Published in BMC Cancer on July 20, 2009
Glucose transporter 1 (GLUT1) of anaerobic glycolysis as predictive and prognostic values in neoadjuvant chemoradiotherapy and laparoscopic surgery for locally advanced rectal cancer. Int J Colorectal Dis (2012) 1.53
Hesperetin impairs glucose uptake and inhibits proliferation of breast cancer cells. Cell Biochem Funct (2012) 1.44
Metabolic reprogramming: the emerging concept and associated therapeutic strategies. J Exp Clin Cancer Res (2015) 1.04
Prognostic significance of glucose transporter-1 (GLUT1) gene expression in rectal cancer after preoperative chemoradiotherapy. Surg Today (2011) 0.89
Down-regulation of MutS homolog 3 by hypoxia in human colorectal cancer. Biochim Biophys Acta (2012) 0.87
DPYD, TYMS, TYMP, TK1, and TK2 genetic expressions as response markers in locally advanced rectal cancer patients treated with fluoropyrimidine-based chemoradiotherapy. Biomed Res Int (2013) 0.83
Tumor dynamics in response to antiangiogenic therapy with oral metronomic topotecan and pazopanib in neuroblastoma xenografts. Transl Oncol (2013) 0.81
High glucose modulates antiproliferative effect and cytotoxicity of 5-fluorouracil in human colon cancer cells. DNA Cell Biol (2013) 0.81
N-myc downstream-regulated gene 2 expression is associated with glucose transport and correlated with prognosis in breast carcinoma. Breast Cancer Res (2014) 0.80
Vitamin C uncouples the Warburg metabolic switch in KRAS mutant colon cancer. Oncotarget (2016) 0.79
A combined gene signature of hypoxia and notch pathway in human glioblastoma and its prognostic relevance. PLoS One (2015) 0.79
ZnCl2 sustains the adriamycin-induced cell death inhibited by high glucose. Cell Death Dis (2016) 0.78
Oridonin induces autophagy via inhibition of glucose metabolism in p53-mutated colorectal cancer cells. Cell Death Dis (2017) 0.77
Significance of glycolytic metabolism-related protein expression in colorectal cancer, lymph node and hepatic metastasis. BMC Cancer (2016) 0.75
Morin Inhibits Proliferation of SW480 Colorectal Cancer Cells by Inducing Apoptosis Mediated by Reactive Oxygen Species Formation and Uncoupling of Warburg Effect. Front Pharmacol (2017) 0.75
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem (1987) 281.19
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha. Genes Dev (1998) 12.48
Cancer statistics, 2000. CA Cancer J Clin (2000) 12.32
Global cancer statistics in the year 2000. Lancet Oncol (2001) 11.11
Drug resistance and the solid tumor microenvironment. J Natl Cancer Inst (2007) 7.10
Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. Am J Pathol (1993) 6.55
Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma. Cancer Res (1996) 4.98
Oncogenic alterations of metabolism. Trends Biochem Sci (1999) 4.51
Cloning and characterization of a cDNA encoding the rat brain glucose-transporter protein. Proc Natl Acad Sci U S A (1986) 4.40
Hypoxia: importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy. Int J Radiat Biol (2006) 3.98
Intratumoral pO2 predicts survival in advanced cancer of the uterine cervix. Radiother Oncol (1993) 3.63
Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer. Cancer Res (2000) 3.35
Tumor mitochondria and the bioenergetics of cancer cells. Prog Exp Tumor Res (1978) 3.16
Mosaic blood vessels in tumors: frequency of cancer cells in contact with flowing blood. Proc Natl Acad Sci U S A (2000) 3.16
Detection and characterization of tumor hypoxia using pO2 histography. Antioxid Redox Signal (2007) 2.76
Cancer statistics for African Americans. CA Cancer J Clin (2002) 2.45
Fructose transporter in human spermatozoa and small intestine is GLUT5. J Biol Chem (1992) 2.35
Mammalian oxygen sensing, signalling and gene regulation. J Exp Biol (2000) 2.22
