Published in Transl Res on July 14, 2009
Prevention of alveolar destruction and airspace enlargement in a mouse model of pulmonary lymphangioleiomyomatosis (LAM). Sci Transl Med (2012) 1.03
Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling? Transl Res (2010) 0.99
Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease. Pharmacol Ther (2014) 0.90
Transforming growth factor-β-induced differentiation of airway smooth muscle cells is inhibited by fibroblast growth factor-2. Am J Respir Cell Mol Biol (2012) 0.90
Probing ligand-binding pockets of the mevalonate pathway enzymes from Streptococcus pneumoniae. J Biol Chem (2010) 0.90
Transgenic expression of human S100A12 induces structural airway abnormalities and limited lung inflammation in a mouse model of allergic inflammation. Clin Exp Allergy (2011) 0.86
Caveolins and lung function. Adv Exp Med Biol (2012) 0.84
PPARγ Ligands Regulate Noncontractile and Contractile Functions of Airway Smooth Muscle: Implications for Asthma Therapy. PPAR Res (2012) 0.84
Plasminogen-stimulated airway smooth muscle cell proliferation is mediated by urokinase and annexin A2, involving plasmin-activated cell signalling. Br J Pharmacol (2013) 0.83
Recombinant rat CC10 protein inhibits PDGF-induced airway smooth muscle cells proliferation and migration. Biomed Res Int (2013) 0.82
Thymic stromal lymphopoietin induces migration in human airway smooth muscle cells. Sci Rep (2013) 0.79
A polymorphism in HLA-G modifies statin benefit in asthma. Pharmacogenomics J (2014) 0.79
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Giant Cell Arteritis: From Pathogenesis to Therapeutic Management. Curr Treatm Opt Rheumatol (2016) 0.77
Organ-derived coatings on electrospun nanofibers as ex vivo microenvironments. Biomaterials (2010) 0.76
S100A12 and the Airway Smooth Muscle: Beyond Inflammation and Constriction. J Allergy Ther (2012) 0.75
Bitter Taste Receptor Agonists Alter Mitochondrial Function and Induce Autophagy in Airway Smooth Muscle Cells. Am J Physiol Lung Cell Mol Physiol (2017) 0.75
SLCO1B1 variants and statin-induced myopathy--a genomewide study. N Engl J Med (2008) 11.31
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Influenza and COPD mortality protection as pleiotropic, dose-dependent effects of statins. Chest (2007) 4.96
Asthma control during the year after bronchial thermoplasty. N Engl J Med (2007) 4.79
Identification of circulating fibrocytes as precursors of bronchial myofibroblasts in asthma. J Immunol (2003) 4.69
TGF-beta1 induces human alveolar epithelial to mesenchymal cell transition (EMT). Respir Res (2005) 4.24
Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression. Am J Respir Crit Care Med (2004) 2.93
Prior statin therapy is associated with a decreased rate of severe sepsis. Circulation (2004) 2.82
Cellular hypertrophy and hyperplasia of airway smooth muscles underlying bronchial asthma. A 3-D morphometric study. Am Rev Respir Dis (1993) 2.69
Epithelial origin of myofibroblasts during fibrosis in the lung. Proc Am Thorac Soc (2006) 2.61
Measurement in vivo of proliferation rates of slow turnover cells by 2H2O labeling of the deoxyribose moiety of DNA. Proc Natl Acad Sci U S A (2002) 2.46
The role of the mast cell in the pathophysiology of asthma. J Allergy Clin Immunol (2006) 2.35
Airway smooth muscle cell proliferation is increased in asthma. Am J Respir Crit Care Med (2001) 2.34
Omalizumab for asthma. N Engl J Med (2006) 2.31
Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma. Eur Respir J (2007) 2.16
An assessment of statin safety by muscle experts. Am J Cardiol (2006) 2.16
An HMG-CoA reductase inhibitor, cerivastatin, suppresses growth of macrophages expressing matrix metalloproteinases and tissue factor in vivo and in vitro. Circulation (2001) 2.09
Host bone-marrow cells are a source of donor intimal smooth- muscle-like cells in murine aortic transplant arteriopathy. Nat Med (2001) 1.96
