Emerging role of Notch signaling in epidermal differentiation and skin cancer.

PubWeight™: 0.97‹?› | Rank: Top 15%

🔗 View Article (PMID 19783903)

Published in Cancer Biol Ther on November 26, 2009

Authors

John Panelos1, Daniela Massi

Author Affiliations

1: Department of Pathology, University of Ioannina Medical School, Ioannina, Greece.

Articles citing this

Targeting Notch signaling pathway to overcome drug resistance for cancer therapy. Biochim Biophys Acta (2010) 1.59

Smoking and risk of skin cancer: a prospective analysis and a meta-analysis. Int J Epidemiol (2012) 1.16

At the crossroads of differentiation and proliferation: precise control of cell-cycle changes by multiple signaling pathways in Drosophila follicle cells. Bioessays (2011) 1.11

Overabundance of putative cancer stem cells in human skin keratinocyte cells malignantly transformed by arsenic. Toxicol Sci (2011) 0.96

The emerging importance of α-L-fucose in human breast cancer: a review. Am J Transl Res (2011) 0.89

Functional Variants in Notch Pathway Genes NCOR2, NCSTN, and MAML2 Predict Survival of Patients with Cutaneous Melanoma. Cancer Epidemiol Biomarkers Prev (2015) 0.87

Morbidity risks among older adults with pre-existing age-related diseases. Exp Gerontol (2013) 0.87

Lysyl oxidase-like 2 represses Notch1 expression in the skin to promote squamous cell carcinoma progression. EMBO J (2015) 0.84

Capturing the biological impact of CDKN2A and MC1R genes as an early predisposing event in melanoma and non melanoma skin cancer. Oncotarget (2014) 0.84

Clonal expansion analysis of transposon insertions by high-throughput sequencing identifies candidate cancer genes in a PiggyBac mutagenesis screen. PLoS One (2013) 0.82

Eph/ephrin signaling in epidermal differentiation and disease. Semin Cell Dev Biol (2011) 0.82

Chemotherapy in the management of advanced cutaneous malignant melanoma. Clin Dermatol (2013) 0.79

Canonical Notch signalling is inactive in urothelial carcinoma. BMC Cancer (2014) 0.78

Drosophila as a tool for personalized medicine: a primer. Per Med (2010) 0.77

Novel vitamin D compounds and skin cancer prevention. Dermatoendocrinol (2013) 0.77

Activated Notch1 expression is associated with angiogenesis in cutaneous melanoma. Clin Exp Med (2014) 0.77

Inhibition of BMP signaling in P-Cadherin positive hair progenitor cells leads to trichofolliculoma-like hair follicle neoplasias. J Biomed Sci (2011) 0.76

Anticancer properties of phospholipase A2 from Daboia siamensis venom on human skin melanoma cells. J Venom Anim Toxins Incl Trop Dis (2016) 0.75

Articles by these authors

Application of a filtration- and isolation-by-size technique for the detection of circulating tumor cells in cutaneous melanoma. J Invest Dermatol (2010) 3.26

BRAF/NRAS mutation frequencies among primary tumors and metastases in patients with melanoma. J Clin Oncol (2012) 2.41

Pigmented Bowen's disease mimicking cutaneous melanoma: clinical and dermoscopic aspects. Dermatol Surg (2004) 2.29

Cigarette smoke-induced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents. J Clin Invest (2008) 2.20

Dermoscopy improves accuracy of primary care physicians to triage lesions suggestive of skin cancer. J Clin Oncol (2006) 1.81

MC1R variants increase risk of melanomas harboring BRAF mutations. J Invest Dermatol (2008) 1.72

Estrogen receptor expression in cutaneous melanoma: a real-time reverse transcriptase-polymerase chain reaction and immunohistochemical study. Arch Dermatol (2009) 1.67

Fluorescence in situ hybridization, a diagnostic aid in ambiguous melanocytic tumors: European study of 113 cases. Mod Pathol (2010) 1.52

Circulating benign nevus cells detected by ISET technique: warning for melanoma molecular diagnosis. Arch Dermatol (2010) 1.46

