Published in J Med Chem on September 10, 2009
Aminoglycoside binding to Oxytricha nova telomeric DNA. Biochemistry (2010) 0.98
Methods to enable the design of bioactive small molecules targeting RNA. Org Biomol Chem (2014) 0.86
Identification of HIV-1 inhibitors targeting the nucleocapsid protein. J Med Chem (2012) 0.85
Beyond plasma membrane targeting: role of the MA domain of Gag in retroviral genome encapsidation. J Mol Biol (2011) 0.83
Palladium-catalyzed carbonylative cyclization/arylation cascade for 2-aroylindolizine synthesis. Org Lett (2012) 0.79
HIV-1 Gag as an Antiviral Target: Development of Assembly and Maturation Inhibitors. Curr Top Med Chem (2016) 0.78
Advances in targeting nucleocapsid-nucleic acid interactions in HIV-1 therapy. Virus Res (2014) 0.77
A simple ligand that selectively targets CUG trinucleotide repeats and inhibits MBNL protein binding. Proc Natl Acad Sci U S A (2009) 1.63
Molecular dynamics simulation studies of induced fit and conformational capture in U1A-RNA binding: do molecular substates code for specificity? Biopolymers (2002) 1.12
Investigation of a conserved stacking interaction in target site recognition by the U1A protein. Nucleic Acids Res (2002) 1.11
Do collective atomic fluctuations account for cooperative effects? Molecular dynamics studies of the U1A-RNA complex. J Am Chem Soc (2006) 1.03
A study of collective atomic fluctuations and cooperativity in the U1A-RNA complex based on molecular dynamics simulations. J Struct Biol (2006) 1.03
MBNL1-RNA recognition: contributions of MBNL1 sequence and RNA conformation. Chembiochem (2011) 0.96
Targeting toxic RNAs that cause myotonic dystrophy type 1 (DM1) with a bisamidinium inhibitor. J Am Chem Soc (2014) 0.96
Selective inhibition of MBNL1-CCUG interaction by small molecules toward potential therapeutic agents for myotonic dystrophy type 2 (DM2). Nucleic Acids Res (2011) 0.93
A novel CUG(exp)·MBNL1 inhibitor with therapeutic potential for myotonic dystrophy type 1. ACS Chem Biol (2013) 0.93
Affinity and specificity of protein U1A-RNA complex formation based on an additive component free energy model. J Mol Biol (2007) 0.89
Molecular dynamics simulation studies of a protein-RNA complex with a selectively modified binding interface. Biopolymers (2006) 0.87
Molecular recognition of a thymine bulge by a high affinity, deazaguanine-based hydrogen-bonding ligand. Chem Commun (Camb) (2008) 0.85
Design of an adenosine analogue that selectively improves the affinity of a mutant U1A protein for RNA. J Am Chem Soc (2003) 0.85
Substitution of an essential adenine in the U1A-RNA complex with a non-polar isostere. Nucleic Acids Res (2002) 0.85
Multistep kinetics of the U1A-SL2 RNA complex dissociation. J Mol Biol (2011) 0.84
Characterization of the dynamics of an essential helix in the U1A protein by time-resolved fluorescence measurements. J Phys Chem B (2008) 0.84
Binding of an aminoacridine derivative to a GAAA RNA tetraloop. Bioorg Med Chem Lett (2004) 0.83
Identification of small molecule inhibitors of the HIV-1 nucleocapsid-stem-loop 3 RNA complex. J Med Chem (2012) 0.81
Identification of an aminoacridine derivative that binds to RNA tetraloops. J Med Chem (2007) 0.81
Recognition of essential purines by the U1A protein. BMC Biochem (2007) 0.80
Investigating the binding mode of an inhibitor of the MBNL1·RNA complex in myotonic dystrophy type 1 (DM1) leads to the unexpected discovery of a DNA-selective binder. Chembiochem (2012) 0.80
Cooperative binding of a quinoline derivative to an RNA stem loop containing a dangling end. Bioorg Med Chem Lett (2010) 0.79
Characterization of two adenosine analogs as fluorescence probes in RNA. Bioorg Chem (2008) 0.79
Control of the stability of a protein-RNA complex by the position of fluorine in a base analogue. J Am Chem Soc (2011) 0.78
Selective recognition of RNA helices containing dangling ends by a quinoline derivative. Chembiochem (2007) 0.76
Inhibition of the U1A-RNA complex by an aminoacridine derivative. Bioorg Med Chem Lett (2002) 0.76
U1A protein-stem loop 2 RNA recognition: prediction of structural differences from protein mutations. Biopolymers (2011) 0.76