Published in Bioessays on September 01, 2009
Where genotype is not predictive of phenotype: towards an understanding of the molecular basis of reduced penetrance in human inherited disease. Hum Genet (2013) 2.44
Modulation of mismatch repair and genomic stability by miR-155. Proc Natl Acad Sci U S A (2010) 2.05
CNOT3 is a modifier of PRPF31 mutations in retinitis pigmentosa with incomplete penetrance. PLoS Genet (2012) 1.24
miR-34 is maternally inherited in Drosophila melanogaster and Danio rerio. Nucleic Acids Res (2013) 0.89
Changes in micro RNA expression in a wild tuber-bearing Solanum species induced by 5-Azacytidine treatment. Plant Cell Rep (2012) 0.85
Interrelationship between microsatellite instability and microRNA in gastrointestinal cancer. World J Gastroenterol (2012) 0.84
[Pathobiology of the microRNA system]. Pathologe (2012) 0.80
Changing genetic paradigms: creating next-generation genetic databases as tools to understand the emerging complexities of genotype/phenotype relationships. Hum Genomics (2014) 0.79
A novel mechanism for variable phenotypic expressivity in Mendelian diseases uncovered by an AU-rich element (ARE)-creating mutation. Genome Biol (2017) 0.75
The screening of the functional microRNA binding site SNPs in sporadic colorectal cancer genes. Cancer Biol Ther (2017) 0.75
Personal omics profiling reveals dynamic molecular and medical phenotypes. Cell (2012) 12.32
Annotation of functional variation in personal genomes using RegulomeDB. Genome Res (2012) 11.47
Variation in transcription factor binding among humans. Science (2010) 9.33
An encyclopedia of mouse DNA elements (Mouse ENCODE). Genome Biol (2012) 4.15
Comprehensive expression analyses of neural cell-type-specific miRNAs identify new determinants of the specification and maintenance of neuronal phenotypes. J Neurosci (2013) 2.08
Targets for human encoded microRNAs in HIV genes. Biochem Biophys Res Commun (2005) 1.99
Host-virus interaction: a new role for microRNAs. Retrovirology (2006) 1.88
Human cellular microRNA hsa-miR-29a interferes with viral nef protein expression and HIV-1 replication. Retrovirology (2008) 1.87
High-throughput sequencing for biology and medicine. Mol Syst Biol (2013) 1.75
Posttranscriptional regulation of interleukin-10 expression by hsa-miR-106a. Proc Natl Acad Sci U S A (2009) 1.64
Upregulation of miR-23a-27a-24-2 cluster induces caspase-dependent and -independent apoptosis in human embryonic kidney cells. PLoS One (2009) 1.54
Detection of altered global DNA methylation in coronary artery disease patients. DNA Cell Biol (2008) 1.50
Application of SNaPshot for analysis of thiopurine methyltransferase gene polymorphism. Indian J Med Res (2009) 1.44
Molecular effects of uptake of gold nanoparticles in HeLa cells. Chembiochem (2007) 1.37
Inhibition of translation in living eukaryotic cells by an RNA G-quadruplex motif. RNA (2008) 1.34
Host-virus genome interactions: macro roles for microRNAs. Cell Microbiol (2007) 1.28
Consensus miRNA expression profiles derived from interplatform normalization of microarray data. RNA (2009) 1.27
Quadfinder: server for identification and analysis of quadruplex-forming motifs in nucleotide sequences. Nucleic Acids Res (2006) 1.26
Mining literature for a comprehensive pathway analysis: a case study for retrieval of homocysteine related genes for genetic and epigenetic studies. Lipids Health Dis (2006) 1.25
MicroRNA-mediated up-regulation of an alternatively polyadenylated variant of the mouse cytoplasmic {beta}-actin gene. Nucleic Acids Res (2008) 1.25
Tcf7 is an important regulator of the switch of self-renewal and differentiation in a multipotential hematopoietic cell line. PLoS Genet (2012) 1.14
Comparative analysis of chromatin landscape in regulatory regions of human housekeeping and tissue specific genes. BMC Bioinformatics (2005) 1.13
Analysis of expression profile of mammalian cell entry (mce) operons of Mycobacterium tuberculosis. Infect Immun (2003) 1.11
Comparison of mammalian cell entry operons of mycobacteria: in silico analysis and expression profiling. FEMS Immunol Med Microbiol (2005) 1.11
MicroRNAs: novel therapeutic targets in neurodegenerative diseases. Drug Discov Today (2009) 1.09
Epigenetic regulation of cytomegalovirus major immediate-early promoter activity in transgenic mice. Gene (2008) 1.07
Homocysteine- and cysteine-mediated growth defect is not associated with induction of oxidative stress response genes in yeast. Biochem J (2006) 1.04
Differential serum cytokine levels are associated with cytokine gene polymorphisms in north Indians with active pulmonary tuberculosis. Infect Genet Evol (2011) 0.99
Genomic analysis of local isolate of Mycobacterium avium subspecies paratuberculosis. Vet Microbiol (2008) 0.95
