Published in Proc Natl Acad Sci U S A on March 23, 2009
The regulation of IL-10 production by immune cells. Nat Rev Immunol (2010) 9.18
Physiological and pathological roles for microRNAs in the immune system. Nat Rev Immunol (2010) 7.75
Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21. Nat Immunol (2009) 5.05
miR-30b/30d regulation of GalNAc transferases enhances invasion and immunosuppression during metastasis. Cancer Cell (2011) 2.30
microRNAs and the immune response. Curr Opin Pharmacol (2009) 2.18
Analysis of the host microRNA response to Salmonella uncovers the control of major cytokines by the let-7 family. EMBO J (2011) 2.03
Functional microRNA is transferred between glioma cells. Cancer Res (2010) 1.63
MicroRNA regulation of IFN-beta protein expression: rapid and sensitive modulation of the innate immune response. J Immunol (2010) 1.61
Role of interleukin 10 transcriptional regulation in inflammation and autoimmune disease. Crit Rev Immunol (2012) 1.49
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Interferon-dependent IL-10 production by Tregs limits tumor Th17 inflammation. J Clin Invest (2013) 1.21
MicroRNA regulation of molecular networks mapped by global microRNA, mRNA, and protein expression in activated T lymphocytes. J Immunol (2011) 1.18
Interleukin-10 and immunity against prokaryotic and eukaryotic intracellular pathogens. Infect Immun (2011) 1.16
Diagnostic, functional, and therapeutic roles of microRNA in allergic diseases. J Allergy Clin Immunol (2013) 1.11
MicroRNAs: new regulators of Toll-like receptor signalling pathways. Biomed Res Int (2014) 1.11
Posttranscriptional silencing of effector cytokine mRNA underlies the anergic phenotype of self-reactive T cells. Immunity (2011) 1.07
The emerging role of miRNAs in inflammatory bowel disease: a review. Therap Adv Gastroenterol (2015) 1.03
RNA-binding protein AUF1 regulates lipopolysaccharide-induced IL10 expression by activating IkappaB kinase complex in monocytes. Mol Cell Biol (2010) 1.00
The therapeutic potential of interleukin-10 in neuroimmune diseases. Neuropharmacology (2014) 0.98
MicroRNA dysregulation in the spinal cord following traumatic injury. PLoS One (2012) 0.98
Role of microRNAs in gastric cancer. World J Gastroenterol (2014) 0.98
Immune modulatory function of abundant immune-related microRNAs in microvesicles from bovine colostrum. Protein Cell (2013) 0.97
MicroRNAs and toll-like receptor/interleukin-1 receptor signaling. J Hematol Oncol (2012) 0.95
Crucial role for early growth response-1 in the transcriptional regulation of miR-20b in breast cancer. Oncotarget (2013) 0.94
Characterization of microRNA expression profiles and the discovery of novel microRNAs involved in cancer during human embryonic development. PLoS One (2013) 0.93
MicroRNAs in the regulation of TLR and RIG-I pathways. Cell Mol Immunol (2012) 0.92
MicroRNA dysregulation in spinal cord injury: causes, consequences and therapeutics. Front Cell Neurosci (2014) 0.91
microRNA-mediated regulation of innate immune response in rheumatic diseases. Arthritis Res Ther (2013) 0.91
MicroRNA control in the development of systemic autoimmunity. Arthritis Res Ther (2013) 0.91
MicroRNA let-7e is associated with the pathogenesis of experimental autoimmune encephalomyelitis. Eur J Immunol (2012) 0.89
Differential responses of disease-resistant and disease-susceptible primate macrophages and myeloid dendritic cells to simian hemorrhagic fever virus infection. J Virol (2013) 0.85
Targeting MicroRNA Function in Respiratory Diseases: Mini-Review. Front Physiol (2016) 0.85
miR-106b fine tunes ATG16L1 expression and autophagic activity in intestinal epithelial HCT116 cells. Inflamm Bowel Dis (2013) 0.84
Genetics of asthma: a molecular biologist perspective. Clin Mol Allergy (2009) 0.83
Differential post-transcriptional regulation of IL-10 by TLR2 and TLR4-activated macrophages. Eur J Immunol (2013) 0.83
Modulation of cancer traits by tumor suppressor microRNAs. Int J Mol Sci (2013) 0.82
Differential microRNA profile and post-transcriptional regulation exist in systemic lupus erythematosus patients with distinct autoantibody specificities. J Clin Immunol (2014) 0.81
