Published in J Bone Miner Res on July 01, 2012
Critical illness-induced bone loss is related to deficient autophagy and histone hypomethylation. Intensive Care Med Exp (2015) 0.82
The association between critical illness and changes in bone turnover in adults: a systematic review. Osteoporos Int (2014) 0.80
Evaluation of Bone Metabolism in Critically Ill Patients Using CTx and PINP. Biomed Res Int (2016) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Early versus late parenteral nutrition in critically ill adults. N Engl J Med (2011) 12.10
Intensive insulin therapy for patients in paediatric intensive care: a prospective, randomised controlled study. Lancet (2009) 6.44
Reduced cortisol metabolism during critical illness. N Engl J Med (2013) 6.01
ESPEN Guidelines on Parenteral Nutrition: intensive care. Clin Nutr (2009) 4.11
Serum potassium levels and mortality in acute myocardial infarction. JAMA (2012) 4.09
Nutrition in the acute phase of critical illness. N Engl J Med (2014) 4.02
Management of hyperglycemia in hospitalized patients in non-critical care setting: an endocrine society clinical practice guideline. J Clin Endocrinol Metab (2012) 4.02
Characterized chondrocyte implantation results in better structural repair when treating symptomatic cartilage defects of the knee in a randomized controlled trial versus microfracture. Am J Sports Med (2008) 3.89
Tight blood glucose control with insulin in the ICU: facts and controversies. Chest (2007) 3.79
Neurocognitive development of children 4 years after critical illness and treatment with tight glucose control: a randomized controlled trial. JAMA (2012) 3.16
Dynamic characteristics of blood glucose time series during the course of critical illness: effects of intensive insulin therapy and relative association with mortality. Crit Care Med (2010) 3.16
Concern Guidelines for pre-operative cardiac risk assessment and perioperative cardiac management in non-cardiac surgery. Eur Heart J (2009) 3.14
Acute upregulation of an NKG2D ligand promotes rapid reorganization of a local immune compartment with pleiotropic effects on carcinogenesis. Nat Immunol (2008) 3.14
CD27 is a thymic determinant of the balance between interferon-gamma- and interleukin 17-producing gammadelta T cell subsets. Nat Immunol (2009) 3.00
Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance. Nat Immunol (2005) 2.94
Impact of early parenteral nutrition on muscle and adipose tissue compartments during critical illness. Crit Care Med (2013) 2.81
Acute outcomes and 1-year mortality of intensive care unit-acquired weakness. A cohort study and propensity-matched analysis. Am J Respir Crit Care Med (2014) 2.68
Amino acid concentrations in critically ill children following cardiac surgery*. Pediatr Crit Care Med (2014) 2.65
Articular cartilage and biomechanical properties of the long bones in Frzb-knockout mice. Arthritis Rheum (2007) 2.45
Selection of the cutaneous intraepithelial gammadelta+ T cell repertoire by a thymic stromal determinant. Nat Immunol (2006) 2.43
Treatment of symptomatic cartilage defects of the knee: characterized chondrocyte implantation results in better clinical outcome at 36 months in a randomized trial compared to microfracture. Am J Sports Med (2009) 2.32
Impact of intensive insulin therapy on neuromuscular complications and ventilator dependency in the medical intensive care unit. Am J Respir Crit Care Med (2006) 2.22
The bone-cartilage unit in osteoarthritis. Nat Rev Rheumatol (2010) 2.21
Cytomegalovirus serostatus and outcome in nonimmunocompromised critically ill patients. Crit Care Med (2012) 2.14
Intensive insulin therapy protects the endothelium of critically ill patients. J Clin Invest (2005) 2.11
Polymorphisms in innate immunity genes predispose to bacteremia and death in the medical intensive care unit. Crit Care Med (2009) 2.10
Pressure autoregulation monitoring and cerebral perfusion pressure target recommendation in patients with severe traumatic brain injury based on minute-by-minute monitoring data. J Neurosurg (2014) 2.04
A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22. Arthritis Rheum (2010) 2.02
