Published in Immunology on October 01, 2009
Interrogating the repertoire: broadening the scope of peptide-MHC multimer analysis. Nat Rev Immunol (2011) 1.32
Toxin-coupled MHC class I tetramers can specifically ablate autoreactive CD8+ T cells and delay diabetes in nonobese diabetic mice. J Immunol (2010) 1.07
The use of peptide-major-histocompatibility-complex multimers in type 1 diabetes mellitus. J Diabetes Sci Technol (2012) 0.77
Making the most of major histocompatibility complex molecule multimers: applications in type 1 diabetes. Clin Dev Immunol (2012) 0.76
Deletion of naïve T cells recognizing the minor histocompatibility antigen HY with toxin-coupled peptide-MHC class I tetramers inhibits cognate CTL responses and alters immunodominance. Transpl Immunol (2013) 0.76
CD8 T-cell regulation by T regulatory cells and the programmed cell death protein 1 pathway. Immunology (2017) 0.75
Identifiable biomarker and treatment development using HIV-1 long term non-progressor sera. BMC Immunol (2015) 0.75
HLA-B*14:02-RESTRICTED ENV-SPECIFIC CD8+ T-CELL ACTIVITY HAS HIGHLY POTENT ANTIVIRAL EFFICACY ASSOCIATED WITH IMMUNE CONTROL OF HIV INFECTION. J Virol (2017) 0.75
Phenotypic analysis of antigen-specific T lymphocytes. Science (1996) 24.26
Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection. Immunity (1998) 17.27
Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice. Nature (1994) 11.22
CD8+ T-cell responses to different HIV proteins have discordant associations with viral load. Nat Med (2006) 10.34
miR-181a is an intrinsic modulator of T cell sensitivity and selection. Cell (2007) 9.08
Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients. Blood (1995) 5.34
Estimating the precursor frequency of naive antigen-specific CD8 T cells. J Exp Med (2002) 5.16
Dynamic regulation of miRNA expression in ordered stages of cellular development. Genes Dev (2007) 4.79
Requirement for theta-bearing cells in lymphocytic choriomeningitis virus-induced central nervous system disease. Nature (1972) 4.08
Activated TCRs remain marked for internalization after dissociation from pMHC. Nat Immunol (2002) 3.01
The evolution of adaptive immune systems. Cell (2006) 2.77
Immunopathogenesis of acute central nervous system disease produced by lymphocytic choriomeningitis virus. II. Adoptive immunization of virus carriers. J Exp Med (1972) 2.68
Effect of HLA compatibility on engraftment of bone marrow transplants in patients with leukemia or lymphoma. N Engl J Med (1989) 2.61
Immunopathogenesis of acute central nervous system disease produced by lymphocytic choriomeningitis virus. I. Cyclophosphamide-mediated induction by the virus-carrier state in adult mice. J Exp Med (1972) 2.37
Ribosome-inactivating proteins from plants: present status and future prospects. Biotechnology (N Y) (1992) 1.84
Acute graft-vs-host disease: pathobiology and management. Exp Hematol (2001) 1.70
Intraparenchymal infusions of 192 IgG-saporin: development of a method for selective and discrete lesioning of cholinergic basal forebrain nuclei. J Neurosci Methods (1999) 1.52
Megadose of T cell-depleted bone marrow overcomes MHC barriers in sublethally irradiated mice. Nat Med (1995) 1.43
T cell receptor engagement leads to phosphorylation of clathrin heavy chain during receptor internalization. J Exp Med (2004) 1.19
Break of T cell ignorance to a viral antigen in the liver induces hepatitis. J Immunol (2000) 1.13
Immune T cells can protect or induce fatal neurological disease in murine lymphocytic choriomeningitis. Cell Immunol (1985) 1.10
Nature of the inflammatory process in the central nervous system of mice infected with lymphocytic choriomeningitis virus. Curr Top Microbiol Immunol (1987) 1.08
Regulation of constitutive TCR internalization by the zeta-chain. J Immunol (2002) 1.03
Selective deletion of antigen-specific CD8+ T cells by MHC class I tetramers coupled to the type I ribosome-inactivating protein saporin. Blood (2006) 0.96
Targeted deletion of T-cell clones using alpha-emitting suicide MHC tetramers. Blood (2004) 0.95
Virus-induced behavioral alteration of mice. Science (1977) 0.95
Lesions of the nucleus basalis magnocellularis induced by 192 IgG-saporin block memory enhancement with posttraining norepinephrine in the basolateral amygdala. Proc Natl Acad Sci U S A (2002) 0.93
Definition of a critical T cell threshold for prevention of GVHD after HLA non-identical PBPC transplantation in children. Bone Marrow Transplant (1999) 0.92
Immunotoxins containing recombinant anti-CTLA-4 single-chain fragment variable antibodies and saporin: in vitro results and in vivo effects in an acute rejection model. J Immunol (2001) 0.89
Characterization of a Saponaria officinalis seed ribosome-inactivating protein: immunoreactivity and sequence homologies. Biochem Biophys Res Commun (1985) 0.88
