Functional analyses of cytochrome P450 genes responsible for the early steps of brassicicene C biosynthesis.

PubWeight™: 0.82‹?›

🔗 View Article (PMID 19700326)

Published in Bioorg Med Chem Lett on August 08, 2009

Authors

Makoto Hashimoto1, Yusuke Higuchi, Shunji Takahashi, Hiroyuki Osada, Toshiyuki Sakaki, Tomonobu Toyomasu, Takeshi Sassa, Nobuo Kato, Tohru Dairi

Author Affiliations

1: Biotechnology Research Center, Toyama Prefectural University, Imizu, Toyama 939-0398, Japan. mhashimo@iwate-med.ac.jp

Articles by these authors

In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation. EMBO J (2002) 4.28

M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP. Proc Natl Acad Sci U S A (2004) 4.13

Semi-wet peptide/protein array using supramolecular hydrogel. Nat Mater (2003) 2.47

An alternative menaquinone biosynthetic pathway operating in microorganisms. Science (2008) 2.46

Inhibition of ADP/ATP exchange in receptor-interacting protein-mediated necrosis. Mol Cell Biol (2006) 2.03

A rice semi-dwarf gene, Tan-Ginbozu (D35), encodes the gibberellin biosynthesis enzyme, ent-kaurene oxidase. Plant Mol Biol (2004) 2.00

Identification of a biosynthetic gene cluster in rice for momilactones. J Biol Chem (2007) 1.96

Cyclin-dependent kinase (CDK) phosphorylation destabilizes somatic Wee1 via multiple pathways. Proc Natl Acad Sci U S A (2005) 1.85

Clinicopathological characteristics of breast cancer and trends in the management of breast cancer patients in Japan: Based on the Breast Cancer Registry of the Japanese Breast Cancer Society between 2004 and 2011. Breast Cancer (2015) 1.64

Biological functions of ent- and syn-copalyl diphosphate synthases in rice: key enzymes for the branch point of gibberellin and phytoalexin biosynthesis. Plant J (2004) 1.64

Reveromycin A biosynthesis uses RevG and RevJ for stereospecific spiroacetal formation. Nat Chem Biol (2011) 1.62

Tissue-specific localization of an abscisic acid biosynthetic enzyme, AAO3, in Arabidopsis. Plant Physiol (2004) 1.60

The anticancer natural product pironetin selectively targets Lys352 of alpha-tubulin. Chem Biol (2004) 1.59

Reduction of indoxyl sulfate by AST-120 attenuates monocyte inflammation related to chronic kidney disease. J Leukoc Biol (2013) 1.57

Mycobacterium tuberculosis H37Rv3377c encodes the diterpene cyclase for producing the halimane skeleton. Chem Commun (Camb) (2005) 1.56

Drought induction of Arabidopsis 9-cis-epoxycarotenoid dioxygenase occurs in vascular parenchyma cells. Plant Physiol (2008) 1.52

Paz2 and 13 other PAZ gene products regulate vacuolar engulfment of peroxisomes during micropexophagy. Genes Cells (2002) 1.51

Functional analysis of eubacterial diterpene cyclases responsible for biosynthesis of a diterpene antibiotic, terpentecin. J Biol Chem (2002) 1.48

Suppression of apoptosis by cyclophilin D via stabilization of hexokinase II mitochondrial binding in cancer cells. J Biol Chem (2006) 1.48

Relationship between bone mineral density and androgen-deprivation therapy in Japanese prostate cancer patients. Urology (2010) 1.46

Bisphosphonate-related osteonecrosis of the jaw: position paper from the Allied Task Force Committee of Japanese Society for Bone and Mineral Research, Japan Osteoporosis Society, Japanese Society of Periodontology, Japanese Society for Oral and Maxillofacial Radiology, and Japanese Society of Oral and Maxillofacial Surgeons. J Bone Miner Metab (2010) 1.44

Molecular cloning and characterization of a cDNA encoding ent-cassa-12,15-diene synthase, a putative diterpenoid phytoalexin biosynthetic enzyme, from suspension-cultured rice cells treated with a chitin elicitor. Plant J (2004) 1.42

Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands. Proc Natl Acad Sci U S A (2009) 1.40

Quantitative analysis of UDP-glucuronosyltransferase (UGT) 1A and UGT2B expression levels in human livers. Drug Metab Dispos (2009) 1.34

Propane monooxygenase and NAD+-dependent secondary alcohol dehydrogenase in propane metabolism by Gordonia sp. strain TY-5. J Bacteriol (2003) 1.34

Intestinal and hepatic CYP3A4 catalyze hydroxylation of 1alpha,25-dihydroxyvitamin D(3): implications for drug-induced osteomalacia. Mol Pharmacol (2005) 1.33

