| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men.
|
J Clin Endocrinol Metab
|
2002
|
6.79
|
|
2
|
Fatty liver: a novel component of the metabolic syndrome.
|
Arterioscler Thromb Vasc Biol
|
2007
|
3.83
|
|
3
|
Prediction of non-alcoholic fatty liver disease and liver fat using metabolic and genetic factors.
|
Gastroenterology
|
2009
|
3.67
|
|
4
|
Comparison of basal insulin added to oral agents versus twice-daily premixed insulin as initial insulin therapy for type 2 diabetes.
|
Diabetes Care
|
2005
|
3.60
|
|
5
|
One-year treatment with exenatide improves beta-cell function, compared with insulin glargine, in metformin-treated type 2 diabetic patients: a randomized, controlled trial.
|
Diabetes Care
|
2009
|
2.75
|
|
6
|
Acquired obesity is associated with changes in the serum lipidomic profile independent of genetic effects--a monozygotic twin study.
|
PLoS One
|
2007
|
2.38
|
|
7
|
FGF-21 as a biomarker for muscle-manifesting mitochondrial respiratory chain deficiencies: a diagnostic study.
|
Lancet Neurol
|
2011
|
2.36
|
|
8
|
Gene expression in human NAFLD.
|
Am J Physiol Gastrointest Liver Physiol
|
2008
|
2.33
|
|
9
|
From the metabolic syndrome to NAFLD or vice versa?
|
Dig Liver Dis
|
2010
|
2.24
|
|
10
|
Liver fat in the metabolic syndrome.
|
J Clin Endocrinol Metab
|
2007
|
2.17
|
|
11
|
Adipose tissue inflammation and increased ceramide content characterize subjects with high liver fat content independent of obesity.
|
Diabetes
|
2007
|
2.08
|
|
12
|
Genes involved in fatty acid partitioning and binding, lipolysis, monocyte/macrophage recruitment, and inflammation are overexpressed in the human fatty liver of insulin-resistant subjects.
|
Diabetes
|
2007
|
2.06
|
|
13
|
Global transcript profiles of fat in monozygotic twins discordant for BMI: pathways behind acquired obesity.
|
PLoS Med
|
2008
|
1.94
|
|
14
|
Effects of rosiglitazone and metformin on liver fat content, hepatic insulin resistance, insulin clearance, and gene expression in adipose tissue in patients with type 2 diabetes.
|
Diabetes
|
2004
|
1.92
|
|
15
|
Association of lipidome remodeling in the adipocyte membrane with acquired obesity in humans.
|
PLoS Biol
|
2011
|
1.89
|
|
16
|
Effect of short-term carbohydrate overfeeding and long-term weight loss on liver fat in overweight humans.
|
Am J Clin Nutr
|
2012
|
1.80
|
|
17
|
Increased liver fat, impaired insulin clearance, and hepatic and adipose tissue insulin resistance in type 2 diabetes.
|
Gastroenterology
|
2008
|
1.78
|
|
18
|
Effects of identical weight loss on body composition and features of insulin resistance in obese women with high and low liver fat content.
|
Diabetes
|
2003
|
1.71
|
|
19
|
Genetic variation in PNPLA3 but not APOC3 influences liver fat in non-alcoholic fatty liver disease.
|
J Gastroenterol Hepatol
|
2012
|
1.67
|
|
20
|
Physical inactivity and obesity: a vicious circle.
|
Obesity (Silver Spring)
|
2008
|
1.65
|
|
21
|
Effect of liver fat on insulin clearance.
|
Am J Physiol Endocrinol Metab
|
2007
|
1.64
|
|
22
|
Dietary fat content modifies liver fat in overweight nondiabetic subjects.
|
J Clin Endocrinol Metab
|
2005
|
1.62
|
|
23
|
Lowering of LDL cholesterol rather than moderate weight loss improves endothelium-dependent vasodilatation in obese women with previous gestational diabetes.
