Published in Brain on August 18, 2009
Goal-directed and habitual control in the basal ganglia: implications for Parkinson's disease. Nat Rev Neurosci (2010) 3.05
Missing pieces in the Parkinson's disease puzzle. Nat Med (2010) 2.90
Dopamine transporter imaging is associated with long-term outcomes in Parkinson's disease. Mov Disord (2012) 2.18
Disease duration and the integrity of the nigrostriatal system in Parkinson's disease. Brain (2013) 2.09
Blood oxygenation level-dependent activation in basal ganglia nuclei relates to specific symptoms in de novo Parkinson's disease. Mov Disord (2010) 1.21
A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats. Brain (2013) 1.07
Disease progression in patients with single, large-scale mitochondrial DNA deletions. Brain (2013) 1.02
Parkinson subtypes progress differently in clinical course and imaging pattern. PLoS One (2012) 1.02
Imaging insights into basal ganglia function, Parkinson's disease, and dystonia. Lancet (2014) 1.00
Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration. Neurobiol Dis (2015) 0.99
Neuroimaging in Parkinson's disease. Neurotherapeutics (2011) 0.95
The prediagnostic phase of Parkinson's disease. J Neurol Neurosurg Psychiatry (2016) 0.87
Subregional 6-[18F]fluoro-ʟ-m-tyrosine uptake in the striatum in Parkinson's disease. BMC Neurol (2011) 0.86
The nature of progression in Parkinson's disease: an application of non-linear, multivariate, longitudinal random effects modelling. PLoS One (2013) 0.85
Dopamine overdose hypothesis: evidence and clinical implications. Mov Disord (2013) 0.85
A family with Parkinsonism, essential tremor, restless legs syndrome, and depression. Neurology (2011) 0.84
Safety and tolerability of intracerebroventricular PDGF-BB in Parkinson's disease patients. J Clin Invest (2015) 0.82
Imaging of Dopamine in PD and Implications for Motor and Neuropsychiatric Manifestations of PD. Front Neurol (2013) 0.81
Testing the contributions of striatal dopamine loss to the genesis of parkinsonian signs. Neurobiol Dis (2012) 0.80
Molecular imaging needles: dual-modality optical coherence tomography and fluorescence imaging of labeled antibodies deep in tissue. Biomed Opt Express (2015) 0.80
Dopamine function and the efficiency of human movement. J Cogn Neurosci (2013) 0.79
Exploring the use of shape and texture descriptors of positron emission tomography tracer distribution in imaging studies of neurodegenerative disease. J Cereb Blood Flow Metab (2015) 0.78
Inter-hemispheric asymmetry of nigrostriatal dopaminergic lesion: a possible compensatory mechanism in Parkinson's disease. Front Syst Neurosci (2011) 0.78
Monoamine reuptake inhibitors in Parkinson's disease. Parkinsons Dis (2015) 0.78
Positron emission tomography imaging in neurological disorders. J Neurol (2012) 0.77
A familial form of parkinsonism, dementia, and motor neuron disease: a longitudinal study. Parkinsonism Relat Disord (2014) 0.77
Quantitative connection between polyglutamine aggregation kinetics and neurodegenerative process in patients with Huntington's disease. Mol Neurodegener (2012) 0.76
Ipsilateral deficits of dopaminergic neurotransmission in Parkinson's disease. Ann Clin Transl Neurol (2015) 0.76
A review of disease progression models of Parkinson's disease and applications in clinical trials. Mov Disord (2016) 0.76
Application of texture analysis to DAT SPECT imaging: Relationship to clinical assessments. Neuroimage Clin (2016) 0.76
The influence of dopaminergic striatal innervation on upper limb locomotor synergies. PLoS One (2012) 0.76
Individual time course of pre- and postsynaptic PET imaging may improve differential diagnosis of Parkinson's disease and multiple system atrophy: a case report. BMC Res Notes (2015) 0.75
Striatal and Hippocampal Atrophy in Idiopathic Parkinson's Disease Patients without Dementia: A Morphometric Analysis. Front Neurol (2017) 0.75
Relationship Between Obesity, Alzheimer's Disease, and Parkinson's Disease: an Astrocentric View. Mol Neurobiol (2016) 0.75
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron (2004) 14.35
Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease. N Engl J Med (2009) 7.53
Double-blind study of botulinum toxin in spasmodic torticollis. Lancet (1986) 4.54
Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies. Neurology (1996) 4.42
Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood. J Exp Med (1999) 4.27
