Published in BMC Mol Biol on July 28, 2009
Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels. FASEB J (2013) 2.16
MiR-221/-222 differentiate prognostic groups in advanced breast cancers and influence cell invasion. Br J Cancer (2013) 0.91
PLAUR polymorphisms and lung function in UK smokers. BMC Med Genet (2009) 0.91
Urokinase receptor orchestrates the plasminogen system in airway epithelial cell function. Lung (2013) 0.86
Putting the Squeeze on Airway Epithelia. Physiology (Bethesda) (2015) 0.86
Leukotriene B4 receptor locus gene characterisation and association studies in asthma. BMC Med Genet (2012) 0.79
Secreted uPAR isoform 2 (uPAR7b) is a novel direct target of miR-221. Oncotarget (2015) 0.77
uPAR: a versatile signalling orchestrator. Nat Rev Mol Cell Biol (2002) 6.24
Regulation of integrin function by the urokinase receptor. Science (1996) 3.56
Gene expression profiling in patients with chronic obstructive pulmonary disease and lung cancer. Am J Respir Crit Care Med (2007) 2.39
Epithelium dysfunction in asthma. J Allergy Clin Immunol (2007) 2.20
Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide. EMBO J (2005) 2.12
Structure-function relationships in the receptor for urokinase-type plasminogen activator. Comparison to other members of the Ly-6 family and snake venom alpha-neurotoxins. FEBS Lett (1994) 1.88
Role of transcription factors in inflammatory lung diseases. Thorax (1998) 1.85
Involvement of the urokinase-type plasminogen activator receptor in hematopoietic stem cell mobilization. Blood (2004) 1.83
Expression of integrins and basement membrane components by wound keratinocytes. J Clin Invest (1993) 1.80
The plasminogen (fibrinolytic) system. Thromb Haemost (1999) 1.54
Urokinase receptor: a molecular organizer in cellular communication. Curr Opin Cell Biol (2000) 1.52
A urokinase-sensitive region of the human urokinase receptor is responsible for its chemotactic activity. EMBO J (1997) 1.47
Sputum cathelicidin, urokinase plasminogen activation system components, and cytokines discriminate cystic fibrosis, COPD, and asthma inflammation. Chest (2005) 1.44
Clinical relevance of airway remodelling in airway diseases. Eur Respir J (2007) 1.44
Urokinase plasminogen activator receptor choreographs multiple ligand interactions: implications for tumor progression and therapy. Clin Cancer Res (2008) 1.40
A region in urokinase plasminogen receptor domain III controlling a functional association with alpha5beta1 integrin and tumor growth. J Biol Chem (2006) 1.38
Domain 2 of the urokinase receptor contains an integrin-interacting epitope with intrinsic signaling activity: generation of a new integrin inhibitor. J Biol Chem (2005) 1.33
Functions of pulmonary epithelial integrins: from development to disease. Physiol Rev (2003) 1.29
Transcription factors and asthma. Eur Respir J (1998) 1.23
Protease crosstalk with integrins: the urokinase receptor paradigm. Thromb Haemost (2001) 1.23
Characterization of the functional epitope on the urokinase receptor. Complete alanine scanning mutagenesis supplemented by chemical cross-linking. J Biol Chem (2006) 1.23
Urokinase receptor cleavage: a crucial step in fibroblast-to-myofibroblast differentiation. Mol Biol Cell (2007) 1.20
Glucocorticoids increase repair potential in a novel in vitro human airway epithelial wounding model. J Clin Immunol (2006) 1.13
Urokinase-type plasminogen activator. Int J Biochem Cell Biol (2006) 1.06
Induction of the plasminogen activator system by mechanical stimulation of human bronchial epithelial cells. Am J Respir Cell Mol Biol (2006) 1.04
Requirement of an upstream AP-1 motif for the constitutive and phorbol ester-inducible expression of the urokinase-type plasminogen activator receptor gene. J Biol Chem (1996) 1.04
PLAUR polymorphisms are associated with asthma, PLAUR levels, and lung function decline. J Allergy Clin Immunol (2009) 1.04
The plasmin system in airway remodeling. Thromb Res (2003) 1.01
The structure of the urokinase-type plasminogen activator receptor gene. Blood (1994) 0.99
Urokinase induces expression of its own receptor in Beas2B lung epithelial cells. J Biol Chem (2001) 0.98
Glycosylation profile of a recombinant urokinase-type plasminogen activator receptor expressed in Chinese hamster ovary cells. J Biol Chem (1998) 0.98
An alternatively spliced variant of mRNA for the human receptor for urokinase plasminogen activator. FEBS Lett (1993) 0.97
The human airway trypsin-like protease modulates the urokinase receptor (uPAR, CD87) structure and functions. Am J Physiol Lung Cell Mol Physiol (2007) 0.95