Global Egr1-miRNAs binding analysis in PMA-induced K562 cells using ChIP-Seq. J Biomed Biotechnol (2010) 0.81
Novel insights into miRNA in lung and heart inflammatory diseases. Mediators Inflamm (2014) 0.81
Functional regulation of monocyte-derived dendritic cells by microRNAs. Protein Cell (2012) 0.81
Epigenetic response in mice mastitis: Role of histone H3 acetylation and microRNA(s) in the regulation of host inflammatory gene expression during Staphylococcus aureus infection. Clin Epigenetics (2014) 0.79
MicroRNAs in the Host-Apicomplexan Parasites Interactions: A Review of Immunopathological Aspects. Front Cell Infect Microbiol (2016) 0.79
Post-transcriptional Regulation of NK Cell Activation. Immune Netw (2009) 0.78
Comparison of Total RNA Isolation Methods for Analysis of Immune-Related microRNAs in Market Milks. Korean J Food Sci Anim Resour (2015) 0.77
Cellular microRNAs and picornaviral infections. RNA Biol (2014) 0.76
Identification of TLR2 and TLR4‑induced microRNAs in human mesenchymal stem cells and their possible roles in regulating TLR signals. Mol Med Rep (2016) 0.76
The independent contribution of miRNAs to the missing heritability in CYP3A4/5 functionality and the metabolism of atorvastatin. Sci Rep (2016) 0.75
Host Genetic Background Strongly Affects Pulmonary microRNA Expression before and during Influenza A Virus Infection. Front Immunol (2017) 0.75
Differential expression profiling of spleen microRNAs in response to two distinct type II interferons in Tetraodon nigroviridis. PLoS One (2014) 0.75
IL10 in Lupus Nephritis: Detection and relationship with disease activity. Electron Physician (2015) 0.75
X-Linked miRNAs Associated with Gender Differences in Rheumatoid Arthritis. Int J Mol Sci (2016) 0.75
Flow cytometric detection of p38 MAPK phosphorylation and intracellular cytokine expression in peripheral blood subpopulations from patients with autoimmune rheumatic diseases. J Immunol Res (2014) 0.75
Atorvastatin inhibits the immediate-early response gene EGR1 and improves the functional profile of CD4+T-lymphocytes in acute coronary syndromes. Oncotarget (2017) 0.75
Peripheral Signatures of Psychiatric Disorders: MicroRNAs. Clin Psychopharmacol Neurosci (2017) 0.75
Emerging Roles of microRNAs in Ischemic Stroke: As Possible Therapeutic Agents. J Stroke (2017) 0.75
Short-term treatment with eicosapentaenoic acid improves inflammation and affects colonic differentiation markers and microbiota in patients with ulcerative colitis. Sci Rep (2017) 0.75
HTLV-1 Tax upregulates early growth response protein 1 through nuclear factor-κB signaling. Oncotarget (2017) 0.75
MicroRNAs in the miR-17 and miR-15 families are downregulated in chronic kidney disease with hypertension. PLoS One (2017) 0.75
MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 198.59
Prediction of mammalian microRNA targets. Cell (2003) 53.70
Human MicroRNA targets. PLoS Biol (2004) 34.51
MicroRNAs modulate hematopoietic lineage differentiation. Science (2003) 30.05
Fast and effective prediction of microRNA/target duplexes. RNA (2004) 18.10
MicroRNA functions in animal development and human disease. Development (2005) 8.41
A role for Dicer in immune regulation. J Exp Med (2006) 5.81
MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1. Proc Natl Acad Sci U S A (2008) 5.15
AliBaba2: context specific identification of transcription factor binding sites. In Silico Biol (2002) 3.77
T(H)1 cells control themselves by producing interleukin-10. Nat Rev Immunol (2007) 3.65
Interleukin-10 therapy--review of a new approach. Pharmacol Rev (2003) 3.51
Regulation of life and death by the zinc finger transcription factor Egr-1. J Cell Physiol (2002) 3.04
MicroRNAs and immunity: tiny players in a big field. Immunity (2007) 3.01
Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5. Blood (2007) 2.83
Strategies for use of IL-10 or its antagonists in human disease. Immunol Rev (2008) 2.52
Oncogenic potential of the miR-106-363 cluster and its implication in human T-cell leukemia. Cancer Res (2007) 2.52
