Published in J Cell Sci on August 01, 2009
Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded. Curr Biol (2010) 3.08
Epithelial cell polarity, stem cells and cancer. Nat Rev Cancer (2011) 3.06
A local autocrine axis in the testes that regulates spermatogenesis. Nat Rev Endocrinol (2010) 2.03
Molecular regulation of lumen morphogenesis. Curr Biol (2011) 1.96
Human CRB1-associated retinal degeneration: comparison with the rd8 Crb1-mutant mouse model. Invest Ophthalmol Vis Sci (2011) 1.69
Elaborating polarity: PAR proteins and the cytoskeleton. Development (2011) 1.40
An evolutionary shift in the regulation of the Hippo pathway between mice and flies. Oncogene (2013) 1.35
Formation of a Bazooka-Stardust complex is essential for plasma membrane polarity in epithelia. J Cell Biol (2010) 1.19
A genome-wide resource for the analysis of protein localisation in Drosophila. Elife (2016) 1.15
Generation of Rab-based transgenic lines for in vivo studies of endosome biology in zebrafish. Dev Dyn (2011) 1.13
Anisotropy of Crumbs and aPKC drives myosin cable assembly during tube formation. Dev Cell (2012) 1.12
Sticking together the Crumbs - an unexpected function for an old friend. Nat Rev Mol Cell Biol (2013) 1.07
Evolution of microRNAs and the diversification of species. Genome Biol Evol (2010) 1.02
Crumbs3 is essential for proper epithelial development and viability. Mol Cell Biol (2013) 1.01
The Drosophila TNF receptor Grindelwald couples loss of cell polarity and neoplastic growth. Nature (2015) 0.96
Structure of Crumbs tail in complex with the PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex. Proc Natl Acad Sci U S A (2014) 0.95
Crumbs limits oxidase-dependent signaling to maintain epithelial integrity and prevent photoreceptor cell death. J Cell Biol (2012) 0.91
Molecular Pathways: Hippo Signaling, a Critical Tumor Suppressor. Clin Cancer Res (2015) 0.90
Peripheral nerve injury is accompanied by chronic transcriptome-wide changes in the mouse prefrontal cortex. Mol Pain (2013) 0.90
Genetic ablation of Pals1 in retinal progenitor cells models the retinal pathology of Leber congenital amaurosis. Hum Mol Genet (2012) 0.90
Targeted ablation of CRB1 and CRB2 in retinal progenitor cells mimics Leber congenital amaurosis. PLoS Genet (2013) 0.89
The severity of retinal pathology in homozygous Crb1rd8/rd8 mice is dependent on additional genetic factors. Hum Mol Genet (2014) 0.88
Atypical protein kinase C controls sea urchin ciliogenesis. Mol Biol Cell (2011) 0.88
Emerging role for epithelial polarity proteins of the Crumbs family as potential tumor suppressors. J Biomed Biotechnol (2011) 0.87
Aberrant expression of the polarity complex atypical PKC and non-muscle myosin IIA in active and inactive inflammatory bowel disease. Virchows Arch (2011) 0.87
chaoptin, prominin, eyes shut and crumbs form a genetic network controlling the apical compartment of Drosophila photoreceptor cells. Biol Open (2014) 0.86
High frequency of CRB1 mutations as cause of Early-Onset Retinal Dystrophies in the Spanish population. Orphanet J Rare Dis (2013) 0.86
Structural basis for the phosphorylation-regulated interaction between the cytoplasmic tail of cell polarity protein crumbs and the actin-binding protein moesin. J Biol Chem (2015) 0.86
Correction of the Crb1rd8 allele and retinal phenotype in C57BL/6N mice via TALEN-mediated homology-directed repair. Invest Ophthalmol Vis Sci (2014) 0.86
The Scribble module regulates retromer-dependent endocytic trafficking during epithelial polarization. Development (2014) 0.86
Crumbs regulates rhodopsin transport by interacting with and stabilizing myosin V. J Cell Biol (2011) 0.85
Fosmid-based structure-function analysis reveals functionally distinct domains in the cytoplasmic domain of Drosophila crumbs. G3 (Bethesda) (2013) 0.85
Transgenic expression of constitutively active RAC1 disrupts mouse rod morphogenesis. Invest Ophthalmol Vis Sci (2014) 0.85