Remodeling specific immunity by use of MHC tetramers: demonstration in a graft-versus-host disease model. Blood (2005) 0.79
Modulation of the cellular immune response to intracerebral lymphocytic choriomeningitis virus (LCMV) infection in mice. Acta Microbiol Immunol Hung (1998) 0.77
Critical factors in optimizing graft-versus-leukemia effect for relapsed leukemias. J Clin Oncol (2002) 0.77
Restoring function in exhausted CD8 T cells during chronic viral infection. Nature (2005) 28.04
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature (2006) 20.00
Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nat Immunol (2003) 15.51
Lineage relationship and protective immunity of memory CD8 T cell subsets. Nat Immunol (2003) 15.51
Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment. J Virol (2003) 11.48
Molecular signature of CD8+ T cell exhaustion during chronic viral infection. Immunity (2007) 10.83
Rapid cloning of high-affinity human monoclonal antibodies against influenza virus. Nature (2008) 10.80
mTOR regulates memory CD8 T-cell differentiation. Nature (2009) 10.07
Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin. Nat Immunol (2005) 8.27
Molecular and functional profiling of memory CD8 T cell differentiation. Cell (2002) 8.06
The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection. Nat Immunol (2007) 7.60
Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection. J Exp Med (2011) 7.29
Memory CD8 T-cell differentiation during viral infection. J Virol (2004) 6.75
Redefining chronic viral infection. Cell (2009) 6.30
Systems biology of vaccination for seasonal influenza in humans. Nat Immunol (2011) 6.09
Liver-infiltrating lymphocytes in chronic human hepatitis C virus infection display an exhausted phenotype with high levels of PD-1 and low levels of CD127 expression. J Virol (2006) 6.00
Enhancing SIV-specific immunity in vivo by PD-1 blockade. Nature (2008) 5.94
Similarities and differences in CD4+ and CD8+ effector and memory T cell generation. Nat Immunol (2003) 5.90
Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates. J Exp Med (2008) 5.71
Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells. J Exp Med (2002) 5.64
Cutting edge: long-term B cell memory in humans after smallpox vaccination. J Immunol (2003) 5.51
Human effector and memory CD8+ T cell responses to smallpox and yellow fever vaccines. Immunity (2008) 5.22
Estimating the precursor frequency of naive antigen-specific CD8 T cells. J Exp Med (2002) 5.16
Tracking human antigen-specific memory B cells: a sensitive and generalized ELISPOT system. J Immunol Methods (2004) 4.57
Antigen-independent memory CD8 T cells do not develop during chronic viral infection. Proc Natl Acad Sci U S A (2004) 4.56
Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection. Proc Natl Acad Sci U S A (2010) 4.56
Cutting edge: rapid in vivo killing by memory CD8 T cells. J Immunol (2003) 4.25
Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity. J Exp Med (2006) 4.23
Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade. J Exp Med (2006) 4.17
Heterologous immunity provides a potent barrier to transplantation tolerance. J Clin Invest (2003) 4.14
Dynamic T cell migration program provides resident memory within intestinal epithelium. J Exp Med (2010) 4.09
Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo. Immunity (2010) 4.06
Translating innate immunity into immunological memory: implications for vaccine development. Cell (2006) 3.98
SAP is required for generating long-term humoral immunity. Nature (2003) 3.85
Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies. J Virol (2008) 3.83
Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo. Nat Med (2003) 3.68
Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys. J Clin Invest (2009) 3.55
Immunological mechanisms of vaccination. Nat Immunol (2011) 3.35
Cutting edge: gut microenvironment promotes differentiation of a unique memory CD8 T cell population. J Immunol (2006) 3.35
Diversity in T cell memory: an embarrassment of riches. Immunity (2009) 3.31
From vaccines to memory and back. Immunity (2010) 3.30
Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen. Nat Protoc (2009) 3.30
Stimulation history dictates memory CD8 T cell phenotype: implications for prime-boost vaccination. J Immunol (2006) 3.29
A Blueprint for HIV Vaccine Discovery. Cell Host Microbe (2012) 3.27
Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells. Proc Natl Acad Sci U S A (2012) 3.27
Tight regulation of memory CD8(+) T cells limits their effectiveness during sustained high viral load. Immunity (2011) 3.19
Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection. J Exp Med (2008) 2.81
Sensing and alarm function of resident memory CD8⁺ T cells. Nat Immunol (2013) 2.79
Antigen-independent differentiation and maintenance of effector-like resident memory T cells in tissues. J Immunol (2012) 2.70