|
Diabetes Care
|
2003
|
1.56
|
|
24
|
Effects of exenatide on measures of β-cell function after 3 years in metformin-treated patients with type 2 diabetes.
|
Diabetes Care
|
2011
|
1.53
|
|
25
|
Comparison of lipid and fatty acid composition of the liver, subcutaneous and intra-abdominal adipose tissue, and serum.
|
Obesity (Silver Spring)
|
2009
|
1.39
|
|
26
|
Increased fat accumulation in the liver in HIV-infected patients with antiretroviral therapy-associated lipodystrophy.
|
AIDS
|
2002
|
1.34
|
|
27
|
Impaired responsiveness to NO in newly diagnosed patients with rheumatoid arthritis.
|
Arterioscler Thromb Vasc Biol
|
2002
|
1.33
|
|
28
|
The contribution of visceral adipose tissue to splanchnic cortisol production in healthy humans.
|
Diabetes
|
2005
|
1.32
|
|
29
|
Liver-fat accumulation and insulin resistance in obese women with previous gestational diabetes.
|
Obes Res
|
2002
|
1.31
|
|
30
|
Fatty acid metabolism in adipose tissue, muscle and liver in health and disease.
|
Essays Biochem
|
2006
|
1.27
|
|
31
|
Long-term effects of fenofibrate on carotid intima-media thickness and augmentation index in subjects with type 2 diabetes mellitus.
|
J Am Coll Cardiol
|
2008
|
1.26
|
|
32
|
Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes.
|
PLoS Genet
|
2010
|
1.24
|
|
33
|
Hepatic stearoyl-CoA desaturase (SCD)-1 activity and diacylglycerol but not ceramide concentrations are increased in the nonalcoholic human fatty liver.
|
Diabetes
|
2008
|
1.24
|
|
34
|
Congruence between NOTCH3 mutations and GOM in 131 CADASIL patients.
|
Brain
|
2009
|
1.23
|
|
35
|
Brain metabolic alterations in patients with type 1 diabetes-hyperglycemia-induced injury.
|
J Cereb Blood Flow Metab
|
2004
|
1.23
|
|
36
|
Overexpression of 11beta-hydroxysteroid dehydrogenase-1 in adipose tissue is associated with acquired obesity and features of insulin resistance: studies in young adult monozygotic twins.
|
J Clin Endocrinol Metab
|
2004
|
1.21
|
|
37
|
Exenatide affects circulating cardiovascular risk biomarkers independently of changes in body composition.
|
Diabetes Care
|
2010
|
1.21
|
|
38
|
Liver fat is increased in type 2 diabetic patients and underestimated by serum alanine aminotransferase compared with equally obese nondiabetic subjects.
|
Diabetes Care
|
2007
|
1.16
|
|
39
|
Growth patterns in young adult monozygotic twin pairs discordant and concordant for obesity.
|
Twin Res
|
2004
|
1.15
|
|
40
|
Body fat distribution and cortisol metabolism in healthy men: enhanced 5beta-reductase and lower cortisol/cortisone metabolite ratios in men with fatty liver.
|
J Clin Endocrinol Metab
|
2003
|
1.13
|
|
41
|
Altered miRNA processing disrupts brown/white adipocyte determination and associates with lipodystrophy.
|
J Clin Invest
|
2014
|
1.12
|
|
42
|
Effects of chronic rosiglitazone therapy on gene expression in human adipose tissue in vivo in patients with type 2 diabetes.
|
J Clin Endocrinol Metab
|
2006
|
1.11
|
|
43
|
Effects of insulin therapy on liver fat content and hepatic insulin sensitivity in patients with type 2 diabetes.
|
Am J Physiol Endocrinol Metab
|
2006
|
1.10
|
|
44
|
Uridine supplementation for the treatment of antiretroviral therapy-associated lipoatrophy: a randomized, double-blind, placebo-controlled trial.
|
Antivir Ther
|
2007
|
1.09
|
|
45
|
Rosiglitazone in the treatment of HAART-associated lipodystrophy--a randomized double-blind placebo-controlled study.