Predictors of stage of adoption for colorectal cancer screening. Prev Med (2000) 2.12
Characterization and expression of human HepG2/erythrocyte glucose-transporter gene. Diabetes (1988) 1.76
Prognostic impact of hypoxia-inducible factors 1alpha and 2alpha in colorectal cancer patients: correlation with tumor angiogenesis and cyclooxygenase-2 expression. Clin Cancer Res (2004) 1.62
Glycolysis, respiration, and anomalous gene expression in experimental hepatomas: G.H.A. Clowes memorial lecture. Cancer Res (1972) 1.54
[Origin of cancer cells]. Oncologia (1956) 1.52
Chemotherapy response evaluation with FDG-PET in patients with colorectal cancer. Ann Oncol (2007) 1.42
Hypoxic prostate/muscle pO2 ratio predicts for biochemical failure in patients with prostate cancer: preliminary findings. Urology (2002) 1.37
On the significance of glucolysis for cancer growth, with special reference to Morris rat hepatomas. J Natl Cancer Inst (1967) 1.36
Expression and prognostic significance of a panel of tissue hypoxia markers in head-and-neck squamous cell carcinomas. Int J Radiat Oncol Biol Phys (2007) 1.36
Functional expression of the human HepG2 and rat adipocyte glucose transporters in Xenopus oocytes. Comparison of kinetic parameters. J Biol Chem (1989) 1.33
Chronic inflammatory bowel disease and cancer. Hepatogastroenterology (2000) 1.32
The expression of p185(HER-2/neu) correlates with the stage of disease and survival in colorectal cancer. Gastroenterology (1997) 1.24
Comparison between pimonidazole binding, oxygen electrode measurements, and expression of endogenous hypoxia markers in cancer of the uterine cervix. Cytometry B Clin Cytom (2006) 1.20
Tumor marker utility and prognostic relevance of cathepsin B, cathepsin L, urokinase-type plasminogen activator, plasminogen activator inhibitor type-1, CEA and CA 19-9 in colorectal cancer. BMC Cancer (2008) 1.16
Hypoxia-inducible factor 1 (HIF-1) in cancer. Eur J Surg Oncol (2004) 1.14
Molecular detection of circulating cancer cells in the peripheral blood of patients with colorectal cancer by using membrane array with a multiple mRNA marker panel. Int J Oncol (2006) 1.04
Suppression of facilitative glucose transporter 1 mRNA can suppress tumor growth. Cancer Lett (2000) 1.00
Development and evaluation of a colorimetric membrane-array method for the detection of circulating tumor cells in the peripheral blood of Taiwanese patients with colorectal cancer. Int J Mol Med (2006) 0.98
Relationships among lactate concentration, blood flow and histopathologic profiles in rat C6 glioma. NMR Biomed (1996) 0.96
High correlations between primary tumours and loco-regional metastatic lymph nodes in non-small-cell lung cancer with respect to glucose transporter type 1-mediated 2-deoxy-2-F18-fluoro-D-glucose uptake. Eur J Cancer (2008) 0.96
Neoangiogenesis and expression of hypoxia-inducible factor 1alpha, vascular endothelial growth factor, and glucose transporter-1 in endometrioid type endometrium adenocarcinomas. Gynecol Oncol (2008) 0.92
Comparison of carcinoembryonic antigen prognostic value in serum and tumour tissue of patients with colorectal cancer. Colorectal Dis (2008) 0.92
Detection of circulating cancer cells with K-ras oncogene using membrane array. Cancer Lett (2005) 0.91
Preoperative staging of colorectal cancer: CT vs. integrated FDG PET/CT. Abdom Imaging (2008) 0.90
Endogenous hypoxia markers: case not proven! Adv Exp Med Biol (2008) 0.90
Expression analysis of facilitative glucose transporters (GLUTs) in human thyroid carcinoma cell lines and primary tumors. Mol Cell Endocrinol (2008) 0.89
Prognostic implications of glucose transporter protein-1 (glut-1) overexpression in bone and soft-tissue sarcomas. Jpn J Clin Oncol (2007) 0.86