A novel anti-inflammatory role of simvastatin in a murine model of allergic asthma. J Immunol (2004) 1.88
Evidence for tissue-resident mesenchymal stem cells in human adult lung from studies of transplanted allografts. J Clin Invest (2007) 1.87
Lymphangioleiomyomatosis: A review. Eur J Intern Med (2007) 1.80
Epithelial-mesenchymal communication in the pathogenesis of chronic asthma. Proc Am Thorac Soc (2004) 1.68
Statin use is associated with reduced mortality in COPD. Eur Respir J (2006) 1.66
Increased circulating fibrocytes in asthma with chronic airflow obstruction. Am J Respir Crit Care Med (2008) 1.65
Simvastatin rescues rats from fatal pulmonary hypertension by inducing apoptosis of neointimal smooth muscle cells. Circulation (2003) 1.63
Potential therapeutic role for statins in respiratory disease. Thorax (2006) 1.49
Detection of epithelial to mesenchymal transition in airways of a bleomycin induced pulmonary fibrosis model derived from an alpha-smooth muscle actin-Cre transgenic mouse. Respir Res (2007) 1.46
Airway smooth muscle in asthma. Annu Rev Pathol (2008) 1.45
Isolation of an adult mouse lung mesenchymal progenitor cell population. Am J Respir Cell Mol Biol (2007) 1.45
Rho and vascular disease. Atherosclerosis (2005) 1.42
New targets for drug development in asthma. Lancet (2008) 1.38
Attenuation of chronic hypoxic pulmonary hypertension by simvastatin. Am J Physiol Heart Circ Physiol (2003) 1.34
Mast cells promote airway smooth muscle cell differentiation via autocrine up-regulation of TGF-beta 1. J Immunol (2008) 1.34
Regression of chronic hypoxic pulmonary hypertension by simvastatin. Am J Physiol Lung Cell Mol Physiol (2007) 1.30
Antileukotriene drugs: clinical application, effectiveness and safety. Curr Med Chem (2007) 1.29
Effects of atorvastatin added to inhaled corticosteroids on lung function and sputum cell counts in atopic asthma. Thorax (2008) 1.26
Tissue fibrocytes in patients with mild asthma: a possible link to thickness of reticular basement membrane? Respir Res (2006) 1.25
Abnormal growth of smooth muscle-like cells in lymphangioleiomyomatosis: Role for tumor suppressor TSC2. Am J Respir Cell Mol Biol (2006) 1.24
Structural changes in the airways in asthma: observations and consequences. Clin Sci (Lond) (2005) 1.24
Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: cooperative roles for CADM1, stem cell factor, and IL-6. J Immunol (2008) 1.23
Radiofrequency ablation of airway smooth muscle for sustained treatment of asthma: preliminary investigations. Eur Respir J (2004) 1.21
Simvastatin does not exhibit therapeutic anti-inflammatory effects in asthma. J Allergy Clin Immunol (2006) 1.21
Statins may reduce episodes of exacerbation and the requirement for intubation in patients with COPD: evidence from a retrospective cohort study. Int J Clin Pract (2008) 1.20
The use of statins and lung function in current and former smokers. Chest (2007) 1.18
Simvastatin treatment of pulmonary hypertension: an observational case series. Chest (2005) 1.15
Stretch-induced alternative splicing of serum response factor promotes bronchial myogenesis and is defective in lung hypoplasia. J Clin Invest (2000) 1.14
FIZZ1 plays a crucial role in early stage airway remodeling of OVA-induced asthma. J Asthma (2008) 1.11
Dual-immunohistochemistry provides little evidence for epithelial-mesenchymal transition in pulmonary fibrosis. Histochem Cell Biol (2008) 1.10
Role of RhoA inactivation in reduced cell proliferation of human airway smooth muscle by simvastatin. Am J Respir Cell Mol Biol (2006) 1.07
Airway smooth muscle: the appendix of the lung. Am J Respir Crit Care Med (2004) 1.02
Airway smooth muscle in bronchial tone, inflammation, and remodeling: basic knowledge to clinical relevance. Am J Respir Crit Care Med (2007) 1.02
Simvastatin suppresses self-renewal of mouse embryonic stem cells by inhibiting RhoA geranylgeranylation. Stem Cells (2007) 1.02
A prospective feasibility study of bronchial thermoplasty in the human airway. Chest (2005) 1.02