Identification of a novel urokinase receptor splice variant and its prognostic relevance in breast cancer. Thromb Haemost (2003) 0.93
Urokinase receptor variants in tissue and body fluids. Adv Clin Chem (2007) 0.93
A conserved TATA-less proximal promoter drives basal transcription from the urokinase-type plasminogen activator receptor gene. Blood (1995) 0.93
Urokinase-type plasminogen activator modulates airway eosinophil adhesion in asthma. Am J Respir Cell Mol Biol (2006) 0.91
Requirement of TGF-beta receptor-dependent activation of c-Jun N-terminal kinases (JNKs)/stress-activated protein kinases (Sapks) for TGF-beta up-regulation of the urokinase-type plasminogen activator receptor. J Cell Physiol (2004) 0.90
A region between -141 and -61 bp containing a proximal AP-1 is essential for constitutive expression of urokinase-type plasminogen activator receptor. Eur J Biochem (1999) 0.89
Salmeterol and cytokines modulate inositol-phosphate signalling in human airway smooth muscle cells via regulation at the receptor locus. Respir Res (2007) 0.85
Ligand binding regions in the receptor for urokinase-type plasminogen activator. J Biol Chem (2001) 0.78
Genome-wide association study identifies five loci associated with lung function. Nat Genet (2009) 4.10
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet (2011) 3.03
Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels. FASEB J (2013) 2.16
Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function. Am J Respir Crit Care Med (2011) 2.07
Beta2-adrenoceptor polymorphisms and asthma from childhood to middle age in the British 1958 birth cohort: a genetic association study. Lancet (2006) 1.84
IL-33 is more potent than IL-25 in provoking IL-13-producing nuocytes (type 2 innate lymphoid cells) and airway contraction. J Allergy Clin Immunol (2013) 1.70
Evaluation of differentiated human bronchial epithelial cell culture systems for asthma research. J Allergy (Cairo) (2012) 1.39
Meta-analysis of genome-wide linkage studies of asthma and related traits. Respir Res (2008) 1.16
A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample. PLoS One (2011) 1.13
PLAUR polymorphisms are associated with asthma, PLAUR levels, and lung function decline. J Allergy Clin Immunol (2009) 1.04
uPAR regulates bronchial epithelial repair in vitro and is elevated in asthmatic epithelium. Thorax (2011) 1.01
GSTCD and INTS12 regulation and expression in the human lung. PLoS One (2013) 0.94
PLAUR polymorphisms and lung function in UK smokers. BMC Med Genet (2009) 0.91
Urokinase receptor orchestrates the plasminogen system in airway epithelial cell function. Lung (2013) 0.86
Salmeterol and cytokines modulate inositol-phosphate signalling in human airway smooth muscle cells via regulation at the receptor locus. Respir Res (2007) 0.85
Characterization of protocadherin-1 expression in primary bronchial epithelial cells: association with epithelial cell differentiation. FASEB J (2011) 0.85
Genetic basis for personalized medicine in asthma. Expert Rev Respir Med (2012) 0.84
Evidence of a genetic contribution to lung function decline in asthma. J Allergy Clin Immunol (2011) 0.83
HTR4 gene structure and altered expression in the developing lung. Respir Res (2013) 0.83
A genome-wide association study to identify genetic determinants of atopy in subjects from the United Kingdom. J Allergy Clin Immunol (2010) 0.81
Alternative promoter use and splice variation in the human histamine H1 receptor gene. Am J Respir Cell Mol Biol (2006) 0.81
Can lineage-specific markers be identified to characterize mesenchyme-derived cell populations in the human airways? Am J Physiol Lung Cell Mol Physiol (2010) 0.80
The role of ALOX5AP, LTA4H and LTB4R polymorphisms in determining baseline lung function and COPD susceptibility in UK smokers. BMC Med Genet (2011) 0.79
Leukotriene B4 receptor locus gene characterisation and association studies in asthma. BMC Med Genet (2012) 0.79
Defining the contribution of SNPs identified in asthma GWAS to clinical variables in asthmatic children. BMC Med Genet (2013) 0.79
Functional polymorphism and differential regulation of CYSLTR1 transcription in human airway smooth muscle and monocytes. Cell Biochem Biophys (2007) 0.77
Response. FASEB J (2015) 0.75
Clonally expanded human airway smooth muscle cells exhibit morphological and functional heterogeneity. Respir Res (2014) 0.75
Effects of atopy and grass pollen season on histamine H₄ receptor expression in human leukocytes. Ann Allergy Asthma Immunol (2013) 0.75