Published in Curr Biol on April 01, 2010
The hippo signaling pathway in development and cancer. Dev Cell (2010) 10.54
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Yap1 acts downstream of α-catenin to control epidermal proliferation. Cell (2011) 4.85
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The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals. Dev Cell (2010) 4.47
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Epithelial cell polarity, stem cells and cancer. Nat Rev Cancer (2011) 3.06
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Modulating F-actin organization induces organ growth by affecting the Hippo pathway. EMBO J (2011) 2.75
E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components. Proc Natl Acad Sci U S A (2011) 2.61
The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded. Proc Natl Acad Sci U S A (2010) 2.43
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The Hippo pathway regulates intestinal stem cell proliferation during Drosophila adult midgut regeneration. Development (2010) 1.93
Polarity-dependent distribution of angiomotin localizes Hippo signaling in preimplantation embryos. Curr Biol (2013) 1.86
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The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex. Dev Cell (2010) 1.67
Regulation of Hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1. Proc Natl Acad Sci U S A (2013) 1.59
KIBRA regulates Hippo signaling activity via interactions with large tumor suppressor kinases. J Biol Chem (2011) 1.50
Organ size control by Hippo and TOR pathways. Curr Biol (2012) 1.45
Scaling the Drosophila Wing: TOR-Dependent Target Gene Access by the Hippo Pathway Transducer Yorkie. PLoS Biol (2015) 1.45
Tao-1 phosphorylates Hippo/MST kinases to regulate the Hippo-Salvador-Warts tumor suppressor pathway. Dev Cell (2011) 1.43
Salvador-Warts-Hippo pathway in a developmental checkpoint monitoring helix-loop-helix proteins. Dev Cell (2015) 1.42
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An evolutionary shift in the regulation of the Hippo pathway between mice and flies. Oncogene (2013) 1.35
The Hippo-YAP signaling pathway and contact inhibition of growth. J Cell Sci (2014) 1.29
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Growth control by committee: intercellular junctions, cell polarity, and the cytoskeleton regulate Hippo signaling. Dev Cell (2012) 1.26
Protein complexes that control renal epithelial polarity. Am J Physiol Renal Physiol (2011) 1.22
Regulation of Drosophila glial cell proliferation by Merlin-Hippo signaling. Development (2011) 1.19
Cell competition: how to eliminate your neighbours. Development (2014) 1.17
The cell adhesion molecule echinoid functions as a tumor suppressor and upstream regulator of the Hippo signaling pathway. Dev Cell (2012) 1.16
Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling. BMC Dev Biol (2011) 1.15
Integration of intercellular signaling through the Hippo pathway. Semin Cell Dev Biol (2012) 1.14
Hippo signaling at a glance. J Cell Sci (2010) 1.14
Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1. Mol Syst Biol (2013) 1.10
Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila. Nat Cell Biol (2013) 1.08
Sticking together the Crumbs - an unexpected function for an old friend. Nat Rev Mol Cell Biol (2013) 1.07
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Crumbs3 is essential for proper epithelial development and viability. Mol Cell Biol (2013) 1.01
The role of the Hippo pathway in human disease and tumorigenesis. Clin Transl Med (2014) 0.99
The Drosophila TNF receptor Grindelwald couples loss of cell polarity and neoplastic growth. Nature (2015) 0.96
The Drosophila ortholog of MLL3 and MLL4, trithorax related, functions as a negative regulator of tissue growth. Mol Cell Biol (2013) 0.96
Binary regulation of Hippo pathway by Merlin/NF2, Kibra, Lgl, and Melted specifies and maintains postmitotic neuronal fate. Dev Cell (2011) 0.95
Organ Size Control: Lessons from Drosophila. Dev Cell (2015) 0.95
A screen for conditional growth suppressor genes identifies the Drosophila homolog of HD-PTP as a regulator of the oncoprotein Yorkie. Dev Cell (2011) 0.94
Differences in levels of the transmembrane protein Crumbs can influence cell survival at clonal boundaries. Dev Biol (2012) 0.94
Signaling pathways in cell polarity. Cold Spring Harb Perspect Biol (2012) 0.92
Control of organ growth by patterning and hippo signaling in Drosophila. Cold Spring Harb Perspect Biol (2015) 0.92
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Par-1 regulates tissue growth by influencing hippo phosphorylation status and hippo-salvador association. PLoS Biol (2013) 0.92