Natural history of normal-tension glaucoma. Ophthalmology (2001) 4.00
DCTN1 mutations in Perry syndrome. Nat Genet (2009) 3.87
A meta-analysis of the effect of Bacille Calmette Guérin vaccination on tuberculin skin test measurements. Thorax (2002) 3.65
Studies of the Uptake of Nitrate in Barley: I. Kinetics of NO(3) Influx. Plant Physiol (1990) 3.63
Phenotypic mechanism of HIV-1 resistance to 3'-azido-3'-deoxythymidine (AZT): increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase. Biochemistry (1998) 3.59
Pollen-specific gene expression in transgenic plants: coordinate regulation of two different tomato gene promoters during microsporogenesis. Development (1990) 3.48
Prospective identification and triage of nonemergency patients out of an emergency department: a 5-year study. Ann Emerg Med (1995) 3.27
Expectation and dopamine release: mechanism of the placebo effect in Parkinson's disease. Science (2001) 3.18
Studies of the Regulation of Nitrate Influx by Barley Seedlings Using NO(3). Plant Physiol (1989) 3.05
The role of radiotracer imaging in Parkinson disease. Neurology (2005) 3.02
The effect of age on the nerve fiber population of the human optic nerve. Am J Ophthalmol (1984) 2.94
Risk factors for progression of visual field abnormalities in normal-tension glaucoma. Am J Ophthalmol (2001) 2.84
A large family of genes that share homology with CLAVATA3. Plant Physiol (2001) 2.84
A scoring error in the Mini-Mental State test. Can J Psychiatry (1993) 2.69
Isolation and expression of an anther-specific gene from tomato. Mol Gen Genet (1989) 2.51
PET in LRRK2 mutations: comparison to sporadic Parkinson's disease and evidence for presymptomatic compensation. Brain (2005) 2.40
Bilateral human fetal striatal transplantation in Huntington's disease. Neurology (2002) 2.34
Biochemical variations in the synaptic level of dopamine precede motor fluctuations in Parkinson's disease: PET evidence of increased dopamine turnover. Ann Neurol (2001) 2.31
Risk factors for clustering of tuberculosis cases: a systematic review of population-based molecular epidemiology studies. Int J Tuberc Lung Dis (2008) 2.21
Promoter analysis of genes that are coordinately expressed during pollen development reveals pollen-specific enhancer sequences and shared regulatory elements. Genes Dev (1991) 2.21
The rate of progression of scotomas in glaucoma. Am J Ophthalmol (1986) 2.13
The cost of moderate and severe COPD exacerbations to the Canadian healthcare system. Respir Med (2007) 2.09
Reporting risks and benefits of therapy by use of the concepts of unqualified success and unmitigated failure: applications to highly cited trials in cardiovascular medicine. Circulation (1999) 2.09
Delayed stimulus control: recall for single and relational stimuli. J Exp Anal Behav (1982) 2.05
A clinic-based study of the LRRK2 gene in Parkinson disease yields new mutations. Neurology (2005) 2.00
Manganese neurotoxicity: a review of clinical features, imaging and pathology. Neurotoxicology (1999) 1.97
Neutrophils exposed to bacterial lipopolysaccharide upregulate NADPH oxidase assembly. J Clin Invest (1998) 1.95
Assembly of the neutrophil respiratory burst oxidase. Protein kinase C promotes cytoskeletal and membrane association of cytosolic oxidase components. J Biol Chem (1991) 1.92
Survival analysis for success of Molteno tube implants. Br J Ophthalmol (2001) 1.88
LAT52 protein is essential for tomato pollen development: pollen expressing antisense LAT52 RNA hydrates and germinates abnormally and cannot achieve fertilization. Plant J (1994) 1.87
Genetic heterogeneity in familial idiopathic basal ganglia calcification (Fahr disease). Neurology (2004) 1.87
Autosomal dominant parkinsonism associated with variable synuclein and tau pathology. Neurology (2004) 1.86
sidecar pollen, an Arabidopsis thaliana male gametophytic mutant with aberrant cell divisions during pollen development. Development (1996) 1.85
Diagnostic accuracy of self collected vaginal specimens for human papillomavirus compared to clinician collected human papillomavirus specimens: a meta-analysis. Sex Transm Infect (2005) 1.81
Gametophytic and sporophytic expression of anther-specific genes in developing tomato anthers. Plant Cell (1989) 1.79
Response of blood flow to warm and cold in normal and low-tension glaucoma patients. Am J Ophthalmol (1988) 1.78