Simultaneous detection of multiple mRNA markers CK19, CEA, c-Met, Her2/neu and hMAM with membrane array, an innovative technique with a great potential for breast cancer diagnosis. Cancer Lett (2005) 0.81
Expression of epidermal growth factor receptor messenger RNA in human colorectal carcinomas assessed by non-radioactive in-situ hybridization. Eur J Surg Oncol (1995) 0.81
[Expression of GLUT-1, p63 and DNA-Pkcs in serous ovarian tumors and their significance]. Zhonghua Zhong Liu Za Zhi (2007) 0.81
Modulating the radiation response. Stem Cells (1996) 0.80
Ets1 was significantly activated by ERK1/2 in mutant K-ras stably transfected human adrenocortical cells. DNA Cell Biol (2005) 0.79
Technical improvement of pO(2) measurements in breast cancer: investigation of the feasibility in patients and in vitro validation of the method. Strahlenther Onkol (2007) 0.76
Fatty acid metabolism pathway play an important role in carcinogenesis of human colorectal cancers by Microarray-Bioinformatics analysis. Cancer Lett (2006) 1.84
Cutting Edge: mechanical forces acting on T cells immobilized via the TCR complex can trigger TCR signaling. J Immunol (2010) 1.77
Activating KRAS mutations and overexpression of epidermal growth factor receptor as independent predictors in metastatic colorectal cancer patients treated with cetuximab. Ann Surg (2010) 1.36
Combination of tumor site-located CTL-associated antigen-4 blockade and systemic regulatory T-cell depletion induces tumor-destructive immune responses. Cancer Res (2007) 1.32
Detection of KRAS oncogene in peripheral blood as a predictor of the response to cetuximab plus chemotherapy in patients with metastatic colorectal cancer. Clin Cancer Res (2009) 1.23
A simple single-port laparoscopic-assisted technique for completely enclosing inguinal hernia in children. Am J Surg (2009) 1.22
Targeted Herceptin-dextran iron oxide nanoparticles for noninvasive imaging of HER2/neu receptors using MRI. J Biol Inorg Chem (2008) 1.20
One-trocar laparoscopic transperitoneal closure of inguinal hernia in children. World J Surg (2008) 1.17
Preoperative serum carcinoembryonic antigen, albumin and age are supplementary to UICC staging systems in predicting survival for colorectal cancer patients undergoing surgical treatment. BMC Cancer (2009) 1.14
Great potential of a panel of multiple hMTH1, SPD, ITGA11 and COL11A1 markers for diagnosis of patients with non-small cell lung cancer. Oncol Rep (2006) 1.12
Computational analysis of mRNA expression profiles identifies microRNA-29a/c as predictor of colorectal cancer early recurrence. PLoS One (2012) 1.12
Molecular detection of circulating tumor cells in the peripheral blood of patients with colorectal cancer using RT-PCR: significance of the prediction of postoperative metastasis. World J Surg (2006) 1.11
Multiple molecular markers as predictors of colorectal cancer in patients with normal perioperative serum carcinoembryonic antigen levels. Clin Cancer Res (2007) 1.10
Prognostic significance of multiple molecular markers for patients with stage II colorectal cancer undergoing curative resection. Ann Surg (2007) 1.09
A rare complication of Meckel's diverticulum: a fistula between Meckel's diverticulum and the appendix. Asian J Surg (2012) 1.06
MicroRNA-93 inhibits tumor growth and early relapse of human colorectal cancer by affecting genes involved in the cell cycle. Carcinogenesis (2012) 1.05
Persistent presence of postoperative circulating tumor cells is a poor prognostic factor for patients with stage I-III colorectal cancer after curative resection. Ann Surg Oncol (2008) 1.05
Molecular detection of APC, K- ras, and p53 mutations in the serum of colorectal cancer patients as circulating biomarkers. World J Surg (2004) 1.05