|
Antivir Ther
|
2003
|
1.09
|
|
46
|
Cholesterol synthesis is increased and absorption decreased in non-alcoholic fatty liver disease independent of obesity.
|
J Hepatol
|
2010
|
1.08
|
|
47
|
One-year treatment with exenatide vs. insulin glargine: effects on postprandial glycemia, lipid profiles, and oxidative stress.
|
Atherosclerosis
|
2010
|
1.07
|
|
48
|
Acquired obesity is associated with increased liver fat, intra-abdominal fat, and insulin resistance in young adult monozygotic twins.
|
Am J Physiol Endocrinol Metab
|
2004
|
1.06
|
|
49
|
Adipose tissue inflammation and liver fat in patients with highly active antiretroviral therapy-associated lipodystrophy.
|
Am J Physiol Endocrinol Metab
|
2008
|
1.06
|
|
50
|
Genetic variation in the ADIPOR2 gene is associated with liver fat content and its surrogate markers in three independent cohorts.
|
Eur J Endocrinol
|
2009
|
1.06
|
|
51
|
Non-alcoholic and alcoholic fatty liver disease - two diseases of affluence associated with the metabolic syndrome and type 2 diabetes: the FIN-D2D survey.
|
BMC Public Health
|
2010
|
1.05
|
|
52
|
PNPLA3 mediates hepatocyte triacylglycerol remodeling.
|
J Lipid Res
|
2014
|
1.05
|
|
53
|
Acquired obesity and poor physical fitness impair expression of genes of mitochondrial oxidative phosphorylation in monozygotic twins discordant for obesity.
|
Am J Physiol Endocrinol Metab
|
2008
|
1.04
|
|
54
|
Acquired obesity increases CD68 and tumor necrosis factor-alpha and decreases adiponectin gene expression in adipose tissue: a study in monozygotic twins.
|
J Clin Endocrinol Metab
|
2006
|
1.04
|
|
55
|
Effects of equal weight loss with orlistat and placebo on body fat and serum fatty acid composition and insulin resistance in obese women.
|
Am J Clin Nutr
|
2004
|
1.03
|
|
56
|
PNPLA3 is regulated by glucose in human hepatocytes, and its I148M mutant slows down triglyceride hydrolysis.
|
Am J Physiol Endocrinol Metab
|
2012
|
1.03
|
|
57
|
Postprandial lipemia associates with liver fat content.
|
J Clin Endocrinol Metab
|
2007
|
1.02
|
|
58
|
Liver fat and lipid oxidation in humans.
|
Liver Int
|
2009
|
1.01
|
|
59
|
Insulin-like growth factor binding protein 1 as a novel specific marker of hepatic insulin sensitivity.
|
J Clin Endocrinol Metab
|
2008
|
1.01
|
|
60
|
Comparison of the relative contributions of intra-abdominal and liver fat to components of the metabolic syndrome.
|
Obesity (Silver Spring)
|
2010
|
0.99
|
|
61
|
Inhibition of platelet-collagen interaction: an in vivo action of insulin abolished by insulin resistance in obesity.
|
Arterioscler Thromb Vasc Biol
|
2002
|
0.99
|
|
62
|
Arterial stiffness in HIV-infected patients receiving highly active antiretroviral therapy.
|
Antivir Ther
|
2005
|
0.99
|
|
63
|
Circulating concentration of adiponectin and its expression in subcutaneous adipose tissue in patients with highly active antiretroviral therapy-associated lipodystrophy.
|
J Clin Endocrinol Metab
|
2003
|
0.98
|
|
64
|
Insulin- and exercise-stimulated skeletal muscle blood flow and glucose uptake in obese men.
|
Obes Res
|
2003
|
0.97
|
|
65
|
Adipose tissue gene expression analysis reveals changes in inflammatory, mitochondrial respiratory and lipid metabolic pathways in obese insulin-resistant subjects.
|
BMC Med Genomics
|
2012
|
0.96
|
|
66
|
Insulin regulation of MCP-1 in human adipose tissue of obese and lean women.