Mesenchymal multipotency of adult human periosteal cells demonstrated by single-cell lineage analysis. Arthritis Rheum (2006) 2.01
Skeletal muscle repair by adult human mesenchymal stem cells from synovial membrane. J Cell Biol (2003) 1.99
Intensive insulin therapy exerts antiinflammatory effects in critically ill patients and counteracts the adverse effect of low mannose-binding lectin levels. J Clin Endocrinol Metab (2003) 1.93
Insufficient autophagy contributes to mitochondrial dysfunction, organ failure, and adverse outcome in an animal model of critical illness. Crit Care Med (2013) 1.78
Protection of hepatocyte mitochondrial ultrastructure and function by strict blood glucose control with insulin in critically ill patients. Lancet (2005) 1.78
Early events in the thymus affect the balance of effector and regulatory T cells. Nature (2006) 1.78
Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22. Ann Rheum Dis (2010) 1.75
Osteoarthritis and osteoporosis: clinical and research evidence of inverse relationship. Aging Clin Exp Res (2003) 1.75
Modulation of bone morphogenetic protein signaling inhibits the onset and progression of ankylosing enthesitis. J Clin Invest (2005) 1.73
Clinical review: Consensus recommendations on measurement of blood glucose and reporting glycemic control in critically ill adults. Crit Care (2013) 1.72
Clinical review: Critical illness polyneuropathy and myopathy. Crit Care (2008) 1.69
Tight blood glucose control is renoprotective in critically ill patients. J Am Soc Nephrol (2008) 1.67
Bone morphogenetic proteins 2 and 6, expressed in arthritic synovium, are regulated by proinflammatory cytokines and differentially modulate fibroblast-like synoviocyte apoptosis. Arthritis Rheum (2003) 1.67
Evidence for uncoupling of inflammation and joint remodeling in a mouse model of spondylarthritis. Arthritis Rheum (2007) 1.61
Cortisol response to critical illness: effect of intensive insulin therapy. J Clin Endocrinol Metab (2006) 1.60
Tight glycemic control protects the myocardium and reduces inflammation in neonatal heart surgery. Ann Thorac Surg (2010) 1.59
American College of Endocrinology position statement on inpatient diabetes and metabolic control. Endocr Pract (2004) 1.59
Novel methods to predict increased intracranial pressure during intensive care and long-term neurologic outcome after traumatic brain injury: development and validation in a multicenter dataset. Crit Care Med (2013) 1.58
Modulation of asymmetric dimethylarginine in critically ill patients receiving intensive insulin treatment: a possible explanation of reduced morbidity and mortality? Crit Care Med (2005) 1.58
Muscle atrophy and preferential loss of myosin in prolonged critically ill patients. Crit Care Med (2012) 1.57
Association between elevated blood glucose and outcome in acute heart failure: results from an international observational cohort. J Am Coll Cardiol (2013) 1.55
Tight regulation of wingless-type signaling in the articular cartilage - subchondral bone biomechanical unit: transcriptomics in Frzb-knockout mice. Arthritis Res Ther (2012) 1.52
Reducing mortality in sepsis: new directions. Crit Care (2002) 1.52
The distinct contributions of murine T cell receptor (TCR)gammadelta+ and TCRalphabeta+ T cells to different stages of chemically induced skin cancer. J Exp Med (2003) 1.51
Reduced activation and increased inactivation of thyroid hormone in tissues of critically ill patients. J Clin Endocrinol Metab (2003) 1.50
Regulation of the somatotropic axis by intensive insulin therapy during protracted critical illness. J Clin Endocrinol Metab (2004) 1.50
Engineering vascularized bone: osteogenic and proangiogenic potential of murine periosteal cells. Stem Cells (2012) 1.49
Effect of insulin therapy on coagulation and fibrinolysis in medical intensive care patients. Crit Care Med (2008) 1.49
American College of Endocrinology position statement on inpatient diabetes and metabolic control. Endocr Pract (2004) 1.47
Genome-wide association scan identifies a prostaglandin-endoperoxide synthase 2 variant involved in risk of knee osteoarthritis. Am J Hum Genet (2008) 1.45
Visualizing the pressure and time burden of intracranial hypertension in adult and paediatric traumatic brain injury. Intensive Care Med (2015) 1.44
