Published in J Histochem Cytochem on July 01, 2004
Role of pore-forming toxins in bacterial infectious diseases. Microbiol Mol Biol Rev (2013) 1.91
Clostridium perfringens epsilon toxin: a malevolent molecule for animals and man? Toxins (Basel) (2013) 1.08
Gene-trap mutagenesis identifies mammalian genes contributing to intoxication by Clostridium perfringens ε-toxin. PLoS One (2011) 1.01
Evidence for a prepore stage in the action of Clostridium perfringens epsilon toxin. PLoS One (2011) 1.01
Dominant-negative inhibitors of the Clostridium perfringens epsilon-toxin. J Biol Chem (2009) 0.99
Functional analysis of neutralizing antibodies against Clostridium perfringens epsilon-toxin. Infect Immun (2007) 0.95
Clostridium perfringens epsilon toxin targets granule cells in the mouse cerebellum and stimulates glutamate release. PLoS One (2010) 0.93
Identification of amino acids important for binding of Clostridium perfringens epsilon toxin to host cells and to HAVCR1. Biochemistry (2012) 0.92
Observing the confinement potential of bacterial pore-forming toxin receptors inside rafts with nonblinking Eu(3+)-doped oxide nanoparticles. Biophys J (2012) 0.91
Identification of Small Molecule Inhibitors of Clostridium perfringens ε-Toxin Cytotoxicity Using a Cell-Based High-Throughput Screen. Toxins (Basel) (2010) 0.88
Oligomerization of Clostridium perfringens epsilon toxin is dependent upon caveolins 1 and 2. PLoS One (2012) 0.84
The Myelin and Lymphocyte Protein MAL Is Required for Binding and Activity of Clostridium perfringens ε-Toxin. PLoS Pathog (2015) 0.84
Obstructing toxin pathways by targeted pore blockage. Chem Rev (2012) 0.80
Receptor displacement in the cell membrane by hydrodynamic force amplification through nanoparticles. Biophys J (2013) 0.79
Correlation between in vitro cytotoxicity and in vivo lethal activity in mice of epsilon toxin mutants from Clostridium perfringens. PLoS One (2014) 0.77
Preparation of Specific Polyclonal Antibody Against the Recombinant Mutacin Produced by sfGFP Fusion Protein Technology. Open Microbiol J (2015) 0.76
Red Blood Cell Susceptibility to Pneumolysin: CORRELATION WITH MEMBRANE BIOCHEMICAL AND PHYSICAL PROPERTIES. J Biol Chem (2016) 0.75
Clostridium Perfringens Epsilon Toxin Binds to Membrane Lipids and Its Cytotoxic Action Depends on Sulfatide. PLoS One (2015) 0.75
Acute Effect of Pore-Forming Clostridium perfringens ε-Toxin on Compound Action Potentials of Optic Nerve of Mouse. eNeuro (2017) 0.75
Characterization of Annexin V Fusion with the Superfolder GFP in Liposomes Binding and Apoptosis Detection. Front Physiol (2017) 0.75
Remodeling of the gut microbiota and structural shifts in Preeclampsia patients in South China. Eur J Clin Microbiol Infect Dis (2016) 0.75
Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium. Genome Biol (2009) 3.66
Binary bacterial toxins: biochemistry, biology, and applications of common Clostridium and Bacillus proteins. Microbiol Mol Biol Rev (2004) 2.60
Clostridium perfringens epsilon-toxin shows structural similarity to the pore-forming toxin aerolysin. Nat Struct Mol Biol (2004) 1.55
Genotyping and phenotyping of beta2-toxigenic Clostridium perfringens fecal isolates associated with gastrointestinal diseases in piglets. J Clin Microbiol (2003) 1.32
Revised nomenclature of Clostridium difficile toxins and associated genes. J Med Microbiol (2005) 1.28
Dynamin inhibition blocks botulinum neurotoxin type A endocytosis in neurons and delays botulism. J Biol Chem (2011) 1.27
The IpaC carboxyterminal effector domain mediates Src-dependent actin polymerization during Shigella invasion of epithelial cells. PLoS Pathog (2009) 1.26
Rho family GTPases are required for activation of Jak/STAT signaling by G protein-coupled receptors. Mol Cell Biol (2003) 1.22
Association of Kv1.5 and Kv1.3 contributes to the major voltage-dependent K+ channel in macrophages. J Biol Chem (2006) 1.20
Rac GTPase instructs nuclear factor-kappaB activation by conveying the SCF complex and IkBalpha to the ruffling membranes. Mol Biol Cell (2003) 1.18
Organization and regulation of the neurotoxin genes in Clostridium botulinum and Clostridium tetani. Anaerobe (2004) 1.16
Amyloid β peptide oligomers directly activate NMDA receptors. Cell Calcium (2011) 1.15
Induction of transient macroapertures in endothelial cells through RhoA inhibition by Staphylococcus aureus factors. J Cell Biol (2006) 1.11
Receptor-mediated transcytosis of botulinum neurotoxin A through intestinal cell monolayers. Cell Microbiol (2007) 1.10
Rho GTPases link cytoskeletal rearrangements and activation processes induced via the tetraspanin CD82 in T lymphocytes. J Cell Sci (2002) 1.09