The p38 mitogen-activated kinase pathway regulates the human interleukin-10 promoter via the activation of Sp1 transcription factor in lipopolysaccharide-stimulated human macrophages. J Biol Chem (2001) 2.23
IL-10 gene expression is controlled by the transcription factors Sp1 and Sp3. J Immunol (2000) 2.04
Targets for human encoded microRNAs in HIV genes. Biochem Biophys Res Commun (2005) 1.99
Interplay of Sp1 and Egr-1 in the proximal platelet-derived growth factor A-chain promoter in cultured vascular endothelial cells. J Biol Chem (1995) 1.79
Posttranscriptional regulation of II10 gene expression allows natural killer cells to express immunoregulatory function. Immunity (2008) 1.65
IL10 gene polymorphisms are associated with asthma phenotypes in children. Genet Epidemiol (2004) 1.64
Posttranscriptional regulation of IL-10 gene expression through sequences in the 3'-untranslated region. J Immunol (2000) 1.60
The immediate-early gene product Egr-1 regulates the human interleukin-2 receptor beta-chain promoter through noncanonical Egr and Sp1 binding sites. Mol Cell Biol (1997) 1.22
Involvement of Egr-1/RelA synergy in distinguishing T cell activation from tumor necrosis factor-alpha-induced NF-kappa B1 transcription. J Exp Med (1997) 1.08
Increased interleukin-10 mRNA stability in melanoma cells is associated with decreased levels of A + U-rich element binding factor AUF1. J Interferon Cytokine Res (2003) 1.05
Transcription of the IL10 gene reveals allele-specific regulation at the mRNA level. Hum Mol Genet (2004) 1.00
Isoliquiritigenin inhibits IkappaB kinase activity and ROS generation to block TNF-alpha induced expression of cell adhesion molecules on human endothelial cells. Biochem Pharmacol (2007) 0.99
Reciprocal regulation of beta(1)-adrenergic receptor gene transcription by Sp1 and early growth response gene 1: induction of EGR-1 inhibits the expression of the beta(1)-adrenergic receptor gene. Mol Pharmacol (2002) 0.93
Direct evidence that ERK regulates the production/secretion of interleukin-2 in PHA/PMA-stimulated T lymphocytes. Immunology (1999) 0.92
Beta-agonists modulate T-cell functions via direct actions on type 1 and type 2 cells. Blood (2005) 0.91
Interleukin-10 suppresses tissue factor expression in lipopolysaccharide-stimulated macrophages via inhibition of Egr-1 and a serum response element/MEK-ERK1/2 pathway. Circ Res (2005) 0.84
Involvement of tyrosine kinases and MAP kinases in the production of TNF-alpha and IL-1beta by macrophages in vitro on treatment with phytohemagglutinin. J Interferon Cytokine Res (2007) 0.79
Personal omics profiling reveals dynamic molecular and medical phenotypes. Cell (2012) 12.32
Annotation of functional variation in personal genomes using RegulomeDB. Genome Res (2012) 11.47
Variation in transcription factor binding among humans. Science (2010) 9.33
Mapping human genetic diversity in Asia. Science (2009) 7.40
Human Proteinpedia enables sharing of human protein data. Nat Biotechnol (2008) 4.21
An encyclopedia of mouse DNA elements (Mouse ENCODE). Genome Biol (2012) 4.15
Whole genome expression and biochemical correlates of extreme constitutional types defined in Ayurveda. J Transl Med (2008) 2.55
Whole body cooling in newborn infants with perinatal asphyxial encephalopathy in a low resource setting: a feasibility trial. Indian Pediatr (2010) 2.13
Targets for human encoded microRNAs in HIV genes. Biochem Biophys Res Commun (2005) 1.99
HGVbaseG2P: a central genetic association database. Nucleic Acids Res (2008) 1.90
Host-virus interaction: a new role for microRNAs. Retrovirology (2006) 1.88
Human cellular microRNA hsa-miR-29a interferes with viral nef protein expression and HIV-1 replication. Retrovirology (2008) 1.87
Alu repeat analysis in the complete human genome: trends and variations with respect to genomic composition. Bioinformatics (2004) 1.77
High-throughput sequencing for biology and medicine. Mol Syst Biol (2013) 1.75
EGLN1 involvement in high-altitude adaptation revealed through genetic analysis of extreme constitution types defined in Ayurveda. Proc Natl Acad Sci U S A (2010) 1.74
