Published in J Neurochem on May 15, 2009
Glial cells in (patho)physiology. J Neurochem (2012) 1.89
Rivastigmine lowers Aβ and increases sAPPα levels, which parallel elevated synaptic markers and metabolic activity in degenerating primary rat neurons. PLoS One (2011) 1.06
Signal pathways in astrocytes activated by cross-talk between of astrocytes and mast cells through CD40-CD40L. J Neuroinflammation (2011) 0.96
Astrocytes as secretory cells of the central nervous system: idiosyncrasies of vesicular secretion. EMBO J (2016) 0.95
What do we know about gliotransmitter release from astrocytes? Philos Trans R Soc Lond B Biol Sci (2014) 0.89
REST/NRSF governs the expression of dense-core vesicle gliosecretion in astrocytes. J Cell Biol (2011) 0.88
Regulated exocytosis in astrocytic signal integration. Neurochem Int (2010) 0.87
Cyclic AMP signaling restricts activation and promotes maturation and antioxidant defenses in astrocytes. BMC Genomics (2016) 0.80
Evidence for the existence of secretory granule (dense-core vesicle)-based inositol 1,4,5-trisphosphate-dependent Ca2+ signaling system in astrocytes. PLoS One (2010) 0.79
Spinal astrocytes produce and secrete dynorphin neuropeptides. Neuropeptides (2013) 0.79
Astrocytic Pathological Calcium Homeostasis and Impaired Vesicle Trafficking in Neurodegeneration. Int J Mol Sci (2017) 0.78
Syntaxin 4 is concentrated on plasma membrane of astrocytes. Neuroscience (2014) 0.77
Loose excitation-secretion coupling in astrocytes. Glia (2015) 0.76
Modeling of glucose-induced cAMP oscillations in pancreatic β cells: cAMP rocks when metabolism rolls. Biophys J (2015) 0.76
The ROP vesicle release factor is required in adult Drosophila glia for normal circadian behavior. Front Cell Neurosci (2015) 0.76
Glycosylated Chromogranin A: Potential Role in the Pathogenesis of Heart Failure. Curr Heart Fail Rep (2017) 0.75
Amyloid-β Impairs Vesicular Secretion in Neuronal and Astrocyte Peptidergic Transmission. Front Mol Neurosci (2017) 0.75
Activation of endosomal dynein motors by stepwise assembly of Rab7-RILP-p150Glued, ORP1L, and the receptor betalll spectrin. J Cell Biol (2007) 2.52
Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism. Nat Cell Biol (2011) 2.38
Effect of short-term carbohydrate overfeeding and long-term weight loss on liver fat in overweight humans. Am J Clin Nutr (2012) 1.80
The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking. J Cell Sci (2002) 1.74
The oxysterol-binding protein homologue ORP1L interacts with Rab7 and alters functional properties of late endocytic compartments. Mol Biol Cell (2005) 1.46
The OSBP-related proteins: a novel protein family involved in vesicle transport, cellular lipid metabolism, and cell signalling. Biochim Biophys Acta (2003) 1.46
The extended granin family: structure, function, and biomedical implications. Endocr Rev (2011) 1.43
Imprinted Nesp55 influences behavioral reactivity to novel environments. Mol Cell Biol (2005) 1.25
OSBP-related protein 8 (ORP8) suppresses ABCA1 expression and cholesterol efflux from macrophages. J Biol Chem (2007) 1.23
The mammalian oxysterol-binding protein-related proteins (ORPs) bind 25-hydroxycholesterol in an evolutionarily conserved pocket. Biochem J (2007) 1.20
ALS-linked P56S-VAPB, an aggregated loss-of-function mutant of VAPB, predisposes motor neurons to ER stress-related death by inducing aggregation of co-expressed wild-type VAPB. J Neurochem (2009) 1.18
Endogenous plasma membrane t-SNARE syntaxin 4 is present in rab11 positive endosomal membranes and associates with cortical actin cytoskeleton. FEBS Lett (2002) 1.16
OSBP-related protein 2 is a sterol receptor on lipid droplets that regulates the metabolism of neutral lipids. J Lipid Res (2009) 1.09
Neuronal ceroid lipofuscinosis protein CLN3 interacts with motor proteins and modifies location of late endosomal compartments. Cell Mol Life Sci (2012) 1.09