Predictive factors of early relapse in UICC stage I-III colorectal cancer patients after curative resection. J Surg Oncol (2009) 1.04
MMP13 is potentially a new tumor marker for breast cancer diagnosis. Oncol Rep (2009) 1.04
Molecular detection of circulating cancer cells in the peripheral blood of patients with colorectal cancer by using membrane array with a multiple mRNA marker panel. Int J Oncol (2006) 1.04
APC, K-ras, and p53 gene mutations in colorectal cancer patients: correlation to clinicopathologic features and postoperative surveillance. Am Surg (2005) 1.03
Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in advanced gastric carcinomas. Virchows Arch (2003) 1.03
Clinical significance of MUC1 and c-Met RT-PCR detection of circulating tumor cells in patients with gastric carcinoma. Clin Chim Acta (2006) 1.03
Enhancing detection of circulating tumor cells with activating KRAS oncogene in patients with colorectal cancer by weighted chemiluminescent membrane array method. Ann Surg Oncol (2010) 1.03
Synthesis and characterization of a new bioactivated paramagnetic gadolinium(III) complex [Gd(DOTA-FPG)(H2O)] for tracing gene expression. Bioconjug Chem (2007) 0.99
Differential expression profile of MAGE family in non-small-cell lung cancer. Lung Cancer (2007) 0.99
ZBRK1 acts as a metastatic suppressor by directly regulating MMP9 in cervical cancer. Cancer Res (2009) 0.99
The prognostic significance of total lymph node harvest in patients with T2-4N0M0 colorectal cancer. J Gastrointest Surg (2007) 0.99
ERCC2 2251A>C genetic polymorphism was highly correlated with early relapse in high-risk stage II and stage III colorectal cancer patients: a preliminary study. BMC Cancer (2008) 0.98
Development and evaluation of a colorimetric membrane-array method for the detection of circulating tumor cells in the peripheral blood of Taiwanese patients with colorectal cancer. Int J Mol Med (2006) 0.98
Comparison of breast mammography, sonography and physical examination for screening women at high risk of breast cancer in taiwan. Ultrasound Med Biol (2002) 0.95
Combination of multiple mRNA markers (PTTG1, Survivin, UbcH10 and TK1) in the diagnosis of Taiwanese patients with breast cancer by membrane array. Oncology (2007) 0.94
Successful localization and surgical removal of ingested sewing needles under mini C-arm fluoroscopy: a case report. Kaohsiung J Med Sci (2006) 0.94
Sensitive quantification of PEGylated compounds by second-generation anti-poly(ethylene glycol) monoclonal antibodies. Bioconjug Chem (2010) 0.93
Characterization of the chemical components on the surface of different solids with electrospray-assisted laser desorption ionization mass spectrometry. Rapid Commun Mass Spectrom (2007) 0.93
Significance of the glycolytic pathway and glycolysis related-genes in tumorigenesis of human colorectal cancers. Oncol Rep (2008) 0.93
Mitogen-activated protein kinase pathway was significantly activated in human bronchial epithelial cells by nicotine. DNA Cell Biol (2006) 0.92
The functional significance of microRNA-29c in patients with colorectal cancer: a potential circulating biomarker for predicting early relapse. PLoS One (2013) 0.91
Predictive value of ERCC1, ERCC2, and XRCC1 overexpression for stage III colorectal cancer patients receiving FOLFOX-4 adjuvant chemotherapy. J Surg Oncol (2013) 0.91
Hydrocele of the spermatic cord in infants and children: its particular characteristics. Urology (2010) 0.91
Development of a high-throughput membrane-array method for molecular diagnosis of circulating tumor cells in patients with gastric cancers. Int J Cancer (2006) 0.91
Gastric glomus tumor: a case report and review of the literature. Kaohsiung J Med Sci (2010) 0.91