Modularity in protein complex and drug interactions reveals new polypharmacological properties. PLoS One (2012) 0.84
The WD40 protein Morg1 facilitates Par6-aPKC binding to Crb3 for apical identity in epithelial cells. J Cell Biol (2013) 0.84
Polarity protein Crumbs homolog-3 (CRB3) regulates ectoplasmic specialization dynamics through its action on F-actin organization in Sertoli cells. Sci Rep (2016) 0.84
The Ran importin system in cilia trafficking. Organogenesis (2011) 0.83
Drosophila PATJ supports adherens junction stability by modulating Myosin light chain activity. J Cell Biol (2012) 0.82
Structural disorganization of pronephric glomerulus in zebrafish mpp5a/nagie oko mutant. Dev Dyn (2012) 0.82
Adherens junctions in C. elegans embryonic morphogenesis. Subcell Biochem (2012) 0.81
Crumbs is an essential regulator of cytoskeletal dynamics and cell-cell adhesion during dorsal closure in Drosophila. Elife (2015) 0.81
Antagonistic functions of two stardust isoforms in Drosophila photoreceptor cells. Mol Biol Cell (2010) 0.81
Neuralized regulates Crumbs endocytosis and epithelium morphogenesis via specific Stardust isoforms. J Cell Biol (2017) 0.81
Apical deficiency triggers JNK-dependent apoptosis in the embryonic epidermis of Drosophila. Development (2011) 0.79
Epithelial cell polarity determinant CRB3 in cancer development. Int J Biol Sci (2015) 0.79
Polarity protein complex Scribble/Lgl/Dlg and epithelial cell barriers. Adv Exp Med Biol (2012) 0.79
Apical localisation of crumbs in the boundary cells of the Drosophila hindgut is independent of its canonical interaction partner stardust. PLoS One (2014) 0.79
The Ski2-family helicase Obelus regulates Crumbs alternative splicing and cell polarity. J Cell Biol (2015) 0.78
Novel neuroprotective function of apical-basal polarity gene crumbs in amyloid beta 42 (aβ42) mediated neurodegeneration. PLoS One (2013) 0.78
CRB3A Controls the Morphology and Cohesion of Cancer Cells through Ehm2/p114RhoGEF-Dependent Signaling. Mol Cell Biol (2015) 0.77
Common and distinctive localization patterns of Crumbs polarity complex proteins in the mammalian eye. Gene Expr Patterns (2015) 0.77
Epidermal polarity genes in health and disease. Cold Spring Harb Perspect Med (2014) 0.76
The transmembrane protein Crumbs displays complex dynamics during follicular morphogenesis and is regulated competitively by Moesin and aPKC. Development (2015) 0.76
The CRB1 Complex: Following the Trail of Crumbs to a Feasible Gene Therapy Strategy. Front Neurosci (2017) 0.75
Establishing the involvement of the novel gene AGBL5 in retinitis pigmentosa by whole genome sequencing. Physiol Genomics (2016) 0.75
Domain-specific functions of Stardust in Drosophila embryonic development. R Soc Open Sci (2016) 0.75
Genetic association and stress mediated down-regulation in trabecular meshwork implicates MPP7 as a novel candidate gene in primary open angle glaucoma. BMC Med Genomics (2016) 0.75
The Family of Crumbs Genes and Human Disease. Mol Syndromol (2016) 0.75
The Crumbs_C isoform of Drosophila shows tissue- and stage-specific expression and prevents light-dependent retinal degeneration. Biol Open (2017) 0.75
Fluorescently tagged Lin7c is a dynamic marker for polarity maturation in the zebrafish retinal epithelium. Biol Open (2013) 0.75
The C. elegans Crumbs family contains a CRB3 homolog and is not essential for viability. Biol Open (2015) 0.75
LIN7A is a major determinant of cell-polarity defects in breast carcinomas. Breast Cancer Res (2016) 0.75
Crumbs affects protein dynamics in anterior regions of the developing Drosophila embryo. PLoS One (2013) 0.75
Characterization of the cell polarity gene crumbs during the early development and maintenance of the squid-vibrio light organ symbiosis. Dev Genes Evol (2017) 0.75
Coordinated control of cell adhesion, polarity, and cytoskeleton underlies Hox-induced organogenesis in Drosophila. Curr Biol (2006) 2.01
