Published in Biomark Insights on June 06, 2007
Ontological differences in first compared to third trimester human fetal placental chorionic stem cells. PLoS One (2012) 0.91
Germline competency of parthenogenetic embryonic stem cells from immature oocytes of adult mouse ovary. Hum Mol Genet (2011) 0.89
Stage-specific germ-cell marker genes are expressed in all mouse pluripotent cell types and emerge early during induced pluripotency. PLoS One (2011) 0.88
Differentiation of induced pluripotent stem cells into male germ cells in vitro through embryoid body formation and retinoic acid or testosterone induction. Biomed Res Int (2012) 0.83
Meiosis in a bottle: new approaches to overcome Mammalian meiocyte study limitations. Genes (Basel) (2011) 0.75
Establishment in culture of pluripotential cells from mouse embryos. Nature (1981) 30.49
Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet (2000) 21.52
Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell (2003) 20.16
Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell (1998) 19.05
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci U S A (1981) 18.96
TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature (1997) 15.75
Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells. Nature (1988) 13.21
Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev (2003) 12.38
Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides. Nature (1988) 7.61
Bone morphogenetic proteins: multifunctional regulators of vertebrate development. Genes Dev (1996) 7.43
Embryonic stem cell differentiation: emergence of a new era in biology and medicine. Genes Dev (2005) 7.27
Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells. Development (1996) 7.00
Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program. Immunity (2002) 6.27
Buffalo rat liver cells produce a diffusible activity which inhibits the differentiation of murine embryonal carcinoma and embryonic stem cells. Dev Biol (1987) 5.96
Blimp-1 is required for the formation of immunoglobulin secreting plasma cells and pre-plasma memory B cells. Immunity (2003) 5.95
A molecular programme for the specification of germ cell fate in mice. Nature (2002) 5.67
New type of POU domain in germ line-specific protein Oct-4. Nature (1990) 5.65
Blimp1 is a critical determinant of the germ cell lineage in mice. Nature (2005) 5.49
Bmp4 is required for the generation of primordial germ cells in the mouse embryo. Genes Dev (1999) 5.19
A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo. Nature (1990) 4.69
Oct-4: gatekeeper in the beginnings of mammalian development. Stem Cells (2001) 4.63
Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells. Cell (1994) 4.60
Derivation of embryonic germ cells and male gametes from embryonic stem cells. Nature (2003) 4.56
Retinoid signaling determines germ cell fate in mice. Science (2006) 4.17
SAP - a putative DNA-binding motif involved in chromosomal organization. Trends Biochem Sci (2000) 4.10
Derivation of oocytes from mouse embryonic stem cells. Science (2003) 4.03
A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells. Cell (1990) 3.97
Retinoic acid regulates sex-specific timing of meiotic initiation in mice. Proc Natl Acad Sci U S A (2006) 3.94
The mouse homolog of Drosophila Vasa is required for the development of male germ cells. Genes Dev (2000) 3.93
Oct-4 transcription factor is differentially expressed in the mouse embryo during establishment of the first two extraembryonic cell lineages involved in implantation. Dev Biol (1994) 3.88
Genetically selected cardiomyocytes from differentiating embronic stem cells form stable intracardiac grafts. J Clin Invest (1996) 3.87
Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells. Nat Cell Biol (2006) 3.65
Differentiation of pluripotent embryonic stem cells into cardiomyocytes. Circ Res (2002) 3.52
Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4. J Biol Chem (1994) 3.49
Primordial germ cells in the mouse embryo during gastrulation. Development (1990) 3.38
Expression and intracellular localization of mouse Vasa-homologue protein during germ cell development. Mech Dev (2000) 3.14