Fibroblast growth factor-21 (FGF21) regulates low-density lipoprotein receptor (LDLR) levels in cells via the E3-ubiquitin ligase Mylip/Idol and the Canopy2 (Cnpy2)/Mylip-interacting saposin-like protein (Msap). J Biol Chem (2012) 1.07
The two variants of oxysterol binding protein-related protein-1 display different tissue expression patterns, have different intracellular localization, and are functionally distinct. Mol Biol Cell (2003) 1.07
Analysis of the Munc18b-syntaxin binding interface. Use of a mutant Munc18b to dissect the functions of syntaxins 2 and 3. J Biol Chem (2002) 1.07
PNPLA3 mediates hepatocyte triacylglycerol remodeling. J Lipid Res (2014) 1.05
Hypoxia up-regulates the angiogenic cytokine secretoneurin via an HIF-1alpha- and basic FGF-dependent pathway in muscle cells. FASEB J (2007) 1.05
Characteristics of oxysterol binding proteins. Int Rev Cytol (2008) 1.03
Role of ORPs in sterol transport from plasma membrane to ER and lipid droplets in mammalian cells. Traffic (2010) 1.03
PNPLA3 is regulated by glucose in human hepatocytes, and its I148M mutant slows down triglyceride hydrolysis. Am J Physiol Endocrinol Metab (2012) 1.03
The angiogenic factor secretoneurin induces coronary angiogenesis in a model of myocardial infarction by stimulation of vascular endothelial growth factor signaling in endothelial cells. Circulation (2012) 1.02
OSBPL10, a novel candidate gene for high triglyceride trait in dyslipidemic Finnish subjects, regulates cellular lipid metabolism. J Mol Med (Berl) (2009) 1.02
ORP2, a homolog of oxysterol binding protein, regulates cellular cholesterol metabolism. J Lipid Res (2002) 1.01
Podocalyxin is a novel polysialylated neural adhesion protein with multiple roles in neural development and synapse formation. PLoS One (2010) 1.01
Slp4-a/granuphilin-a interacts with syntaxin-2/3 in a Munc18-2-dependent manner. J Biol Chem (2005) 1.01
Expression patterns of MLC1 protein in the central and peripheral nervous systems. Neurobiol Dis (2007) 1.00
PLTP secreted by HepG2 cells resembles the high-activity PLTP form in human plasma. J Lipid Res (2003) 1.00
Sterol binding by OSBP-related protein 1L regulates late endosome motility and function. Cell Mol Life Sci (2010) 0.99
Oxysterol binding protein induces upregulation of SREBP-1c and enhances hepatic lipogenesis. Arterioscler Thromb Vasc Biol (2007) 0.99
Synaptic proteins and SNARE complexes are localized in lipid rafts from rat brain synaptosomes. Biochem Biophys Res Commun (2005) 0.99
Effect of epsilon toxin-GFP on MDCK cells and renal tubules in vivo. J Histochem Cytochem (2004) 0.98
The neuropeptide secretoneurin acts as a direct angiogenic cytokine in vitro and in vivo. Circulation (2004) 0.98
Secretoneurin, an angiogenic neuropeptide, induces postnatal vasculogenesis. Circulation (2004) 0.97
Overexpression of OSBP-related protein 2 (ORP2) induces changes in cellular cholesterol metabolism and enhances endocytosis. Biochem J (2005) 0.97
Evidence for the involvement of cAMP-GEF (Epac) pathway in amylase release from the rat parotid gland. Arch Biochem Biophys (2004) 0.97
Binding of epsilon-toxin from Clostridium perfringens in the nervous system. Vet Microbiol (2008) 0.97
Isolation and partial characterization of the inactive and active forms of human plasma phospholipid transfer protein (PLTP). J Biol Chem (2002) 0.97
Adipose tissue gene expression analysis reveals changes in inflammatory, mitochondrial respiratory and lipid metabolic pathways in obese insulin-resistant subjects. BMC Med Genomics (2012) 0.96
Expression of human OSBP-related protein 1L in macrophages enhances atherosclerotic lesion development in LDL receptor-deficient mice. Arterioscler Thromb Vasc Biol (2007) 0.95
Hepatic gene expression and lipid parameters in complement C3(-/-) mice that do not develop ethanol-induced steatosis. J Hepatol (2007) 0.95
Distribution of synaptobrevin/VAMP 1 and 2 in rat brain. J Chem Neuroanat (2005) 0.95