The nosocomial transmission of Helicobacter cinaedi infections in immunocompromised patients. Intern Med (2010) 1.32

The ribulose monophosphate pathway substitutes for the missing pentose phosphate pathway in the archaeon Thermococcus kodakaraensis. J Bacteriol (2006) 1.31

Inhibition of Hsp90 activates osteoclast c-Src signaling and promotes growth of prostate carcinoma cells in bone. Proc Natl Acad Sci U S A (2008) 1.28

C-3 epimerization of vitamin D3 metabolites and further metabolism of C-3 epimers: 25-hydroxyvitamin D3 is metabolized to 3-epi-25-hydroxyvitamin D3 and subsequently metabolized through C-1alpha or C-24 hydroxylation. J Biol Chem (2004) 1.28

Characterization of a rice gene family encoding type-A diterpene cyclases. Biosci Biotechnol Biochem (2006) 1.26

A sorting nexin PpAtg24 regulates vacuolar membrane dynamics during pexophagy via binding to phosphatidylinositol-3-phosphate. Mol Biol Cell (2004) 1.26

Peroxisome degradation requires catalytically active sterol glucosyltransferase with a GRAM domain. EMBO J (2003) 1.26

Flare-up of dermatomyositis along with recurrence of breast cancer. Breast J (2007) 1.25

Enzymatic generation of the antimetabolite gamma,gamma-dichloroaminobutyrate by NRPS and mononuclear iron halogenase action in a streptomycete. Chem Biol (2006) 1.25

Biosynthesis of a natural polyketide-isoprenoid hybrid compound, furaquinocin A: identification and heterologous expression of the gene cluster. J Bacteriol (2006) 1.22

A cold-regulated nucleic acid-binding protein of winter wheat shares a domain with bacterial cold shock proteins. J Biol Chem (2002) 1.22

Molecular cloning and characterization of CYP719, a methylenedioxy bridge-forming enzyme that belongs to a novel P450 family, from cultured Coptis japonica cells. J Biol Chem (2003) 1.21

The phosphorylation status and anti-apoptotic activity of Bcl-2 are regulated by ERK and protein phosphatase 2A on the mitochondria. FEBS Lett (2004) 1.20

Deficiency in chromosome congression by the inhibition of Plk1 polo box domain-dependent recognition. J Biol Chem (2008) 1.20

Modification of a ubiquitin-like protein Paz2 conducted micropexophagy through formation of a novel membrane structure. Mol Biol Cell (2003) 1.20

Inhibition of bone and muscle metastases of lung cancer cells by a decrease in the number of monocytes/macrophages. Cancer Sci (2008) 1.18

Identification of a strong binding site for kinesin on the microtubule using mutant analysis of tubulin. EMBO J (2006) 1.18

Cellulose complementing factor (Ccp) is a new member of the cellulose synthase complex (terminal complex) in Acetobacter xylinum. J Biosci Bioeng (2013) 1.15

A comparative analysis of the sugar phosphate cyclase superfamily involved in primary and secondary metabolism. Chembiochem (2007) 1.15

Diterpene cyclases responsible for the biosynthesis of phytoalexins, momilactones A, B, and oryzalexins A-F in rice. Biosci Biotechnol Biochem (2004) 1.14

Suppression of synaptic plasticity by cerebrospinal fluid from anti-NMDA receptor encephalitis patients. Neurobiol Dis (2011) 1.13

Wax ester production by bacteria. Curr Opin Microbiol (2003) 1.13

Synthesis of (+)-vinblastine and its analogues. Org Lett (2007) 1.12

Fusicoccins are biosynthesized by an unusual chimera diterpene synthase in fungi. Proc Natl Acad Sci U S A (2007) 1.12

Studies on a new biosynthetic pathway for menaquinone. J Am Chem Soc (2008) 1.12

The identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase I. Proc Natl Acad Sci U S A (2008) 1.10

Chemical genetic screening identifies a novel inhibitor of parallel alignment of cortical microtubules and cellulose microfibrils. Plant Cell Physiol (2007) 1.10

Enhancement and selective production of phoslactomycin B, a protein phosphatase IIa inhibitor, through identification and engineering of the corresponding biosynthetic gene cluster. J Biol Chem (2003) 1.10

Azaspirene: a novel angiogenesis inhibitor containing a 1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione skeleton produced by the fungus Neosartorya sp. Org Lett (2002) 1.10

Assimilation, dissimilation, and detoxification of formaldehyde, a central metabolic intermediate of methylotrophic metabolism. Chem Rec (2005) 1.10