Clinically and dermoscopically featureless melanoma: when prevention fails. J Am Acad Dermatol (2002) 1.41

The role of estrogens in melanoma and skin cancer. Carcinogenesis (2009) 1.38

Tumor lymphangiogenesis in head and neck squamous cell carcinoma: a morphometric study with clinical correlations. Cancer (2004) 1.35

Dermoscopy for "true" amelanotic melanoma: a clinical dermoscopic-pathologic case study. J Am Acad Dermatol (2006) 1.33

Scoring of collagen organization in healthy and diseased human dermis by multiphoton microscopy. J Biophotonics (2010) 1.30

Sinonasal undifferentiated carcinoma, nasopharyngeal-type undifferentiated carcinoma, and keratinizing and nonkeratinizing squamous cell carcinoma express different cytokeratin patterns. Am J Surg Pathol (2002) 1.27

Vulvar basal cell carcinoma: retrospective study and review of literature. Gynecol Oncol (2005) 1.23

Beclin 1 and LC3 autophagic gene expression in cutaneous melanocytic lesions. Hum Pathol (2009) 1.22

Melanomas that failed dermoscopic detection: a combined clinicodermoscopic approach for not missing melanoma. Dermatol Surg (2007) 1.17

Cytotoxic/natural killer cell cutaneous lymphomas. Report of EORTC Cutaneous Lymphoma Task Force Workshop. Cancer (2003) 1.15

Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents. FASEB J (2010) 1.12

Dermoscopy in pigmented squamous cell carcinoma. J Cutan Med Surg (2009) 1.10

Images in clinical medicine. Plantar melanoma--a false vegetant wart. N Engl J Med (2006) 1.09

Increase in FOXP3+ regulatory T cells in GVHD skin biopsies is associated with lower disease severity and treatment response. Biol Blood Marrow Transplant (2009) 1.07

False "melanocytic" parameters shown by pigmented seborrheic keratoses: a finding which is not uncommon in dermoscopy. Dermatol Surg (2002) 1.04

Inducible nitric oxide synthase activity correlates with lymphangiogenesis and vascular endothelial growth factor-C expression in head and neck squamous cell carcinoma. J Pathol (2006) 1.00

Keratinocyte dysfunction in vitiligo epidermis: cytokine microenvironment and correlation to keratinocyte apoptosis. Histol Histopathol (2009) 0.98

BRAFV600E detection in melanoma is highly improved by COLD-PCR. Clin Chim Acta (2011) 0.98

Protease-activated receptor 1-selective antagonist SCH79797 inhibits cell proliferation and induces apoptosis by a protease-activated receptor 1-independent mechanism. Basic Clin Pharmacol Toxicol (2007) 0.97

β-adrenoceptors are upregulated in human melanoma and their activation releases pro-tumorigenic cytokines and metalloproteases in melanoma cell lines. Lab Invest (2013) 0.97

Multiparametric analysis of cell-free DNA in melanoma patients. PLoS One (2012) 0.97

Circulating cell-free DNA in plasma of melanoma patients: qualitative and quantitative considerations. Clin Chim Acta (2011) 0.96

Immediate local and regional recurrence after the excision of a polypoid melanoma: tumor dormancy or tumor activation? Dermatol Surg (2003) 0.96

Tissue prognostic biomarkers in primary cutaneous melanoma. Virchows Arch (2014) 0.96

Spectral morphological analysis of skin lesions with a polarization multispectral dermoscope. Opt Express (2013) 0.96

Keratinocyte growth factor receptors. Dermatol Clin (2007) 0.95

Histopathology report of cutaneous melanoma and sentinel lymph node in Europe: a web-based survey by the Dermatopathology Working Group of the European Society of Pathology. Virchows Arch (2009) 0.93

Giant melanoma displaying gross features reproducing parameters seen on dermoscopy. Dermatol Surg (2002) 0.93

Dermoscopic features of mucosal melanosis. Dermatol Surg (2004) 0.93

Expression of Notch-1 and alteration of the E-cadherin/beta-catenin cell adhesion complex are observed in primary cutaneous neuroendocrine carcinoma (Merkel cell carcinoma). Mod Pathol (2009) 0.92