Gene therapy with the angiogenic cytokine secretoneurin induces therapeutic angiogenesis by a nitric oxide-dependent mechanism. Circ Res (2009) 0.95
Targeting of OSBP-related protein 3 (ORP3) to endoplasmic reticulum and plasma membrane is controlled by multiple determinants. Exp Cell Res (2005) 0.95
Molecular pathogenesis of megalencephalic leukoencephalopathy with subcortical cysts: mutations in MLC1 cause folding defects. Hum Mol Genet (2008) 0.95
Comparison of dorsocervical with abdominal subcutaneous adipose tissue in patients with and without antiretroviral therapy-associated lipodystrophy. Diabetes (2011) 0.94
A cytosolic splice variant of Cab45 interacts with Munc18b and impacts on amylase secretion by pancreatic acini. Mol Biol Cell (2007) 0.93
Splanchnic balance of free fatty acids, endocannabinoids, and lipids in subjects with nonalcoholic fatty liver disease. Gastroenterology (2010) 0.93
Cholesterol efflux from macrophage foam cells is enhanced by active phospholipid transfer protein through generation of two types of acceptor particles. Biochemistry (2007) 0.93
Genetic variation in PNPLA3 (adiponutrin) confers sensitivity to weight loss-induced decrease in liver fat in humans. Am J Clin Nutr (2011) 0.93
Age-dependent spontaneous hyperexcitability and impairment of GABAergic function in the hippocampus of mice lacking trkB. Cereb Cortex (2005) 0.92
Cajal-Retzius cells fail to trigger the developmental expression of the Cl- extruding co-transporter KCC2. Brain Res (2008) 0.92
Circulating triacylglycerol signatures in nonalcoholic fatty liver disease associated with the I148M variant in PNPLA3 and with obesity. Diabetes (2013) 0.92
Growth differentiation factor-9 induces Smad2 activation and inhibin B production in cultured human granulosa-luteal cells. J Clin Endocrinol Metab (2003) 0.92
Secretory sorting receptors carboxypeptidase E and secretogranin III in amyloid β-associated neural degeneration in Alzheimer's disease. Brain Pathol (2012) 0.91
Identification of urinary Gc-globulin as a novel biomarker for bladder cancer by two-dimensional fluorescent differential gel electrophoresis (2D-DIGE). J Proteomics (2012) 0.89
Relation of Rab26 to the amylase release from rat parotid acinar cells. Arch Oral Biol (2005) 0.88
Distribution of Clostridium perfringens epsilon toxin in the brains of acutely intoxicated mice and its effect upon glial cells. Toxicon (2007) 0.88
Synaptic proteins associate with a sub-set of lipid rafts when isolated from nerve endings at physiological temperature. Biochem Biophys Res Commun (2006) 0.88
Oxysterol-binding proteins: functions in cell regulation beyond lipid metabolism. Biochem Pharmacol (2013) 0.88
Munc18b is a major mediator of insulin exocytosis in rat pancreatic β-cells. Diabetes (2013) 0.88
The soleus muscle: MRI, anatomic and histologic findings in cadavers with clinical correlation of strain injury distribution. Skeletal Radiol (2012) 0.88
The R-Ras interaction partner ORP3 regulates cell adhesion. J Cell Sci (2008) 0.87
Active and low-active forms of serum phospholipid transfer protein in a normal Finnish population sample. J Lipid Res (2004) 0.87
Characterization of the high affinity binding of epsilon toxin from Clostridium perfringens to the renal system. Vet Microbiol (2012) 0.87
OSBP-related protein 8 (ORP8) regulates plasma and liver tissue lipid levels and interacts with the nucleoporin Nup62. PLoS One (2011) 0.86
Cytoplasmic oxysterol-binding proteins: sterol sensors or transporters? Chem Phys Lipids (2011) 0.86
Apolipoprotein E activates the low-activity form of human phospholipid transfer protein. Biochem Biophys Res Commun (2005) 0.85
Subfamily III of mammalian oxysterol-binding protein (OSBP) homologues: the expression and intracellular localization of ORP3, ORP6, and ORP7. Cell Tissue Res (2003) 0.85