Relationship of abdominal bloating to distention in irritable bowel syndrome and effect of bowel habit. Gastroenterology (2006) 1.69
ppGpp: stringent response and survival. J Microbiol (2006) 1.66
Let-7 microRNA-mediated regulation of IL-13 and allergic airway inflammation. J Allergy Clin Immunol (2011) 1.58
Upregulation of miR-23a-27a-24-2 cluster induces caspase-dependent and -independent apoptosis in human embryonic kidney cells. PLoS One (2009) 1.54
Leishmaniasis: current status of available drugs and new potential drug targets. Asian Pac J Trop Med (2012) 1.54
PTEN has tumor-promoting properties in the setting of gain-of-function p53 mutations. Cancer Res (2008) 1.52
Fractional exhaled nitric oxide in children with acute exacerbation of asthma. Indian Pediatr (2013) 1.49
Mechanism of amphotericin B resistance in clinical isolates of Leishmania donovani. Antimicrob Agents Chemother (2011) 1.45
Mammalian gut immunity. Biomed J (2014) 1.43
FoxP3+ regulatory T cells suppress effector T-cell function at pathologic site in miliary tuberculosis. Am J Respir Crit Care Med (2009) 1.43
BosR (BB0647) governs virulence expression in Borrelia burgdorferi. Mol Microbiol (2009) 1.42
Nonrandom distribution of alu elements in genes of various functional categories: insight from analysis of human chromosomes 21 and 22. Mol Biol Evol (2003) 1.42
Miro1 regulates intercellular mitochondrial transport & enhances mesenchymal stem cell rescue efficacy. EMBO J (2014) 1.37
Tracing the factors responsible for arsenic enrichment in groundwater of the middle Gangetic Plain, India: a source identification perspective. Environ Geochem Health (2009) 1.37
Simultaneous, accurate measurement of the 3D position and orientation of single molecules. Proc Natl Acad Sci U S A (2012) 1.36
Inhibition of translation in living eukaryotic cells by an RNA G-quadruplex motif. RNA (2008) 1.34
Mitochondrial structural changes and dysfunction are associated with experimental allergic asthma. J Immunol (2008) 1.32
Host-virus genome interactions: macro roles for microRNAs. Cell Microbiol (2007) 1.28
Consensus miRNA expression profiles derived from interplatform normalization of microarray data. RNA (2009) 1.27
Nitric oxide S-nitrosylates serine racemase, mediating feedback inhibition of D-serine formation. Proc Natl Acad Sci U S A (2007) 1.27
Quadfinder: server for identification and analysis of quadruplex-forming motifs in nucleotide sequences. Nucleic Acids Res (2006) 1.26
Genetic association of acidic mammalian chitinase with atopic asthma and serum total IgE levels. J Allergy Clin Immunol (2008) 1.20
State and socio-demographic group variation in out-of-pocket expenditure, borrowings and Janani Suraksha Yojana (JSY) programme use for birth deliveries in India. BMC Public Health (2012) 1.20
The high prevalence of herpes simplex virus type 1 DNA in human trigeminal ganglia is not a function of age or gender. J Virol (2008) 1.19
Synapse microarray identification of small molecules that enhance synaptogenesis. Nat Commun (2011) 1.19
BB0323 function is essential for Borrelia burgdorferi virulence and persistence through tick-rodent transmission cycle. J Infect Dis (2009) 1.18
Crebinostat: a novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity. Neuropharmacology (2012) 1.18
Assessing natural variations in gene expression in humans by comparing with monozygotic twins using microarrays. Physiol Genomics (2005) 1.16
Evolution and distribution of RNA polymerase II regulatory sites from RNA polymerase III dependant mobile Alu elements. BMC Evol Biol (2004) 1.15
MicroRNA-326 regulates profibrotic functions of transforming growth factor-β in pulmonary fibrosis. Am J Respir Cell Mol Biol (2014) 1.14
Tcf7 is an important regulator of the switch of self-renewal and differentiation in a multipotential hematopoietic cell line. PLoS Genet (2012) 1.14
Boolean network analysis of a neurotransmitter signaling pathway. J Theor Biol (2006) 1.13
Comparative analysis of chromatin landscape in regulatory regions of human housekeeping and tissue specific genes. BMC Bioinformatics (2005) 1.13