|
Am J Physiol Endocrinol Metab
|
2008
|
0.95
|
|
67
|
Prediction of non-alcoholic fatty-liver disease and liver fat content by serum molecular lipids.
|
Diabetologia
|
2013
|
0.95
|
|
68
|
Rosiglitazone reduces liver fat and insulin requirements and improves hepatic insulin sensitivity and glycemic control in patients with type 2 diabetes requiring high insulin doses.
|
J Clin Endocrinol Metab
|
2007
|
0.94
|
|
69
|
Comparison of dorsocervical with abdominal subcutaneous adipose tissue in patients with and without antiretroviral therapy-associated lipodystrophy.
|
Diabetes
|
2011
|
0.94
|
|
70
|
Splanchnic balance of free fatty acids, endocannabinoids, and lipids in subjects with nonalcoholic fatty liver disease.
|
Gastroenterology
|
2010
|
0.93
|
|
71
|
Genetic variation in PNPLA3 (adiponutrin) confers sensitivity to weight loss-induced decrease in liver fat in humans.
|
Am J Clin Nutr
|
2011
|
0.93
|
|
72
|
3.5 years of insulin therapy with insulin glargine improves in vivo endothelial function in type 2 diabetes.
|
Arterioscler Thromb Vasc Biol
|
2003
|
0.93
|
|
73
|
Circulating triacylglycerol signatures in nonalcoholic fatty liver disease associated with the I148M variant in PNPLA3 and with obesity.
|
Diabetes
|
2013
|
0.92
|
|
74
|
Genetic factors contribute to variation in serum alanine aminotransferase activity independent of obesity and alcohol: a study in monozygotic and dizygotic twins.
|
J Hepatol
|
2009
|
0.92
|
|
75
|
Increased resting energy expenditure, fat oxidation, and food intake in patients with highly active antiretroviral therapy-associated lipodystrophy.
|
Am J Physiol Endocrinol Metab
|
2006
|
0.91
|
|
76
|
Endothelial dysfunction in human diabetes.
|
Curr Diab Rep
|
2002
|
0.91
|
|
77
|
Expression of adipogenic transcription factors, peroxisome proliferator-activated receptor gamma co-activator 1, IL-6 and CD45 in subcutaneous adipose tissue in lipodystrophy associated with highly active antiretroviral therapy.
|
AIDS
|
2003
|
0.89
|
|
78
|
Obesity-related derangements of coagulation and fibrinolysis: a study of obesity-discordant monozygotic twin pairs.
|
Obesity (Silver Spring)
|
2011
|
0.88
|
|
79
|
Effects of acquired obesity on endothelial function in monozygotic twins.
|
Obesity (Silver Spring)
|
2006
|
0.88
|
|
80
|
Insulin-induced decreases in aortic wave reflection and central systolic pressure are impaired in type 2 diabetes.
|
Diabetes Care
|
2002
|
0.87
|
|
81
|
Effects of rosiglitazone on gene expression in subcutaneous adipose tissue in highly active antiretroviral therapy-associated lipodystrophy.
|
Am J Physiol Endocrinol Metab
|
2004
|
0.87
|
|
82
|
Isoform-specific alanine aminotransferase measurement can distinguish hepatic from extrahepatic injury in humans.
|
Int J Mol Med
|
2012
|
0.86
|
|
83
|
Concentrations of insulin glargine and its metabolites during long-term insulin therapy in type 2 diabetic patients and comparison of effects of insulin glargine, its metabolites, IGF-I, and human insulin on insulin and igf-I receptor signaling.
|
Diabetes
|
2013
|
0.86
|
|
84
|
Increased coagulation factor VIII, IX, XI and XII activities in non-alcoholic fatty liver disease.
|
Liver Int
|
2010
|
0.85
|
|
85
|
Diabetes: Should we treat infection or inflammation to prevent T2DM?
|
Nat Rev Endocrinol
|
2012
|
0.82
|
|
86
|
Arterial stiffness and insulin resistance.
