development. Gene Expr Patterns 2003 0.80
78 delta-EF1 is a negative regulator of Ihh in the developing growth plate. J Cell Biol 2009 0.80
79 High inter-specimen variability of baseline data for the tibio-talar contact area. Clin Biomech (Bristol, Avon) 2008 0.80
80 Characterization of Frzb-Cre transgenic mouse. Genesis 2004 0.79
81 Quantitative screening of engineered implants in a long bone defect model in rabbits. Tissue Eng Part C Methods 2008 0.79
82 Osteoimmunology: Wnt antagonists: for better or worse? Nat Rev Rheumatol 2009 0.79
83 Relating the chondrocyte gene network to growth plate morphology: from genes to phenotype. PLoS One 2012 0.79
84 Bone morphogenetic protein signaling and arthritis. Cytokine Growth Factor Rev 2009 0.79
85 Skeletal tissue regeneration: where can hydrogels play a role? Int Orthop 2014 0.78
86 Smoc2 modulates embryonic myelopoiesis during zebrafish development. Dev Dyn 2014 0.78
87 Destructive dural ectasia of dorsal and lumbar spine with cauda equina syndrome in a patient with ankylosing spondylitis. Open Rheumatol J 2010 0.78
88 Weak associations between structural changes on MRI and symptoms, function and muscle strength in relation to knee osteoarthritis. Knee Surg Sports Traumatol Arthrosc 2013 0.78
89 Characterized chondrocyte implantation in the patellofemoral joint: an up to 4-year follow-up of a prospective cohort of 38 patients. Am J Sports Med 2012 0.78
90 Bone augmentation with autologous periosteal cells and two different calcium phosphate scaffolds under an occlusive titanium barrier: an experimental study in rabbits. J Periodontol 2008 0.78
91 The posteromedial rim of the talar dome as the site for harvesting cartilage in the ankle: an anatomic study. Arthroscopy 2006 0.77
92 Sox9 reprogrammed dermal fibroblasts undergo hypertrophic differentiation in vitro and trigger endochondral ossification in vivo. Cell Reprogram 2014 0.77
93 Activated fibrocytes: circulating cells that populate the arthritic synovium? Rheumatology (Oxford) 2009 0.76
94 Modularity in developmental biology and artificial organs: a missing concept in tissue engineering. Artif Organs 2011 0.76
95 Humanized culture of periosteal progenitors in allogeneic serum enhances osteogenic differentiation and in vivo bone formation. Stem Cells Transl Med 2013 0.76
96 Multi-level factorial analysis of Ca2+/Pi supplementation as bio-instructive media for in vitro biomimetic engineering of three-dimensional osteogenic hybrids. Tissue Eng Part C Methods 2011 0.76
97 Mechanical loading reduces inflammation-induced human osteocyte-to-osteoclast communication. Calcif Tissue Int 2015 0.76
98 Osteoarthritis, a disease bridging development and regeneration. Bonekey Rep 2012 0.76
99 Perfusion electrodeposition of calcium phosphate on additive manufactured titanium scaffolds for bone engineering. Acta Biomater 2011 0.75
100 Do Psychosocial Factors Predict Muscle Strength, Pain, or Physical Performance in Patients With Knee Osteoarthritis? J Clin Rheumatol 2017 0.75