Borrelia burgdorferi small lipoprotein Lp6.6 is a member of multiple protein complexes in the outer membrane and facilitates pathogen transmission from ticks to mice. Mol Microbiol (2009) 1.12
Glycyrrhizin alleviates experimental allergic asthma in mice. Int Immunopharmacol (2006) 1.12
Effect of Inhibiting Histone Deacetylase with Short-Chain Carboxylic Acids and Their Hydroxamic Acid Analogs on Vertebrate Development and Neuronal Chromatin. ACS Med Chem Lett (2010) 1.11
Open source drug discovery--a new paradigm of collaborative research in tuberculosis drug development. Tuberculosis (Edinb) (2011) 1.11
A differential role for BB0365 in the persistence of Borrelia burgdorferi in mice and ticks. J Infect Dis (2008) 1.11
Association of TNF haplotypes with asthma, serum IgE levels, and correlation with serum TNF-alpha levels. Am J Respir Cell Mol Biol (2006) 1.11
Pharmacogenomics: a path to predictive medicine for schizophrenia. Pharmacogenomics (2006) 1.10
Nef: "necessary and enforcing factor" in HIV infection. Curr HIV Res (2005) 1.10
Crowd sourcing a new paradigm for interactome driven drug target identification in Mycobacterium tuberculosis. PLoS One (2012) 1.10
Beneficial effects of high dose of L-arginine on airway hyperresponsiveness and airway inflammation in a murine model of asthma. J Allergy Clin Immunol (2010) 1.08
Curcumin attenuates allergen-induced airway hyperresponsiveness in sensitized guinea pigs. Biol Pharm Bull (2003) 1.07
Simvastatin improves epithelial dysfunction and airway hyperresponsiveness: from asymmetric dimethyl-arginine to asthma. Am J Respir Cell Mol Biol (2010) 1.07
dbSMR: a novel resource of genome-wide SNPs affecting microRNA mediated regulation. BMC Bioinformatics (2009) 1.07
Proinflammatory role of epithelial cell-derived exosomes in allergic airway inflammation. J Allergy Clin Immunol (2013) 1.05
Whole genome expression profiles of yeast RNA polymerase II core subunit, Rpb4, in stress and nonstress conditions. J Biol Chem (2002) 1.05
Borrelia burgdorferi complement regulator-acquiring surface protein 2 does not contribute to complement resistance or host infectivity. PLoS One (2008) 1.05
Assessment of the impact of landfill on groundwater quality: a case study of the Pirana site in western India. Environ Monit Assess (2007) 1.05
Altered asymmetric dimethyl arginine metabolism in allergically inflamed mouse lungs. Am J Respir Cell Mol Biol (2009) 1.04
Polarized helper T cells in tubercular pleural effusion: phenotypic identity and selective recruitment. Eur J Immunol (2005) 1.03
Systematic survey of discrepancy rates in an international teleradiology service. Emerg Radiol (2010) 1.03
Linoleic acid metabolite drives severe asthma by causing airway epithelial injury. Sci Rep (2013) 1.02
CO2 permeability of cell membranes is regulated by membrane cholesterol and protein gas channels. FASEB J (2012) 1.02
Prediction of polyadenylation signals in human DNA sequences using nucleotide frequencies. In Silico Biol (2009) 1.00
Nuclear and cytoplasmic accumulation of Ep-ICD is frequently detected in human epithelial cancers. PLoS One (2010) 1.00
India needs a national COPD prevention and control programme. J Assoc Physicians India (2012) 1.00
Lung cancer biomarkers: State of the art. J Carcinog (2013) 1.00
A full-length bifunctional protein involved in c-di-GMP turnover is required for long-term survival under nutrient starvation in Mycobacterium smegmatis. Microbiology (2012) 0.99
Isoliquiritigenin inhibits IkappaB kinase activity and ROS generation to block TNF-alpha induced expression of cell adhesion molecules on human endothelial cells. Biochem Pharmacol (2007) 0.99
Mepacrine inhibits subepithelial fibrosis by reducing the expression of arginase and TGF-beta1 in an extended subacute mouse model of allergic asthma. Am J Physiol Lung Cell Mol Physiol (2009) 0.99
Modification of RelA by O-linked N-acetylglucosamine links glucose metabolism to NF-κB acetylation and transcription. Proc Natl Acad Sci U S A (2012) 0.98
Hypoxia response in asthma: differential modulation on inflammation and epithelial injury. Am J Respir Cell Mol Biol (2012) 0.98