Cyclic AMP induces morphological changes of vascular smooth muscle cells by inhibiting a Rac-dependent signaling pathway. J Cell Physiol (2005) 1.09
Expression of botulinum neurotoxins A and E, and associated non-toxin genes, during the transition phase and stability at high temperature: analysis by quantitative reverse transcription-PCR. Microbiology (2006) 1.09
Clostridium perfringens epsilon toxin: a malevolent molecule for animals and man? Toxins (Basel) (2013) 1.08
Interaction between the two subdomains of the C-terminal part of the botulinum neurotoxin A is essential for the generation of protective antibodies. FEBS Lett (2004) 1.07
Interaction of Clostridium perfringens iota-toxin with lipid bilayer membranes. Demonstration of channel formation by the activated binding component Ib and channel block by the enzyme component Ia. J Biol Chem (2001) 1.07
Ectonucleotidases in the digestive system: focus on NTPDase3 localization. Am J Physiol Gastrointest Liver Physiol (2011) 1.07
Expression of cnf1 by Escherichia coli J96 involves a large upstream DNA region including the hlyCABD operon, and is regulated by the RfaH protein. Mol Microbiol (2003) 1.06
BotR/A and TetR are alternative RNA polymerase sigma factors controlling the expression of the neurotoxin and associated protein genes in Clostridium botulinum type A and Clostridium tetani. Mol Microbiol (2005) 1.06
Clostridium sordellii lethal toxin kills mice by inducing a major increase in lung vascular permeability. Am J Pathol (2007) 1.06
Detection by PCR-enzyme-linked immunosorbent assay of Clostridium botulinum in fish and environmental samples from a coastal area in northern France. Appl Environ Microbiol (2002) 1.05
Extracellular ATP and P2 receptors are required for IL-8 to induce neutrophil migration. Cytokine (2009) 1.03
Bacterial protein toxins and lipids: pore formation or toxin entry into cells. Biol Cell (2006) 1.03
Regulation of toxin and bacteriocin gene expression in Clostridium by interchangeable RNA polymerase sigma factors. Mol Microbiol (2006) 1.02
A phosphatidylserine-binding site in the cytosolic fragment of Clostridium sordellii lethal toxin facilitates glucosylation of membrane-bound Rac and is required for cytotoxicity. J Biol Chem (2004) 1.02
Clostridium difficile toxin B causes apoptosis in epithelial cells by thrilling mitochondria. Involvement of ATP-sensitive mitochondrial potassium channels. J Biol Chem (2007) 1.02
Clostridium perfringens epsilon toxin rapidly decreases membrane barrier permeability of polarized MDCK cells. Cell Microbiol (2003) 1.01
Clostridium perfringens delta toxin is sequence related to beta toxin, NetB, and Staphylococcus pore-forming toxins, but shows functional differences. PLoS One (2008) 1.01
Podocalyxin is a novel polysialylated neural adhesion protein with multiple roles in neural development and synapse formation. PLoS One (2010) 1.01
Quantitative profiling of the detergent-resistant membrane proteome of iota-b toxin induced vero cells. J Proteome Res (2005) 1.00
Synaptic proteins and SNARE complexes are localized in lipid rafts from rat brain synaptosomes. Biochem Biophys Res Commun (2005) 0.99
Clostridium perfringens iota toxin: characterization of the cell-associated iota b complex. Biochem J (2002) 0.98
Binding of epsilon-toxin from Clostridium perfringens in the nervous system. Vet Microbiol (2008) 0.97
Characterization of botulinum neurotoxin type A neutralizing monoclonal antibodies and influence of their half-lives on therapeutic activity. PLoS One (2010) 0.97
Genetic relatedness of Clostridium difficile isolates from various origins determined by triple-locus sequence analysis based on toxin regulatory genes tcdC, tcdR, and cdtR. J Clin Microbiol (2008) 0.96
Distribution of synaptobrevin/VAMP 1 and 2 in rat brain. J Chem Neuroanat (2005) 0.95
Differential Involvement of ERK2 and p38 in platelet adhesion to collagen. J Biol Chem (2005) 0.95
Rac GTPase plays an essential role in exocytosis by controlling the fusion competence of release sites. J Neurosci (2002) 0.94
Targeting membrane trafficking in infection prophylaxis: dynamin inhibitors. Trends Cell Biol (2012) 0.94
Differential requirement for the translocation of clostridial binary toxins: iota toxin requires a membrane potential gradient. FEBS Lett (2007) 0.94
Regulated expression of the beta2-toxin gene (cpb2) in Clostridium perfringens type a isolates from horses with gastrointestinal diseases. J Clin Microbiol (2005) 0.94
Detergent-resistant membrane microdomains facilitate Ib oligomer formation and biological activity of Clostridium perfringens iota-toxin. Infect Immun (2004) 0.93
Clostridium perfringens epsilon toxin targets granule cells in the mouse cerebellum and stimulates glutamate release. PLoS One (2010) 0.93