Neuropathological Correlates of Hyperglycemia During Prolonged Polymicrobial Sepsis in Mice. Shock (2015) 1.43
Progress in spondylarthritis. Mechanisms of new bone formation in spondyloarthritis. Arthritis Res Ther (2009) 1.42
Withholding parenteral nutrition during critical illness increases plasma bilirubin but lowers the incidence of biliary sludge. Hepatology (2014) 1.40
Tight Glycemic Control in Critically Ill Children. N Engl J Med (2017) 1.39
Strict blood glucose control with insulin during intensive care after cardiac surgery: impact on 4-years survival, dependency on medical care, and quality-of-life. Eur Heart J (2006) 1.39
Worldwide Survey of Nutritional Practices in PICUs. Pediatr Crit Care Med (2016) 1.39
Serum 3,3',5'-triiodothyronine (rT3) and 3,5,3'-triiodothyronine/rT3 are prognostic markers in critically ill patients and are associated with postmortem tissue deiodinase activities. J Clin Endocrinol Metab (2005) 1.37
Survival benefits of intensive insulin therapy in critical illness: impact of maintaining normoglycemia versus glycemia-independent actions of insulin. Diabetes (2006) 1.34
Failure of in vitro-differentiated mesenchymal stem cells from the synovial membrane to form ectopic stable cartilage in vivo. Arthritis Rheum (2004) 1.34
Role of disease and macronutrient dose in the randomized controlled EPaNIC trial: a post hoc analysis. Am J Respir Crit Care Med (2012) 1.34
Five-year outcome of characterized chondrocyte implantation versus microfracture for symptomatic cartilage defects of the knee: early treatment matters. Am J Sports Med (2011) 1.31
Contribution of circulating lipids to the improved outcome of critical illness by glycemic control with intensive insulin therapy. J Clin Endocrinol Metab (2004) 1.31
Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis. Proc Natl Acad Sci U S A (2012) 1.28
Insufficient activation of autophagy allows cellular damage to accumulate in critically ill patients. J Clin Endocrinol Metab (2011) 1.27
Developmental engineering: a new paradigm for the design and manufacturing of cell-based products. Part I: from three-dimensional cell growth to biomimetics of in vivo development. Tissue Eng Part B Rev (2009) 1.26
Metabolic, endocrine, and immune effects of stress hyperglycemia in a rabbit model of prolonged critical illness. Endocrinology (2003) 1.25
Cartilage repair: past and future--lessons for regenerative medicine. J Cell Mol Med (2009) 1.24
Langerhans cells facilitate epithelial DNA damage and squamous cell carcinoma. Science (2012) 1.24
Inhibition of inflammation but not ankylosis by glucocorticoids in mice: further evidence for the entheseal stress hypothesis. Arthritis Res Ther (2012) 1.20
The altered adrenal axis and treatment with glucocorticoids during critical illness. Nat Clin Pract Endocrinol Metab (2008) 1.20
Early parenteral nutrition evokes a phenotype of autophagy deficiency in liver and skeletal muscle of critically ill rabbits. Endocrinology (2012) 1.18
Intensive insulin therapy: enhanced Model Predictive Control algorithm versus standard care. Intensive Care Med (2008) 1.18
Glycemic penalty index for adequately assessing and comparing different blood glucose control algorithms. Crit Care (2008) 1.17
Interventions for preventing critical illness polyneuropathy and critical illness myopathy. Cochrane Database Syst Rev (2009) 1.16
Effect of intensive insulin therapy on insulin sensitivity in the critically ill. J Clin Endocrinol Metab (2007) 1.16
Donor site morbidity after articular cartilage repair procedures: a review. Acta Orthop Belg (2010) 1.14
Quantification of lung fibrosis and emphysema in mice using automated micro-computed tomography. PLoS One (2012) 1.14
Biological aspects of early osteoarthritis. Knee Surg Sports Traumatol Arthrosc (2011) 1.13
Alterations in adipose tissue during critical illness: An adaptive and protective response? Am J Respir Crit Care Med (2010) 1.13
Effects of MRI contrast agents on the stem cell phenotype. Cell Transplant (2010) 1.13
Interventions for preventing critical illness polyneuropathy and critical illness myopathy. Cochrane Database Syst Rev (2014) 1.12