The yellow fever virus vaccine induces a broad and polyfunctional human memory CD8+ T cell response. J Immunol (2009) 2.68
Regulation of homeostatic chemokine expression and cell trafficking during immune responses. Science (2007) 2.67
Visualizing antigen-specific and infected cells in situ predicts outcomes in early viral infection. Science (2009) 2.64
Recombinant vaccinia virus-induced T-cell immunity: quantitation of the response to the virus vector and the foreign epitope. J Virol (2002) 2.64
Continuous recruitment of naive T cells contributes to heterogeneity of antiviral CD8 T cells during persistent infection. J Exp Med (2006) 2.55
Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells. Immunity (2011) 2.49
Memory CD8 T-cell compartment grows in size with immunological experience. Nature (2008) 2.49
The role of models in understanding CD8+ T-cell memory. Nat Rev Immunol (2005) 2.43
High antigen levels are the cause of T cell exhaustion during chronic viral infection. Proc Natl Acad Sci U S A (2009) 2.42
Features of responding T cells in cancer and chronic infection. Curr Opin Immunol (2010) 2.42
The role of programming in memory T-cell development. Curr Opin Immunol (2004) 2.41
Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection. Proc Natl Acad Sci U S A (2007) 2.39
Immune responses to Bacillus anthracis protective antigen in patients with bioterrorism-related cutaneous or inhalation anthrax. J Infect Dis (2004) 2.29
Differential sensitivity of naive and memory CD8+ T cells to apoptosis in vivo. J Immunol (2002) 2.26
Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8+ T cells. Nat Immunol (2013) 2.23
Elevated expression levels of inhibitory receptor programmed death 1 on simian immunodeficiency virus-specific CD8 T cells during chronic infection but not after vaccination. J Virol (2007) 2.21
Critical Role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function. Immunity (2012) 2.16
Case of yellow fever vaccine--associated viscerotropic disease with prolonged viremia, robust adaptive immune responses, and polymorphisms in CCR5 and RANTES genes. J Infect Dis (2008) 2.14
Proteome-wide analysis of the serological response to vaccinia and smallpox. Proteomics (2007) 2.10
Generation and maintenance of immunological memory. Semin Immunol (2004) 2.06
Low CD8 T-cell proliferative potential and high viral load limit the effectiveness of therapeutic vaccination. J Virol (2005) 2.06
Distinct memory CD4+ T cells with commitment to T follicular helper- and T helper 1-cell lineages are generated after acute viral infection. Immunity (2013) 2.05
Strength of stimulus and clonal competition impact the rate of memory CD8 T cell differentiation. J Immunol (2007) 2.04
Cutting edge: intravascular staining redefines lung CD8 T cell responses. J Immunol (2012) 1.99
Bone marrow is a preferred site for homeostatic proliferation of memory CD8 T cells. J Immunol (2005) 1.95
Immunological memory in humans. Semin Immunol (2004) 1.90
Evidence that a significant number of naive T cells enter non-lymphoid organs as part of a normal migratory pathway. Eur J Immunol (2006) 1.87
Role of CD4 T cell help and costimulation in CD8 T cell responses during Listeria monocytogenes infection. J Immunol (2003) 1.83
NFATc1 regulates PD-1 expression upon T cell activation. J Immunol (2008) 1.81
Quantitating the magnitude of the lymphocytic choriomeningitis virus-specific CD8 T-cell response: it is even bigger than we thought. J Virol (2006) 1.78
Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection. J Virol (2009) 1.77
Rapid and massive virus-specific plasmablast responses during acute dengue virus infection in humans. J Virol (2012) 1.74
Accelerating next-generation vaccine development for global disease prevention. Science (2013) 1.73
Changing immunodominance patterns in antiviral CD8 T-cell responses after loss of epitope presentation or chronic antigenic stimulation. Virology (2003) 1.69
Phenotype, function, and gene expression profiles of programmed death-1(hi) CD8 T cells in healthy human adults. J Immunol (2011) 1.66
Defective generation but normal maintenance of memory T cells in old mice. Eur J Immunol (2002) 1.64
Identification of an evolutionarily conserved transcriptional signature of CD8 memory differentiation that is shared by T and B cells. J Immunol (2008) 1.63
Antigen-specific CD4 T-cell help rescues exhausted CD8 T cells during chronic viral infection. Proc Natl Acad Sci U S A (2011) 1.62
BCL6b mediates the enhanced magnitude of the secondary response of memory CD8+ T lymphocytes. Proc Natl Acad Sci U S A (2005) 1.61
Requirement of B cells for generating CD4+ T cell memory. J Immunol (2009) 1.60
Differentiation of memory B and T cells. Curr Opin Immunol (2006) 1.59
A specific role for B cells in the generation of CD8 T cell memory by recombinant Listeria monocytogenes. J Immunol (2003) 1.59