The role of airway smooth muscle in the pathogenesis of airway wall remodeling in chronic obstructive pulmonary disease. Proc Am Thorac Soc (2005) 1.01
Phenotype and functional plasticity of airway smooth muscle: role of caveolae and caveolins. Proc Am Thorac Soc (2008) 1.01
Comparison of the efficacies of five different statins on inhibition of human saphenous vein smooth muscle cell proliferation and invasion. J Cardiovasc Pharmacol (2007) 1.00
Migration of airway smooth muscle cells. Proc Am Thorac Soc (2008) 0.99
Airway proteoglycans are differentially altered in fatal asthma. J Pathol (2005) 0.98
Rosuvastatin regulates vascular smooth muscle cell phenotypic modulation in vascular remodeling: role for the urokinase receptor. Atherosclerosis (2007) 0.96
Treating asthma means treating airway smooth muscle cells. Eur Respir J (2008) 0.95
Combined smooth muscle and melanocytic differentiation in lymphangioleiomyomatosis. J Histochem Cytochem (2004) 0.94
Inhibitors of HMG-CoA reductase sensitize human smooth muscle cells to Fas-ligand and cytokine-induced cell death. Atherosclerosis (2000) 0.93
Statin withdrawal: clinical implications and molecular mechanisms. Pharmacotherapy (2006) 0.93
Development of the innervation and airway smooth muscle in human fetal lung. Am J Respir Cell Mol Biol (1999) 0.93
Peripheral airway smooth muscle mechanics in obstructive airways disease. Am J Respir Crit Care Med (2000) 0.91
Smooth muscle-like cells in pulmonary lymphangioleiomyomatosis. Proc Am Thorac Soc (2008) 0.91
Embryonic lung side population cells are hematopoietic and vascular precursors. Am J Respir Cell Mol Biol (2005) 0.91
Transforming growth factor-beta1 and disorders of the lung. Cell Biochem Biophys (2005) 0.89
Proteinase-activated receptor 4 stimulation-induced epithelial-mesenchymal transition in alveolar epithelial cells. Respir Res (2007) 0.89
Retinoic acid inhibits airway smooth muscle cell migration. Am J Respir Cell Mol Biol (2006) 0.88
Statins effect on smooth muscle cell proliferation. Semin Vasc Med (2004) 0.85
A therapeutic dose of the lipophilic statin pitavastatin enhances oxidant-induced apoptosis in human vascular smooth muscle cells. J Cardiovasc Pharmacol (2006) 0.85
The effects of HMG-CoA reductase inhibitor on vascular progenitor cells. J Pharmacol Sci (2006) 0.85
Effects of various statins on cytokine-dependent growth and IgE-dependent release of histamine in human mast cells. Allergy (2006) 0.85
Fas cross-linking induces apoptosis in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol (2000) 0.84
Transforming growth factor-beta 1 and extracellular matrix-associated fibronectin expression in pulmonary lymphangioleiomyomatosis. Chest (2004) 0.84
Translational regulation of gene expression by omega-3 fatty acids. J Nutr (2004) 0.84
Stem cells in airway smooth muscle: state of the art. Proc Am Thorac Soc (2008) 0.83
Induction of human airway smooth muscle apoptosis by neutrophils and neutrophil elastase. Am J Respir Cell Mol Biol (2005) 0.82
The effect of six different statins on the proliferation, migration, and invasion of human smooth muscle cells. J Surg Res (2005) 0.82
Efficacy and tolerability of lovastatin in 3390 women with moderate hypercholesterolemia. Ann Intern Med (1993) 0.81
HMG-CoA reductase inhibitor simvastatin inhibits proinflammatory cytokine production from murine mast cells. Int Arch Allergy Immunol (2008) 0.81
Novel therapies for children with severe asthma. Curr Opin Pediatr (2008) 0.80
Effects of decorin and biglycan on human airway smooth muscle cell proliferation and apoptosis. Am J Physiol Lung Cell Mol Physiol (2008) 0.80
Upregulation of angiotensin II-AT1 receptors during statin withdrawal in vascular smooth muscle cells. J Cardiovasc Pharmacol (2007) 0.80
Measurement of mouse vascular smooth muscle and atheroma cell proliferation by 2H2O incorporation into DNA. Am J Physiol Cell Physiol (2006) 0.79