Regulation of BACE1 by miR-29a/b in a cellular model of Spinocerebellar Ataxia 17. RNA Biol (2012) 0.93
A role for voltage-dependent anion channel Vdac1 in polyglutamine-mediated neuronal cell death. PLoS One (2007) 0.91
Identification of novel targets for miR-29a using miRNA proteomics. PLoS One (2012) 0.90
miR-34 is maternally inherited in Drosophila melanogaster and Danio rerio. Nucleic Acids Res (2013) 0.89
Characterization of Mce4A protein of Mycobacterium tuberculosis: role in invasion and survival. BMC Microbiol (2008) 0.88
Genome-wide analysis reveals downregulation of miR-379/miR-656 cluster in human cancers. Biol Direct (2013) 0.88
Proximity of H2A.Z containing nucleosome to the transcription start site influences gene expression levels in the mammalian liver and brain. Nucleic Acids Res (2012) 0.88
Characterization of a human SWI2/SNF2 like protein hINO80: demonstration of catalytic and DNA binding activity. Biochem Biophys Res Commun (2005) 0.88
GASCO: genetic algorithm simulation for codon optimization. In Silico Biol (2008) 0.87
Inhibition of neuronal cholesterol biosynthesis with lovastatin leads to impaired synaptic vesicle release even in the presence of lipoproteins or geranylgeraniol. J Neurochem (2011) 0.87
Chromatin remodeling protein INO80 has a role in regulation of homeotic gene expression in Drosophila. Genes Cells (2010) 0.85
In silico characterization of the INO80 subfamily of SWI2/SNF2 chromatin remodeling proteins. Biochem Biophys Res Commun (2004) 0.83
Nucleosomal occupancy and CGG repeat expansion: a comparative analysis of triplet repeat region from mouse and human fragile X mental retardation gene 1. Chromosome Res (2011) 0.82
Functional analysis of an intergenic non-coding sequence within mce1 operon of M.tuberculosis. BMC Microbiol (2010) 0.81
DyNAVacS: an integrative tool for optimized DNA vaccine design. Nucleic Acids Res (2006) 0.81
Genome-wide expression profile of steroid response in Saccharomyces cerevisiae. Biochem Biophys Res Commun (2004) 0.81
Identification and Validation of a Putative Polycomb Responsive Element in the Human Genome. PLoS One (2013) 0.80
Loss of kinase activity in Mycobacterium tuberculosis multidomain protein Rv1364c. FEBS J (2008) 0.80
Cigarette smoke extract induces changes in growth and gene expression of Saccharomyces cerevisiae. Biochem Biophys Res Commun (2005) 0.79
Single nucleotide polymorphism in the genes of mce1 and mce4 operons of Mycobacterium tuberculosis: analysis of clinical isolates and standard reference strains. BMC Microbiol (2011) 0.79
Instability of CGG repeats in transgenic mice. Genomics (2002) 0.78
Mining of putative cis-acting elements for chromatin mediated regulation of Hox genes in mammals by in-silico analysis. J Exp Zool B Mol Dev Evol (2007) 0.78
Domainal organization of the lower eukaryotic homologs of the yeast RNA polymerase II core subunit Rpb7 reflects functional conservation. Nucleic Acids Res (2004) 0.78
A whole genome analysis of 5' regulatory regions of human genes for putative cis-acting modulators of nucleosome positioning. Gene (2007) 0.78
Targeted activation of transcription in vivo through hairpin-triplex forming oligonucleotide in Saccharomyces cerevisiae. Mol Cell Biochem (2005) 0.78
microRNA: an emerging therapeutic. ChemMedChem (2007) 0.78
Modeling SNP mediated differential targeting of homologous 3'UTR by microRNA. RNA Biol (2012) 0.77
Magnetite (Fe3O4) nanocrystals affect the expression of genes involved in the TGF-beta signalling pathway. Mol Biosyst (2011) 0.77
Hsp90-targeted miRNA-liposomal formulation for systemic antitumor effect. Biomaterials (2013) 0.77
Corrigendum: Human body epigenome maps reveal noncanonical DNA methylation variation. Nature (2015) 0.77
A study on the influence of different promoter and 5'UTR (URM) cassettes from Arabidopsis thaliana on the expression level of the reporter gene β glucuronidase in tobacco and cotton. Transgenic Res (2013) 0.76
Relative levels of RNA polII subunits differentially affect starvation response in budding yeast. Biochem Biophys Res Commun (2007) 0.76
Tat predominantly associates with host promoter elements in HIV-1-infected T-cells - regulatory basis of transcriptional repression of c-Rel. FEBS J (2014) 0.75
A kinetic model of TBP auto-regulation exhibits bistability. Biol Direct (2010) 0.75
A simple method for incorporating dynamic effects of intronic miRNA mediated regulation. Mol Biosyst (2012) 0.75
Design and structural analysis of hairpin-TFO for transcriptional activation of genes in S. cerevisiae. J Biomol Struct Dyn (2002) 0.75
Detection and knockdown of microRNA-34a using thioacetamido nucleic acid. Nucleic Acid Ther (2013) 0.75
The Mycobacterium tuberculosis recombinant LprN protein of mce4 operon induces Th-1 type response deleterious to protection in mice. Pathog Dis (2014) 0.75