Riquiqui and minibrain are regulators of the hippo pathway downstream of Dachsous. Nat Cell Biol (2013) 0.91
Differential regulation of the Hippo pathway by adherens junctions and apical-basal cell polarity modules. Proc Natl Acad Sci U S A (2015) 0.89
Targeted ablation of CRB1 and CRB2 in retinal progenitor cells mimics Leber congenital amaurosis. PLoS Genet (2013) 0.89
The transcriptional response to tumorigenic polarity loss in Drosophila. Elife (2015) 0.89
Scribble acts in the Drosophila fat-hippo pathway to regulate warts activity. PLoS One (2012) 0.89
Cell density sensing alters TGF-β signaling in a cell-type-specific manner, independent from Hippo pathway activation. Dev Cell (2015) 0.88
The Hippo signalling pathway maintains quiescence in Drosophila neural stem cells. Nat Commun (2016) 0.88
Crumbs3-Mediated Polarity Directs Airway Epithelial Cell Fate through the Hippo Pathway Effector Yap. Dev Cell (2015) 0.88
The Mammalian Blood-Testis Barrier: Its Biology and Regulation. Endocr Rev (2015) 0.88
Cellular Organization and Cytoskeletal Regulation of the Hippo Signaling Network. Trends Cell Biol (2016) 0.88
The Spectrin cytoskeleton regulates the Hippo signalling pathway. EMBO J (2015) 0.87
Emerging role for epithelial polarity proteins of the Crumbs family as potential tumor suppressors. J Biomed Biotechnol (2011) 0.87
Regulation and function of the TAZ transcription co-activator. Int J Biochem Mol Biol (2011) 0.87
The Hippo pathway regulates stem cell proliferation, self-renewal, and differentiation. Protein Cell (2012) 0.86
Structural basis for the phosphorylation-regulated interaction between the cytoplasmic tail of cell polarity protein crumbs and the actin-binding protein moesin. J Biol Chem (2015) 0.86
YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation. PLoS One (2012) 0.85
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The protein O-glucosyltransferase Rumi modifies eyes shut to promote rhabdomere separation in Drosophila. PLoS Genet (2014) 0.84
Drosophila PI4KIIIalpha is required in follicle cells for oocyte polarization and Hippo signaling. Development (2011) 0.84
Establishment of epithelial polarity--GEF who's minding the GAP? J Cell Sci (2014) 0.84
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The ecdysone receptor coactivator Taiman links Yorkie to transcriptional control of germline stem cell factors in somatic tissue. Dev Cell (2015) 0.83
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Microarray and morphological analysis of early postnatal CRB2 mutant retinas on a pure C57BL/6J genetic background. PLoS One (2013) 0.82
SCF(Slmb) E3 ligase-mediated degradation of Expanded is inhibited by the Hippo pathway in Drosophila. Cell Res (2014) 0.82
The Hippo pathway regulates homeostatic growth of stem cell niche precursors in the Drosophila ovary. PLoS Genet (2015) 0.81
Hippo signalling controls Dronc activity to regulate organ size in Drosophila. Cell Death Differ (2012) 0.81
Crumbs is an essential regulator of cytoskeletal dynamics and cell-cell adhesion during dorsal closure in Drosophila. Elife (2015) 0.81
Arhgef7 promotes activation of the Hippo pathway core kinase Lats. EMBO J (2014) 0.81
Crumbs promotes expanded recognition and degradation by the SCF(Slimb/β-TrCP) ubiquitin ligase. Proc Natl Acad Sci U S A (2014) 0.81
Localization of Hippo signalling complexes and Warts activation in vivo. Nat Commun (2015) 0.81
Antagonistic functions of two stardust isoforms in Drosophila photoreceptor cells. Mol Biol Cell (2010) 0.81
PML Surfs into HIPPO Tumor Suppressor Pathway. Front Oncol (2013) 0.80
Rabaptin-5 and Rabex-5 are neoplastic tumour suppressor genes that interact to modulate Rab5 dynamics in Drosophila melanogaster. Dev Biol (2013) 0.80
Snapshots of a hybrid transcription factor in the Hippo pathway. Protein Cell (2010) 0.80
Histone acetylation-mediated regulation of the Hippo pathway. PLoS One (2013) 0.80
Redemystifying MST1/hippo signaling. Protein Cell (2010) 0.79
Epithelial cell polarity determinant CRB3 in cancer development. Int J Biol Sci (2015) 0.79
The Hippo signaling pathway provides novel anti-cancer drug targets. Oncotarget (2016) 0.79
Loss of the tumor suppressor Pten promotes proliferation of Drosophila melanogaster cells in vitro and gives rise to continuous cell lines. PLoS One (2012) 0.78
Novel neuroprotective function of apical-basal polarity gene crumbs in amyloid beta 42 (aβ42) mediated neurodegeneration. PLoS One (2013) 0.78
Bazooka/PAR3 is dispensable for polarity in Drosophila follicular epithelial cells. Biol Open (2015) 0.77
