Marc Therrien

Author PubWeight™ 25.96‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A dimerization-dependent mechanism drives RAF catalytic activation. Nature 2009 5.39
2 KSR is a scaffold required for activation of the ERK/MAPK module. Genes Dev 2002 2.40
3 The John Charnley Award: The functional outcome of hip resurfacing and large-head THA is the same: a randomized, double-blind study. Clin Orthop Relat Res 2009 2.23
4 A comprehensive map of the mTOR signaling network. Mol Syst Biol 2010 1.59
5 The exon junction complex controls the splicing of MAPK and other long intron-containing transcripts in Drosophila. Cell 2010 1.44
6 A KSR/CNK complex mediated by HYP, a novel SAM domain-containing protein, regulates RAS-dependent RAF activation in Drosophila. Genes Dev 2006 1.35
7 Inhibitors that stabilize a closed RAF kinase domain conformation induce dimerization. Nat Chem Biol 2013 1.10
8 Mechanistic principles of RAF kinase signaling. Cell Mol Life Sci 2010 1.07
9 CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling. Proc Natl Acad Sci U S A 2008 0.99
10 Bimodal regulation of RAF by CNK in Drosophila. EMBO J 2003 0.97
11 MAP kinase module: the Ksr connection. Curr Biol 2002 0.87
12 Cancer: A drug-resistant duo. Nature 2011 0.84
13 Src42 binding activity regulates Drosophila RAF by a novel CNK-dependent derepression mechanism. EMBO J 2005 0.83
14 Assessment of seated postural control in children: comparison of a force platform versus a pressure mapping system. Arch Phys Med Rehabil 2006 0.81
15 Stability of children with cerebral palsy in their wheelchair seating: perceptions of parents and therapists. Disabil Rehabil Assist Technol 2009 0.80
16 The PP2C Alphabet is a negative regulator of stress-activated protein kinase signaling in Drosophila. Genetics 2008 0.80
17 [The greater RTK/RAS/ERK signalling pathway: how genetics has helped piece together a signalling network]. Med Sci (Paris) 2010 0.78
18 The exon junction complex: a splicing factor for long intron containing transcripts? Fly (Austin) 2011 0.78
19 Alphabet, a Ser/Thr phosphatase of the protein phosphatase 2C family, negatively regulates RAS/MAPK signaling in Drosophila. Dev Biol 2006 0.77
20 Center of Mass Compensation during Gait in Hip Arthroplasty Patients: Comparison between Large Diameter Head Total Hip Arthroplasty and Hip Resurfacing. Rehabil Res Pract 2011 0.77
21 [It takes two RAFs to tango]. Med Sci (Paris) 2010 0.75