Thin melanoma of the vulva: a clinical, dermoscopic-pathologic case study. Arch Dermatol (2005) 0.92

Heterogeneous distribution of BRAF/NRAS mutations among Italian patients with advanced melanoma. J Transl Med (2013) 0.92

Superficial cutaneous leiomyosarcoma: a rare, misleading tumor. Am J Clin Dermatol (2008) 0.91

In vivo characterization of the inflammatory infiltrate and apoptotic status in imiquimod-treated basal cell carcinoma. Int J Dermatol (2009) 0.91

Possible histopathologic correlates of dermoscopic features in pigmented melanocytic lesions identified by means of optical coherence tomography. Exp Dermatol (2005) 0.90

Bullous pilomatricoma: a particular and rare dermal bullous disorder. Acta Derm Venereol (2009) 0.90

Application of optical coherence tomography in non-invasive characterization of skin vascular lesions. Skin Res Technol (2008) 0.90

In vivo non-invasive monitoring of collagen remodelling by two-photon microscopy after micro-ablative fractional laser resurfacing. J Biophotonics (2013) 0.90

Dilation of intercellular spaces is associated with laryngo-pharyngeal reflux: an ultrastructural morphometric analysis of laryngeal epithelium. Eur Arch Otorhinolaryngol (2007) 0.90

Frequent loss of expression of the cyclin-dependent kinase inhibitor p27(Kip1) in estrogen-related Endometrial adenocarcinomas. Clin Cancer Res (2003) 0.89

Substance P released by TRPV1-expressing neurons produces reactive oxygen species that mediate ethanol-induced gastric injury. Free Radic Biol Med (2007) 0.89

The Wilms' tumor suppressor WT1 is associated with melanoma proliferation. Pflugers Arch (2007) 0.88

Features of regression in dermoscopic diagnosis: a confounding factor? Two clinical, dermoscopic-pathologic case studies. Dermatol Surg (2006) 0.88

CDX-2 homeobox gene expression. Am J Surg Pathol (2003) 0.88

Paraganglioma of the nasal cavity: a case report. Eur Arch Otorhinolaryngol (2003) 0.88

Features of small melanocytic lesions: does small mean benign? A clinical-dermoscopic study. Melanoma Res (2012) 0.88

Sebaceous carcinoma arising from nevus sebaceus: a case report. Dermatol Surg (2003) 0.87

Estrogens, estrogen receptors and melanoma. Expert Rev Anticancer Ther (2011) 0.87

Hyalinizing spindle cell tumor with giant rosettes and low-grade fibromyxoid sarcoma: an immunohistochemical and ultrastructural comparative investigation. Ultrastruct Pathol (2004) 0.87

Tyrosinase mRNA levels in the blood of uveal melanoma patients: correlation with the number of circulating tumor cells and tumor progression. Melanoma Res (2010) 0.85

Cutaneous pseudolymphoma localized to black tattoo. J Am Acad Dermatol (2011) 0.85

Caveolin-1 as a promoter of tumour spreading: when, how, where and why. J Cell Mol Med (2013) 0.84

Skin metastasis from typical carcinoid tumor of the lung. J Cutan Pathol (2008) 0.83

Expression of cyclo-oxygenase-2 in macrophages associated with cutaneous melanoma at different stages of progression. Prostaglandins Other Lipid Mediat (2007) 0.83

Allele specific Taqman-based real-time PCR assay to quantify circulating BRAFV600E mutated DNA in plasma of melanoma patients. Clin Chim Acta (2010) 0.83

Insight into the pathogenesis of sporadic basal cell carcinoma. Int J Dermatol (2004) 0.82

Solitary cutaneous metastasis as the first sign of relapse of thyroid carcinoma: a clinical, dermoscopic-pathologic case study. Dermatol Surg (2009) 0.82

Dermoscopy in the management of pigmented lesions of the oral mucosa. Oral Oncol (2003) 0.82