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The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis. Nat Cell Biol (2005) 6.74
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Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion. Genes Dev (1994) 5.71
The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway. Dev Cell (2008) 5.58
Expression of crumbs confers apical character on plasma membrane domains of ectodermal epithelia of Drosophila. Cell (1995) 4.10
Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors. Genes Dev (2004) 3.86
The tumor-suppressor gene fat controls tissue growth upstream of expanded in the hippo signaling pathway. Curr Biol (2006) 3.83
crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia. Cell (1990) 3.79
Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway. Curr Biol (2006) 3.72
Crumbs, the Drosophila homologue of human CRB1/RP12, is essential for photoreceptor morphogenesis. Nature (2002) 3.22
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Morphogen control of wing growth through the Fat signaling pathway. Dev Cell (2008) 2.80
Mutations in erupted, the Drosophila ortholog of mammalian tumor susceptibility gene 101, elicit non-cell-autonomous overgrowth. Dev Cell (2005) 2.57
The FERM-domain protein Expanded regulates Hippo pathway activity via direct interactions with the transcriptional activator Yorkie. Dev Cell (2009) 2.53
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Salvador-warts-hippo signaling promotes Drosophila posterior follicle cell maturation downstream of notch. Curr Biol (2007) 1.75
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The FERM protein Yurt is a negative regulatory component of the Crumbs complex that controls epithelial polarity and apical membrane size. Dev Cell (2006) 1.67
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Moesin contributes an essential structural role in Drosophila photoreceptor morphogenesis. Development (2004) 1.64
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Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development. Proc Natl Acad Sci U S A (2009) 1.57
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Basolateral junctions utilize warts signaling to control epithelial-mesenchymal transition and proliferation crucial for migration and invasion of Drosophila ovarian epithelial cells. Genetics (2008) 1.21
The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growth. J Cell Sci (2009) 1.20
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The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded. Proc Natl Acad Sci U S A (2010) 2.43
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Cloning, expression and characterization of protein disulfide isomerase of Schistosoma japonicum. Exp Parasitol (2014) 0.79
Molecular cloning and characterization of glutamine synthetase, a tegumental protein from Schistosoma japonicum. Parasitol Res (2012) 0.79
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Characterization of Schistosoma japonicum estrogen-related receptor beta like 1 and immunogenicity analysis of the recombinant protein. Exp Parasitol (2012) 0.77
The archipelago ubiquitin ligase subunit acts in target tissue to restrict tracheal terminal cell branching and hypoxic-induced gene expression. PLoS Genet (2013) 0.77
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Characterization Analysis of Schistosoma japonicum Plasma Membrane Repair Relative Gene Myoferlin. PLoS One (2013) 0.77
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Gene gun bombardment with DNA-coated golden particles enhanced the protective effect of a DNA vaccine based on thioredoxin glutathione reductase of Schistosoma japonicum. Biomed Res Int (2012) 0.76
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A retinoid X receptor (RXR1) homolog from Schistosoma japonicum: its ligand-binding domain may bind to 9-cis-retinoic acid. Mol Biochem Parasitol (2013) 0.76
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Experimental investigation of multi-band OCT precoding for OFDM-based visible light communications. Opt Express (2017) 0.75
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Cloning, expression, and preliminary characterization of the dysferlin tegument protein in Schistosoma japonicum. Parasitol Int (2013) 0.75
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[Screening and verification on characteristic differentially expressed genes of Schistosoma japonicum from three reservoir hosts]. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi (2012) 0.75
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