Angiopoietin-like 4 mediates PPAR delta effect on lipoprotein lipase-dependent fatty acid uptake but not on beta-oxidation in myotubes. PLoS One (2012) 0.85
The effects of VEGF-A on atherosclerosis, lipoprotein profile, and lipoprotein lipase in hyperlipidaemic mouse models. Cardiovasc Res (2013) 0.85
Silencing of OSBP-related protein 8 (ORP8) modifies the macrophage transcriptome, nucleoporin p62 distribution, and migration capacity. Exp Cell Res (2012) 0.84
Assays for interaction between Rab7 and oxysterol binding protein related protein 1L (ORP1L). Methods Enzymol (2005) 0.83
Rab8 regulates ABCA1 cell surface expression and facilitates cholesterol efflux in primary human macrophages. Arterioscler Thromb Vasc Biol (2009) 0.83
OSBP-related protein 11 (ORP11) dimerizes with ORP9 and localizes at the Golgi-late endosome interface. Exp Cell Res (2010) 0.83
Altered hepatic lipid status and apolipoprotein A-I metabolism in mice lacking phospholipid transfer protein. Atherosclerosis (2006) 0.83
Ligand-dependent localization and function of ORP-VAP complexes at membrane contact sites. Cell Mol Life Sci (2014) 0.83
Is interfascial block with ultrasound-guided puncture useful in treatment of myofascial pain of the trapezius muscle? Clin J Pain (2011) 0.83
Content and traffic of taurine in hippocampal reactive astrocytes. Hippocampus (2011) 0.82
Cab45b, a Munc18b-interacting partner, regulates exocytosis in pancreatic beta-cells. J Biol Chem (2009) 0.82
Overexpression of OSBP-related protein 2 (ORP2) in CHO cells induces alterations of phospholipid species composition. Biochem Cell Biol (2005) 0.82
Secretogranin III is an astrocyte granin that is overexpressed in reactive glia. Cereb Cortex (2009) 0.81
Munc 18a binding to syntaxin 1A and 1B isoforms defines its localization at the plasma membrane and blocks SNARE assembly in a three-hybrid system assay. Mol Cell Neurosci (2002) 0.80
Schwann cells modulate short-term plasticity of cholinergic autaptic synapses. J Physiol (2008) 0.80
Quantitation of the active and low-active forms of human plasma phospholipid transfer protein by ELISA. J Lipid Res (2003) 0.80
Presence of cytoskeleton proteins in parotid glands and their roles during secretion. Arch Oral Biol (2004) 0.80
Protein kinase CK2-dependent phosphorylation of the human Regulators of Calcineurin reveals a novel mechanism regulating the calcineurin-NFATc signaling pathway. Biochim Biophys Acta (2013) 0.80
Sphingosine kinase-dependent directional migration of leukocytes in response to phorbol ester. Biochem Biophys Res Commun (2002) 0.80
Evidence for amylase release by cGMP via cAMP-dependent protein kinase in rat parotid acinar cells. Arch Oral Biol (2007) 0.80
Munc18b is an essential gene in mice whose expression is limiting for secretion by airway epithelial and mast cells. Biochem J (2012) 0.80
Modification of the lipidome in RAW264.7 macrophage subjected to stable silencing of oxysterol-binding proteins. Biochimie (2012) 0.79
VEGF and its role in the early development of the long bone epiphysis. J Anat (2010) 0.79
Protein kinase CK2 associates to lipid rafts and its pharmacological inhibition enhances neurotransmitter release. FEBS Lett (2010) 0.79
Secretoneurin in the peripheral ocular innervation. Invest Ophthalmol Vis Sci (2005) 0.79
Plasma phospholipid transfer protein fused with green fluorescent protein is secreted by HepG2 cells and displays phosphatidylcholine transfer activity. Biochem Cell Biol (2006) 0.79
Neuroendocrine secretory protein-55 (NESP-55) expression discriminates pancreatic endocrine tumors and pheochromocytomas from gastrointestinal and pulmonary carcinoids. Am J Surg Pathol (2004) 0.79
Single-agent chemotherapy with docetaxel significantly reduces PSA levels in patients with high-grade localized prostate cancers. Urol Int (2004) 0.79
Increased atherosclerotic lesions in LDL receptor deficient mice with hematopoietic nuclear receptor Rev-erbα knock- down. J Am Heart Assoc (2013) 0.79