Towards understanding CRUMBS function in retinal dystrophies. Hum Mol Genet (2006) 1.34
Are dendrites in Drosophila homologous to vertebrate dendrites? Dev Biol (2005) 1.26
Drosophila crumbs is required to inhibit light-induced photoreceptor degeneration. Curr Biol (2002) 1.18
Retromer controls epithelial cell polarity by trafficking the apical determinant Crumbs. Curr Biol (2011) 1.18
Crumbs stabilises epithelial polarity during tissue remodelling. J Cell Sci (2009) 1.17
DPATJ plays a role in retinal morphogenesis and protects against light-dependent degeneration of photoreceptor cells in the Drosophila eye. Dev Dyn (2006) 1.16
Computer modelling in combination with in vitro studies reveals similar binding affinities of Drosophila Crumbs for the PDZ domains of Stardust and DmPar-6. Eur J Cell Biol (2006) 1.15
Cell type-specific recruitment of Drosophila Lin-7 to distinct MAGUK-based protein complexes defines novel roles for Sdt and Dlg-S97. J Cell Sci (2004) 1.05
Unraveling the genetic complexity of Drosophila stardust during photoreceptor morphogenesis and prevention of light-induced degeneration. Genetics (2007) 1.04
IrreC/rst-mediated cell sorting during Drosophila pupal eye development depends on proper localisation of DE-cadherin. Development (2005) 1.01
A role for the extracellular domain of Crumbs in morphogenesis of Drosophila photoreceptor cells. Eur J Cell Biol (2009) 1.00
Complexities of Crumbs function and regulation in tissue morphogenesis. Curr Biol (2013) 0.94
Multiple domains of Stardust differentially mediate localisation of the Crumbs-Stardust complex during photoreceptor development in Drosophila. J Cell Sci (2008) 0.90
Drosophila Lin-7 is a component of the Crumbs complex in epithelia and photoreceptor cells and prevents light-induced retinal degeneration. Eur J Cell Biol (2008) 0.89
The use of P-element transposons to generate transgenic flies. Methods Mol Biol (2008) 0.87
Analysis of the Drosophila compound eye with light and electron microscopy. Methods Mol Biol (2013) 0.86
Isoform-specific interaction of Flamingo/Starry Night with excess Bazooka affects planar cell polarity in the Drosophila wing. Dev Dyn (2007) 0.86
A perisynaptic ménage à trois between Dlg, DLin-7, and Metro controls proper organization of Drosophila synaptic junctions. J Neurosci (2010) 0.86
On the role of the MAGUK proteins encoded by Drosophila varicose during embryonic and postembryonic development. BMC Dev Biol (2008) 0.86
Crumbs regulates rhodopsin transport by interacting with and stabilizing myosin V. J Cell Biol (2011) 0.85
Fosmid-based structure-function analysis reveals functionally distinct domains in the cytoplasmic domain of Drosophila crumbs. G3 (Bethesda) (2013) 0.85
Increased levels of the cytoplasmic domain of Crumbs repolarise developing Drosophila photoreceptors. J Cell Sci (2011) 0.84
Antagonistic functions of two stardust isoforms in Drosophila photoreceptor cells. Mol Biol Cell (2010) 0.81
The Drosophila Crumbs signal peptide is unusually long and is a substrate for signal peptide peptidase. Eur J Cell Biol (2010) 0.80
Prominent role of prominin in the retina. Adv Exp Med Biol (2013) 0.80
DLin-7 is required in postsynaptic lamina neurons to prevent light-induced photoreceptor degeneration in Drosophila. Curr Biol (2013) 0.78
Crumbs regulates polarity and prevents light-induced degeneration of the simple eyes of Drosophila, the ocelli. Eur J Cell Biol (2012) 0.77
Targeting of Drosophila rhodopsin requires helix 8 but not the distal C-terminus. PLoS One (2009) 0.76
Crumbs affects protein dynamics in anterior regions of the developing Drosophila embryo. PLoS One (2013) 0.75
Fluorescently tagged Lin7c is a dynamic marker for polarity maturation in the zebrafish retinal epithelium. Biol Open (2013) 0.75
An interview with Elisabeth Knust: President of the German Society for Developmental Biology. Interview by Eva Amsen. Development (2011) 0.75