|
Semin Vasc Med
|
2002
|
0.82
|
|
87
|
Liver fat content and hepatic insulin sensitivity in overweight patients with type 1 diabetes.
|
J Clin Endocrinol Metab
|
2014
|
0.81
|
|
88
|
Metabolomic analysis of polar metabolites in lipoprotein fractions identifies lipoprotein-specific metabolic profiles and their association with insulin resistance.
|
Mol Biosyst
|
2012
|
0.81
|
|
89
|
Waist circumference adjusted for body mass index and intra-abdominal fat mass.
|
PLoS One
|
2012
|
0.81
|
|
90
|
Allele-specific regulation of MTTP expression influences the risk of ischemic heart disease.
|
J Lipid Res
|
2010
|
0.80
|
|
91
|
Exploring the lipoprotein composition using Bayesian regression on serum lipidomic profiles.
|
Bioinformatics
|
2007
|
0.80
|
|
92
|
Nonalcoholic fatty liver disease: detection of elevated nicotinamide adenine dinucleotide phosphate with in vivo 3.0-T 31P MR spectroscopy with proton decoupling.
|
Radiology
|
2010
|
0.80
|
|
93
|
Expression of ceramide-metabolising enzymes in subcutaneous and intra-abdominal human adipose tissue.
|
Lipids Health Dis
|
2012
|
0.80
|
|
94
|
Effects of dietary interventions on liver volume in humans.
|
Obesity (Silver Spring)
|
2013
|
0.79
|
|
95
|
Glargine and regular human insulin similarly acutely enhance endothelium-dependent vasodilatation in normal subjects.
|
Arterioscler Thromb Vasc Biol
|
2003
|
0.79
|
|
96
|
OSBP-related proteins (ORPs) in human adipose depots and cultured adipocytes: evidence for impacts on the adipocyte phenotype.
|
PLoS One
|
2012
|
0.78
|
|
97
|
Adipocyte size is associated with NAFLD independent of obesity, fat distribution, and PNPLA3 genotype.
|
Obesity (Silver Spring)
|
2013
|
0.78
|
|
98
|
17β-Estradiol and estradiol fatty acyl esters and estrogen-converting enzyme expression in adipose tissue in obese men and women.
|
J Clin Endocrinol Metab
|
2013
|
0.77
|
|
99
|
Skeletal muscle mitochondrial DNA content and aerobic metabolism in patients with antiretroviral therapy-associated lipoatrophy.
|
J Antimicrob Chemother
|
2010
|
0.77
|
|
100
|
Out of the frying pan: dietary saturated fat influences nonalcoholic fatty liver disease.
|
J Clin Invest
|
2017
|
0.75
|
|
101
|
Insulin therapy and cardiovascular risk. Introduction.
|
Clin Cornerstone
|
2003
|
0.75
|
|
102
|
Differential effects of oral and transdermal estradiol treatment on circulating estradiol fatty acid ester concentrations in postmenopausal women.
|
J Clin Endocrinol Metab
|
2003
|
0.75
|
|
103
|
Michaela Diamant, 11 April 1962-9 April 2014.
|
Diabetologia
|
2014
|
0.75
|
|
104
|
The influence of sample collection methodology and sample preprocessing on the blood metabolic profile.
|
Bioanalysis
|
2015
|
0.75
|
|
105
|
Impact of non-alcoholic fatty liver disease on liver volume in humans.
|
Hepatol Res
|
2014
|
0.75
|
|
106
|
Obesity/insulin resistance rather than liver fat increases coagulation factor activities and expression in humans.
|
Thromb Haemost
|
2016
|
0.75
|
|
107
|
Diagnosis of nonalcoholic fatty liver disease (NAFLD).
|
Duodecim
|
1
|
0.75
|
|
108
|
Glycodelin responses to hyperinsulinaemic clamp vary according to basal serum glycodelin concentration.
|
Clin Endocrinol (Oxf)
|
2005
|
0.75
|