The mouse Dazla gene encodes a cytoplasmic protein essential for gametogenesis. Nature (1997) 3.13
Developmentally regulated expression of a mouse germ cell nuclear antigen examined from embryonic day 11 to adult in male and female mice. Dev Biol (1994) 3.07
Embryonic stem cells can form germ cells in vitro. Proc Natl Acad Sci U S A (2003) 3.03
Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo. Genes Dev (2002) 2.69
Mouse gastrulation: the formation of a mammalian body plan. Mech Dev (1997) 2.68
IFITM/Mil/fragilis family proteins IFITM1 and IFITM3 play distinct roles in mouse primordial germ cell homing and repulsion. Dev Cell (2005) 2.57
Oct4 is required for primordial germ cell survival. EMBO Rep (2004) 2.56
Proliferation and migration of primordial germ cells during compensatory growth in mouse embryos. J Embryol Exp Morphol (1981) 2.55
Clonal analysis of the origin of primordial germ cells in the mouse. Ciba Found Symp (1994) 2.50
POU domain family values: flexibility, partnerships, and developmental codes. Genes Dev (1997) 2.48
TGF-beta signaling by Smad proteins. Adv Immunol (2000) 2.47
POU5F1 (OCT3/4) identifies cells with pluripotent potential in human germ cell tumors. Cancer Res (2003) 2.45
Molecular mechanism to maintain stem cell renewal of ES cells. Cell Struct Funct (2001) 2.41
Proliferation and differentiation of spermatogonial stem cells. Reproduction (2001) 2.40
Stella is a maternal effect gene required for normal early development in mice. Curr Biol (2003) 2.38
Tissue non-specific alkaline phosphatase is expressed in both embryonic and extraembryonic lineages during mouse embryogenesis but is not required for migration of primordial germ cells. Development (1995) 2.31
In vitro-differentiated embryonic stem cells give rise to male gametes that can generate offspring mice. Dev Cell (2006) 2.30
Differential expression of the Oct-4 transcription factor during mouse germ cell differentiation. Mech Dev (1998) 2.28
Mouse germline restriction of Oct4 expression by germ cell nuclear factor. Dev Cell (2001) 2.27
Transcriptional repression by blimp-1 (PRDI-BF1) involves recruitment of histone deacetylase. Mol Cell Biol (2000) 2.24
The zinc finger transcriptional repressor Blimp1/Prdm1 is dispensable for early axis formation but is required for specification of primordial germ cells in the mouse. Development (2005) 2.23
A nexus between Oct-4 and E1A: implications for gene regulation in embryonic stem cells. Cell (1991) 2.18
The allocation of epiblast cells to ectodermal and germ-line lineages is influenced by the position of the cells in the gastrulating mouse embryo. Dev Biol (1996) 2.13
Point mutation in kit receptor tyrosine kinase reveals essential roles for kit signaling in spermatogenesis and oogenesis without affecting other kit responses. EMBO J (2000) 2.13
PRDI-BF1/Blimp-1 repression is mediated by corepressors of the Groucho family of proteins. Genes Dev (1999) 2.09
The kit-ligand (steel factor) and its receptor c-kit/W: pleiotropic roles in gametogenesis and melanogenesis. Dev Suppl (1993) 2.05
Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation. Development (2001) 2.04
Analysis of pleiotropism at the dominant white-spotting (W) locus of the house mouse: a description of ten new W alleles. Genetics (1981) 2.01
Identification of PGC7, a new gene expressed specifically in preimplantation embryos and germ cells. Mech Dev (2002) 1.94
The kit receptor promotes cell survival via activation of PI 3-kinase and subsequent Akt-mediated phosphorylation of Bad on Ser136. Curr Biol (1998) 1.87
The DAZL family proteins are PABP-binding proteins that regulate translation in germ cells. EMBO J (2005) 1.82
In vitro-generated neural precursors participate in mammalian brain development. Proc Natl Acad Sci U S A (1997) 1.73
The fragilis interferon-inducible gene family of transmembrane proteins is associated with germ cell specification in mice. BMC Dev Biol (2003) 1.70
Localization of vasa, a component of Drosophila polar granules, in maternal-effect mutants that alter embryonic anteroposterior polarity. Development (1990) 1.69
Requirement for mast cell growth factor for primordial germ cell survival in culture. Nature (1991) 1.67