The release of fibroblast growth factor-1 from melanoma cells requires copper ions and is mediated by phosphatidylinositol 3-kinase/Akt intracellular signaling pathway. Cancer Lett (2008) 0.81

Influence of sex hormones on melanoma. J Clin Oncol (2010) 0.81

Photoexposition discriminates Notch 1 expression in human cutaneous squamous cell carcinoma. Mod Pathol (2008) 0.81

A 10-year-old in situ melanoma? Arch Dermatol (2002) 0.80

Polymorphisms of estrogen receptors: risk factors for invasive melanoma - a prospective study. Oncology (2011) 0.80

Rhabdomyosarcoma of the skin resembling carcinosarcoma: report of a case and literature review. Am J Dermatopathol (2012) 0.80

The prognostic impact of the anatomical sites in the 'head and neck melanoma': scalp versus face and neck. Melanoma Res (2012) 0.80

Melanoma of the penis: a clinical dermoscopic case study. Acta Derm Venereol (2010) 0.80

Fluorescence in-situ hybridization analysis for melanoma diagnosis. Histopathology (2011) 0.80

Incidental finding: a penile cutaneous horn. Acta Derm Venereol (2005) 0.80

Eccrine porocarcinoma: a rare but sometimes fatal malignant neoplasm. Dermatol Surg (2007) 0.80

Blue hue in the dermoscopy setting: homogeneous blue pigmentation, gray-blue area, and/or whitish blue veil? Dermatol Surg (2003) 0.80

Iatrogenic calcinosis cutis following nadroparin injection. Int J Dermatol (2005) 0.79

Subungual melanoma: a particularly invasive "onychomycosis". J Am Geriatr Soc (2007) 0.79

PPARbeta activation inhibits melanoma cell proliferation involving repression of the Wilms' tumour suppressor WT1. Pflugers Arch (2010) 0.79

Cutaneous metastases: an ominous sign of urothelial carcinoma of the bladder. Dermatol Surg (2008) 0.79

Tumour suppressor gene TP53 mutations in atypical vascular lesions of breast skin following radiotherapy. Histopathology (2011) 0.78

Eruptive multiple blue nevi of the penis: a clinical dermoscopic pathologic case study. J Cutan Pathol (2004) 0.78

Exocrine and endocrine modulation in common gastric carcinoma. Am J Clin Pathol (2012) 0.78

Development of a human in vivo method to study the effect of ultraviolet radiation and sunscreens in melanocytic nevi. Dermatology (2008) 0.78

Efficacy of treatment with oral alitretinoin in patient suffering from lichen simplex chronicus and severe atopic dermatitis of hands. Dermatol Ther (2013) 0.78

A molecular and computational diagnostic approach identifies FOXP3, ICOS, CD52 and CASP1 as the most informative biomarkers in acute graft-versus-host disease. Haematologica (2012) 0.77

Orbital solitary fibrous tumor: a case report and review of the literature. Pathol Oncol Res (2008) 0.77

Expression of p16 in sinonasal malignant melanoma. Virchows Arch (2006) 0.77

Ungual basal cell carcinoma on the fifth toe mimicking chronic dermatitis: case study. Dermatol Surg (2005) 0.77

Immunohistochemical study of carbonic anhydrase isozymes in human skin. Eur J Dermatol (2003) 0.77

Results of surveillance programme aimed at early diagnosis of cutaneous melanoma in high risk Mediterranean subjects. Eur J Dermatol (2003) 0.77

The comparative role of immunohistochemistry and electron microscopy in the identification of myogenic differentiation in soft tissue pleomorphic sarcomas. Ultrastruct Pathol (2005) 0.77

Discrepant alterations in main candidate genes among multiple primary melanomas. J Transl Med (2014) 0.77

Melanocytic aggregation in the skin: diagnostic clues from lentigines to melanoma. Dermatol Clin (2007) 0.77

What can hide under exophytic verrucous appearance? Acta Derm Venereol (2011) 0.77

Kimura's disease: case report of an Italian young male and response to oral cyclosporine A in an 8 years follow-up. Clin Rheumatol (2010) 0.76