The area of the neuroretinal rim of the optic nerve in normal eyes. Am J Ophthalmol (1987) 1.78
Pigment synthesis in maize aleurone from precursors fed to anthocyanin mutants. Biochem Genet (1978) 1.78
Positron emission tomography in manganese intoxication. Ann Neurol (1989) 1.78
Collagen XVIII, containing an endogenous inhibitor of angiogenesis and tumor growth, plays a critical role in the maintenance of retinal structure and in neural tube closure (Knobloch syndrome). Hum Mol Genet (2000) 1.76
Pten (phosphatase and tensin homologue gene) haploinsufficiency promotes insulin hypersensitivity. Diabetologia (2006) 1.72
[11C]DTBZ-PET correlates of levodopa responses in asymmetric Parkinson's disease. Brain (2003) 1.70
The normal human optic nerve. Axon count and axon diameter distribution. Ophthalmology (1989) 1.69
The antiparkinson efficacy of deprenyl derives from transient improvement that is likely to be symptomatic. Ann Neurol (1992) 1.67
Epidemiologic health survey of grain elevator workers in British Columbia. Am Rev Respir Dis (1980) 1.67
Rationale, design and methods of the HEALTHY study nutrition intervention component. Int J Obes (Lond) (2009) 1.65
Levodopa-induced changes in synaptic dopamine levels increase with progression of Parkinson's disease: implications for dyskinesias. Brain (2004) 1.65
In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease. Ann Neurol (2000) 1.65
Neuroretinal rim area in early glaucoma. Am J Ophthalmol (1985) 1.61
PET demonstrates reduced dopamine transporter expression in PD with dyskinesias. Neurology (2008) 1.60
Clinical spectrum of nonmenstrual toxic shock syndrome (TSS): comparison with menstrual TSS by multivariate discriminant analyses. Clin Infect Dis (1993) 1.60
Molecular and genetic characterization of two pollen-expressed genes that have sequence similarity to pectate lyases of the plant pathogen Erwinia. Plant Mol Biol (1990) 1.60
The N gene of tobacco confers resistance to tobacco mosaic virus in transgenic tomato. Proc Natl Acad Sci U S A (1996) 1.59
SLC20A2 and THAP1 deletion in familial basal ganglia calcification with dystonia. Neurogenetics (2013) 1.58
Dendritic degeneration in neostriatal medium spiny neurons in Parkinson disease. Neurology (2005) 1.56
Article 5. Strategic decision making, motivation theory, and junior doctor interviews. Emerg Med J (2001) 1.55
Pollen tube localization implies a role in pollen-pistil interactions for the tomato receptor-like protein kinases LePRK1 and LePRK2. Plant Cell (1998) 1.55
Patients' perceptions of family emotional climate and outcome in schizophrenia. Br J Psychiatry (1993) 1.55
Selective serotonin reuptake inhibitors (SSRIs) for depressive disorders in children and adolescents. Cochrane Database Syst Rev (2007) 1.54
Ac transposition from a T-DNA can generate linked and unlinked clusters of insertions in the tomato genome. Genetics (1991) 1.52
Transient expression of chimeric genes delivered into pollen by microprojectile bombardment. Plant Physiol (1989) 1.50
Pattern of dopaminergic loss in the striatum of humans with MPTP induced parkinsonism. J Neurol Neurosurg Psychiatry (2000) 1.49
Pollen germinates precociously in the anthers of raring-to-go, an Arabidopsis gametophytic mutant. Plant Physiol (2001) 1.49
Studies of the Uptake of Nitrate in Barley : II. Energetics. Plant Physiol (1990) 1.49
GABA-immunoreactive neurons in the dorsal horn of the rat spinal cord. Neuroscience (1989) 1.48
Receiver operating characteristic curve analysis in the prediction of carpal tunnel syndrome: a model for reporting electrophysiological data. Muscle Nerve (1993) 1.48
Adoption of guidelines for Universal Precautions and Body Substance Isolation in Canadian acute-care hospitals. Infect Control Hosp Epidemiol (1990) 1.47
Positron emission tomography suggests that the rate of progression of idiopathic parkinsonism is slow. Ann Neurol (1991) 1.46
Bioethics for clinicians: 18. Aboriginal cultures. CMAJ (2000) 1.46
Face-brain asymmetry in autism spectrum disorders. Mol Psychiatry (2008) 1.45
Which clinical sign of Parkinson's disease best reflects the nigrostriatal lesion? Ann Neurol (1997) 1.45
Geographic trends in incidence of hip fractures: a comprehensive literature review. Osteoporos Int (2011) 1.44
Lymphocytes from the site of disease but not blood lymphocytes indicate the cause of arthritis. Ann Rheum Dis (1985) 1.44