Homeostatic regulation of germinal stem cell proliferation by the GDNF/FSH pathway. Mech Dev (2002) 1.65
Use of developmental marker genes to define temporal and spatial patterns of differentiation during embryoid body formation. J Exp Zool (1999) 1.65
Meiosis and differentiation of mouse germ cells. Symp Soc Exp Biol (1984) 1.64
SAF-B protein couples transcription and pre-mRNA splicing to SAR/MAR elements. Nucleic Acids Res (1998) 1.63
Induction of primordial germ cells from murine epiblasts by synergistic action of BMP4 and BMP8B signaling pathways. Proc Natl Acad Sci U S A (2001) 1.56
Correlation of murine embryonic stem cell gene expression profiles with functional measures of pluripotency. Stem Cells (2005) 1.52
Signaling via hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. Curr Opin Cell Biol (1996) 1.50
Testicular cell conditioned medium supports differentiation of embryonic stem cells into ovarian structures containing oocytes. Stem Cells (2005) 1.46
The dynamic expression pattern of B lymphocyte induced maturation protein-1 (Blimp-1) during mouse embryonic development. Mech Dev (2002) 1.42
In-vitro differentiation of pancreatic beta-cells. Differentiation (2001) 1.42
Effects of the steel gene product on mouse primordial germ cells in culture. Nature (1991) 1.41
Restriction enzyme-generated siRNA (REGS) vectors and libraries. Nat Genet (2004) 1.40
BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo. Genes Dev (2004) 1.40
Nature of the spermatogenic arrest in Dazl -/- mice. Biol Reprod (2001) 1.38
Stage-specific expression of the Kit receptor and its ligand (KL) during male gametogenesis in the mouse: a Kit-KL interaction critical for meiosis. Development (1998) 1.37
Dppa3 / Pgc7 / stella is a maternal factor and is not required for germ cell specification in mice. BMC Dev Biol (2004) 1.35
Smad5 is required for mouse primordial germ cell development. Mech Dev (2001) 1.34
Absence of mDazl produces a final block on germ cell development at meiosis. Reproduction (2003) 1.34
Developmental expression of BMP4/ALK3/SMAD5 signaling pathway in the mouse testis: a potential role of BMP4 in spermatogonia differentiation. J Cell Sci (2003) 1.33
Oct4 RNA interference induces trophectoderm differentiation in mouse embryonic stem cells. Genesis (2003) 1.30
Dissection of the c-Kit signaling pathway in mouse primordial germ cells by retroviral-mediated gene transfer. Proc Natl Acad Sci U S A (2002) 1.26
Steel factor and c-kit protooncogene: genetic lessons in signal transduction. Crit Rev Oncog (1994) 1.20
SMAD1 signaling is critical for initial commitment of germ cell lineage from mouse epiblast. Mech Dev (2002) 1.19
Stage-specific tissue and cell interactions play key roles in mouse germ cell specification. Development (2001) 1.15
Role of suppressors of cytokine signaling (Socs) in leukemia inhibitory factor (LIF) -dependent embryonic stem cell survival. FASEB J (2000) 1.09
Developmentally regulated expression of mil-1 and mil-2, mouse interferon-induced transmembrane protein like genes, during formation and differentiation of primordial germ cells. Mech Dev (2002) 1.07
The expression of c-kit protein during oogenesis and early embryonic development. Biol Reprod (1991) 1.06
Immunohistochemical demonstration of placental alkaline phosphatase in various states of testicular development and in germ cell tumours. Int J Androl (1987) 1.04
Multi-lineage 'stem' cells in the mammalian embryo. J Cell Sci Suppl (1988) 1.04
Gene expression profiling of human oocytes following in vivo or in vitro maturation. Hum Reprod (2008) 1.04
Shedding new light on the molecular architecture of oocytes using a combination of synchrotron Fourier transform-infrared and Raman spectroscopic mapping. Anal Chem (2008) 0.92
Reprogramming of DNA replication timing. Stem Cells (2010) 0.87
Density gradients for the isolation of germ cells from embryoid bodies. Reprod Biomed Online (2008) 0.85
The employment of strontium to activate mouse oocytes: effects on spermatid-injection outcome. Reproduction (2006) 0.80
Comparison of mice born after intracytoplasmic sperm injection with in vitro fertilization and natural mating. Mol Reprod Dev (2007) 0.75