In vivo positron emission tomography imaging of protease activity by generation of a hydrophobic product from a noninhibitory protease substrate. Clin Cancer Res (2011) 0.90
Risk factors for the development of metachronous liver metastasis in colorectal cancer patients after curative resection. World J Surg (2011) 0.90
Multiple genetic polymorphisms in the prediction of clinical outcome of metastatic colorectal cancer patients treated with first-line FOLFOX-4 chemotherapy. Pharmacogenet Genomics (2011) 0.90
Comparison of local recurrence and distant metastases between breast cancer patients after postmastectomy radiotherapy with and without immediate TRAM flap reconstruction. Plast Reconstr Surg (2006) 0.89
The inflammatory modulation effect of glutamine-enriched total parenteral nutrition in postoperative gastrointestinal cancer patients. Am Surg (2011) 0.89
A retrospective study of the safety and efficacy of a first-line treatment with modified FOLFOX-4 in unresectable advanced or recurrent gastric cancer patients. Chemotherapy (2013) 0.89
Immuno-PCR for detection of antigen to Angiostrongylus cantonensis circulating fifth-stage worms. Clin Chem (2004) 0.89
A fast and convenient new technique to detect the therapeutic target, K-ras mutant, from peripheral blood in non-small cell lung cancer patients. Lung Cancer (2009) 0.89
Gastric cancer cell detection in peritoneal lavage: RT-PCR for carcinoembryonic antigen transcripts versus the combined cytology with peritoneal carcinoembryonic antigen levels. Cancer Lett (2004) 0.89
Molecular diversity of class 1 integrons in human isolates of Aeromonas spp. from southern Taiwan. Jpn J Infect Dis (2008) 0.88
Role of MUC1 and MUC5AC expressions as prognostic indicators in gastric carcinomas. J Surg Oncol (2003) 0.88
Overexpression of S100B, TM4SF4, and OLFM4 genes is correlated with liver metastasis in Taiwanese colorectal cancer patients. DNA Cell Biol (2011) 0.88
Activation of EDTA-resistant gelatinases in malignant human tumors. Cancer Res (2006) 0.88
Transaxillary subfascial endoscopic approach for internal jugular phlebectasia in a child. Head Neck (2010) 0.88
Clinical characteristics of patients with sporadic colorectal cancer and primary cancers of other organs. Kaohsiung J Med Sci (2006) 0.88
Histamine regulates cyclooxygenase 2 gene activation through Orai1-mediated NFκB activation in lung cancer cells. Cell Calcium (2011) 0.88
A retroperitoneal gastric duplication cyst mimicking a simple exophytic renal cyst in an adolescent. J Pediatr Surg (2010) 0.88
Phosphate-modified TiO2 nanoparticles for selective detection of dopamine, levodopa, adrenaline, and catechol based on fluorescence quenching. Langmuir (2007) 0.88
Co-existence of cyclin D1 and vascular endothelial growth factor protein expression is a poor prognostic factor for UICC stage I-III colorectal cancer patients after curative resection. J Surg Oncol (2012) 0.88
Clinical significance of microRNA-148a in patients with early relapse of stage II stage and III colorectal cancer after curative resection. Transl Res (2013) 0.88
Predicting factors of postoperative relapse in T2-4N0M0 colorectal cancer patients via harvesting a minimum of 12 lymph nodes. Int J Colorectal Dis (2008) 0.87
Association between a C/T polymorphism in exon 33 of the thyroglobulin gene is associated with relapse of Graves' hyperthyroidism after antithyroid withdrawal in Taiwanese. J Clin Endocrinol Metab (2007) 0.87
Sarco/endoplasmic reticulum calcium-ATPase 2 expression as a tumor marker in colorectal cancer. Am J Surg Pathol (2006) 0.86
MMP13 is a potential prognostic marker for colorectal cancer. Oncol Rep (2010) 0.86
Comparison of clinical outcome of breast cancer patients with T1-2 tumor and one to three positive nodes with or without postmastectomy radiation therapy. Jpn J Clin Oncol (2012) 0.86