Crystal structure of CYP105A1 (P450SU-1) in complex with 1alpha,25-dihydroxyvitamin D3. Biochemistry (2008) 1.08

RECK negatively regulates matrix metalloproteinase-9 transcription. Cancer Res (2009) 1.08

Reversal of breast cancer resistance protein-mediated drug resistance by tryprostatin A. Int J Cancer (2003) 1.07

Aerobic and anaerobic toluene degradation by a newly isolated denitrifying bacterium, Thauera sp. strain DNT-1. Appl Environ Microbiol (2004) 1.06

SPR imaging of photo-cross-linked small-molecule arrays on gold. Anal Chem (2006) 1.06

Metabolism of vitamin D by human microsomal CYP2R1. Biochem Biophys Res Commun (2004) 1.06

Functional analysis of eubacterial ent-copalyl diphosphate synthase and pimara-9(11),15-diene synthase with unique primary sequences. J Biochem (2006) 1.05

Morphobase, an encyclopedic cell morphology database, and its use for drug target identification. Chem Biol (2012) 1.05

Disruption of a single copy of the p38alpha MAP kinase gene leads to cardioprotection against ischemia-reperfusion. Biochem Biophys Res Commun (2003) 1.05

Chiral alcohol production by NADH-dependent phenylacetaldehyde reductase coupled with in situ regeneration of NADH. Eur J Biochem (2002) 1.04

Stemar-13-ene synthase, a diterpene cyclase involved in the biosynthesis of the phytoalexin oryzalexin S in rice. FEBS Lett (2004) 1.04

Novel acetone metabolism in a propane-utilizing bacterium, Gordonia sp. strain TY-5. J Bacteriol (2006) 1.04

Eremophilane sesquiterpenes from capsidiol. J Org Chem (2004) 1.04

1,25-(OH)2D-24 Hydroxylase (CYP24A1) Deficiency as a Cause of Nephrolithiasis. Clin J Am Soc Nephrol (2013) 1.04

The aryl hydrocarbon receptor activator benzo[a]pyrene enhances vitamin D3 catabolism in macrophages. Toxicol Sci (2009) 1.03

Identification of cytochrome P450s required for fumitremorgin biosynthesis in Aspergillus fumigatus. Chembiochem (2009) 1.03

Indoxyl sulfate induces leukocyte-endothelial interactions through up-regulation of E-selectin. J Biol Chem (2010) 1.03

Characterization of the tautomycetin biosynthetic gene cluster from Streptomyces griseochromogenes provides new insight into dialkylmaleic anhydride biosynthesis. J Nat Prod (2009) 1.03

Heparanase as a molecular target of cancer chemotherapy. Cancer Sci (2004) 1.02

HxlR, a member of the DUF24 protein family, is a DNA-binding protein that acts as a positive regulator of the formaldehyde-inducible hxlAB operon in Bacillus subtilis. Mol Microbiol (2005) 1.02

Biochemical characterization of a novel indole prenyltransferase from Streptomyces sp. SN-593. J Bacteriol (2010) 1.02

Emergence of endoplasmic reticulum stress and activated microglia in Purkinje cell degeneration mice. Neurosci Lett (2005) 1.02

Phytochrome- and gibberellin-mediated regulation of abscisic acid metabolism during germination of photoblastic lettuce seeds. Plant Physiol (2008) 1.01

The roles of cytochrome P450 enzymes in prostate cancer development and treatment. Anticancer Res (2012) 1.01

Effects of combined treatment with rapamycin and cotylenin A, a novel differentiation-inducing agent, on human breast carcinoma MCF-7 cells and xenografts. Breast Cancer Res (2005) 1.00

Clinical efficacy and prognostic factors for overall survival in Japanese patients with metastatic renal cell cancer treated with sunitinib. BJU Int (2011) 1.00

Prognostic impact of pretreatment C-reactive protein for patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitors. Int J Clin Oncol (2012) 1.00

Identification of CD20 C-terminal deletion mutations associated with loss of CD20 expression in non-Hodgkin's lymphoma. Clin Cancer Res (2009) 1.00

A novel lactonohydrolase responsible for the detoxification of zearalenone: enzyme purification and gene cloning. Biochem J (2002) 1.00

High prevalence of HER-2/neu and p53 overexpression in inflammatory breast cancer. Breast Cancer (2006) 0.99

Treatment outcome and prognostic factors in renal cell cancer patients with bone metastasis. Clin Exp Metastasis (2011) 0.99

A small-molecule inhibitor shows that pirin regulates migration of melanoma cells. Nat Chem Biol (2010) 0.98

Helicobacter cinaedi and Helicobacter fennelliae transmission in a hospital from 2008 to 2012. J Clin Microbiol (2013) 0.98