Endocytosis and toxicity of clostridial binary toxins depend on a clathrin-independent pathway regulated by Rho-GDI. Cell Microbiol (2010) 0.92
Endogenous hemichannels play a role in the release of ATP from Xenopus oocytes. J Cell Physiol (2006) 0.92
Differential entry of botulinum neurotoxin A into neuronal and intestinal cells. Cell Microbiol (2008) 0.92
Purification and characterization of a UDP-glucosyltransferase produced by Legionella pneumophila. Infect Immun (2003) 0.91
Identification of the channel-forming domain of Clostridium perfringens Epsilon-toxin (ETX). Biochim Biophys Acta (2009) 0.91
Observing the confinement potential of bacterial pore-forming toxin receptors inside rafts with nonblinking Eu(3+)-doped oxide nanoparticles. Biophys J (2012) 0.91
Clostridium perfringens iota toxin. Mapping of the Ia domain involved in docking with Ib and cellular internalization. J Biol Chem (2002) 0.90
Two-component systems are involved in the regulation of botulinum neurotoxin synthesis in Clostridium botulinum type A strain Hall. PLoS One (2012) 0.90
Rac1 inactivation by lethal toxin from Clostridium sordellii modifies focal adhesions upstream of actin depolymerization. Cell Microbiol (2009) 0.89
Modification of epithelial cell barrier permeability and intercellular junctions by Clostridium sordellii lethal toxins. Cell Microbiol (2006) 0.89
NTPDase1 controls IL-8 production by human neutrophils. J Immunol (2011) 0.89
Tailored ß-cyclodextrin blocks the translocation pores of binary exotoxins from C. botulinum and C. perfringens and protects cells from intoxication. PLoS One (2011) 0.89
Clostridium septicum alpha-toxin forms pores and induces rapid cell necrosis. Toxicon (2009) 0.89
Regulation of exocytotic protein expression and Ca2+-dependent peptide secretion in astrocytes. J Neurochem (2009) 0.88
Distribution of Clostridium perfringens epsilon toxin in the brains of acutely intoxicated mice and its effect upon glial cells. Toxicon (2007) 0.88
Membrane Interaction of botulinum neurotoxin A translocation (T) domain. The belt region is a regulatory loop for membrane interaction. J Biol Chem (2008) 0.88
Synaptic proteins associate with a sub-set of lipid rafts when isolated from nerve endings at physiological temperature. Biochem Biophys Res Commun (2006) 0.88
The soleus muscle: MRI, anatomic and histologic findings in cadavers with clinical correlation of strain injury distribution. Skeletal Radiol (2012) 0.88
Aeromonas exoenzyme T of Aeromonas salmonicida is a bifunctional protein that targets the host cytoskeleton. J Biol Chem (2007) 0.87
Characterization of the high affinity binding of epsilon toxin from Clostridium perfringens to the renal system. Vet Microbiol (2012) 0.87
Transcytosis of iota-toxin across polarized CaCo-2 cells. Mol Microbiol (2002) 0.87
The long-lived nature of clostridium perfringens iota toxin in mammalian cells induces delayed apoptosis. Infect Immun (2009) 0.86
RhoA GTPase and F-actin dynamically regulate the permeability of Cx43-made channels in rat cardiac myocytes. J Biol Chem (2008) 0.86
Preferential entry of botulinum neurotoxin A Hc domain through intestinal crypt cells and targeting to cholinergic neurons of the mouse intestine. PLoS Pathog (2012) 0.86
Clostridial binary toxins: iota and C2 family portraits. Front Cell Infect Microbiol (2011) 0.86
Haemorrhagic toxin and lethal toxin from Clostridium sordellii strain vpi9048: molecular characterization and comparative analysis of substrate specificity of the large clostridial glucosylating toxins. Cell Microbiol (2014) 0.85
CD44 Promotes intoxication by the clostridial iota-family toxins. PLoS One (2012) 0.85
Production and characterisation of a neutralising chimeric antibody against botulinum neurotoxin A. PLoS One (2010) 0.85
Attack of the nervous system by Clostridium perfringens Epsilon toxin: from disease to mode of action on neural cells. Toxicon (2013) 0.84
Effect of galantamine on the human alpha7 neuronal nicotinic acetylcholine receptor, the Torpedo nicotinic acetylcholine receptor and spontaneous cholinergic synaptic activity. Br J Pharmacol (2005) 0.83
Is interfascial block with ultrasound-guided puncture useful in treatment of myofascial pain of the trapezius muscle? Clin J Pain (2011) 0.83
Antibiotic-induced expression of a cryptic cpb2 gene in equine beta2-toxigenic Clostridium perfringens. Mol Microbiol (2005) 0.82
Interactions of high-affinity cationic blockers with the translocation pores of B. anthracis, C. botulinum, and C. perfringens binary toxins. Biophys J (2012) 0.82
Evidence that membrane rafts are not required for the action of Clostridium perfringens enterotoxin. Infect Immun (2008) 0.81